ciclopirox has been researched along with Leukemia in 1 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our existing study demonstrated that Ciclopirox Olamine (CPX), an off-patent antifungal agent, effectively elevated the expression of NKG2DLs on leukemia cells and sensitized leukemia cells to NK-cell mediated cytolysis." | 8.31 | Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway. ( Fan, D; Ju, X; Kong, L; Li, Y; Su, G; Wang, D; Xue, M; Yang, Q; Yu, M; Zhang, S; Zhao, Z; Zhou, H; Zhu, H; Zhu, Y, 2023) |
| " Our existing study demonstrated that Ciclopirox Olamine (CPX), an off-patent antifungal agent, effectively elevated the expression of NKG2DLs on leukemia cells and sensitized leukemia cells to NK-cell mediated cytolysis." | 4.31 | Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway. ( Fan, D; Ju, X; Kong, L; Li, Y; Su, G; Wang, D; Xue, M; Yang, Q; Yu, M; Zhang, S; Zhao, Z; Zhou, H; Zhu, H; Zhu, Y, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 1 |
| Zhao, Z | 1 |
| Xue, M | 1 |
| Wang, D | 1 |
| Su, G | 1 |
| Ju, X | 1 |
| Yang, Q | 1 |
| Zhang, S | 1 |
| Fan, D | 1 |
| Zhu, H | 1 |
| Yu, M | 1 |
| Li, Y | 1 |
| Kong, L | 1 |
| Zhou, H | 1 |
1 other study available for ciclopirox and Leukemia
| Article | Year |
|---|---|
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway.
Topics: Cell Line, Tumor; Ciclopirox; Humans; Killer Cells, Natural; Leukemia; NK Cell Lectin-Like Receptor | 2023 |