Page last updated: 2024-10-25

ciclopirox and Leukemia

ciclopirox has been researched along with Leukemia in 1 studies

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
" Our existing study demonstrated that Ciclopirox Olamine (CPX), an off-patent antifungal agent, effectively elevated the expression of NKG2DLs on leukemia cells and sensitized leukemia cells to NK-cell mediated cytolysis."8.31Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway. ( Fan, D; Ju, X; Kong, L; Li, Y; Su, G; Wang, D; Xue, M; Yang, Q; Yu, M; Zhang, S; Zhao, Z; Zhou, H; Zhu, H; Zhu, Y, 2023)
" Our existing study demonstrated that Ciclopirox Olamine (CPX), an off-patent antifungal agent, effectively elevated the expression of NKG2DLs on leukemia cells and sensitized leukemia cells to NK-cell mediated cytolysis."4.31Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway. ( Fan, D; Ju, X; Kong, L; Li, Y; Su, G; Wang, D; Xue, M; Yang, Q; Yu, M; Zhang, S; Zhao, Z; Zhou, H; Zhu, H; Zhu, Y, 2023)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Zhu, Y1
Zhao, Z1
Xue, M1
Wang, D1
Su, G1
Ju, X1
Yang, Q1
Zhang, S1
Fan, D1
Zhu, H1
Yu, M1
Li, Y1
Kong, L1
Zhou, H1

Other Studies

1 other study available for ciclopirox and Leukemia

ArticleYear
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway.
    Biochemical and biophysical research communications, 2023, 06-04, Volume: 659

    Topics: Cell Line, Tumor; Ciclopirox; Humans; Killer Cells, Natural; Leukemia; NK Cell Lectin-Like Receptor

2023