ci 994 has been researched along with Osteolysis in 1 studies
tacedinaline: oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells
tacedinaline : A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
Osteolysis: Dissolution of bone that particularly involves the removal or loss of calcium.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, D | 1 |
| Hong, D | 1 |
| Wang, P | 1 |
| Wang, J | 1 |
| Chen, L | 1 |
| Zhao, W | 1 |
| Zhang, L | 1 |
| Yao, C | 1 |
| Chu, B | 1 |
| Chen, S | 1 |
| Li, Z | 1 |
| Chen, H | 1 |
1 other study available for ci 994 and Osteolysis
| Article | Year |
|---|---|
Histone deacetylase inhibitor CI-994 inhibits osteoclastogenesis via suppressing NF-κB and the downstream c-Fos/NFATc1 signaling pathways.
Topics: Animals; Benzamides; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Histon | 2019 |