ci 994 has been researched along with Medulloblastoma in 1 studies
tacedinaline: oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells
tacedinaline : A benzamide obtained by formal condensation of the carboxy group of 4-acetamidobenzoic acid with one of the amino groups of 1,2-phenylenediamine. An oral cytostatic drug with impressive differential activity against leukemic cells and normal stem-cells. Also used in combination therapy for selected tumors including non-smoll cell lung, pancreatic, breast, and colorectal cancers.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marquardt, V | 1 |
| Theruvath, J | 1 |
| Pauck, D | 1 |
| Picard, D | 1 |
| Qin, N | 1 |
| Blümel, L | 1 |
| Maue, M | 1 |
| Bartl, J | 1 |
| Ahmadov, U | 1 |
| Langini, M | 1 |
| Meyer, FD | 1 |
| Cole, A | 1 |
| Cruz-Cruz, J | 1 |
| Graef, CM | 1 |
| Wölfl, M | 1 |
| Milde, T | 1 |
| Witt, O | 1 |
| Erdreich-Epstein, A | 1 |
| Leprivier, G | 1 |
| Kahlert, U | 1 |
| Stefanski, A | 1 |
| Stühler, K | 1 |
| Keir, ST | 1 |
| Bigner, DD | 1 |
| Hauer, J | 1 |
| Beez, T | 1 |
| Knobbe-Thomsen, CB | 1 |
| Fischer, U | 1 |
| Felsberg, J | 1 |
| Hansen, FK | 1 |
| Vibhakar, R | 1 |
| Venkatraman, S | 1 |
| Cheshier, SH | 1 |
| Reifenberger, G | 1 |
| Borkhardt, A | 1 |
| Kurz, T | 1 |
| Remke, M | 1 |
| Mitra, S | 1 |
1 other study available for ci 994 and Medulloblastoma
| Article | Year |
|---|---|
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammat
Topics: Animals; Cerebellar Neoplasms; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Inflammation; M | 2023 |