Compounds > ci 994

ci 994 and Disease Models, Animal

ci 994 has been researched along with Disease Models, Animal in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Akhtar, J; Butto, T; Cooper, A; Fend-Guella, DL; Hammer, N; Jagannath, S; Lesage, F; Radyushkin, K; Roeper, J; Schweiger, S; Strand, S; Winter, J; Zechner, U1
Fujita, Y; Matsuzaki, R; Yamashita, T; Zhang, S1
Barmo, N; Bilen, M; El Hayek, L; El-Ghandour, R; Holson, EB; Ibrahim, P; Jabre, V; Karnib, N; Khalifeh, M; Nasrallah, P; Ratan, RR; Sleiman, SF; Stephan, JS1
Dahab, GM; el-Beltagi, HM; Hagenbeek, A; Martens, AC1
el-Beltagi, HM; Hagenbeek, A; Haroun, EA; Lelieveld, P; Martens, AC1
el-Beltagi, HM; Hagenbeek, A; Haroun, EA; Martens, AC1
El-Beltagi, HM; Hagenbeek, A; Martens, AC1

Other Studies

8 other study(ies) available for ci 994 and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Inhibition of histone deacetylation rescues phenotype in a mouse model of Birk-Barel intellectual disability syndrome.
    Nature communications, 2020, 01-24, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Benzamides; Brain; Craniofacial Abnormalities; Disease Models, Animal; Female; Gene Knockdown Techniques; Genomic Imprinting; Histone Deacetylase Inhibitors; Histones; Humans; Intellectual Disability; Locus Coeruleus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Hypotonia; Mutation; Phenotype; Phenylenediamines; Potassium Channels; Up-Regulation

2020
Class I histone deacetylase (HDAC) inhibitor CI-994 promotes functional recovery following spinal cord injury.
    Cell death & disease, 2018, 05-01, Volume: 9, Issue:5

    Topics: Acetylation; Animals; Benzamides; Disease Models, Animal; Histone Deacetylase Inhibitors; Histones; Macrophages; Mice; Microglia; Motor Cortex; Neutrophils; Phenylenediamines; Spinal Cord; Spinal Cord Injuries

2018
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2019, Volume: 44, Issue:6

    Topics: Animals; Antidepressive Agents; Anxiety; Avoidance Learning; Behavior, Animal; Benzamides; Depression; Disease Models, Animal; Disease Susceptibility; Hippocampus; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histone Deacetylases; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Phenylenediamines; Resilience, Psychological; Social Behavior; Stress, Psychological

2019
Efficacy of acetyldinaline for treatment of minimal residual disease (MRD): preclinical studies in the BNML rat model for human acute myelocytic leukemia.
    Leukemia, 1993, Volume: 7, Issue:11

    Topics: Animals; Antineoplastic Agents; Benzamides; Bone Marrow Transplantation; Disease Models, Animal; Drug Screening Assays, Antitumor; Leukemia, Myeloid, Acute; Male; Phenylenediamines; Rats; Rats, Inbred BN; Recurrence

1993
Acetyldinaline: a new oral cytostatic drug with impressive differential activity against leukemic cells and normal stem cells--preclinical studies in a relevant rat model for human acute myelocytic leukemia.
    Cancer research, 1993, Jul-01, Volume: 53, Issue:13

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzamides; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Survival; Clone Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Leukemia, Myeloid, Acute; Male; Phenylenediamines; Rats; Rats, Inbred BN; Tumor Cells, Cultured

1993
In vivo development of an acetyldinaline resistant subline of the BN rat acute myelocytic leukemia (BNML).
    Leukemia, 1993, Volume: 7, Issue:8

    Topics: Animals; Antineoplastic Agents; Benzamides; Disease Models, Animal; Drug Resistance; Female; Leukemia, Myeloid, Acute; Male; Neoplasm Transplantation; Phenylenediamines; Rats; Rats, Inbred BN; Tumor Cells, Cultured

1993
Leukemia cell lines resistant to cytosine arabinoside, cyclophosphamide or daunomycin are equally sensitive to the drug acetyldinaline as the parental cell line.
    Leukemia, 2000, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzamides; Cyclophosphamide; Cytarabine; Daunorubicin; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Leukemia, Experimental; Phenylenediamines; Rats; Tumor Cells, Cultured

2000