chrysophanic acid has been researched along with Disease Models, Animal in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 7 (43.75) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Cai, B; Cheng, Y; Gao, H; Li, X; Qin, Y; Song, H; Wang, G; Wang, Y | 1 |
| Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW | 1 |
| Bhalla, S; Mehan, S; Sharma, A | 1 |
| Ding, Y; Dou, F; Duan, J; Wang, C; Wang, J; Wang, W; Wen, A; Xu, H; Zhao, X | 1 |
| Li, CQ; Xie, XJ | 1 |
| Guo, C; Piao, Y; Rao, X; Wang, Y; Yin, D | 1 |
| Kang, H; Ma, C; Ma, X; Shumin, W; Song, Y; Wang, C; Wang, J; Zhang, C; Zhang, T; Zhao, L | 1 |
| Han, NR; Jeong, HJ; Kim, HM; Moon, PD; Ryu, KJ; Yoo, MS | 1 |
| Duan, Y; Fang, Y; Gao, L; Huang, Y; Li, J; Luo, Y; Shi, W; Sun, Y; Zhao, H; Zhao, Y | 1 |
| Jee, H; Jeong, HJ; Kim, HM; Kim, HY; Yeom, JH | 1 |
| Feng, SX; Li, JS; Li, RR; Liu, XF; Qu, LB; Shu, SN; Wang, PY; Zhang, N | 1 |
| Kang, N; Liu, X; Wang, H; Wang, X; Xue, J; Yu, J; Zhang, N; Zhang, X | 1 |
| Jeong, MY; Jung, Y; Kang, J; Kim, HL; Park, J; Seok Ahn, K; Sethi, G; Um, JY; Youn, DH | 1 |
| Chang, HM; Cheng, YW; Chiou, GC; Ho, JD; Hsiao, G; Lin, CH; Lin, FL; Yen, JL | 1 |
| Fang, F; Jin, C; Kong, WJ; Wang, HJ; Wang, JB; Xiao, XH; Zhao, HP; Zhao, YL | 1 |
16 other study(ies) available for chrysophanic acid and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Chrysophanol exerts neuroprotective effects via interfering with endoplasmic reticulum stress apoptotic pathways in cell and animal models of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anthraquinones; Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cells, Cultured; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum Stress; Humans; Neurons; Neuroprotective Agents; Rats; Signal Transduction | 2022 |
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency.
Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Emodin; HaCaT Cells; Humans; Imiquimod; Inflammation; Keratinocytes; Macrophages; Mice; Psoriasis; Rheum; Skin Absorption; Swine | 2022 |
PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism in adult rats.
Topics: Animals; Anthraquinones; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Propionates; Proto-Oncogene Proteins c-akt; Rats; TOR Serine-Threonine Kinases | 2022 |
Chrysophanol ameliorates renal interstitial fibrosis by inhibiting the TGF-β/Smad signaling pathway.
Topics: Animals; Anthraquinones; Cell Line; Cell Survival; Disease Models, Animal; Epithelial Cells; Fibrosis; Humans; Kidney; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Nephritis, Interstitial; Signal Transduction; Smad Proteins; Transforming Growth Factor beta | 2020 |
Chrysophanol Protects Against Acute Heart Failure by Inhibiting JNK1/2 Pathway in Rats.
Topics: Acute Disease; Animals; Anthraquinones; Cardiotonic Agents; Disease Models, Animal; Heart Failure; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Rats | 2020 |
Chrysophanol Inhibits the Progression of Diabetic Nephropathy via Inactivation of TGF-β Pathway.
Topics: Animals; Anthraquinones; Apoptosis; Cell Cycle; Cell Proliferation; Cells, Cultured; Diabetic Nephropathies; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred C57BL; Streptozocin; Transforming Growth Factor beta | 2020 |
The effects of chrysophanol on ovalbumin (OVA)-induced chronic lung toxicology by inhibiting Th17 response.
Topics: Airway Resistance; Animals; Anthraquinones; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Mice, Inbred BALB C; Ovalbumin; Rheum; Th17 Cells | 2017 |
Regulatory effects of chrysophanol, a bioactive compound of AST2017-01 in a mouse model of 2,4-dinitrofluorobenzene-induced atopic dermatitis.
Topics: Animals; Anthraquinones; Cordyceps; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Female; Histamine; Mice, Inbred BALB C; Rumex; Skin | 2018 |
Chrysophanol attenuates nitrosative/oxidative stress injury in a mouse model of focal cerebral ischemia/reperfusion.
Topics: Animals; Anthraquinones; Apoptosis; Brain; Brain Ischemia; Caspase 3; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Nitric Oxide; Nitrosation; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tyrosine | 2018 |
The ameliorative effect of AST2017-01 in an ovalbumin-induced allergic rhinitis animal model.
Topics: Animals; Anthraquinones; Anti-Allergic Agents; Caspase 1; Cordyceps; Cytokines; Disease Models, Animal; Eosinophils; Female; Mast Cells; Mice, Inbred BALB C; Nasal Mucosa; Neutrophils; Ovalbumin; Plant Preparations; Rhinitis, Allergic; Rumex | 2019 |
Pharmacodynamics of Five Anthraquinones (Aloe-emodin, Emodin, Rhein, Chysophanol, and Physcion) and Reciprocal Pharmacokinetic Interaction in Rats with Cerebral Ischemia.
Topics: Aloe; Animals; Anthraquinones; Brain Ischemia; Disease Models, Animal; Drug Therapy, Combination; Emodin; Male; Plant Extracts; Rats; Rheum | 2019 |
Chrysophanol inhibits NALP3 inflammasome activation and ameliorates cerebral ischemia/reperfusion in mice.
Topics: Animals; Anthraquinones; Blood-Brain Barrier; Brain; Brain Ischemia; Carrier Proteins; Cerebral Infarction; Disease Models, Animal; Inflammasomes; Inflammation; Male; Mice; Microscopy, Confocal; NLR Family, Pyrin Domain-Containing 3 Protein; Permeability; Plant Extracts; Reperfusion Injury; Stroke | 2014 |
Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Animals; Anthraquinones; Cell Line; Cell Proliferation; Disease Models, Animal; Down-Regulation; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Finasteride; Male; Nuclear Receptor Coactivator 1; Organ Size; Phosphorylation; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats, Sprague-Dawley; Receptors, Androgen; Signal Transduction; Testosterone Propionate; Time Factors | 2017 |
The natural retinoprotectant chrysophanol attenuated photoreceptor cell apoptosis in an N-methyl-N-nitrosourea-induced mouse model of retinal degenaration.
Topics: Animals; Anthraquinones; Apoptosis; Disease Models, Animal; Electroretinography; Humans; Methylnitrosourea; Mice; Photoreceptor Cells; Retina; Retinal Degeneration; Tomography, Optical Coherence | 2017 |
A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract.
Topics: Administration, Oral; Animals; Anthraquinones; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Female; Kidney; Liver; Male; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rheum; Spleen; Tandem Mass Spectrometry; Tissue Distribution | 2011 |