chrysoeriol and Hemolysis

chrysoeriol has been researched along with Hemolysis* in 2 studies

Other Studies

2 other study(ies) available for chrysoeriol and Hemolysis

Article	Year
Investigation of the interaction between Chrysoeriol and xanthine oxidase using computational and in vitro approaches. International journal of biological macromolecules, 2021, Nov-01, Volume: 190 Xanthine oxidase (XO) plays a vital role in inducing hyperuricemia and increasing the level of superoxide free radicals in blood, and is proved as an important target for gout. Chrysoeriol (CHE) is a natural flavone with potent XO inhibitory activity (IC Topics: Allopurinol; Animals; Calorimetry; Cattle; Circular Dichroism; Computational Biology; Enzyme Inhibitors; Febuxostat; Flavones; Fluorescent Dyes; Hemolysis; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Structure, Secondary; Rabbits; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Xanthine Oxidase	2021
In vitro anticomplementary activity of constituents from Morinda morindoides. Journal of natural products, 1995, Volume: 58, Issue:3 In a screening program for complement classical pathway modulation, an 80% MeOH extract of the leaves of Morinda morindoides showed potent dose-dependent anticomplementary activity. Bioassay-guided chromatographic separation of the active constituents led to the isolation of ten flavonoids of which two were aglycones. The compounds were tested in vitro for their putative complement-inhibiting properties on the classical (CP) and the alternative (AP) pathways of the complement system. The results indicated that quercetin [1], quercetin 3-O-rhamnoside (quercitrin) [5], and quercetin 3-O-rutinoside (rutin) [7] showed similar anticomplementary activities (inhibition) on the CP of complement. A mixture of two kaempferol triglycosides isolated and denoted as M(015), also had a good inhibitory effect. The effects of these compounds were dose-dependent for this pathway. On the AP of complement, quercetin [1] and M(015) had, respectively, more pronounced inhibitory and activatory effects than the other tested flavonoids, but their effects were not dose-dependent for this pathway. The other isolated flavonoids showed weak effects or were inactive for both pathways. Topics: Animals; Complement Inactivator Proteins; Complement Pathway, Alternative; Complement Pathway, Classical; Flavonoids; Guinea Pigs; Hemolysis; Humans; In Vitro Techniques; Plant Extracts; Plant Leaves; Plants, Medicinal; Rabbits; Sheep	1995

Article

Year

Investigation of the interaction between Chrysoeriol and xanthine oxidase using computational and in vitro approaches.

International journal of biological macromolecules, 2021, Nov-01, Volume: 190

Xanthine oxidase (XO) plays a vital role in inducing hyperuricemia and increasing the level of superoxide free radicals in blood, and is proved as an important target for gout. Chrysoeriol (CHE) is a natural flavone with potent XO inhibitory activity (IC

Topics: Allopurinol; Animals; Calorimetry; Cattle; Circular Dichroism; Computational Biology; Enzyme Inhibitors; Febuxostat; Flavones; Fluorescent Dyes; Hemolysis; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Structure, Secondary; Rabbits; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Xanthine Oxidase

2021

In vitro anticomplementary activity of constituents from Morinda morindoides.

Journal of natural products, 1995, Volume: 58, Issue:3

In a screening program for complement classical pathway modulation, an 80% MeOH extract of the leaves of Morinda morindoides showed potent dose-dependent anticomplementary activity. Bioassay-guided chromatographic separation of the active constituents led to the isolation of ten flavonoids of which two were aglycones. The compounds were tested in vitro for their putative complement-inhibiting properties on the classical (CP) and the alternative (AP) pathways of the complement system. The results indicated that quercetin [1], quercetin 3-O-rhamnoside (quercitrin) [5], and quercetin 3-O-rutinoside (rutin) [7] showed similar anticomplementary activities (inhibition) on the CP of complement. A mixture of two kaempferol triglycosides isolated and denoted as M(015), also had a good inhibitory effect. The effects of these compounds were dose-dependent for this pathway. On the AP of complement, quercetin [1] and M(015) had, respectively, more pronounced inhibitory and activatory effects than the other tested flavonoids, but their effects were not dose-dependent for this pathway. The other isolated flavonoids showed weak effects or were inactive for both pathways.

Topics: Animals; Complement Inactivator Proteins; Complement Pathway, Alternative; Complement Pathway, Classical; Flavonoids; Guinea Pigs; Hemolysis; Humans; In Vitro Techniques; Plant Extracts; Plant Leaves; Plants, Medicinal; Rabbits; Sheep

1995