chrysin and Osteoporosis--Postmenopausal

Evidences are beginning to accrue that flavonoids, particularly phytoestrogens, could have beneficial effects against several age-related diseases linked to estrogen deficiency including postmenopausal osteoporosis.. In this study, the effect of chrysin on selected bone-remodeling markers in ovariectomized rats and its estrogen-like activity. This study demonstrated that chrysin exhibits potential antiosteoporotic effects against bone loss in OVX rats through enhanced bone mineral contents and preventing excessive elevation of bone-remodeling markers and bone-resorbing cytokine.

Topics: Animals; Biomarkers; Bone Density Conservation Agents; Bone Remodeling; Computer Simulation; Estrogens; Female; Flavonoids; Humans; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Wistar