chondroitin-sulfates and Prognathism

The purpose of this study was to compare retrospectively postoperative differences in maxillary stability after Le Fort I osteotomy and fixation with an unsintered hydroxyapatite (u-HA)/poly-l-lactic acid (PLLA) plate with or without self-setting α-tricalcium phosphate (Biopex(®)) as interpositional material. Subjects comprised 45 patients diagnosed with mandibular prognathism with maxillary retrognathism and mandibular prognathism with bimaxillary asymmetry. All patients underwent Le Fort I osteotomy and bilateral sagittal split ramus osteotomy with fixation by uHA/PLLA plates. Patients were divided into 4 groups consisting of 9 maxillary impaction cases with Biopex(®) (group 1) to fill the gap between the bone segments, 14 maxillary advancement cases with Biopex(®) (group 2), 8 maxillary impaction cases without Biopex(®) (group 3) and 14 maxillary advancement cases without Biopex(®) (group 4). Changes in cepahalometric parameters at time intervals (1, 3 and 12 months) between the groups were compared. Results showed that stability did not depend on the use or otherwise of Biopex(®).

Topics: Absorbable Implants; Adolescent; Adult; Biocompatible Materials; Bone Cements; Bone Plates; Calcium Phosphates; Cephalometry; Chondroitin Sulfates; Durapatite; Facial Asymmetry; Female; Follow-Up Studies; Humans; Hydroxyapatites; Incisor; Jaw Fixation Techniques; Male; Mandible; Maxilla; Middle Aged; Nasal Bone; Osteotomy, Le Fort; Osteotomy, Sagittal Split Ramus; Polyesters; Prognathism; Retrospective Studies; Sella Turcica; Succinates; Young Adult