chondroitin-sulfates and Iris-Diseases

We described a technique to perform anterior synechiolysis with a healon needle and Viscoat® ophthalmic viscosurgical devices (OVDs) through anterior lamellar dissection in penetrating keratoplasty.. OVDs were gently injected between iridocorneal adhesions with a healon needle to make a blunt dissection after anterior lamellar corneal dissection. Anterior synechiolysis at 360 degrees was completed with a healon needle and OVDs. Subsequently, the deep corneal lamella was cut with right and left Troutman-Katzin corneal scissors. 24 interrupted sutures were made with 10-0 nylon suture to implant the donor cornea.. In two eyes from two patients, with corneal opacity and nearly total anterior synechiae, clear grafts and relatively deep anterior chambers were achieved. Penetrating keratoplasty with anterior synechiolysis was thus successful with a healon needle and OVDs through lamellar dissection.. Anterior synechiolysis with a healon needle and OVDs through lamellar dissection is a safe and efficient technique for keratoplasty in patients with corneal opacity with anterior synechiae.

Topics: Aged; Aged, 80 and over; Chondroitin Sulfates; Cornea; Corneal Opacity; Drug Combinations; Female; Humans; Hyaluronic Acid; Iris Diseases; Keratoplasty, Penetrating; Suture Techniques; Tissue Adhesions; Viscosupplements

To evaluate the incidence of IFIS in male patients whith alfa 1-AB treatment for benign prostatic hyperplasia (BPH) who underwent cataract surgery and also the pre and intraoperatory management and IFIS profilaxy.. Iasi "Sf Spiridon" Emergency Hospital and "Oftaprof" private practice. Observational retrospective study that took place over a period of 2 years (july 2009-july 2011) and reviewed 2484 eyes that underwent cataract surgery. A number of 1199 eyes were from 1049 male patients.. Out of the 1049 male patients, 139 (13,25%) underwent treatment for BHP using the medication as follows: 119 used tamsulosin (85,6%); 18 used doxazosin, (12,94%); 2 used alfuzosin (1,43%). Out of the 139 men, 32 (23,02%) showed IFIS but only the ones treated with tamsulosin. After introducing a surgical protocol that comprised of the use of large amounts of vascoelastic material (Viscoat), intracamerular fenilefrin (Mezaton), the use of iris retractors and low faco parameters the incidence and severity of IFIS was significantly reduced.. Correct evauation before surgery is necessary in order to anticipate the condition as its frequency and severity can be reduced by a proactive behavior which demands experience and adequate endowment.

Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Aged; Cataract Extraction; Chondroitin Sulfates; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hyaluronic Acid; Incidence; Injections, Intraocular; Intraoperative Care; Iris Diseases; Male; Phenylephrine; Preoperative Care; Prostatic Hyperplasia; Pupil; Retrospective Studies; Romania; Sulfonamides; Syndrome; Tamsulosin; Treatment Outcome

To introduce a case of iridoschisis patient who underwent cataract surgery successfully without pupil device.. A 64-year-old female who showed iridoschisis of her both eyes underwent cataract operation at her right eye without a pupillary device. The preoperative and postoperative ophthalmologic examinations including visual acuity, intraocular pressure, reaction of anterior chamber, and degree of damage on iris was evaluated respectively.. Cataract surgery was performed under topical anesthesia through a clear corneal incision. Iris fibrils were held in place by ophthalmic viscosurgical device (OVD, sodium hyaluronate 3%-sodium chondroitin sulfate 4%, Viscoat) that was injected into the anterior chamber. A small capsulorrhexis was made and the nucleus was delivered with low-power phacoemulsification, most of which was performed under the anterior capsule. The iris came into contact with the OVDs only and received no mechanical trauma. There were no intraoperative complications such as tear of the iris, hyphema, loss of mydriasis, or rupture of the posterior lens capsule. The edema of corneal stroma and inflammation of anterior chamber was shown at immediate-postoperative period, but completely subsided 2 weeks later. The visual acuity showed improvement from 20/400 to 20/30.. In iridoschisis patients, there is a risk of aspiration of iris fibers during cataract surgery. With adequate use of OVD and careful modulation of surgical devices, cataract surgery was successfully performed without using extra pupil-supporting device.

Topics: Anesthesia, Local; Cataract; Chondroitin; Chondroitin Sulfates; Drug Combinations; Female; Humans; Hyaluronic Acid; Iris Diseases; Lens Implantation, Intraocular; Middle Aged; Phacoemulsification; Visual Acuity

I describe a technique using ophthalmic viscosurgical devices to perform cataract surgery in patients taking tamsulosin (Flomax). The 6-step method uses a combination variant of the soft-shell and ultimate soft-shell techniques and involves adjustments to flow parameters. It achieves satisfactory iris stability and permits uneventful surgery.

Topics: Acetates; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Anterior Chamber; Chondroitin; Chondroitin Sulfates; Drug Combinations; Humans; Hyaluronic Acid; Intraoperative Complications; Iris Diseases; Lens Implantation, Intraocular; Minerals; Phacoemulsification; Pupil; Sodium Chloride; Sulfonamides; Syndrome; Tamsulosin

The iris of patients with exfoliation syndrome and senile cataracts were studied with a polarization microscope as well as histochemically. Amorphous substance stained by pH 1.0 alcian blue was observed in exfoliation syndrome on the posterior surface of the iris. This layer was thicker in exfoliation syndrome than in senile cataracts. The major component of this layer was verified as chondroitin sulphate and the minor one as hyaluronic acid. Polarization microscopic study demonstrated the presence of more sulphated glycosaminoglycans in exfoliation syndrome than in senile cataracts. Abnormal metabolism of glycosaminoglycans is indicated in the iris of exfoliation syndrome.

Topics: Aged; Cataract; Chondroitin Sulfates; Female; Glycosaminoglycans; Histocytochemistry; Humans; Hyaluronic Acid; Iris; Iris Diseases; Male; Microscopy, Polarization; Middle Aged; Syndrome