chondroitin-sulfates has been researched along with Hyperammonemia* in 1 studies
1 other study(ies) available for chondroitin-sulfates and Hyperammonemia
| Article | Year |
|---|---|
Poly(ornithine)-based self-assembling drug for recovery of hyperammonemia and damage in acute liver injury.
Oligo-peptides, including monomeric amino acids, have received much attention as bioactive molecules and drugs. One of the biggest problems of these compounds, however, is their very short bioavailability due to instant metabolism and rapid excretion. To solve this problem, we newly designed a poly(ethylene glycol) (PEG)-block-polypeptide self-assembling based drug for the treatment of acute liver injury. Here, PEG-block-poly(L-Ornithine) (PEG-b-POrn) was synthesized via a ring opening polymerization, and a nano-sized polyion self-assembling complex (Nano Topics: Acetaminophen; Ammonia; Animals; Cattle; Cell Survival; Chemical and Drug Induced Liver Injury; Chondroitin Sulfates; Disease Models, Animal; Drug Delivery Systems; Endothelial Cells; Hyperammonemia; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nanoparticles; Ornithine; RAW 264.7 Cells | 2019 |