chondroitin-sulfates and Cachexia

chondroitin-sulfates has been researched along with Cachexia* in 1 studies

Other Studies

1 other study(ies) available for chondroitin-sulfates and Cachexia

Article	Year
Isolation, characterization, and distribution of a 24-kDa proteoglycan in the urine of cachectic cancer and AIDS patients. Biochemical and biophysical research communications, 1999, Jan-27, Volume: 254, Issue:3 Substantial weight loss in individuals with AIDS or cancer is associated with a poor prognosis and increased mortality. We have isolated and partially characterized a proteoglycan (named azaftig) from the urine of a cancer patient experiencing weight loss. Furthermore, we have raised a polyclonal antibody to azaftig in rabbits and developed a procedure to measure the level of this proteoglycan in urine by Western blot. We report the presence of azaftig in the urine of cancer and AIDS patients experiencing weight loss, but not in the control or weight-stable subjects. The azaftig-like immunoreactivity was present in 69.2% (9/13) of patients with weight loss, but only in 27.0% (3/11) of weight-stable cancer or AIDS patients and none of the control subjects (n = 8). Topics: Adult; Blotting, Western; Cachexia; Case-Control Studies; Chondroitin Sulfates; HIV Wasting Syndrome; Humans; Neoplasms; Proteoglycans	1999

Article

Year

Isolation, characterization, and distribution of a 24-kDa proteoglycan in the urine of cachectic cancer and AIDS patients.

Biochemical and biophysical research communications, 1999, Jan-27, Volume: 254, Issue:3

Substantial weight loss in individuals with AIDS or cancer is associated with a poor prognosis and increased mortality. We have isolated and partially characterized a proteoglycan (named azaftig) from the urine of a cancer patient experiencing weight loss. Furthermore, we have raised a polyclonal antibody to azaftig in rabbits and developed a procedure to measure the level of this proteoglycan in urine by Western blot. We report the presence of azaftig in the urine of cancer and AIDS patients experiencing weight loss, but not in the control or weight-stable subjects. The azaftig-like immunoreactivity was present in 69.2% (9/13) of patients with weight loss, but only in 27.0% (3/11) of weight-stable cancer or AIDS patients and none of the control subjects (n = 8).

Topics: Adult; Blotting, Western; Cachexia; Case-Control Studies; Chondroitin Sulfates; HIV Wasting Syndrome; Humans; Neoplasms; Proteoglycans

1999