choline has been researched along with Vitamin B 12 Deficiency in 26 studies
Vitamin B 12 Deficiency: A nutritional condition produced by a deficiency of VITAMIN B 12 in the diet, characterized by megaloblastic anemia. Since vitamin B 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin B 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. (From Cecil Textbook of Medicine, 19th ed, p848)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adequate choline intake during pregnancy is essential for proper fetal development." | 8.91 | [Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy]. ( Drews, K, 2015) |
| "Choline needs are increased in pregnancy." | 7.79 | Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants. ( Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT, 2013) |
| "Adequate choline intake during pregnancy is essential for proper fetal development." | 4.91 | [Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy]. ( Drews, K, 2015) |
| "Choline needs are increased in pregnancy." | 3.79 | Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants. ( Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT, 2013) |
| "Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance." | 1.39 | Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. ( Bjelland, I; Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, DA; Tell, GS; Ueland, PM; Vollset, SE, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (65.38) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alsayed, R | 1 |
| Al Quobaili, F | 1 |
| Srour, S | 1 |
| Geisel, J | 1 |
| Obeid, R | 1 |
| Wu, BT | 1 |
| Innis, SM | 1 |
| Mulder, KA | 1 |
| Dyer, RA | 1 |
| King, DJ | 1 |
| Ekici, F | 1 |
| Tekbas, G | 1 |
| Hattapoğlu, S | 1 |
| Yaramış, A | 1 |
| Önder, H | 1 |
| Bilici, A | 1 |
| Drews, K | 1 |
| Nurk, E | 1 |
| Refsum, H | 1 |
| Bjelland, I | 1 |
| Drevon, CA | 1 |
| Tell, GS | 1 |
| Ueland, PM | 1 |
| Vollset, SE | 1 |
| Engedal, K | 1 |
| Nygaard, HA | 1 |
| Smith, DA | 1 |
| Bressenot, A | 1 |
| Pooya, S | 1 |
| Bossenmeyer-Pourie, C | 1 |
| Gauchotte, G | 1 |
| Germain, A | 1 |
| Chevaux, JB | 1 |
| Coste, F | 1 |
| Vignaud, JM | 1 |
| Guéant, JL | 2 |
| Peyrin-Biroulet, L | 1 |
| Brunaud, L | 1 |
| Alberto, JM | 1 |
| Ayav, A | 1 |
| Gérard, P | 1 |
| Namour, F | 1 |
| Antunes, L | 1 |
| Braun, M | 1 |
| Bronowicki, JP | 1 |
| Bresler, L | 1 |
| STEKOL, JA | 2 |
| WEISS, S | 2 |
| SMITH, P | 1 |
| WEISS, K | 1 |
| FIRTH, J | 1 |
| MISTRY, SP | 1 |
| JAMES, MF | 1 |
| JOHNSON, BC | 2 |
| YOUNG, RJ | 1 |
| NORRIS, LC | 1 |
| HEUSER, GF | 1 |
| ANDERSON, EI | 1 |
| HSU, PT | 1 |
| WATJEN, A | 1 |
| TOURY, R | 1 |
| LEVY, M | 1 |
| CHANG, I | 1 |
| VERLY, WG | 1 |
| CATHEY, WJ | 1 |
| Vitale, JJ | 1 |
| Hegsted, DM | 1 |
| Park, CS | 1 |
| Choi, CB | 1 |
| Baik, MG | 1 |
| Keller, WL | 1 |
| Glade, MJ | 1 |
| Asoklis, K | 1 |
| Asoklis, R | 1 |
| Newberne, PM | 3 |
| Rogers, AE | 1 |
| Blair, R | 1 |
| Newsome, F | 1 |
| Buehring, KU | 1 |
| Batra, KK | 1 |
| Stokstad, EL | 1 |
| Keshavarz, K | 1 |
| Fuller, HL | 1 |
| Edelstein, S | 1 |
| Guggenheim, K | 1 |
| Legrand, J | 1 |
| Woodard, JC | 1 |
| Young, VR | 1 |
4 reviews available for choline and Vitamin B 12 Deficiency
| Article | Year |
|---|---|
[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy].
Topics: Choline; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Maternal Nutritiona | 2015 |
Effects of vitamin B12 and folate deficiencies on DNA methylation and carcinogenesis in rat liver.
Topics: Animals; Carcinogens; Choline; Choline Deficiency; Diet; DNA Methylation; Folic Acid Deficiency; Gas | 2003 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic | 1986 |
Involvement of water-soluble vitamins in diseases of swine.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Biotin; Choline; Choline Deficiency; Folic Acid; F | 1985 |
22 other studies available for choline and Vitamin B 12 Deficiency
| Article | Year |
|---|---|
Elevated dimethylglycine in blood of children with congenital heart defects and their mothers.
Topics: Adult; Betaine; Betaine-Homocysteine S-Methyltransferase; Biomarkers; Child, Preschool; Choline; Chr | 2013 |
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Aci | 2013 |
Brain MRI and MR Spectroscopy Findings in Children with Nutritional Vitamin B12 Deficiency.
Topics: Aspartic Acid; Biomarkers; Brain; Child, Preschool; Choline; Creatine; Female; Humans; Infant; Magne | 2016 |
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Cognitive Dysfunction; Cohort Studies | 2013 |
Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.
Topics: Alkaline Phosphatase; Animal Feed; Animals; Apoptosis; beta Catenin; Cadherins; Caspase 3; Cell Diff | 2013 |
The synthesis of choline and creatine in rats under various dietary conditions.
Topics: Animals; Choline; Creatine; Creatinine; Diet; Folic Acid; Folic Acid Deficiency; Rats; Vitamin B 12 | 1953 |
Vitamin B12 and transmethylation in the baby pig.
Topics: Animals; Choline; Corrinoids; Methionine; Swine; Vitamin B 12; Vitamin B 12 Deficiency | 1954 |
The utilization by vitamin B12-deficient chicks of monomethylaminoethanol, homocystine and betaine as precursors of choline and methionine.
Topics: Amino Acids; Amino Alcohols; Animals; Betaine; Chickens; Choline; Homocystine; Methionine; Vitamin B | 1954 |
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12 | 1957 |
[Study of the oxidation of fatty acids in the kidney of young rats with steatosis induced by a low-protein, high-lipid diet deficient in choline and vitamin B12].
Topics: Animals; Choline; Choline Deficiency; Diet; Fats; Fatty Acids; Kidney; Liver Diseases; Nutrition Ass | 1962 |
The effect of vitamin B12 on some aspects of glycine metabolism.
Topics: Biochemical Phenomena; Choline; Glycine; Serine; Vitamin B 12; Vitamin B 12 Deficiency | 1955 |
The influence of vitamin B12 on the biosynthesis of the methyl group of choline from methanol.
Topics: Choline; Corrinoids; Ethanol; Methanol; Vitamin B 12; Vitamin B 12 Deficiency | 1955 |
Vitamin B12 deficiency in the rat: effect on serum folate and liver formiminotransferase activity.
Topics: Aldehyde-Lyases; Animals; Biological Assay; Choline; Folic Acid; Glutamates; Liver; Male; Methionine | 1967 |
Modulation of expression of fos and Ha-ras oncogenes and ornithine decarboxylase activity in mammary gland and liver of young female rats by the absence of dietary lipotropes.
Topics: Animals; Choline; Choline Deficiency; Diet; Female; Folic Acid; Folic Acid Deficiency; Gene Expressi | 1994 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Fem | 1999 |
[Treatment of vitamin B 12 deficiency].
Topics: Arginine; Aspartic Acid; Choline; Drug Combinations; Folic Acid; Folic Acid Deficiency; Humans; Inje | 1977 |
The effect of methionine on folic acid and histidine metabolism in perfused rat liver.
Topics: Animals; Betaine; Carbon Dioxide; Carbon Isotopes; Choline; Deficiency Diseases; Drug Synergism; Eth | 1972 |
Relationship of arginine and methionine to creatine formation in chicks.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Ch | 1971 |
Effects of sulfur-amino acids and choline on vitamin B 12 -deficient rats.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Choline; Cysteine; Drug Synergism; | 1971 |
[Activity in vitro of oxidase of fatty acids; effect of estrogens].
Topics: Animals; Castration; Choline; Choline Deficiency; Estradiol; Fatty Acids; Female; Liver; Ovary; Oxyg | 1967 |
Relation of vitamin B12 and one-carbon metabolism to hydrocephalus in the rat.
Topics: Animals; Animals, Newborn; Carbon; Choline; Diet; Folic Acid; Folic Acid Antagonists; Hydrocephalus; | 1966 |
Effect of diets marginal in methionine and choline with and without vitamin B 12 on rat liver and kidney.
Topics: Animals; Choline; Choline Deficiency; Deficiency Diseases; Kidney Diseases; Liver Diseases; Methioni | 1966 |