choline has been researched along with Tourette Syndrome in 11 studies
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)." | 7.68 | Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992) |
| " Alterations in cholinergic function may play a role in the pathophysiology of idiopathic spasmodic torticollis (ST) and Gilles de la Tourette's syndrome (GTS)." | 7.68 | Red cell choline in spasmodic torticollis and in a monozygotic twin pair with Tourette's syndrome. ( Gauthier, S; Kiely, ME; Lal, S; Vasavan Nair, NP; Waserman, J; Wood, PL, 1990) |
| "Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)." | 3.68 | Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992) |
| " Alterations in cholinergic function may play a role in the pathophysiology of idiopathic spasmodic torticollis (ST) and Gilles de la Tourette's syndrome (GTS)." | 3.68 | Red cell choline in spasmodic torticollis and in a monozygotic twin pair with Tourette's syndrome. ( Gauthier, S; Kiely, ME; Lal, S; Vasavan Nair, NP; Waserman, J; Wood, PL, 1990) |
| "Huntington's chorea, ataxias, Tourette's syndrome, schizophrenia, affective illness, and senile dementia of the Alzheimer type, has been implicated with a general underactivity of central cholinergic mechanisms." | 2.36 | The use of cholinergic precursors in neuropsychiatric diseases. ( Davis, KL; Rosenberg, GS, 1982) |
| "Patients with Tourette's disorder demonstrated a reduction in N-acetylaspartate and choline in the left putamen, along with reduced levels of creatine bilaterally in the putamen." | 1.33 | Brain magnetic resonance spectroscopy in Tourette's disorder. ( DeVito, TJ; Drost, DJ; McKinlay, BD; Neufeld, RW; Nicolson, R; Pavlosky, W; Rajakumar, N; Williamson, PC, 2005) |
| "Because patients with Tourette's syndrome have been reported to have increased red blood cell choline levels, choline levels were examined in relation to treatment response." | 1.27 | Blood choline and response to clonazepam and haloperidol in Tourette's syndrome. ( Hanin, I; Kopp, U; Merikangas, JR; Merikangas, KR, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, S | 1 |
| Cath, DC | 1 |
| van den Heuvel, OA | 1 |
| van der Werf, YD | 1 |
| Schöls, C | 1 |
| Veltman, DJ | 1 |
| Pouwels, PJW | 1 |
| DeVito, TJ | 1 |
| Drost, DJ | 1 |
| Pavlosky, W | 1 |
| Neufeld, RW | 1 |
| Rajakumar, N | 1 |
| McKinlay, BD | 1 |
| Williamson, PC | 1 |
| Nicolson, R | 1 |
| Rosenberg, GS | 2 |
| Davis, KL | 2 |
| Stahl, SM | 1 |
| Berger, PA | 1 |
| Comings, DE | 1 |
| Gursey, BT | 1 |
| Avelino, E | 1 |
| Kopp, U | 4 |
| Hanin, I | 4 |
| Barbeau, A | 1 |
| Merikangas, JR | 2 |
| Merikangas, KR | 2 |
| Sallee, FR | 1 |
| Lal, S | 1 |
| Gauthier, S | 1 |
| Wood, PL | 1 |
| Kiely, ME | 1 |
| Waserman, J | 1 |
| Vasavan Nair, NP | 1 |
2 reviews available for choline and Tourette Syndrome
| Article | Year |
|---|---|
The use of cholinergic precursors in neuropsychiatric diseases.
Topics: Acetylcholine; Alzheimer Disease; Animals; Bipolar Disorder; Brain; Cerebellar Ataxia; Choline; Huma | 1982 |
Emerging treatments: replacement therapy with choline or lecithin in neurological diseases.
Topics: Animals; Choline; Dyskinesia, Drug-Induced; Friedreich Ataxia; Humans; Huntington Disease; Nervous S | 1978 |
9 other studies available for choline and Tourette Syndrome
| Article | Year |
|---|---|
Abnormalities in metabolite concentrations in tourette's disorder and obsessive-compulsive disorder-A proton magnetic resonance spectroscopy study.
Topics: Adult; Choline; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Obsessiv | 2017 |
Brain magnetic resonance spectroscopy in Tourette's disorder.
Topics: Adolescent; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Corpus Striatum; Creatine; Dominanc | 2005 |
Physostigmine in Gilles de la Tourette's syndrome.
Topics: Adolescent; Adult; Choline; Humans; Male; Phosphatidylcholines; Physostigmine; Tourette Syndrome | 1980 |
Red blood cell choline in Tourette syndrome.
Topics: Adolescent; Adult; Child; Choline; Erythrocytes; Female; Humans; Male; Tourette Syndrome | 1982 |
Precursors of acetylcholine: considerations underlying their use in Tourette syndrome.
Topics: Acetylcholine; Animals; Brain; Choline; Diet; Humans; Movement Disorders; Outcome and Process Assess | 1982 |
Red-cell choline and Gilles de la Tourette syndrome.
Topics: Choline; Erythrocytes; Humans; Tourette Syndrome | 1979 |
Controlled study of erythrocyte choline in Tourette syndrome.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Choline; Drug Therapy, Combination | 1992 |
Red cell choline in spasmodic torticollis and in a monozygotic twin pair with Tourette's syndrome.
Topics: Adult; Choline; Diseases in Twins; Erythrocytes; Female; Humans; Male; Middle Aged; Reference Values | 1990 |
Blood choline and response to clonazepam and haloperidol in Tourette's syndrome.
Topics: Adolescent; Adult; Benzodiazepinones; Child; Choline; Clonazepam; Erythrocytes; Female; Haloperidol; | 1985 |