choline has been researched along with Thrombosis in 20 studies
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
Excerpt | Relevance | Reference |
---|---|---|
"Gut microbes influence cardiovascular disease and thrombosis risks through the production of trimethylamine N-oxide (TMAO)." | 5.27 | Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. ( DiDonato, JA; Fischbach, MA; Guo, CJ; Haag, B; Hazen, SL; Jia, X; Kirsop, J; Lang, JM; Lusis, AJ; Rey, FE; Romano, KA; Skye, SM; Tang, WHW; Wang, Z; Zhu, W, 2018) |
"Endothelial TF contributes to TMAO-related arterial thrombosis potential, and can be specifically blocked by targeted non-lethal inhibition of gut microbial choline TMA-lyase." | 4.12 | Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis. ( Buffa, JA; DiDonato, JA; Friebel, J; Haghikia, A; Hazen, SL; Kirchhofer, D; Landmesser, U; Li, L; Li, XS; Lüscher, TF; Mach, F; Matter, CM; Räber, L; Rauch, U; Sangwan, N; Tang, WHW; Tizian, C; Wang, Z; Witkowski, M, 2022) |
" Furthermore, unlike chronic dietary choline, TML supplementation in mice failed to elevate plasma TMAO or heighten thrombosis potential in vivo." | 3.88 | Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. ( Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y, 2018) |
"Phenylacetylglutamine, for example, was recently shown to promote adverse cardiovascular phenotypes in the host via interaction with multiple ARs (adrenergic receptors)-a class of key receptors that regulate cardiovascular homeostasis." | 2.66 | Gut Microbiota and Cardiovascular Disease. ( Hazen, SL; Weeks, TL; Witkowski, M, 2020) |
"18 F-choline PET/CT was performed for initial staging and displayed several intense foci uptake of sternum and thoracic vertebrae, suggestive of bone metastasis." | 1.91 | A False-Positive Bone Oligometastatic Prostate Cancer in 18 F-Choline PET/CT : Be Aware of Chronic Vascular Pitfalls. ( Kryza, D; Larrouquere, L; Mognetti, T; Moreau, A; Pretet, V, 2023) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (40.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 8 (40.00) | 24.3611 |
2020's | 4 (20.00) | 2.80 |
Authors | Studies |
---|---|
Tu, R | 1 |
Xia, J | 1 |
Pretet, V | 1 |
Moreau, A | 1 |
Larrouquere, L | 1 |
Mognetti, T | 1 |
Kryza, D | 1 |
Witkowski, M | 3 |
Weeks, TL | 1 |
Hazen, SL | 8 |
Friebel, J | 1 |
Buffa, JA | 4 |
Li, XS | 2 |
Wang, Z | 7 |
Sangwan, N | 1 |
Li, L | 4 |
DiDonato, JA | 5 |
Tizian, C | 1 |
Haghikia, A | 1 |
Kirchhofer, D | 1 |
Mach, F | 1 |
Räber, L | 1 |
Matter, CM | 1 |
Tang, WHW | 5 |
Landmesser, U | 1 |
Lüscher, TF | 2 |
Rauch, U | 1 |
Zhu, W | 5 |
Marosfoi, M | 1 |
Clarencon, F | 1 |
Langan, ET | 1 |
King, RM | 1 |
Brooks, OW | 1 |
Tamura, T | 1 |
Wainwright, JM | 1 |
Gounis, MJ | 1 |
Vedantham, S | 1 |
Puri, AS | 1 |
Cajka, T | 1 |
Nemet, I | 1 |
Hurd, AG | 2 |
Gu, X | 2 |
Skye, SM | 3 |
Roberts, AB | 2 |
Wu, Y | 2 |
Shahen, CJ | 1 |
Wagner, MA | 1 |
Hartiala, JA | 1 |
Kerby, RL | 1 |
Romano, KA | 2 |
Han, Y | 1 |
Obeid, S | 1 |
Allayee, H | 2 |
Rey, FE | 2 |
Fiehn, O | 1 |
Gupta, N | 2 |
Cody, DB | 1 |
Levison, BS | 1 |
Barrington, WT | 1 |
Russell, MW | 1 |
Reed, JM | 1 |
Duzan, A | 1 |
Lang, JM | 2 |
Fu, X | 2 |
Myers, AJ | 1 |
Rachakonda, S | 1 |
Brown, JM | 3 |
Gogonea, V | 1 |
Lusis, AJ | 4 |
Garcia-Garcia, JC | 1 |
Guo, CJ | 1 |
Jia, X | 2 |
Kirsop, J | 1 |
Haag, B | 1 |
Fischbach, MA | 1 |
Shih, DM | 1 |
Schugar, RC | 1 |
Meng, Y | 1 |
Miikeda, A | 1 |
Zieger, M | 1 |
Lee, R | 1 |
Graham, M | 1 |
Cantor, RM | 1 |
Mueller, C | 1 |
Gregory, JC | 1 |
Org, E | 1 |
Mehrabian, M | 1 |
Sartor, RB | 1 |
McIntyre, TM | 1 |
Silverstein, RL | 1 |
Tilg, H | 1 |
RENAUD, S | 2 |
ALLARD, C | 1 |
MORELLI, AC | 1 |
Durrani, AA | 1 |
Hayward, JA | 1 |
Chapman, D | 1 |
Perry, TL | 1 |
Hansen, S | 1 |
Love, DL | 1 |
Crawford, LE | 1 |
Tischler, B | 1 |
Vittori, C | 1 |
Borri, P | 1 |
Bianchi, V | 1 |
Kuznik, BI | 1 |
Mishchenko, VP | 1 |
Thomas, HM | 1 |
Williams, WL | 1 |
Clower, BR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
"Plant-Based Meat vs Animal Red Meat: a Randomized Cross-over Trial"[NCT04510324] | 41 participants (Actual) | Interventional | 2020-11-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for choline and Thrombosis
Article | Year |
---|---|
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO.
Topics: Choline; Cognitive Dysfunction; Gastrointestinal Microbiome; Humans; Inflammation; Stroke; Thrombosi | 2024 |
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease | 2020 |
[Role of the heart and vessels in regulating blood coagulation and fibrinolysis].
Topics: Animals; Antifibrinolytic Agents; Blood Coagulation; Blood Platelets; Blood Pressure; Blood Vessels; | 1973 |
2 trials available for choline and Thrombosis
Article | Year |
---|---|
Gut Microbe-Generated Trimethylamine
Topics: Adult; Aspirin; Choline; Dietary Fats; Female; Gastrointestinal Microbiome; Humans; Male; Methylamin | 2017 |
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
Topics: Adult; Animals; Bacterial Proteins; Choline; Clostridium; Fecal Microbiota Transplantation; Female; | 2018 |
15 other studies available for choline and Thrombosis
Article | Year |
---|---|
A False-Positive Bone Oligometastatic Prostate Cancer in 18 F-Choline PET/CT : Be Aware of Chronic Vascular Pitfalls.
Topics: Aged; Choline; Humans; Male; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; | 2023 |
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis.
Topics: Animals; Choline; Endothelial Cells; Humans; Lyases; Methylamines; Mice; Thromboplastin; Thrombosis | 2022 |
Acute thrombus formation on phosphorilcholine surface modified flow diverters.
Topics: Angioplasty; Animals; Choline; Female; Intracranial Aneurysm; Pancreatic Elastase; Phosphorus; Rabbi | 2018 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Mo | 2018 |
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Topics: Animals; Bacteria; Choline; Diet; Gastrointestinal Microbiome; Hexanols; Mice, Inbred C57BL; Oxidore | 2018 |
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mic | 2019 |
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Topics: Animals; Blood Platelets; Calcium; Carotid Artery Injuries; Cecum; Chlorides; Choline; Diet; Female; | 2016 |
A Gut Feeling about Thrombosis.
Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Mice; Plasmalogens; Risk Factor | 2016 |
DIETARY FATS, VITAMINS AND BILE ACIDS IN THE PRODUCTION OF THROMBOSIS AND HYPERLIPEMIA IN RATS.
Topics: Bile Acids and Salts; Blood Chemical Analysis; Butter; Cholesterol; Choline; Coronary Disease; Dieta | 1963 |
[ELEVATION OF THE DEPRESSED THROMBOLYTIC ACTIVITY, IN ARTERIOSCLEROTICS SUBJECTED TO PROLONGED ORAL ANTICOAGULANT THERAPY, USING A DERIVATIVE OF NICOTINIC ACID].
Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Arteriosclerosis; Blood Coagulation Tests; Cholin | 1963 |
Biomembranes as models for polymer surfaces. II. The syntheses of reactive species for covalent coupling of phosphorylcholine to polymer surfaces.
Topics: Biocompatible Materials; Blood Cells; Cell Membrane; Choline; Humans; Membranes, Artificial; Phospho | 1986 |
Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Choline; Cys | 1968 |
[On the comparative results of the use of Clarisco in peripheral vascular diseases].
Topics: Aged; Arteriosclerosis Obliterans; Choline; Coronary Disease; Folic Acid; Gangrene; Heparin; Humans; | 1970 |
Cardiac lesions in C mice. Result of choline-deficient and choline-supplemented diets.
Topics: Animals; Calcinosis; Choline; Choline Deficiency; Coronary Vessels; Fibroblasts; Heart Atria; Heart | 1968 |
Prevention by methionine feeding of atherosclerosis and thrombosis in hyperlipemic rats.
Topics: Animals; Arteriosclerosis; Choline; Cystine; Diet; Hyperlipidemias; Methionine; Rats; Thrombosis | 1966 |