choline has been researched along with Thrombosis in 20 studies
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gut microbes influence cardiovascular disease and thrombosis risks through the production of trimethylamine N-oxide (TMAO)." | 5.27 | Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential. ( DiDonato, JA; Fischbach, MA; Guo, CJ; Haag, B; Hazen, SL; Jia, X; Kirsop, J; Lang, JM; Lusis, AJ; Rey, FE; Romano, KA; Skye, SM; Tang, WHW; Wang, Z; Zhu, W, 2018) |
| "Endothelial TF contributes to TMAO-related arterial thrombosis potential, and can be specifically blocked by targeted non-lethal inhibition of gut microbial choline TMA-lyase." | 4.12 | Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis. ( Buffa, JA; DiDonato, JA; Friebel, J; Haghikia, A; Hazen, SL; Kirchhofer, D; Landmesser, U; Li, L; Li, XS; Lüscher, TF; Mach, F; Matter, CM; Räber, L; Rauch, U; Sangwan, N; Tang, WHW; Tizian, C; Wang, Z; Witkowski, M, 2022) |
| " Furthermore, unlike chronic dietary choline, TML supplementation in mice failed to elevate plasma TMAO or heighten thrombosis potential in vivo." | 3.88 | Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. ( Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y, 2018) |
| "Phenylacetylglutamine, for example, was recently shown to promote adverse cardiovascular phenotypes in the host via interaction with multiple ARs (adrenergic receptors)-a class of key receptors that regulate cardiovascular homeostasis." | 2.66 | Gut Microbiota and Cardiovascular Disease. ( Hazen, SL; Weeks, TL; Witkowski, M, 2020) |
| "18 F-choline PET/CT was performed for initial staging and displayed several intense foci uptake of sternum and thoracic vertebrae, suggestive of bone metastasis." | 1.91 | A False-Positive Bone Oligometastatic Prostate Cancer in 18 F-Choline PET/CT : Be Aware of Chronic Vascular Pitfalls. ( Kryza, D; Larrouquere, L; Mognetti, T; Moreau, A; Pretet, V, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 4 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tu, R | 1 |
| Xia, J | 1 |
| Pretet, V | 1 |
| Moreau, A | 1 |
| Larrouquere, L | 1 |
| Mognetti, T | 1 |
| Kryza, D | 1 |
| Witkowski, M | 3 |
| Weeks, TL | 1 |
| Hazen, SL | 8 |
| Friebel, J | 1 |
| Buffa, JA | 4 |
| Li, XS | 2 |
| Wang, Z | 7 |
| Sangwan, N | 1 |
| Li, L | 4 |
| DiDonato, JA | 5 |
| Tizian, C | 1 |
| Haghikia, A | 1 |
| Kirchhofer, D | 1 |
| Mach, F | 1 |
| Räber, L | 1 |
| Matter, CM | 1 |
| Tang, WHW | 5 |
| Landmesser, U | 1 |
| Lüscher, TF | 2 |
| Rauch, U | 1 |
| Zhu, W | 5 |
| Marosfoi, M | 1 |
| Clarencon, F | 1 |
| Langan, ET | 1 |
| King, RM | 1 |
| Brooks, OW | 1 |
| Tamura, T | 1 |
| Wainwright, JM | 1 |
| Gounis, MJ | 1 |
| Vedantham, S | 1 |
| Puri, AS | 1 |
| Cajka, T | 1 |
| Nemet, I | 1 |
| Hurd, AG | 2 |
| Gu, X | 2 |
| Skye, SM | 3 |
| Roberts, AB | 2 |
| Wu, Y | 2 |
| Shahen, CJ | 1 |
| Wagner, MA | 1 |
| Hartiala, JA | 1 |
| Kerby, RL | 1 |
| Romano, KA | 2 |
| Han, Y | 1 |
| Obeid, S | 1 |
| Allayee, H | 2 |
| Rey, FE | 2 |
| Fiehn, O | 1 |
| Gupta, N | 2 |
| Cody, DB | 1 |
| Levison, BS | 1 |
| Barrington, WT | 1 |
| Russell, MW | 1 |
| Reed, JM | 1 |
| Duzan, A | 1 |
| Lang, JM | 2 |
| Fu, X | 2 |
| Myers, AJ | 1 |
| Rachakonda, S | 1 |
| Brown, JM | 3 |
| Gogonea, V | 1 |
| Lusis, AJ | 4 |
| Garcia-Garcia, JC | 1 |
| Guo, CJ | 1 |
| Jia, X | 2 |
| Kirsop, J | 1 |
| Haag, B | 1 |
| Fischbach, MA | 1 |
| Shih, DM | 1 |
| Schugar, RC | 1 |
| Meng, Y | 1 |
| Miikeda, A | 1 |
| Zieger, M | 1 |
| Lee, R | 1 |
| Graham, M | 1 |
| Cantor, RM | 1 |
| Mueller, C | 1 |
| Gregory, JC | 1 |
| Org, E | 1 |
| Mehrabian, M | 1 |
| Sartor, RB | 1 |
| McIntyre, TM | 1 |
| Silverstein, RL | 1 |
| Tilg, H | 1 |
| RENAUD, S | 2 |
| ALLARD, C | 1 |
| MORELLI, AC | 1 |
| Durrani, AA | 1 |
| Hayward, JA | 1 |
| Chapman, D | 1 |
| Perry, TL | 1 |
| Hansen, S | 1 |
| Love, DL | 1 |
| Crawford, LE | 1 |
| Tischler, B | 1 |
| Vittori, C | 1 |
| Borri, P | 1 |
| Bianchi, V | 1 |
| Kuznik, BI | 1 |
| Mishchenko, VP | 1 |
| Thomas, HM | 1 |
| Williams, WL | 1 |
| Clower, BR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
| "Plant-Based Meat vs Animal Red Meat: a Randomized Cross-over Trial"[NCT04510324] | 41 participants (Actual) | Interventional | 2020-11-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for choline and Thrombosis
| Article | Year |
|---|---|
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO.
Topics: Choline; Cognitive Dysfunction; Gastrointestinal Microbiome; Humans; Inflammation; Stroke; Thrombosi | 2024 |
Gut Microbiota and Cardiovascular Disease.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Cardiovascular Diseases; Carnitine; Choline; Disease | 2020 |
[Role of the heart and vessels in regulating blood coagulation and fibrinolysis].
Topics: Animals; Antifibrinolytic Agents; Blood Coagulation; Blood Platelets; Blood Pressure; Blood Vessels; | 1973 |
2 trials available for choline and Thrombosis
| Article | Year |
|---|---|
Gut Microbe-Generated Trimethylamine
Topics: Adult; Aspirin; Choline; Dietary Fats; Female; Gastrointestinal Microbiome; Humans; Male; Methylamin | 2017 |
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
Topics: Adult; Animals; Bacterial Proteins; Choline; Clostridium; Fecal Microbiota Transplantation; Female; | 2018 |
15 other studies available for choline and Thrombosis
| Article | Year |
|---|---|
A False-Positive Bone Oligometastatic Prostate Cancer in 18 F-Choline PET/CT : Be Aware of Chronic Vascular Pitfalls.
Topics: Aged; Choline; Humans; Male; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; | 2023 |
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis.
Topics: Animals; Choline; Endothelial Cells; Humans; Lyases; Methylamines; Mice; Thromboplastin; Thrombosis | 2022 |
Acute thrombus formation on phosphorilcholine surface modified flow diverters.
Topics: Angioplasty; Animals; Choline; Female; Intracranial Aneurysm; Pancreatic Elastase; Phosphorus; Rabbi | 2018 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Mo | 2018 |
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Topics: Animals; Bacteria; Choline; Diet; Gastrointestinal Microbiome; Hexanols; Mice, Inbred C57BL; Oxidore | 2018 |
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mic | 2019 |
Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Topics: Animals; Blood Platelets; Calcium; Carotid Artery Injuries; Cecum; Chlorides; Choline; Diet; Female; | 2016 |
A Gut Feeling about Thrombosis.
Topics: Animals; Choline; Gastrointestinal Microbiome; Humans; Methylamines; Mice; Plasmalogens; Risk Factor | 2016 |
DIETARY FATS, VITAMINS AND BILE ACIDS IN THE PRODUCTION OF THROMBOSIS AND HYPERLIPEMIA IN RATS.
Topics: Bile Acids and Salts; Blood Chemical Analysis; Butter; Cholesterol; Choline; Coronary Disease; Dieta | 1963 |
[ELEVATION OF THE DEPRESSED THROMBOLYTIC ACTIVITY, IN ARTERIOSCLEROTICS SUBJECTED TO PROLONGED ORAL ANTICOAGULANT THERAPY, USING A DERIVATIVE OF NICOTINIC ACID].
Topics: Aminocaproates; Aminocaproic Acid; Anticoagulants; Arteriosclerosis; Blood Coagulation Tests; Cholin | 1963 |
Biomembranes as models for polymer surfaces. II. The syntheses of reactive species for covalent coupling of phosphorylcholine to polymer surfaces.
Topics: Biocompatible Materials; Blood Cells; Cell Membrane; Choline; Humans; Membranes, Artificial; Phospho | 1986 |
Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Choline; Cys | 1968 |
[On the comparative results of the use of Clarisco in peripheral vascular diseases].
Topics: Aged; Arteriosclerosis Obliterans; Choline; Coronary Disease; Folic Acid; Gangrene; Heparin; Humans; | 1970 |
Cardiac lesions in C mice. Result of choline-deficient and choline-supplemented diets.
Topics: Animals; Calcinosis; Choline; Choline Deficiency; Coronary Vessels; Fibroblasts; Heart Atria; Heart | 1968 |
Prevention by methionine feeding of atherosclerosis and thrombosis in hyperlipemic rats.
Topics: Animals; Arteriosclerosis; Choline; Cystine; Diet; Hyperlipidemias; Methionine; Rats; Thrombosis | 1966 |