Page last updated: 2024-10-16

choline and Syndrome

choline has been researched along with Syndrome in 29 studies

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"We have found that mutant acetylcholine receptor channels (AChRs) that cause slow-channel congenital myasthenic syndromes are activated by serum and that the high frequency of openings in serum is reduced by treatment with choline oxidase."7.70Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes. ( Auerbach, A; Engel, AG; Zhou, M, 1999)
"A peripheral and cerebral cholinergic syndrome was induced in mice by oxotremorine administration; pretreatment orally with cytidine diphosphocholine (CDP-choline) does not potentiate this syndrome and even antagonizes oxotremorine-induced salivation."7.67Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine. ( Boismare, F; Chadelaud, M; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1985)
" Addition of supplemental choline to a biotin-deficient diet decreased the biotin status of chicks and increased mortality from fatty liver and kidney syndrome (FLKS)."7.66Interrelationships between biotin, choline and other B-vitamins and the occurrence of fatty liver and kidney syndrome and sudden death syndrome in broiler chickens. ( Randall, CJ; Whitehead, CC, 1982)
"Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function."6.71Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003)
" The dose-response relationship between feed intake, liver hemorrhagic score and liver lipid content was again demonstrated."5.25Effect of inositol, lecithin, vitamins (B12 with choline and E), and iodinated casein on induced fatty liver-hemorrhagic syndrome in laying chickens. ( Polin, D; Wolford, JH, 1975)
" Cerebral MRI shows hypomyelinated white matter and cerebellar atrophy; 1H-MRS of white matter reveals a marked elevation of myo-inositol."3.73Leukoencephalopathy with ataxia, hypodontia, and hypomyelination. ( Boltshauser, E; Ebinger, F; Harting, I; Hoffmann, GF; Koch, MJ; Martin, E; Rating, D; Schmitt-Mechelke, T; Uhlenberg, B; Weber, L; Wiegand, G; Wolf, NI; Zschocke, J, 2005)
"We have found that mutant acetylcholine receptor channels (AChRs) that cause slow-channel congenital myasthenic syndromes are activated by serum and that the high frequency of openings in serum is reduced by treatment with choline oxidase."3.70Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes. ( Auerbach, A; Engel, AG; Zhou, M, 1999)
"A peripheral and cerebral cholinergic syndrome was induced in mice by oxotremorine administration; pretreatment orally with cytidine diphosphocholine (CDP-choline) does not potentiate this syndrome and even antagonizes oxotremorine-induced salivation."3.67Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine. ( Boismare, F; Chadelaud, M; Chretien, P; Daoust, M; Moore, N; Saligaut, C, 1985)
" Addition of supplemental choline to a biotin-deficient diet decreased the biotin status of chicks and increased mortality from fatty liver and kidney syndrome (FLKS)."3.66Interrelationships between biotin, choline and other B-vitamins and the occurrence of fatty liver and kidney syndrome and sudden death syndrome in broiler chickens. ( Randall, CJ; Whitehead, CC, 1982)
"Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function."2.71Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003)
"Choline treatments could restore the membrane lipids, repair cellular organelles and protect mutant cells from acute iron overload."1.56Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. ( Agarwal, P; Bakovic, M; Brady, L; Distelmaier, F; Dolinsky, VW; Fagerberg, CR; Gade, E; Hejbøl, EK; Jamra, RA; Kibæk, M; Klee, D; Larsen, MJ; Markovic, L; Nagy, P; Rouse, N; Schrøder, HD; Seibt, A; Tarnopolsky, M; Taylor, A; Wieczorek, D, 2020)
"PEHO syndrome is a rare symptom complex of severe progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy."1.33Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome. ( Boltshauser, E; Huisman, TA; Klein, A; Straube, T; Werner, B, 2006)
"Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging."1.31Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002)
"The metabolic disturbances indicate disease progression but are less pronounced than in older patients with hemimegalencephaly."1.30Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome. ( Christen, HJ; Frahm, J; Hanefeld, FA; Kruse, B; Pouwels, PJ, 1998)
"Deanol did not produce the anticipated elevation in choline levels postulated to be one mechanism of its action."1.26Deanol acetamidobenzoate (Deaner) in tardive dyskinesia. ( Fann, WE; Stafford, JR, 1977)
" The dose-response relationship between feed intake, liver hemorrhagic score and liver lipid content was again demonstrated."1.25Effect of inositol, lecithin, vitamins (B12 with choline and E), and iodinated casein on induced fatty liver-hemorrhagic syndrome in laying chickens. ( Polin, D; Wolford, JH, 1975)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199013 (44.83)18.7374
1990's3 (10.34)18.2507
2000's9 (31.03)29.6817
2010's3 (10.34)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Fagerberg, CR1
Taylor, A1
Distelmaier, F1
Schrøder, HD1
Kibæk, M1
Wieczorek, D1
Tarnopolsky, M1
Brady, L1
Larsen, MJ1
Jamra, RA1
Seibt, A1
Hejbøl, EK1
Gade, E1
Markovic, L1
Klee, D1
Nagy, P1
Rouse, N1
Agarwal, P1
Dolinsky, VW1
Bakovic, M1
Harper, DE1
Ichesco, E1
Schrepf, A1
Halvorson, M1
Puiu, T1
Clauw, DJ1
Harris, RE1
Harte, SE1
Stromillo, ML1
Giorgio, A1
Rossi, F1
Battaglini, M1
Hakiki, B1
Malentacchi, G1
Santangelo, M1
Gasperini, C1
Bartolozzi, ML1
Portaccio, E1
Amato, MP1
De Stefano, N1
Abe, Y1
Yamamoto, T1
Soeda, T1
Kumagai, T1
Tanno, Y1
Kubo, J1
Ishihara, T1
Katayama, S1
Seth, A1
Truscott, S1
Chew, J1
Kaufman, MJ1
Henry, ME1
Frederick, Bd1
Hennen, J1
Villafuerte, RA1
Stoddard, EP1
Schmidt, ME1
Cohen, BM1
Renshaw, PF1
DIAMANT, H1
Marszał, E1
Jamroz, E1
Paprocka, J1
Kluczewska, E1
Sokół, M1
Nagae-Poetscher, LM1
Bibat, G1
Philippart, M1
Rosemberg, S1
Fatemi, A1
Lacerda, MT1
Costa, MO1
Kok, F1
Costa Leite, C1
Horská, A1
Barker, PB2
Naidu, S1
Wolf, NI1
Harting, I1
Boltshauser, E2
Wiegand, G1
Koch, MJ1
Schmitt-Mechelke, T1
Martin, E1
Zschocke, J1
Uhlenberg, B1
Hoffmann, GF1
Weber, L1
Ebinger, F1
Rating, D1
Sijens, PE1
Verbruggen, KT1
Meiners, LC1
Soorani-Lunsing, RJ1
Rake, JP1
Oudkerk, M1
Huisman, TA1
Klein, A1
Werner, B1
Straube, T1
Collinson, PO1
Gaze, DC1
Paggi, A1
Quattrini, A1
Ortenzi, A1
Cianci, F1
Silvestri, R1
Mancini, S1
Whitehead, CC2
Randall, CJ1
Chen, H1
Aiello, F1
Kruse, B1
Pouwels, PJ1
Christen, HJ1
Frahm, J1
Hanefeld, FA1
Zhou, M1
Engel, AG1
Auerbach, A1
Eichler, FS1
Wang, P1
Wityk, RJ1
Beauchamp, NJ1
Wolford, JH2
Polin, D1
Stafford, JR1
Fann, WE1
Pearce, J1
Tucek, S1
Svoboda, T1
Rícný, J1
Bass, A1
Soukup, T1
Vítek, V1
Saligaut, C1
Daoust, M1
Chadelaud, M1
Moore, N1
Chretien, P1
Boismare, F1
Finocchiaro, G1
Di Donato, S1
Madonna, M1
Fusi, R1
Ladinsky, H1
Consolo, S1
Rothschild, JG1
Hansen, RC1
Hamilton, PB1
Garlich, JD1
Murphy, D1
Blair, R1
Bannister, DW1
Evans, AJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for choline and Syndrome

ArticleYear
Biomarkers of cardiovascular damage.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2007, Volume: 16, Issue:4

    Topics: Biomarkers; Cardiovascular Diseases; Choline; Electrocardiography; Fatty Acids, Nonesterified; Human

2007
Trimethylaminuria in a girl with Prader-Willi syndrome and del(15)(q11q13).
    American journal of medical genetics, 1993, Feb-01, Volume: 45, Issue:3

    Topics: Animals; Child; Choline; Chromosome Deletion; Chromosomes, Human, Pair 15; Diet; Female; Fishes; Hum

1993

Trials

1 trial available for choline and Syndrome

ArticleYear
Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study.
    Biological psychiatry, 2003, Sep-01, Volume: 54, Issue:5

    Topics: Adult; Brain Mapping; Choline; Depressive Disorder, Major; Female; Fluoxetine; Gyrus Cinguli; Humans

2003

Other Studies

26 other studies available for choline and Syndrome

ArticleYear
Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration.
    Brain : a journal of neurology, 2020, 01-01, Volume: 143, Issue:1

    Topics: Adolescent; Antigens, CD; Ataxia; Atrophy; Cerebellum; Choline; Cognitive Dysfunction; Cytoplasmic V

2020
Relationships between brain metabolite levels, functional connectivity, and negative mood in urologic chronic pelvic pain syndrome patients compared to controls: A MAPP research network study.
    NeuroImage. Clinical, 2018, Volume: 17

    Topics: Adult; Brain; Choline; Chronic Pain; Cross-Sectional Studies; Emotions; Female; gamma-Aminobutyric A

2018
Brain metabolic changes suggestive of axonal damage in radiologically isolated syndrome.
    Neurology, 2013, Jun-04, Volume: 80, Issue:23

    Topics: Adult; Aspartic Acid; Axons; Brain; Choline; Creatine; Disease Progression; Female; Humans; Magnetic

2013
Diabetic striatal disease: clinical presentation, neuroimaging, and pathology.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:13

    Topics: Adolescent; Aged; Aged, 80 and over; Aspartic Acid; Choline; Chorea; Corpus Striatum; Creatine; Diab

2009
Health supplement associated with intraoperative floppy-iris syndrome.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:6

    Topics: Antioxidants; Cataract Extraction; Choline; Dietary Supplements; Female; Humans; Intraoperative Comp

2010
Cholinesterase inhibitors and vestibular function; a study of a vestibular syndrome in guinea-pigs caused by intracarotid centripetal injection of cholinesterase inhibitors and cholinesters.
    Acta oto-laryngologica. Supplementum, 1954, Volume: 111

    Topics: Choline; Cholinesterase Inhibitors; Disease; Ear, Inner; Guinea Pigs; Syndrome; Vestibular Diseases;

1954
Leukoencephalopathy with macrocephaly and mild clinical course.
    Neurologia i neurochirurgia polska, 2004, Volume: 38, Issue:1 Suppl 1

    Topics: Abnormalities, Multiple; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Creatinine; Dementi

2004
Leukoencephalopathy, cerebral calcifications, and cysts: new observations.
    Neurology, 2004, Apr-13, Volume: 62, Issue:7

    Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Calcinosis; Central Nervous System Cysts; Child; C

2004
Leukoencephalopathy with ataxia, hypodontia, and hypomyelination.
    Neurology, 2005, Apr-26, Volume: 64, Issue:8

    Topics: Age of Onset; Anodontia; Ataxia; Atrophy; Basal Ganglia; Body Height; Brain; Cerebellum; Child; Chil

2005
1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter.
    European radiology, 2005, Volume: 15, Issue:9

    Topics: Aspartic Acid; Brain Chemistry; Child, Preschool; Choline; Creatine; Glutamic Acid; Glycine; Guanidi

2005
Serial MR imaging, diffusion tensor imaging, and MR spectroscopic findings in a child with progressive encephalopathy, edema, hypsarrhythmia, and optic atrophy (PEHO) syndrome.
    AJNR. American journal of neuroradiology, 2006, Volume: 27, Issue:7

    Topics: Aspartic Acid; Atrophy; Brain Diseases; Brain Edema; Cerebellum; Child; Choline; Creatine; Diffusion

2006
[Dementia syndromes and epilepsy].
    Minerva medica, 1984, Feb-18, Volume: 75, Issue:6

    Topics: Adult; Aged; Alzheimer Disease; Choline; Dementia; Electroencephalography; Epilepsy; Female; Humans;

1984
Interrelationships between biotin, choline and other B-vitamins and the occurrence of fatty liver and kidney syndrome and sudden death syndrome in broiler chickens.
    The British journal of nutrition, 1982, Volume: 48, Issue:1

    Topics: Animals; Biotin; Chickens; Choline; Death, Sudden; Diet; Fatty Liver; Female; Kidney Diseases; Male;

1982
Proton magnetic resonance spectroscopy of linear nevus sebaceus syndrome.
    Pediatric neurology, 1998, Volume: 18, Issue:2

    Topics: Aspartic Acid; Brain Chemistry; Cerebral Cortex; Child, Preschool; Choline; Creatine; Disease Progre

1998
Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Aug-31, Volume: 96, Issue:18

    Topics: Animals; Cell Line; Choline; Humans; Kidney; Membrane Potentials; Mice; Mutation; Myasthenia Gravis;

1999
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet

2002
Effect of inositol, lecithin, vitamins (B12 with choline and E), and iodinated casein on induced fatty liver-hemorrhagic syndrome in laying chickens.
    Poultry science, 1975, Volume: 54, Issue:4

    Topics: Animal Feed; Animals; Caseins; Chickens; Choline; Eggs; Fatty Liver; Female; Hemorrhage; Inositol; I

1975
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Choline; Cyproheptadine; Deanol; Drug Evaluation; Dyskinesia, Drug-Induced; Ethanolamines; Humans; M

1977
The effects of choline and inositol on hepatic lipid metabolism and the incidence of the fatty liver and kidney syndrome in broilers.
    British poultry science, 1975, Volume: 16, Issue:6

    Topics: Animal Feed; Animals; ATP Citrate (pro-S)-Lyase; Chickens; Choline; Dietary Proteins; Fatty Liver; I

1975
The concentration of choline and the activities of cholinesterases, creatine kinase and lactate dehydrogenase in the blood plasma of piglets with the syndrome of splayleg (congenital myofibrillar hypoplasia).
    Zentralblatt fur Veterinarmedizin. Reihe A, 1985, Volume: 32, Issue:1

    Topics: Animals; Choline; Cholinesterases; Creatine Kinase; L-Lactate Dehydrogenase; Muscular Diseases; Swin

1985
Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:1

    Topics: Administration, Oral; Animals; Choline; Cytidine Diphosphate Choline; Diarrhea; Female; Hypothermia;

1985
An approach using lecithin treatment for olivopontocerebellar atrophies.
    European neurology, 1985, Volume: 24, Issue:6

    Topics: Adult; Cerebellar Ataxia; Cholesterol, HDL; Choline; Cranial Nerves; Electromyography; Female; Human

1985
Fish odor syndrome: trimethylaminuria with milk as chief dietary factor.
    Pediatric dermatology, 1985, Volume: 3, Issue:1

    Topics: Animals; Cattle; Child; Choline; Humans; Infant; Liver; Male; Methylamines; Milk; Syndrome

1985
Failure of vitamin supplementation to alter the fatty liver syndrome caused by aflatoxin.
    Poultry science, 1972, Volume: 51, Issue:2

    Topics: Aflatoxins; Animals; Aspergillus flavus; Chickens; Choline; Fatty Liver; Female; Inositol; Lipids; L

1972
Effect of diet on fatty liver-hemorrhagic syndrome incidence in laying chickens.
    Poultry science, 1972, Volume: 51, Issue:6

    Topics: Animals; Body Weight; Chickens; Choline; Cobalt; Diet; Fatty Liver; Female; Hemorrhage; Inositol; Li

1972
Involvement of diet in fatty liver and kidney syndrome in broiler chickens.
    The Veterinary record, 1973, Feb-03, Volume: 92, Issue:5

    Topics: Animal Feed; Animals; Chickens; Choline; Diet; Edible Grain; Fatty Liver; Kidney; Kidney Diseases; L

1973