choline has been researched along with Spinocerebellar Ataxias in 5 studies
Spinocerebellar Ataxias: A group of predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Autosomal-dominant spinocerebellar ataxia type 1 (SCA1) is an adult-onset progressive disorder with well-characterized neurodegeneration in the cerebellum and brainstem." | 1.40 | Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1. ( Brandt, AU; Doss, S; Endres, M; Oberwahrenbrock, T; Paul, F; Rinnenthal, JL, 2014) |
| "Spinocerebellar ataxia type 1 (SCA1) is a hereditary, progressive and fatal movement disorder that primarily affects the cerebellum." | 1.39 | Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1. ( Brent Clark, H; Eberly, LE; Emir, UE; Öz, G; Vollmers, ML, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Emir, UE | 1 |
| Brent Clark, H | 1 |
| Vollmers, ML | 1 |
| Eberly, LE | 1 |
| Öz, G | 1 |
| Doss, S | 1 |
| Brandt, AU | 1 |
| Oberwahrenbrock, T | 1 |
| Endres, M | 1 |
| Paul, F | 1 |
| Rinnenthal, JL | 1 |
| Harno, H | 1 |
| Heikkinen, S | 1 |
| Kaunisto, MA | 1 |
| Kallela, M | 1 |
| Häkkinen, AM | 1 |
| Wessman, M | 1 |
| Färkkilä, M | 1 |
| Lundbom, N | 1 |
| Boesch, SM | 2 |
| Wolf, C | 1 |
| Seppi, K | 1 |
| Felber, S | 2 |
| Wenning, GK | 1 |
| Schocke, M | 2 |
| Bürk, K | 1 |
| Hollosi, P | 1 |
| Fornai, F | 1 |
| Aichner, FT | 1 |
| Poewe, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 2 Study of 4-Aminopyridine for the Treatment of Episodic Ataxia Type 2[NCT01543750] | Phase 2 | 0 participants (Actual) | Interventional | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for choline and Spinocerebellar Ataxias
| Article | Year |
|---|---|
Differentiation of SCA2 from MSA-C using proton magnetic resonance spectroscopic imaging.
Topics: Adult; Age of Onset; Aged; Aspartic Acid; Cerebellum; Choline; Creatine; Diagnosis, Differential; Fe | 2007 |
4 other studies available for choline and Spinocerebellar Ataxias
| Article | Year |
|---|---|
Non-invasive detection of neurochemical changes prior to overt pathology in a mouse model of spinocerebellar ataxia type 1.
Topics: Animals; Ataxin-1; Ataxins; Cerebellum; Choline; Disease Models, Animal; Disease Progression; Gene K | 2013 |
Metabolic evidence for cerebral neurodegeneration in spinocerebellar ataxia type 1.
Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Brain; Cerebral Cortex; Choline; Creatine; Female; | 2014 |
Decreased cerebellar total creatine in episodic ataxia type 2: a 1H MRS study.
Topics: Adolescent; Adult; Aspartic Acid; Calcium Channels; Cerebellum; Child; Choline; Creatine; Dysarthria | 2005 |
Proton magnetic resonance spectroscopic imaging reveals differences in spinocerebellar ataxia types 2 and 6.
Topics: Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy; Male; Midd | 2001 |