Page last updated: 2024-10-16

choline and Sleep Apnea, Obstructive

choline has been researched along with Sleep Apnea, Obstructive in 10 studies

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

ExcerptRelevanceReference
"This pilot study is the first to show that lower levels of plasma choline metabolites are associated with sleepiness."7.88Lower plasma choline levels are associated with sleepiness symptoms. ( Dai, F; Gooneratne, NS; Keenan, BT; Pack, AI; Pak, VM, 2018)
"This pilot study is the first to show that lower levels of plasma choline metabolites are associated with sleepiness."3.88Lower plasma choline levels are associated with sleepiness symptoms. ( Dai, F; Gooneratne, NS; Keenan, BT; Pack, AI; Pak, VM, 2018)
"Univariate ANOVA disclosed significant effects of AHI, age, and the presence or absence of hypertension on the NAA/choline ratio for cerebral white matter (p=0."3.71Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change. ( Chen, W; Higami, S; Inoue, Y; Kamba, M; Ogawa, T; Suto, Y, 2001)
"The study includes 33 subjects with obstructive sleep apnea and 10 healthy controls (HC)."1.56Cholinergic Markers and Cytokines in OSA Patients. ( Cerroni, G; Costantini, E; D'Angelo, C; Di Nicola, M; Guarnieri, B; Marchioni, M; Reale, M; Velluto, L, 2020)
"Adults with obstructive sleep apnea (OSA) show significant autonomic and neuropsychologic deficits, which may derive from damage to insular regions that serve those functions."1.40Insular cortex metabolite changes in obstructive sleep apnea. ( Harper, RM; Kumar, R; Macey, PM; Woo, MA; Yadav, SK; Yan-Go, FL, 2014)
"Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function."1.33Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. ( Barker, PB; Degaonkar, M; Earley, CJ; Halbower, AC; Mahone, EM; Marcus, CL; Prahme, MC; Smith, PL, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Reale, M1
Velluto, L1
Di Nicola, M1
D'Angelo, C1
Costantini, E1
Marchioni, M1
Cerroni, G1
Guarnieri, B1
Pak, VM1
Dai, F1
Keenan, BT1
Gooneratne, NS1
Pack, AI1
Yadav, SK1
Kumar, R1
Macey, PM2
Woo, MA1
Yan-Go, FL1
Harper, RM2
Sarma, MK1
Nagarajan, R1
Aysola, R1
Thomas, MA1
Sarchielli, P1
Presciutti, O1
Alberti, A1
Tarducci, R1
Gobbi, G1
Galletti, F1
Costa, C1
Eusebi, P1
Calabresi, P1
Algin, O1
Gokalp, G1
Ocakoglu, G1
Ursavas, A1
Taskapilioglu, O1
Hakyemez, B1
Alchanatis, M1
Deligiorgis, N1
Zias, N1
Amfilochiou, A1
Gotsis, E1
Karakatsani, A1
Papadimitriou, A1
Halbower, AC1
Degaonkar, M1
Barker, PB1
Earley, CJ1
Marcus, CL1
Smith, PL1
Prahme, MC1
Mahone, EM1
Tonon, C1
Vetrugno, R1
Lodi, R1
Gallassi, R1
Provini, F1
Iotti, S1
Plazzi, G1
Montagna, P1
Lugaresi, E1
Barbiroli, B1
Kamba, M1
Inoue, Y1
Higami, S1
Suto, Y1
Ogawa, T1
Chen, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077]70 participants (Anticipated)Interventional2022-05-14Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for choline and Sleep Apnea, Obstructive

ArticleYear
Cholinergic Markers and Cytokines in OSA Patients.
    International journal of molecular sciences, 2020, May-05, Volume: 21, Issue:9

    Topics: Adult; Biomarkers; Case-Control Studies; Choline; Cytokines; Disease Susceptibility; Female; Gene Ex

2020
Lower plasma choline levels are associated with sleepiness symptoms.
    Sleep medicine, 2018, Volume: 44

    Topics: Adult; Biomarkers; Case-Control Studies; Choline; Disorders of Excessive Somnolence; Female; Humans;

2018
Insular cortex metabolite changes in obstructive sleep apnea.
    Sleep, 2014, May-01, Volume: 37, Issue:5

    Topics: Adult; Aspartic Acid; Cerebral Cortex; Choline; Creatine; Cross-Sectional Studies; Female; Humans; I

2014
Accelerated Echo Planer J-resolved Spectroscopic Imaging of Putamen and Thalamus in Obstructive Sleep Apnea.
    Scientific reports, 2016, 09-06, Volume: 6

    Topics: Adult; Biomarkers; Case-Control Studies; Choline; Echo-Planar Imaging; Female; Humans; Male; Middle

2016
A 1H magnetic resonance spectroscopy study in patients with obstructive sleep apnea.
    European journal of neurology, 2008, Volume: 15, Issue:10

    Topics: Adult; Aged; Aspartic Acid; Brain Chemistry; Cell Death; Choline; Comorbidity; Creatinine; Female; F

2008
Neurochemical-structural changes evaluation of brain in patients with obstructive sleep apnea syndrome.
    European journal of radiology, 2012, Volume: 81, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Brain; Case-Control Studies; Choline; Creatine; Diffusion Magnetic Reson

2012
Frontal brain lobe impairment in obstructive sleep apnoea: a proton MR spectroscopy study.
    The European respiratory journal, 2004, Volume: 24, Issue:6

    Topics: Adult; Analysis of Variance; Aspartic Acid; Choline; Creatine; Humans; Inositol; Magnetic Resonance

2004
Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury.
    PLoS medicine, 2006, Volume: 3, Issue:8

    Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Cerebral Cortex; Child; Choline; Cr

2006
Proton magnetic resonance spectroscopy study of brain metabolism in obstructive sleep apnoea syndrome before and after continuous positive airway pressure treatment.
    Sleep, 2007, Volume: 30, Issue:3

    Topics: Adult; Arousal; Aspartic Acid; Blood Pressure; Cerebral Cortex; Choline; Continuous Positive Airway

2007
Cerebral metabolic impairment in patients with obstructive sleep apnoea: an independent association of obstructive sleep apnoea with white matter change.
    Journal of neurology, neurosurgery, and psychiatry, 2001, Volume: 71, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Aspartic Acid; Body Mass Index; Brain Chemistry; Cerebral Cortex;

2001