choline has been researched along with Sandhoff Disease in 1 studies
Sandhoff Disease: An autosomal recessive neurodegenerative disorder characterized by an accumulation of G(M2) GANGLIOSIDE in neurons and other tissues. It is caused by mutation in the common beta subunit of HEXOSAMINIDASE A and HEXOSAMINIDASE B. Thus this disease is also known as the O variant since both hexosaminidase A and B are missing. Clinically, it is indistinguishable from TAY-SACHS DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sandhoff disease is a progressive neurodegenerative disorder caused by mutations in the HEXB gene which encodes for the beta-subunit of beta-hexosaminidase A and B, resulting in ganglioside GM(2) accumulation in the brain." | 1.32 | Phospholipid synthesis is decreased in neuronal tissue in a mouse model of Sandhoff disease. ( Bodennec, J; Buccoliero, R; Futerman, AH; Sandhoff, K; Van Echten-Deckert, G, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buccoliero, R | 1 |
| Bodennec, J | 1 |
| Van Echten-Deckert, G | 1 |
| Sandhoff, K | 1 |
| Futerman, AH | 1 |
1 other study available for choline and Sandhoff Disease
| Article | Year |
|---|---|
Phospholipid synthesis is decreased in neuronal tissue in a mouse model of Sandhoff disease.
Topics: Animals; beta-N-Acetylhexosaminidases; Brain; Carbon Radioisotopes; CDPdiacylglycerol-Serine O-Phosp | 2004 |