choline has been researched along with Retinoblastoma in 5 studies
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of physiological concentrations of ethanolamine on choline uptake and incorporation into phosphatidylcholine was investigated in human Y79 retinoblastoma cells, a multipotential, undifferentiated retinal cell line that has retained many neural characteristics." | 7.67 | Effect of ethanolamine on choline uptake and incorporation into phosphatidylcholine in human Y79 retinoblastoma cells. ( Dunlap, JA; Ginsberg, BH; Spector, AA; Yorek, MA, 1986) |
| "Choline uptake in Y79 human retinoblastoma cells occurs through two kinetically distinguishable processes." | 7.66 | Choline uptake in cultured human Y79 retinoblastoma cells: effect of polyunsaturated fatty acid compositional modifications. ( Hyman, BT; Spector, AA, 1982) |
| "Multivariate analysis identified three metabolic subgroups of retinoblastoma, with the most discriminatory metabolites being taurine, hypotaurine, total-choline and creatine." | 3.81 | Metabolite profiling in retinoblastoma identifies novel clinicopathological subgroups. ( Brundler, MA; Jenkinson, H; Kohe, S; McConville, CM; Parulekar, M; Peet, AC; Wilson, M, 2015) |
| "The effect of physiological concentrations of ethanolamine on choline uptake and incorporation into phosphatidylcholine was investigated in human Y79 retinoblastoma cells, a multipotential, undifferentiated retinal cell line that has retained many neural characteristics." | 3.67 | Effect of ethanolamine on choline uptake and incorporation into phosphatidylcholine in human Y79 retinoblastoma cells. ( Dunlap, JA; Ginsberg, BH; Spector, AA; Yorek, MA, 1986) |
| "Choline uptake in Y79 human retinoblastoma cells occurs through two kinetically distinguishable processes." | 3.66 | Choline uptake in cultured human Y79 retinoblastoma cells: effect of polyunsaturated fatty acid compositional modifications. ( Hyman, BT; Spector, AA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohe, S | 1 |
| Brundler, MA | 1 |
| Jenkinson, H | 1 |
| Parulekar, M | 1 |
| Wilson, M | 1 |
| Peet, AC | 1 |
| McConville, CM | 1 |
| Hyman, BT | 1 |
| Spector, AA | 3 |
| Treen, M | 1 |
| Uauy, RD | 1 |
| Jameson, DM | 1 |
| Thomas, VL | 1 |
| Hoffman, DR | 1 |
| Yorek, MA | 2 |
| Dunlap, JA | 1 |
| Ginsberg, BH | 1 |
| Rosario, RT | 1 |
| Dudley, DT | 1 |
5 other studies available for choline and Retinoblastoma
| Article | Year |
|---|---|
Metabolite profiling in retinoblastoma identifies novel clinicopathological subgroups.
Topics: Adolescent; Adult; Aged, 80 and over; Cell Differentiation; Child; Choline; Creatine; Female; Humans | 2015 |
Choline uptake in cultured human Y79 retinoblastoma cells: effect of polyunsaturated fatty acid compositional modifications.
Topics: Biological Transport; Cell Line; Choline; Eye Neoplasms; Fatty Acids, Unsaturated; Humans; Kinetics; | 1982 |
Effect of docosahexaenoic acid on membrane fluidity and function in intact cultured Y-79 retinoblastoma cells.
Topics: Cell Line; Cell Membrane; Choline; Culture Media; Docosahexaenoic Acids; Eye Neoplasms; Fatty Acids; | 1992 |
Effect of ethanolamine on choline uptake and incorporation into phosphatidylcholine in human Y79 retinoblastoma cells.
Topics: Biological Transport; Cell Line; Choline; Ethanolamine; Ethanolamines; Eye Neoplasms; Humans; Kineti | 1986 |
The utilization of ethanolamine and serine for ethanolamine phosphoglyceride synthesis by human Y79 retinoblastoma cells.
Topics: Cell Line; Choline; Ethanolamine; Ethanolamines; Eye Neoplasms; Hemicholinium 3; Humans; Kinetics; P | 1985 |