choline has been researched along with Renal Insufficiency, Chronic in 17 studies
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 7.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "2% adenine diet for 14 weeks developed CKD with elevated plasma levels of TMAO, provision of a non-lethal inhibitor of gut microbial trimethylamine (TMA) production, iodomethylcholine (IMC), significantly reduced multiple markers of renal injury (plasma creatinine, cystatin C, FGF23, and TMAO), reduced histopathologic evidence of fibrosis, and markedly attenuated development of microalbuminuria." | 4.02 | Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice. ( Charugundla, S; Guo, F; Hazen, SL; Jia, X; Kaczor-Urbanowicz, KE; Lusis, AJ; Magyar, C; Miikeda, A; Nicholas, SB; Pellegrini, M; Shih, DM; Wang, Z; Zhang, W; Zhou, Z; Zuckerman, J, 2021) |
| "Gut microbial metabolism of dietary choline, a nutrient abundant in a Western diet, produces trimethylamine (TMA) and the atherothrombosis- and fibrosis-promoting metabolite TMA-N-oxide (TMAO)." | 3.96 | Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease. ( Buffa, JA; DiDonato, JA; Gupta, N; Hazen, SL; Ho, KJ; Li, L; Roberts, AB; Sangwan, N; Skye, SM; Tang, WHW; Varga, J, 2020) |
| "In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion." | 3.88 | Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018) |
| "Hyperhomocysteinemia has undoubtedly a central role in such a prominent cardiovascular burden." | 2.66 | Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery. ( Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T, 2020) |
| "Choline is a water-soluble nutrient essential for human life." | 2.66 | The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases. ( Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A, 2020) |
| "Choline is an amine osmolyte with antioxidant potential." | 1.72 | Short Report: Choline plasma levels are related to Nrf2 transcriptional expression in chronic kidney disease? ( Bergman, P; Cardozo, L; Mafra, D; Ribeiro-Alves, M; Shiels, PG; Stenvinkel, P, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 9 (52.94) | 2.80 |
| Authors | Studies |
|---|---|
| Berdichevsky, BA | 1 |
| Berdichevsky, VB | 1 |
| Sapozhenkova, EV | 1 |
| Romanova, AV | 1 |
| Rasulov, FR | 1 |
| Korabelnikov, MA | 1 |
| Mafra, D | 2 |
| Cardozo, L | 1 |
| Ribeiro-Alves, M | 1 |
| Bergman, P | 3 |
| Shiels, PG | 2 |
| Stenvinkel, P | 3 |
| Pelletier, CC | 1 |
| Croyal, M | 1 |
| Ene, L | 1 |
| Aguesse, A | 1 |
| Billon-Crossouard, S | 1 |
| Krempf, M | 1 |
| Lemoine, S | 1 |
| Guebre-Egziabher, F | 1 |
| Juillard, L | 1 |
| Soulage, CO | 1 |
| Gupta, N | 1 |
| Buffa, JA | 1 |
| Roberts, AB | 1 |
| Sangwan, N | 1 |
| Skye, SM | 1 |
| Li, L | 1 |
| Ho, KJ | 1 |
| Varga, J | 1 |
| DiDonato, JA | 1 |
| Tang, WHW | 1 |
| Hazen, SL | 2 |
| Cappuccilli, M | 1 |
| Bergamini, C | 1 |
| Giacomelli, FA | 1 |
| Cianciolo, G | 1 |
| Donati, G | 1 |
| Conte, D | 1 |
| Natali, T | 1 |
| La Manna, G | 1 |
| Capelli, I | 1 |
| Arias, N | 1 |
| Arboleya, S | 1 |
| Allison, J | 1 |
| Kaliszewska, A | 1 |
| Higarza, SG | 1 |
| Gueimonde, M | 1 |
| Arias, JL | 1 |
| Guo, F | 2 |
| Dai, Q | 1 |
| Zeng, X | 1 |
| Liu, Y | 1 |
| Tan, Z | 1 |
| Zhang, H | 1 |
| Ouyang, D | 1 |
| Ebert, T | 1 |
| Painer, J | 1 |
| Qureshi, AR | 2 |
| Giroud, S | 1 |
| Stalder, G | 1 |
| Kublickiene, K | 1 |
| Göritz, F | 1 |
| Vetter, S | 1 |
| Bieber, C | 1 |
| Fröbert, O | 1 |
| Arnemo, JM | 1 |
| Zedrosser, A | 1 |
| Redtenbacher, I | 1 |
| Johnson, RJ | 1 |
| Zhang, W | 1 |
| Miikeda, A | 1 |
| Zuckerman, J | 1 |
| Jia, X | 1 |
| Charugundla, S | 1 |
| Zhou, Z | 1 |
| Kaczor-Urbanowicz, KE | 1 |
| Magyar, C | 1 |
| Wang, Z | 1 |
| Pellegrini, M | 1 |
| Nicholas, SB | 1 |
| Lusis, AJ | 1 |
| Shih, DM | 1 |
| Aguilar-Ramirez, D | 1 |
| Alegre-Díaz, J | 1 |
| Herrington, WG | 1 |
| Staplin, N | 1 |
| Ramirez-Reyes, R | 1 |
| Gnatiuc, L | 1 |
| Hill, M | 1 |
| Romer, F | 1 |
| Torres, J | 1 |
| Trichia, E | 1 |
| Wade, R | 1 |
| Collins, R | 1 |
| Emberson, JR | 1 |
| Kuri-Morales, P | 1 |
| Tapia-Conyer, R | 1 |
| Shen, TD | 1 |
| Xu, KY | 1 |
| Xia, GH | 1 |
| Lu, JQ | 1 |
| Chen, MX | 1 |
| Zhen, X | 1 |
| Wang, S | 1 |
| You, C | 1 |
| Nie, J | 1 |
| Zhou, HW | 1 |
| Yin, J | 1 |
| Fernandez-Prado, R | 1 |
| Esteras, R | 1 |
| Perez-Gomez, MV | 1 |
| Gracia-Iguacel, C | 1 |
| Gonzalez-Parra, E | 1 |
| Sanz, AB | 1 |
| Ortiz, A | 1 |
| Sanchez-Niño, MD | 1 |
| Elmariah, S | 1 |
| Farrell, LA | 1 |
| Furman, D | 1 |
| Lindman, BR | 1 |
| Shi, X | 1 |
| Morningstar, JE | 1 |
| Rhee, EP | 1 |
| Gerszten, RE | 1 |
| Moraes, C | 1 |
| Fouque, D | 1 |
| Amaral, AC | 1 |
| Missailidis, C | 1 |
| Hällqvist, J | 1 |
| Barany, P | 1 |
| Heimbürger, O | 1 |
| Lindholm, B | 1 |
| ALTIERI, A | 1 |
| SORRENTINO, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD): a Open Label, Multicenter Trial[NCT05838118] | 100 participants (Anticipated) | Interventional | 2023-04-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for choline and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis, | 2020 |
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestina | 2020 |
Diet and Gut Microbiota in Health and Disease.
Topics: Animals; Bacteria; Choline; Diet; Dietary Carbohydrates; Dysbiosis; Fecal Microbiota Transplantation | 2017 |
Nutrients Turned into Toxins: Microbiota Modulation of Nutrient Properties in Chronic Kidney Disease.
Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Microbiome; Humans; Methylamines | 2017 |
Trimethylamine N-Oxide From Gut Microbiota in Chronic Kidney Disease Patients: Focus on Diet.
Topics: Animals; Cardiovascular Diseases; Carnitine; Choline; Diet, Protein-Restricted; Disease Models, Anim | 2015 |
12 other studies available for choline and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
[Retrospective analysis of the results of whole-body PET/CT as a possible tool for clinical examination of the population in order to identify subclinical manifestations of chronic kidney disease (pilot study)].
Topics: Choline; Humans; Pilot Projects; Positron Emission Tomography Computed Tomography; Renal Insufficien | 2022 |
Short Report: Choline plasma levels are related to Nrf2 transcriptional expression in chronic kidney disease?
Topics: Choline; Chromatography, Liquid; Cross-Sectional Studies; Humans; Leukocytes, Mononuclear; Male; NF- | 2022 |
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate | 2019 |
Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease.
Topics: Animals; Bacteria; Bacterial Proteins; Choline; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; | 2020 |
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; M | 2021 |
Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears.
Topics: Adult; Aged; Aged, 80 and over; Animals; Betaine; Biomimetics; Cardiovascular Diseases; Choline; Fem | 2020 |
Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.
Topics: Adenine; Albuminuria; Animals; Cardiomegaly; Choline; Disease Models, Animal; Female; Fibroblast Gro | 2021 |
Association of Kidney Function With NMR-Quantified Lipids, Lipoproteins, and Metabolic Measures in Mexican Adults.
Topics: Adult; Aged; Aged, 80 and over; Apolipoproteins B; Atherosclerosis; Cholesterol; Choline; Diabetes M | 2021 |
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis; | 2017 |
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Fe | 2018 |
Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.
Topics: Adult; Aged; Betaine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Choline; Female; Fibr | 2016 |
[Use of a new preparation in acute and chronic kidney diseases, acute renal insufficiency and toxic states].
Topics: Acute Kidney Injury; Choline; Hormones; Humans; Kidney; Kidney Diseases; Parathyroid Glands; Renal I | 1958 |