choline has been researched along with Pheochromocytoma in 11 studies
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The phorbol ester tumor promotor 12-0-tetradecanoylphorbol-13-acetate (TPA) specifically inhibited the binding of radioiodinated epidermal growth factor (125I-EGF) to rat pheochromocytoma (PC12) cells in a noncompetitive fashion with an apparent Ki of 11-26 nM." | 7.66 | Effects of 12-0-Tetradecanoylphorbol-13-acetate (TPA) on rat pheochromocytoma (PC12) cells: interactions with epidermal growth factor and nerve growth factor. ( End, D; Guroff, G; Tolson, N; Yu, MY, 1982) |
| "In PC12 pheochromocytoma cells whose phospholipids had been prelabelled with [3H]palmitic acid, bradykinin increased the production of [3H]phosphatidic acid." | 3.68 | Bradykinin activates a phospholipase D that hydrolyzes phosphatidylcholine in PC12 cells. ( Horwitz, J, 1991) |
| "PC12, a clonal line of rat pheochromocytoma, accumulates newly synthesized acetylcholine in storage granules." | 3.66 | Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles. ( Howard, BD; Toll, L, 1980) |
| "The phorbol ester tumor promotor 12-0-tetradecanoylphorbol-13-acetate (TPA) specifically inhibited the binding of radioiodinated epidermal growth factor (125I-EGF) to rat pheochromocytoma (PC12) cells in a noncompetitive fashion with an apparent Ki of 11-26 nM." | 3.66 | Effects of 12-0-Tetradecanoylphorbol-13-acetate (TPA) on rat pheochromocytoma (PC12) cells: interactions with epidermal growth factor and nerve growth factor. ( End, D; Guroff, G; Tolson, N; Yu, MY, 1982) |
| "PC12, a clonal line of rat pheochromocytoma, synthesizes, stores, and secretes dopamine and acetylcholine." | 3.66 | Choline and acetylcholine metabolism in PC12 secretory cells. ( Howard, BD; Melega, WP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HAGEN, PB | 1 |
| ZEBROWSKI, E | 1 |
| Toll, L | 2 |
| Howard, BD | 3 |
| End, D | 1 |
| Tolson, N | 1 |
| Yu, MY | 1 |
| Guroff, G | 1 |
| Melega, WP | 1 |
| Rebois, RV | 1 |
| Reynolds, EE | 1 |
| Galdzicki, Z | 1 |
| Fukuyama, R | 1 |
| Wadhwani, KC | 1 |
| Rapoport, SI | 1 |
| Ehrenstein, G | 1 |
| Rubenstein, R | 1 |
| Deng, H | 1 |
| Scalici, CL | 1 |
| Papini, MC | 1 |
| Purkiss, J | 1 |
| Murrin, RA | 1 |
| Owen, PJ | 1 |
| Boarder, MR | 1 |
| Horwitz, J | 1 |
| Sandberg, K | 1 |
| Berry, CJ | 1 |
| Rogers, TB | 1 |
| Matsuoka, I | 1 |
| Satake, R | 1 |
| Kurihara, K | 1 |
11 other studies available for choline and Pheochromocytoma
| Article | Year |
|---|---|
Action of TM 10 (choline 2: 6-xylyl ether bromide) and its beta-methyl derivative on the conversion of dopamine to noradrenaline by chromaffin tissue.
Topics: Adrenal Medulla; Bromides; Catecholamines; Choline; Chromaffin System; Dopamine; Ether; Ethers; Huma | 1962 |
Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles.
Topics: Acetylcholine; Adenosine Triphosphatases; Animals; Biological Transport; Carbonyl Cyanide p-Trifluor | 1980 |
Effects of 12-0-Tetradecanoylphorbol-13-acetate (TPA) on rat pheochromocytoma (PC12) cells: interactions with epidermal growth factor and nerve growth factor.
Topics: Animals; Cell Differentiation; Cell Line; Choline; Drug Interactions; Enzyme Induction; Epidermal Gr | 1982 |
Choline and acetylcholine metabolism in PC12 secretory cells.
Topics: Acetylcholine; Adrenal Gland Neoplasms; Biological Transport, Active; Cell Line; Choline; Cytoplasmi | 1981 |
Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line.
Topics: Acetylcholine; Animals; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line; Chol | 1980 |
beta-Amyloid increases choline conductance of PC12 cells: possible mechanism of toxicity in Alzheimer's disease.
Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid beta-Peptides; Animals; Choline; Electric Conduc | 1994 |
Alterations in neurotransmitter-related enzyme activity in scrapie-infected PC12 cells.
Topics: Acetylcholine; Acetylcholinesterase; Adrenal Gland Neoplasms; Animals; Cell Line; Cell Transformatio | 1991 |
Lack of phospholipase D activity in chromaffin cells: bradykinin-stimulated phosphatidic acid formation involves phospholipase C in chromaffin cells but phospholipase D in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Bradykinin; Cattle; Choline; Chromaffin System; Diacylglycerol Kin | 1991 |
Bradykinin activates a phospholipase D that hydrolyzes phosphatidylcholine in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Bradykinin; Carbachol; Choline; Diglycerides; Enzyme Activation; G | 1991 |
Studies on the intoxication pathway of tetanus toxin in the rat pheochromocytoma (PC12) cell line. Binding, internalization, and inhibition of acetylcholine release.
Topics: Acetylcholine; Adrenal Gland Neoplasms; Animals; Cell Line; Choline; Kinetics; Pheochromocytoma; Rat | 1989 |
Cholinergic differentiation of clonal rat pheochromocytoma cells (PC12) induced by factors contained in glioma-conditioned medium: enhancement of high-affinity choline uptake system and reduction of norepinephrine uptake system.
Topics: Acetylcholine; Adrenal Gland Neoplasms; Animals; Cell Differentiation; Choline; Cholinergic Fibers; | 1986 |