choline has been researched along with Pancreatic Neoplasms in 19 studies
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study quantitatively determined whether in vivo (1)H-MRS on multiple endocrine neoplasia type 1 (Men1) conditional knockout (KO) mice and their wild type (WT) littermates could detect differences in total choline (tCho) levels between tumor and control pancreas." | 3.81 | In vivo proton MR spectroscopy of pancreatic neuroendocrine tumors in a multiple endocrine neoplasia type 1 conditional knockout mouse model. ( Adem, A; Branch, CA; Cahill, SM; Cui, MH; Libutti, SK; Quinn, TJ; Yuan, Z, 2015) |
| "Therefore, the classification of pancreatic cancer patients and precise treatment becomes particularly important." | 1.72 | Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes. ( Fang, Y; Feng, J; Guo, P; Huang, H; Liu, W; Teng, T; Wei, B, 2022) |
| "Additionally, the lipid content in pancreatic cancer was higher than that in chronic pancreatitis." | 1.34 | Discrimination of metabolic profiles of pancreatic cancer from chronic pancreatitis by high-resolution magic angle spinning 1H nuclear magnetic resonance and principal components analysis. ( Chen, Q; Deng, H; Fang, F; He, X; Lu, J; Spraul, M; Yu, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (26.32) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 5 (26.32) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, P | 1 |
| Teng, T | 1 |
| Liu, W | 1 |
| Fang, Y | 1 |
| Wei, B | 1 |
| Feng, J | 1 |
| Huang, H | 1 |
| Fuentes-Baile, M | 1 |
| Bello-Gil, D | 1 |
| Pérez-Valenciano, E | 1 |
| Sanz, JM | 1 |
| García-Morales, P | 1 |
| Maestro, B | 1 |
| Ventero, MP | 1 |
| Alenda, C | 1 |
| Barberá, VM | 1 |
| Saceda, M | 1 |
| Huang, JY | 1 |
| Luu, HN | 1 |
| Butler, LM | 1 |
| Midttun, Ø | 1 |
| Ulvik, A | 1 |
| Wang, R | 1 |
| Jin, A | 1 |
| Gao, YT | 1 |
| Tan, Y | 1 |
| Ueland, PM | 1 |
| Koh, WP | 1 |
| Yuan, JM | 1 |
| Hirai, K | 1 |
| Watanabe, S | 1 |
| Nishijima, N | 1 |
| Shibata, K | 1 |
| Hase, A | 1 |
| Yamanaka, T | 1 |
| Inazu, M | 1 |
| Evangelista, L | 1 |
| Cassarino, G | 1 |
| Capobianco, D | 1 |
| Povolato, M | 1 |
| Battista, S | 1 |
| Rensi, M | 1 |
| Bapiro, TE | 1 |
| Frese, KK | 1 |
| Courtin, A | 1 |
| Bramhall, JL | 1 |
| Madhu, B | 1 |
| Cook, N | 1 |
| Neesse, A | 1 |
| Griffiths, JR | 1 |
| Tuveson, DA | 1 |
| Jodrell, DI | 1 |
| Richards, FM | 1 |
| Penet, MF | 1 |
| Shah, T | 1 |
| Bharti, S | 1 |
| Krishnamachary, B | 1 |
| Artemov, D | 1 |
| Mironchik, Y | 1 |
| Wildes, F | 1 |
| Maitra, A | 1 |
| Bhujwalla, ZM | 1 |
| Cui, MH | 1 |
| Branch, CA | 1 |
| Cahill, SM | 1 |
| Quinn, TJ | 1 |
| Adem, A | 1 |
| Libutti, SK | 1 |
| Yuan, Z | 1 |
| Yao, X | 1 |
| Zeng, M | 1 |
| Wang, H | 1 |
| Fei, S | 1 |
| Rao, S | 1 |
| Ji, Y | 1 |
| Tesiram, YA | 1 |
| Lerner, M | 1 |
| Stewart, C | 1 |
| Njoku, C | 1 |
| Brackett, DJ | 1 |
| MARCHESI, E | 1 |
| PADULA, F | 1 |
| DUKA, TV | 1 |
| NEUMAYR, A | 1 |
| PIETSCHMANN, H | 1 |
| PREIBISCH, W | 1 |
| Henriksen, G | 1 |
| Herz, M | 1 |
| Hauser, A | 1 |
| Schwaiger, M | 1 |
| Wester, HJ | 1 |
| Fang, F | 1 |
| He, X | 1 |
| Deng, H | 1 |
| Chen, Q | 1 |
| Lu, J | 1 |
| Spraul, M | 1 |
| Yu, Y | 1 |
| Ma, Z | 1 |
| Bohrer, A | 1 |
| Wohltmann, M | 1 |
| Ramanadham, S | 1 |
| Hsu, FF | 1 |
| Turk, J | 1 |
| Ventrucci, M | 1 |
| Bolondi, L | 1 |
| Caletti, GC | 1 |
| Fontana, G | 1 |
| Shinozuka, H | 1 |
| Katyal, SL | 1 |
| Lombardi, B | 2 |
| Longnecker, DS | 1 |
| Chandar, N | 1 |
| Sheahan, DG | 1 |
| Janosky, JE | 1 |
1 trial available for choline and Pancreatic Neoplasms
| Article | Year |
|---|---|
[Therapeutic effect of a pharmacologic combination of choleretics and digestive enzymes in exocrine pancreatic insufficiency].
Topics: Adolescent; Adult; Aged; Amylases; Celiac Disease; Cholagogues and Choleretics; Choline; Clinical Tr | 1975 |
18 other studies available for choline and Pancreatic Neoplasms
| Article | Year |
|---|---|
Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes.
Topics: Amino Acids; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Choline; Humans; Pancreatic Neoplasms; | 2022 |
Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes.
Topics: Amino Acids; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Choline; Humans; Pancreatic Neoplasms; | 2022 |
Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes.
Topics: Amino Acids; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Choline; Humans; Pancreatic Neoplasms; | 2022 |
Metabolomic analyses redefine the biological classification of pancreatic cancer and correlate with clinical outcomes.
Topics: Amino Acids; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Choline; Humans; Pancreatic Neoplasms; | 2022 |
CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, induces Cell Death in Human Cancer Cells.
Topics: 3T3-L1 Cells; Adenocarcinoma; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; | 2020 |
A prospective evaluation of serum methionine-related metabolites in relation to pancreatic cancer risk in two prospective cohort studies.
Topics: Betaine; Case-Control Studies; Choline; Female; Humans; Male; Methionine; Methylamines; Middle Aged; | 2020 |
Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Cel | 2020 |
An Incidental Uptake of 18F-Choline at PET/CT in Gastric Neuroendocrine Tumor.
Topics: Aged; Biological Transport; Choline; Humans; Incidental Findings; Intestinal Neoplasms; Male; Neuroe | 2021 |
Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Choline; Deoxycytidine; Diph | 2014 |
Metabolic imaging of pancreatic ductal adenocarcinoma detects altered choline metabolism.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Choline; Humans; Magnetic Resonance Imaging | 2015 |
In vivo proton MR spectroscopy of pancreatic neuroendocrine tumors in a multiple endocrine neoplasia type 1 conditional knockout mouse model.
Topics: Animals; Choline; Female; Magnetic Resonance Imaging; Male; Mice; Mice, Knockout; Multiple Endocrine | 2015 |
Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Choline; Dipeptides; Fatty Acids, Unsaturated; Female | 2012 |
Utility of nuclear magnetic resonance spectroscopy for pancreatic cancer studies.
Topics: Biomarkers, Tumor; Blood Glucose; Case-Control Studies; Choline; Fatty Acids, Unsaturated; Female; H | 2012 |
[THE ASSOCIATION OF SORBITOL, GLUTAMIC ACID AND CHOLINE HYPOSULFITE IN THE THERAPY OF HEPATIC DISEASES AND MINOR HEPATIC INSUFFICIENCY].
Topics: Adolescent; Biliary Dyskinesia; Child; Cholangitis; Cholecystitis; Cholelithiasis; Choline; Dithioni | 1963 |
[EFFECT OF CHOLINE CHLORIDE ON SOME FUNCTIONS OF THE LIVER IN BOTKIN'S DISEASE].
Topics: Chlorides; Choline; Communicable Diseases; Drug Therapy; Hepatitis; Hepatitis A; Humans; Liver Funct | 1964 |
[THE DIAGNOSIS OF CHRONIC PANCREATIC DISEASES BY MEANS OF INTRADUODENAL STUDIES].
Topics: Amylases; Choline; Citrates; Diagnosis, Differential; Duodenum; Gastric Acidity Determination; Gastr | 1965 |
Synthesis and preclinical evaluation of the choline transport tracer deshydroxy-[18F]fluorocholine ([18F]dOC).
Topics: Animals; Biological Transport; Biomarkers, Tumor; Cell Line, Tumor; Choline; Dose-Response Relations | 2004 |
Discrimination of metabolic profiles of pancreatic cancer from chronic pancreatitis by high-resolution magic angle spinning 1H nuclear magnetic resonance and principal components analysis.
Topics: Animals; Choline; Chronic Disease; Diagnosis, Differential; Disease Models, Animal; Lactic Acid; Lip | 2007 |
Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.
Topics: Animals; Arachidonic Acid; Cell Division; CHO Cells; Choline; Choline-Phosphate Cytidylyltransferase | 2001 |
Azaserine carcinogenesis: organ susceptibility change in rats fed a diet devoid of choline.
Topics: Animals; Azaserine; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Liver; Liver | 1978 |
Preneoplastic and neoplastic lesions in the pancreas of rats fed choline-devoid or choline-supplemented diets.
Topics: Animals; Choline; Choline Deficiency; Male; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; | 1991 |