Page last updated: 2024-10-16

choline and Overweight

choline has been researched along with Overweight in 13 studies

Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.

Research Excerpts

ExcerptRelevanceReference
"Betaine is highly individual in overweight people with diabetes."9.20Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015)
"Among a sample of adults with overweight and obesity, greater intake of choline and lutein+zeaxanthin was associated with faster performance on a cognitive flexibility task."8.12Dietary lutein plus zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity. ( Burd, NA; Dilger, RN; Edwards, CG; Erdman, JW; Holscher, HD; Khan, NA; Reeser, GE; Thompson, SV; Walk, AM, 2022)
"Choline is an important metabolite involved in phospholipids synthesis, including serum lipids, and is the immediate precursor of betaine."5.91Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults. ( Abbasi, MSP; Ardekani, AM; Gharebakhshi, F; Jafarzadeh, F; Manzouri, A; Nikrad, N; Tousi, AZ; Vahdat, S; Yazdani, Y, 2023)
"The choline treatments were control (no additional choline added, 1."5.72Dose-response relationship between dietary choline and serum lipid profile, energy expenditure, and respiratory quotient in overweight adult cats fed at maintenance energy requirements. ( Bakovic, M; Godfrey, H; Grant, CE; Kirby, G; Rankovic, A; Shoveller, AK; Verbrugghe, A, 2022)
"Our findings underscore the importance of changes in TMAO, choline and L-carnitine in improving insulin sensitivity during a weight-loss intervention for obese patients."5.30Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial. ( Bray, GA; DiDonato, JA; Heianza, Y; Li, X; Qi, L; Sacks, FM; Sun, D, 2019)
" We examined associations of weight loss diet-induced changes in a gut microbiota-related metabolite trimethylamine N-oxide (TMAO), and its precursors (choline and l-carnitine), with changes in bone mineral density (BMD) considering diabetes-related factors."5.30Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial. ( Bray, GA; Chen, Y; DiDonato, JA; Heianza, Y; LeBoff, MS; Li, X; Pei, X; Qi, L; Sacks, FM; Sun, D; Zhou, T, 2019)
"Betaine is highly individual in overweight people with diabetes."5.20Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015)
" Serious adverse events from supplements with these ingredients are rare and typically involve unusually high intakes."2.82Dietary Supplements for Weight Management: A Narrative Review of Safety and Metabolic Health Benefits. ( Blumberg, JB; Chen, O; Liska, DJ; Mah, E, 2022)
"Choline is an important metabolite involved in phospholipids synthesis, including serum lipids, and is the immediate precursor of betaine."1.91Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults. ( Abbasi, MSP; Ardekani, AM; Gharebakhshi, F; Jafarzadeh, F; Manzouri, A; Nikrad, N; Tousi, AZ; Vahdat, S; Yazdani, Y, 2023)
"The choline treatments were control (no additional choline added, 1."1.72Dose-response relationship between dietary choline and serum lipid profile, energy expenditure, and respiratory quotient in overweight adult cats fed at maintenance energy requirements. ( Bakovic, M; Godfrey, H; Grant, CE; Kirby, G; Rankovic, A; Shoveller, AK; Verbrugghe, A, 2022)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (30.77)24.3611
2020's9 (69.23)2.80

Authors

AuthorsStudies
Mah, E1
Chen, O1
Liska, DJ1
Blumberg, JB1
Rankovic, A2
Godfrey, H2
Grant, CE2
Shoveller, AK2
Bakovic, M2
Kirby, G2
Verbrugghe, A2
Poursalehi, D1
Lotfi, K1
Mirzaei, S1
Asadi, A1
Akhlaghi, M1
Saneei, P1
Abbasi, MSP1
Tousi, AZ1
Yazdani, Y1
Vahdat, S1
Gharebakhshi, F1
Nikrad, N1
Manzouri, A1
Ardekani, AM1
Jafarzadeh, F1
Zhu, C1
Sawrey-Kubicek, L1
Bardagjy, AS1
Houts, H1
Tang, X1
Sacchi, R1
Randolph, JM1
Steinberg, FM1
Zivkovic, AM1
Edwards, CG1
Walk, AM1
Thompson, SV1
Reeser, GE1
Dilger, RN1
Erdman, JW1
Burd, NA1
Holscher, HD1
Khan, NA1
Dos Santos Fechine, CPN1
Monteiro, MGCA1
Tavares, JF1
Souto, AL1
Luna, RCP1
da Silva, CSO1
da Silva, JA1
Dos Santos, SG1
de Carvalho Costa, MJ1
Persuhn, DC1
Młodzik-Czyżewska, MA1
Szwengiel, A1
Malinowska, AM1
Chmurzynska, A1
Heianza, Y2
Sun, D2
Li, X2
DiDonato, JA2
Bray, GA2
Sacks, FM2
Qi, L2
Zhou, T1
Chen, Y1
Pei, X1
LeBoff, MS1
McEntyre, CJ1
Lever, M1
Chambers, ST1
George, PM1
Slow, S1
Elmslie, JL1
Florkowski, CM1
Lunt, H1
Krebs, JD1
Gazdzinski, S1
Millin, R1
Kaiser, LG1
Durazzo, TC1
Mueller, SG1
Weiner, MW1
Meyerhoff, DJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Preventing Overweight Using Novel Dietary Strategies (Pounds Lost)[NCT00072995]811 participants Interventional2003-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for choline and Overweight

ArticleYear
Dietary Supplements for Weight Management: A Narrative Review of Safety and Metabolic Health Benefits.
    Nutrients, 2022, Apr-24, Volume: 14, Issue:9

    Topics: Antioxidants; Caffeine; Catechin; Choline; Dietary Supplements; Humans; Overweight; Plant Extracts;

2022

Trials

5 trials available for choline and Overweight

ArticleYear
Whole egg consumption increases plasma choline and betaine without affecting TMAO levels or gut microbiome in overweight postmenopausal women.
    Nutrition research (New York, N.Y.), 2020, Volume: 78

    Topics: Aged; Bacteria; Betaine; Choline; Cross-Over Studies; Diet; Eggs; Feces; Female; Gastrointestinal Mi

2020
Choline Metabolites, Hydroxybutyrate and HDL after Dietary Fiber Supplementation in Overweight/Obese Hypertensive Women: A Metabolomic Study.
    Nutrients, 2021, Apr-24, Volume: 13, Issue:5

    Topics: Adult; Choline; Dietary Fiber; Dietary Supplements; Female; Humans; Hydroxybutyrates; Hypertension;

2021
Gut microbiota metabolites, amino acid metabolites and improvements in insulin sensitivity and glucose metabolism: the POUNDS Lost trial.
    Gut, 2019, Volume: 68, Issue:2

    Topics: Adult; Amino Acids; Carnitine; Choline; Diet, Reducing; Female; Gastrointestinal Microbiome; Glucose

2019
Circulating Gut Microbiota Metabolite Trimethylamine N-Oxide (TMAO) and Changes in Bone Density in Response to Weight Loss Diets: The POUNDS Lost Trial.
    Diabetes care, 2019, Volume: 42, Issue:8

    Topics: Absorptiometry, Photon; Adult; Bone Density; Carnitine; Choline; Diabetes Mellitus, Type 2; Diet, Re

2019
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period.
    Annals of clinical biochemistry, 2015, Volume: 52, Issue:Pt 3

    Topics: Aged; Betaine; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Humans; Male;

2015

Other Studies

7 other studies available for choline and Overweight

ArticleYear
Dose-response relationship between dietary choline and serum lipid profile, energy expenditure, and respiratory quotient in overweight adult cats fed at maintenance energy requirements.
    Journal of animal science, 2022, Jul-01, Volume: 100, Issue:7

    Topics: Animals; Body Weight; Cat Diseases; Cats; Cholesterol; Choline; Diet; Energy Metabolism; Lipoprotein

2022
Association between methyl donor nutrients and metabolic health status in overweight and obese adolescents.
    Scientific reports, 2022, 10-11, Volume: 12, Issue:1

    Topics: Adolescent; Betaine; Body Mass Index; Choline; Cross-Sectional Studies; Female; Health Status; Human

2022
Serum metabolomic analysis of the dose-response effect of dietary choline in overweight male cats fed at maintenance energy requirements.
    PloS one, 2023, Volume: 18, Issue:1

    Topics: Animal Feed; Animals; Betaine; Body Weight; Cats; Choline; Diet; Male; Overweight

2023
Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults.
    BMC endocrine disorders, 2023, Mar-27, Volume: 23, Issue:1

    Topics: Adult; Betaine; Biomarkers; Cardiometabolic Risk Factors; Cholesterol; Choline; Diet; Eating; Humans

2023
Dietary lutein plus zeaxanthin and choline intake is interactively associated with cognitive flexibility in middle-adulthood in adults with overweight and obesity.
    Nutritional neuroscience, 2022, Volume: 25, Issue:7

    Topics: Adult; Biomarkers; Choline; Cognition; Diet; Humans; Lutein; Middle Aged; Obesity; Overweight; Zeaxa

2022
Comparison of Associations between One-Carbon Metabolism, Lipid Metabolism, and Fatty Liver Markers in Normal-Weight and Overweight People Aged 20-40 Years.
    Annals of nutrition & metabolism, 2021, Volume: 77, Issue:4

    Topics: Adult; Betaine; Carbon; Choline; Fatty Liver; Humans; Lipid Metabolism; Overweight; Phosphatidyletha

2021
BMI and neuronal integrity in healthy, cognitively normal elderly: a proton magnetic resonance spectroscopy study.
    Obesity (Silver Spring, Md.), 2010, Volume: 18, Issue:4

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Body Mass Index; Choline; Cognition; Creatine; Female; Front

2010
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