choline has been researched along with Oligodendroglioma in 21 studies
Oligodendroglioma: A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diffusion tensor imaging (DTI) and MR spectroscopy are noninvasive, quantitative tools for the preoperative assessment of gliomas with which the quantitative parameter fractional anisotropy (FA) and the concentration of neurometabolites N-acetylaspartate (NAA), choline (Cho), creatine (Cr) of the brain can be determined." | 3.73 | Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study. ( Ding, XQ; Fiehler, J; Goebell, E; Hagel, C; Heese, O; Kucinski, T; Nietz, S; Paustenbach, S; Westphal, M; Zeumer, H, 2006) |
| " Oligodendrogliomas had higher choline levels than astrocytomas." | 3.68 | [1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia]. ( Felber, SR, 1993) |
| "Primary brain tumors (PBT), in particular gliomas, are among the most difficult neoplasms to treat, necessitating good quality imaging to guide clinicians at many junctures." | 1.37 | Promising role of [18F] fluorocholine PET/CT vs [18F] fluorodeoxyglucose PET/CT in primary brain tumors-early experience. ( Lam, WW; Ng, DC; Ong, SC; See, SJ; Wong, WY; Yu, SW, 2011) |
| "The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)." | 1.37 | [Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011) |
| "Ten patients with untreated gliomas were examined on a 1." | 1.32 | Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas. ( Buslei, R; Fahlbusch, R; Ganslandt, O; Gruber, S; Moser, E; Nimsky, C; Stadlbauer, A, 2004) |
| "We examined 120 patients with brain tumors using a 1." | 1.31 | In vivo proton magnetic resonance spectroscopy of brain tumors. ( Fountas, KN; Gotsis, SD; Johnston, KW; Kapsalaki, EZ; Kapsalakis, JZ; Papadakis, N; Robinson, JS; Smisson , HF, 2000) |
| "Choline was elevated in the cellular portion of both tumors but decreased in the necrotic or cystic portions." | 1.29 | Localized in vivo 1H magnetic resonance spectroscopy and in vitro analyses of heterogeneous brain tumors. ( Booth, RA; Buchthal, SD; Chang, L; Cornford, M; Ernst, TM; Jenden, D; McBride, D; Miller, BL, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 5 (23.81) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourdillon, P | 1 |
| Hlaihel, C | 2 |
| Guyotat, J | 2 |
| Guillotton, L | 1 |
| Honnorat, J | 2 |
| Ducray, F | 1 |
| Cotton, F | 2 |
| Guilloton, L | 1 |
| Streichenberger, N | 1 |
| Lam, WW | 1 |
| Ng, DC | 1 |
| Wong, WY | 1 |
| Ong, SC | 1 |
| Yu, SW | 1 |
| See, SJ | 1 |
| Isobe, T | 1 |
| Akutsu, H | 1 |
| Yamamoto, T | 1 |
| Shiigai, M | 1 |
| Masumoto, T | 1 |
| Nakai, K | 1 |
| Takano, S | 1 |
| Anno, I | 1 |
| Matsumura, A | 1 |
| Rijpkema, M | 1 |
| Schuuring, J | 1 |
| van der Meulen, Y | 1 |
| van der Graaf, M | 1 |
| Bernsen, H | 1 |
| Boerman, R | 1 |
| van der Kogel, A | 1 |
| Heerschap, A | 1 |
| Vuori, K | 1 |
| Kankaanranta, L | 1 |
| Häkkinen, AM | 2 |
| Gaily, E | 1 |
| Valanne, L | 1 |
| Granström, ML | 1 |
| Joensuu, H | 1 |
| Blomstedt, G | 1 |
| Paetau, A | 2 |
| Lundbom, N | 2 |
| Stadlbauer, A | 1 |
| Moser, E | 1 |
| Gruber, S | 1 |
| Buslei, R | 1 |
| Nimsky, C | 1 |
| Fahlbusch, R | 1 |
| Ganslandt, O | 1 |
| Magalhaes, A | 1 |
| Godfrey, W | 1 |
| Shen, Y | 1 |
| Hu, J | 1 |
| Smith, W | 1 |
| Jenkinson, MD | 1 |
| Smith, TS | 1 |
| Joyce, K | 1 |
| Fildes, D | 1 |
| du Plessis, DG | 1 |
| Warnke, PC | 1 |
| Walker, C | 1 |
| Pulkkinen, J | 1 |
| Kauppinen, RA | 1 |
| Hiltunen, Y | 1 |
| Grand, S | 1 |
| Tropres, I | 1 |
| Hoffmann, D | 1 |
| Ziegler, A | 1 |
| Le Bas, JF | 1 |
| Lichy, MP | 1 |
| Bachert, P | 1 |
| Hamprecht, F | 1 |
| Weber, MA | 1 |
| Debus, J | 1 |
| Schulz-Ertner, D | 1 |
| Schlemmer, HP | 1 |
| Kauczor, HU | 1 |
| Goebell, E | 1 |
| Fiehler, J | 1 |
| Ding, XQ | 1 |
| Paustenbach, S | 1 |
| Nietz, S | 1 |
| Heese, O | 1 |
| Kucinski, T | 1 |
| Hagel, C | 1 |
| Westphal, M | 1 |
| Zeumer, H | 1 |
| Poduslo, SE | 1 |
| Miller, K | 1 |
| Jang, Y | 1 |
| Hagberg, G | 1 |
| Burlina, AP | 1 |
| Mader, I | 1 |
| Roser, W | 1 |
| Radue, EW | 1 |
| Seelig, J | 1 |
| Chang, L | 1 |
| McBride, D | 1 |
| Miller, BL | 1 |
| Cornford, M | 1 |
| Booth, RA | 1 |
| Buchthal, SD | 1 |
| Ernst, TM | 1 |
| Jenden, D | 1 |
| Felber, SR | 1 |
| Gupta, RK | 2 |
| Sinha, U | 2 |
| Cloughesy, TF | 2 |
| Alger, JR | 2 |
| Fountas, KN | 1 |
| Kapsalaki, EZ | 1 |
| Gotsis, SD | 1 |
| Kapsalakis, JZ | 1 |
| Smisson , HF | 1 |
| Johnston, KW | 1 |
| Robinson, JS | 1 |
| Papadakis, N | 1 |
| Garakian, J | 1 |
| Lazareff, J | 1 |
| Rubino, G | 1 |
| Rubino, L | 1 |
| Becker, DP | 1 |
| Vinters, HV | 1 |
| Henriksen, O | 1 |
| Wieslander, S | 1 |
| Gjerris, F | 1 |
| Jensen, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458] | 50 participants (Anticipated) | Observational | 2020-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for choline and Oligodendroglioma
| Article | Year |
|---|---|
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid | 2003 |
20 other studies available for choline and Oligodendroglioma
| Article | Year |
|---|---|
Prediction of anaplastic transformation in low-grade oligodendrogliomas based on magnetic resonance spectroscopy and 1p/19q codeletion status.
Topics: Adult; Aged; Aspartic Acid; Brain Neoplasms; Choline; Chromosome Deletion; Chromosomes, Human, Pair | 2015 |
Predictive value of multimodality MRI using conventional, perfusion, and spectroscopy MR in anaplastic transformation of low-grade oligodendrogliomas.
Topics: Adult; Aged; Brain Neoplasms; Cerebrovascular Circulation; Choline; Contrast Media; Creatine; Diffus | 2010 |
Promising role of [18F] fluorocholine PET/CT vs [18F] fluorodeoxyglucose PET/CT in primary brain tumors-early experience.
Topics: Brain Neoplasms; Choline; Fatal Outcome; Female; Fluorine Radioisotopes; Glioblastoma; Glioma; Human | 2011 |
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F | 2011 |
Low-grade gliomas and focal cortical developmental malformations: differentiation with proton MR spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Astrocytoma; Cerebral Cortex; Child; Choline; Creatine; Diagnosis, | 2004 |
Improved delineation of brain tumors: an automated method for segmentation based on pathologic changes of 1H-MRSI metabolites in gliomas.
Topics: Adult; Algorithms; Aspartic Acid; Astrocytoma; Automation; Biopsy; Brain Chemistry; Brain Mapping; B | 2004 |
Proton magnetic resonance spectroscopy of brain tumors correlated with pathology.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Choline; Creatin | 2005 |
MRS of oligodendroglial tumors: correlation with histopathology and genetic subtypes.
Topics: Adult; Aged; Allelic Imbalance; Astrocytoma; Brain Neoplasms; Choline; Chromosomes, Human, Pair 1; C | 2005 |
Independent component analysis to proton spectroscopic imaging data of human brain tumours.
Topics: Algorithms; Aspartic Acid; Astrocytoma; Brain Neoplasms; Cell Proliferation; Choline; Creatine; Glio | 2005 |
[Proton magnetic resonance spectroscopy (1H-MRS) for the diagnosis of brain tumors and the evaluation of treatment].
Topics: Acetates; Alanine; Amino Acids; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glutami | 2005 |
[Application of (1)H MR spectroscopic imaging in radiation oncology: choline as a marker for determining the relative probability of tumor progression after radiation of glial brain tumors].
Topics: Adult; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Chemotherapy, Adjuvant; Choline; Combined | 2006 |
Disarrangement of fiber tracts and decline of neuronal density correlate in glioma patients--a combined diffusion tensor imaging and 1H-MR spectroscopy study.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Astrocytoma; Brain; Brain Neoplasms; Cell Size; Choline; Cre | 2006 |
Comparison of lipids and lipid metabolism in a human glioma cell line, its clone, and oligodendroglia.
Topics: Acetates; Acetic Acid; Cell Line; Choline; Chromatography, Thin Layer; Clone Cells; Glioma; Glycolip | 1983 |
In vivo proton MR spectroscopy of human gliomas: definition of metabolic coordinates for multi-dimensional classification.
Topics: Adult; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Cluster Analysis; Creatine; Discriminan | 1995 |
Localized in vivo 1H magnetic resonance spectroscopy and in vitro analyses of heterogeneous brain tumors.
Topics: Adult; Brain Neoplasms; Choline; Creatine; Female; Glycerylphosphorylcholine; Humans; Hydrogen; Lact | 1995 |
[1H magnetic resonance spectroscopy in intracranial tumors and cerebral ischemia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Ischemia; Child; Child, Preschool; | 1993 |
Inverse correlation between choline magnetic resonance spectroscopy signal intensity and the apparent diffusion coefficient in human glioma.
Topics: Adult; Aged; Brain Neoplasms; Choline; Diffusion; Echo-Planar Imaging; Female; Follow-Up Studies; Fo | 1999 |
In vivo proton magnetic resonance spectroscopy of brain tumors.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Astrocytoma; Brain; Brain Abscess; Brain Neoplasms; Choline | 2000 |
Relationships between choline magnetic resonance spectroscopy, apparent diffusion coefficient and quantitative histopathology in human glioma.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Choline; Diffusion; Echo-Planar Imaging; Female; Follow-U | 2000 |
In vivo 1H-spectroscopy of human intracranial tumors at 1.5 tesla. Preliminary experience at a clinical installation.
Topics: Adult; Aged; Aspartic Acid; Astrocytoma; Brain Neoplasms; Choline; Creatine; Female; Humans; Lactate | 1991 |