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choline and Obsessive-Compulsive Disorder

choline has been researched along with Obsessive-Compulsive Disorder in 34 studies

Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.

Research Excerpts

ExcerptRelevanceReference
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."7.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)
"In this study, N-acetyl-aspartate, a putative marker of neuronal viability, creatine/phosphocreatine, and choline levels were measured in the lateral and medical subregions of the left and right thalami using a multislice proton magnetic resonance spectroscopic imaging sequence in 11 treatment-naive, nondepressed obsessive-compulsive disorder outpatients, 8-15 years old, and 11 case-matched control subjects."3.70Proton spectroscopic imaging of the thalamus in treatment-naive pediatric obsessive-compulsive disorder. ( Fitzgerald, KD; Moore, GJ; Paulson, LA; Rosenberg, DR; Stewart, CM, 2000)
"Erythrocyte and plasma choline parameters were compared in children (n = 63), aged 6-18 years, suffering from Tourette Syndrome (TS), their parents (n = 57), their unaffected siblings (n = 38), and an adult control group (n = 57)."3.68Controlled study of erythrocyte choline in Tourette syndrome. ( Hanin, I; Kopp, U; Sallee, FR, 1992)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's2 (5.88)18.2507
2000's16 (47.06)29.6817
2010's15 (44.12)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, R2
Fan, Q3
Zhang, Z2
Chen, Y2
Tong, S1
Li, Y2
Moon, CM1
Jeong, GW2
Zhu, Y1
Parmar, A1
Sharan, P1
Khandelwal, SK1
Agarwal, K1
Sharma, U1
Jagannathan, NR1
Weber, AM1
Soreni, N1
Stanley, JA1
Greco, A1
Mendlowitz, S1
Szatmari, P1
Schachar, R1
Mannasis, K1
Pires, P1
Swinson, R1
Noseworthy, MD1
Tükel, R2
Aydın, K2
Ertekin, E2
Özyıldırım, SŞ2
Taravari, V1
Barburoğlu, M1
Park, SE1
Choi, NG1
Ljungberg, M2
Nilsson, MKL1
Melin, K1
Jönsson, L2
Carlsson, A3
Forssell-Aronsson, E2
Ivarsson, T2
Carlsson, M1
Starck, G2
Fan, S1
Cath, DC1
van den Heuvel, OA1
van der Werf, YD1
Schöls, C1
Veltman, DJ1
Pouwels, PJW1
Nilsson, M1
Lundberg, S1
Ribbelin, S1
Ekholm, S1
Carlsson, ML1
Scherk, H2
Backens, M2
Zill, P1
Schneider-Axmann, T2
Wobrock, T1
Usher, J2
Reith, W2
Falkai, P2
Möller, HJ1
Bondy, B1
Gruber, O2
Atmaca, M1
Yildirim, H1
Ozdemir, H1
Koc, M1
Ozler, S1
Tezcan, E1
Kumar, V1
Chakrabarti, S1
Modi, M1
Sahoo, M1
Tan, L1
You, C1
Wang, J1
Ross, CA1
Wang, X1
Zhang, T1
Li, J1
Chen, K1
Xiao, Z1
Bédard, MJ1
Chantal, S1
Besiroglu, L1
Sozen, M1
Ozbebit, O1
Avcu, S1
Selvi, Y1
Bora, A1
Atli, A1
Unal, O1
Bulut, MD1
Lázaro, L1
Bargalló, N1
Andrés, S1
Falcón, C1
Morer, A1
Junqué, C1
Castro-Fornieles, J1
O'Neill, J1
Gorbis, E1
Feusner, JD1
Yip, JC1
Chang, S1
Maidment, KM1
Levitt, JG1
Salamon, N1
Ringman, JM1
Saxena, S1
Russell, A3
Cortese, B1
Lorch, E2
Ivey, J3
Banerjee, SP3
Moore, GJ5
Rosenberg, DR5
Smith, EA1
Rose, M2
Bhandari, R2
Alkan, A1
Kutlu, R1
Kocak, G1
Sigirci, A1
Emul, M1
Dogan, S1
Aslan, M1
Sarac, K1
Yakinci, C1
Mirza, Y1
Tang, J1
Smith, JM1
Boyd, C1
ZALLA, A1
Jang, JH1
Kwon, JS1
Jang, DP1
Moon, WJ1
Lee, JM1
Ha, TH1
Chung, EC1
Kim, IY1
Kim, SI1
Kitamura, H1
Shioiri, T1
Kimura, T1
Ohkubo, M1
Nakada, T1
Someya, T1
Oner, O1
Devrimci-Ozguven, H1
Oktem, F1
Yagmurlu, B1
Baskak, B1
Munir, KM1
Mohamed, MA1
Smith, MA1
Schlund, MW1
Nestadt, G1
Barker, PB1
Hoehn-Saric, R1
Kraft, S1
Kemmer, C1
Meyer, J1
Yücel, M1
Wood, SJ1
Wellard, RM1
Harrison, BJ1
Fornito, A1
Pujol, J1
Velakoulis, D1
Pantelis, C1
Ohara, K2
Isoda, H1
Suzuki, Y1
Takehara, Y1
Ochiai, M1
Takeda, H1
Igarashi, Y1
Fitzgerald, KD1
Paulson, LA1
Stewart, CM1
Amponsah, A1
Sullivan, A1
MacMillan, S1
Sallee, FR1
Kopp, U1
Hanin, I1

Trials

2 trials available for choline and Obsessive-Compulsive Disorder

ArticleYear
Localized functional neurochemical marker abnormalities in dorsolateral prefrontal cortex in pediatric obsessive-compulsive disorder.
    Journal of child and adolescent psychopharmacology, 2003, Volume: 13 Suppl 1

    Topics: Adolescent; Aspartic Acid; Biomarkers; Child; Choline; Creatine; Female; Humans; Image Interpretatio

2003
Brain MR spectroscopy in children with a history of rheumatic fever with a special emphasis on neuropsychiatric complications.
    European journal of radiology, 2004, Volume: 49, Issue:3

    Topics: Adolescent; Analysis of Variance; Aspartic Acid; Basal Ganglia; Child; Child, Preschool; Choline; Ch

2004

Other Studies

32 other studies available for choline and Obsessive-Compulsive Disorder

ArticleYear
White matter integrity correlates with choline level in dorsal anterior cingulate cortex of obsessive compulsive disorder patients: A combined DTI-MRS study.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2017, Volume: 2017

    Topics: Choline; Diffusion Tensor Imaging; Gyrus Cinguli; Humans; Obsessive-Compulsive Disorder; White Matte

2017
Associations of neurofunctional, morphometric and metabolic abnormalities with clinical symptom severity and recognition deficit in obsessive-compulsive disorder.
    Journal of affective disorders, 2018, Volume: 227

    Topics: Adult; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Creatine; Female; Glutami

2018
Anterior thalamic radiation structural and metabolic changes in obsessive-compulsive disorder: A combined DTI-MRS study.
    Psychiatry research. Neuroimaging, 2018, 07-30, Volume: 277

    Topics: Adolescent; Adult; Anisotropy; Choline; Diffusion Tensor Imaging; Female; Humans; Male; Middle Aged;

2018
Brain neurochemistry in unmedicated obsessive-compulsive disorder patients and effects of 12-week escitalopram treatment:
    Psychiatry and clinical neurosciences, 2019, Volume: 73, Issue:7

    Topics: Adolescent; Adult; Case-Control Studies; Caudate Nucleus; Choline; Citalopram; Female; Follow-Up Stu

2019
Proton magnetic resonance spectroscopy of prefrontal white matter in psychotropic naïve children and adolescents with obsessive-compulsive disorder.
    Psychiatry research, 2014, Apr-30, Volume: 222, Issue:1-2

    Topics: Adolescent; Child; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Mal

2014
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for reduced neuronal integrity in the anterior cingulate.
    Psychiatry research, 2014, Dec-30, Volume: 224, Issue:3

    Topics: Adult; Aspartic Acid; Caudate Nucleus; Choline; Creatine; Female; Gyrus Cinguli; Humans; Inositol; M

2014
1H-magnetic resonance spectroscopy in obsessive-compulsive disorder: effects of 12 weeks of sertraline treatment on brain metabolites.
    European archives of psychiatry and clinical neuroscience, 2015, Volume: 265, Issue:3

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Follow-Up Studies; Hum

2015
Metabolic abnormality in the right dorsolateral prefrontal cortex in patients with obsessive-compulsive disorder: proton magnetic resonance spectroscopy.
    Acta neuropsychiatrica, 2017, Volume: 29, Issue:3

    Topics: Adult; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Aci

2017
1H magnetic resonance spectroscopy evidence for occipital involvement in treatment-naive paediatric obsessive-compulsive disorder.
    Acta neuropsychiatrica, 2017, Volume: 29, Issue:3

    Topics: Adolescent; Aspartic Acid; Brain; Child; Choline; Female; Humans; Inositol; Male; Obsessive-Compulsi

2017
Abnormalities in metabolite concentrations in tourette's disorder and obsessive-compulsive disorder-A proton magnetic resonance spectroscopy study.
    Psychoneuroendocrinology, 2017, Volume: 77

    Topics: Adult; Choline; Female; Glutamic Acid; Glutamine; Gyrus Cinguli; Humans; Male; Middle Aged; Obsessiv

2017
A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:7

    Topics: Adult; Aspartic Acid; Brain; Brain Mapping; Case-Control Studies; Choline; Creatine; Female; Glutami

2008
SNAP-25 genotype influences NAA/Cho in left hippocampus.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:11

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; DNA; Female; Genotype; Hippocampus; Humans; Magneti

2008
Neurochemistry of the hippocampus in patients with obsessive-compulsive disorder.
    Psychiatry and clinical neurosciences, 2009, Volume: 63, Issue:4

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Creatine; Female; Functional Laterality;

2009
Late-onset obsessive compulsive disorder associated with possible gliomatosis cerebri.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Aged; Anticonvulsants; Aspartic Acid; Brain Neoplasms; Choline; Corpus Callosum; Dominance, Cerebral

2009
Increased N-Acetylaspartate/creatine ratio in the medial prefrontal cortex among unmedicated obsessive-compulsive disorder patients.
    Psychiatry and clinical neurosciences, 2010, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Diagnostic and Statistical Manual of Mental Dis

2010
Brain magnetic resonance spectroscopy in obsessive-compulsive disorder: the importance of considering subclinical symptoms of anxiety and depression.
    Psychiatry research, 2011, Apr-30, Volume: 192, Issue:1

    Topics: Adult; Anxiety; Aspartic Acid; Brain; Brain Mapping; Choline; Creatine; Depression; Female; Function

2011
The involvement of distinct neural systems in patients with obsessive-compulsive disorder with autogenous and reactive obsessions.
    Acta psychiatrica Scandinavica, 2011, Volume: 124, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Creatine; Diagnostic and Statistical Manual of Mental Disorders; Drug

2011
Proton magnetic resonance spectroscopy in pediatric obsessive-compulsive disorder: longitudinal study before and after treatment.
    Psychiatry research, 2012, Jan-30, Volume: 201, Issue:1

    Topics: Adolescent; Aspartic Acid; Behavior Therapy; Brain; Child; Choline; Creatine; Female; Follow-Up Stud

2012
Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder.
    Journal of psychiatric research, 2013, Volume: 47, Issue:4

    Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Cognitive Behavioral Therapy; Dipeptides

2013
Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study.
    Biological psychiatry, 2003, Dec-15, Volume: 54, Issue:12

    Topics: Adolescent; Analysis of Variance; Brain Chemistry; Brain Mapping; Case-Control Studies; Child; Choli

2003
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2004, Volume: 43, Issue:9

    Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Ac

2004
[Choline therapy in psychasthenia].
    Rivista di patologia nervosa e mentale, 1950, Volume: 71, Issue:1

    Topics: Choline; Humans; Neurasthenia; Neurotic Disorders; Obsessive-Compulsive Disorder

1950
A proton MRSI study of brain N-acetylaspartate level after 12 weeks of citalopram treatment in drug-naive patients with obsessive-compulsive disorder.
    The American journal of psychiatry, 2006, Volume: 163, Issue:7

    Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Choline; Citalopram; Creatine; Female; Frontal Lobe; G

2006
Parietal white matter abnormalities in obsessive-compulsive disorder: a magnetic resonance spectroscopy study at 3-Tesla.
    Acta psychiatrica Scandinavica, 2006, Volume: 114, Issue:2

    Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy

2006
Proton MR spectroscopy: higher right anterior cingulate N-acetylaspartate/choline ratio in Asperger syndrome compared with healthy controls.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:8

    Topics: Adolescent; Adult; Aspartic Acid; Asperger Syndrome; Choline; Diagnostic and Statistical Manual of M

2007
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: a pilot investigation comparing treatment responders and non-responders.
    Psychiatry research, 2007, Nov-15, Volume: 156, Issue:2

    Topics: Adult; Aspartic Acid; Basal Ganglia; Choline; Creatine; Dominance, Cerebral; Energy Metabolism; Fema

2007
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 2

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Memb

2009
Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:6

    Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli

2008
Proton magnetic resonance spectroscopy of lenticular nuclei in obsessive-compulsive disorder.
    Psychiatry research, 1999, Dec-20, Volume: 92, Issue:2-3

    Topics: Adult; Analysis of Variance; Aspartame; Basal Ganglia; Choline; Corpus Striatum; Creatine; Female; H

1999
Proton spectroscopic imaging of the thalamus in treatment-naive pediatric obsessive-compulsive disorder.
    Biological psychiatry, 2000, Feb-01, Volume: 47, Issue:3

    Topics: Adolescent; Aspartic Acid; Brain Mapping; Case-Control Studies; Cerebral Cortex; Child; Choline; Cor

2000
Increased medial thalamic choline in pediatric obsessive-compulsive disorder as detected by quantitative in vivo spectroscopic imaging.
    Journal of child neurology, 2001, Volume: 16, Issue:9

    Topics: Adolescent; Aspartic Acid; Brain Mapping; Case-Control Studies; Child; Choline; Creatine; Cytosol; D

2001
Controlled study of erythrocyte choline in Tourette syndrome.
    Biological psychiatry, 1992, Jun-15, Volume: 31, Issue:12

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Choline; Drug Therapy, Combination

1992