choline has been researched along with Niemann-Pick Diseases in 9 studies
Niemann-Pick Diseases: A group of autosomal recessive disorders in which harmful quantities of lipids accumulate in the viscera and the central nervous system. They can be caused by deficiencies of enzyme activities (SPHINGOMYELIN PHOSPHODIESTERASE) or defects in intracellular transport, resulting in the accumulation of SPHINGOMYELINS and CHOLESTEROL. There are various subtypes based on their clinical and genetic differences.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Choline is an essential nutrient that must be obtained from the diet and its deficiency promotes fatty liver disease in a process dependent on ASM activity." | 1.91 | Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency. ( Casas, J; Gaudioso, Á; Ledesma, MD; Moreno-Huguet, P; Schuchman, EH, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Gaudioso, Á | 1 |
| Moreno-Huguet, P | 1 |
| Casas, J | 1 |
| Schuchman, EH | 1 |
| Ledesma, MD | 1 |
| Spence, MW | 1 |
| Clarke, JT | 1 |
| Cook, HW | 1 |
| Maziere, JC | 1 |
| Maziere, C | 1 |
| Mora, L | 1 |
| Routier, JD | 1 |
| Polonovski, J | 1 |
| Gal, AE | 2 |
| Brady, RO | 2 |
| Barranger, JA | 1 |
| Pentchev, PG | 2 |
| Tedeschi, G | 1 |
| Bonavita, S | 1 |
| Barton, NW | 1 |
| Betolino, A | 1 |
| Frank, JA | 1 |
| Patronas, NJ | 1 |
| Alger, JR | 1 |
| Schiffmann, R | 1 |
| Patrick, AD | 1 |
| Young, E | 1 |
| Kleijer, WJ | 1 |
| Niermeijer, MF | 1 |
| Den Tandt, WR | 1 |
| Jaeken, J | 1 |
| Leroy, JG | 1 |
| Eggermont, E | 1 |
| Hibbert, SR | 1 |
| Strasberg, PM | 1 |
| Callahan, JW | 1 |
9 other studies available for choline and Niemann-Pick Diseases
| Article | Year |
|---|---|
Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency.
Topics: Animals; Choline; Diet; Disease Models, Animal; Mice; Mice, Knockout; Niemann-Pick Disease, Type A; | 2023 |
Pathways of sphingomyelin metabolism in cultured fibroblasts from normal and sphingomyelin lipidosis subjects.
Topics: Carbon Radioisotopes; Cells, Cultured; Choline; Fibroblasts; Humans; Kinetics; Male; Niemann-Pick Di | 1983 |
In situ degradation of sphingomyelin by cultured normal fibroblasts and fibroblasts from patients with Niemann-Pick disease type A and C.
Topics: Cells, Cultured; Choline; Fibroblasts; Homozygote; Humans; Niemann-Pick Diseases; Sphingomyelins | 1982 |
The diagnosis of type A and type B Niemann Pick disease and detection of carriers using leukocytes and a chromogenic analogue of sphingomyelin.
Topics: Choline; Genetic Carrier Screening; Humans; Leukocytes; Niemann-Pick Diseases; Nitrophenols; Phospho | 1980 |
Proton magnetic resonance spectroscopic imaging in the clinical evaluation of patients with Niemann-Pick type C disease.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Caudate Nucleus; Child; Choline; Creatine; Female; Frontal | 1998 |
Prenatal diagnosis of Niemann-Pick disease type A using chromogenic substrate.
Topics: Amniotic Fluid; Choline; Female; Fibroblasts; Humans; Niemann-Pick Diseases; Phosphorylcholine; Preg | 1977 |
A micromethod for sphingomyelinase assay using a chromogenic artificial substrate. Its use in the diagnosis of Niemann-Pick disease.
Topics: Adolescent; Child; Child, Preschool; Choline; Female; Fibroblasts; Humans; Male; Methods; Niemann-Pi | 1979 |
A practical chromogenic procedure for the detection of homozygotes and heterozygous carriers of Niemann-Pick disease.
Topics: Amniotic Fluid; Cells, Cultured; Cerebrosides; Choline; Clinical Enzyme Tests; Fibroblasts; Glucosyl | 1975 |
Lysosphingolipids and mitochondrial function. II. Deleterious effects of sphingosylphosphorylcholine.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Calcium; Choline; Erythrocytes; Hemolysi | 1988 |