choline has been researched along with Niemann-Pick Disease, Type A in 1 studies
Niemann-Pick Disease, Type A: The classic infantile form of Niemann-Pick Disease, caused by mutation in SPHINGOMYELIN PHOSPHODIESTERASE. It is characterized by accumulation of SPHINGOMYELINS in the cells of the MONONUCLEAR PHAGOCYTE SYSTEM and other cell throughout the body leading to cell death. Clinical signs include JAUNDICE, hepatosplenomegaly, and severe brain damage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Choline is an essential nutrient that must be obtained from the diet and its deficiency promotes fatty liver disease in a process dependent on ASM activity." | 1.91 | Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency. ( Casas, J; Gaudioso, Á; Ledesma, MD; Moreno-Huguet, P; Schuchman, EH, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaudioso, Á | 1 |
| Moreno-Huguet, P | 1 |
| Casas, J | 1 |
| Schuchman, EH | 1 |
| Ledesma, MD | 1 |
1 other study available for choline and Niemann-Pick Disease, Type A
| Article | Year |
|---|---|
Modulation of Dietary Choline Uptake in a Mouse Model of Acid Sphingomyelinase Deficiency.
Topics: Animals; Choline; Diet; Disease Models, Animal; Mice; Mice, Knockout; Niemann-Pick Disease, Type A; | 2023 |