choline has been researched along with Neoplasms in 127 studies
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The available data indicate that DEA induces mouse liver tumors by a non-genotoxic mode of action that involves its ability to cause choline deficiency." | 8.82 | Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action. ( Kamendulis, LM; Leung, HW; Stott, WT, 2005) |
| " We report the case of 30-year-old woman with secondary hyperparathyroidism due to severe chronic kidney diseases who underwent [18F]F-choline PET/CT scan for localization of the hyperfunctioning parathyroid gland before surgical treatment." | 8.31 | Detection of brown tumors by [18F]F-choline PET/CT performed in a patient with secondary hyperparathyroidism. ( Huic, D; Rogic, I, 2023) |
| "18F-choline uptake by inflammation was lower than that of 2DG in the tissue distribution study, and 18F-choline uptake by abscess wall was significantly lower than that of 2DG in the autoradiography study." | 7.73 | Comparison of 18F-fluoromethylcholine and 2-deoxy-D-glucose in the distribution of tumor and inflammation. ( Fukuda, H; Furumoto, S; Ishiwata, K; Iwata, R; Kawamura, K; Kubota, K, 2006) |
| "Choline was discovered to be an essential nutrient for some humans approximately one decade ago." | 6.48 | Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones. ( Zeisel, SH, 2012) |
| " The fluorine-18 ((18)F)-labeled choline derivative fluorocholine (FCH) in particular has demonstrated potential utility for imaging of a variety of neoplasms, including those of the breast, prostate, liver, and brain." | 4.84 | Cancer imaging with fluorine-18-labeled choline derivatives. ( Coel, MN; DeGrado, TR; Gutman, F; Kwee, SA; Talbot, JN, 2007) |
| " The available data indicate that DEA induces mouse liver tumors by a non-genotoxic mode of action that involves its ability to cause choline deficiency." | 4.82 | Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action. ( Kamendulis, LM; Leung, HW; Stott, WT, 2005) |
| "Choline deficiency causes hepatocyte proliferation, apoptosis and transformation." | 4.79 | Choline. A nutrient that is involved in the regulation of cell proliferation, cell death, and cell transformation. ( Zeisel, SH, 1996) |
| " We report the case of 30-year-old woman with secondary hyperparathyroidism due to severe chronic kidney diseases who underwent [18F]F-choline PET/CT scan for localization of the hyperfunctioning parathyroid gland before surgical treatment." | 4.31 | Detection of brown tumors by [18F]F-choline PET/CT performed in a patient with secondary hyperparathyroidism. ( Huic, D; Rogic, I, 2023) |
| "In vivo magnetic resonance spectroscopy (MRS) studies of glial brain tumours reported that higher grade of astrocytoma is associated with increased level of choline-containing compounds (Cho) and decreased levels of N-acetylaspartate (NAA) and creatine and phosphocreatine (Cr)." | 3.73 | In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy. ( Belan, V; Béres, A; De Riggo, J; Dobrota, D; Galanda, M; Likavcanová, K; Liptaj, T; Mlynárik, V; Prónayová, N, 2005) |
| "18F-choline uptake by inflammation was lower than that of 2DG in the tissue distribution study, and 18F-choline uptake by abscess wall was significantly lower than that of 2DG in the autoradiography study." | 3.73 | Comparison of 18F-fluoromethylcholine and 2-deoxy-D-glucose in the distribution of tumor and inflammation. ( Fukuda, H; Furumoto, S; Ishiwata, K; Iwata, R; Kawamura, K; Kubota, K, 2006) |
| "Cancer is the second leading cause of death in the world." | 3.01 | Association between Levels of Trimethylamine N-Oxide and Cancer: A Systematic Review and Meta-Analysis. ( Arabpour, Z; Hasani, M; Khodabakhshi, A; Monfared, V; Vahid, F, 2023) |
| "Choline levels were not associated with cancer incidence in a meta-analysis of cohort studies." | 2.61 | Association of choline and betaine levels with cancer incidence and survival: A meta-analysis. ( Cho, E; Lee, JE; Youn, J, 2019) |
| "To date, the majority of cancer-related studies have focused on phosphocholine and the Kennedy pathway, which constitutes the biosynthesis pathway for membrane phosphatidylcholine." | 2.61 | Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer. ( Adelaja, O; Ayyappan, V; Cai, R; Cheng, M; Glunde, K; Sonkar, K; Tressler, CM, 2019) |
| "Further clinical evaluation for most cancers is still needed, possibly in association to MRI." | 2.58 | How to use PET/CT in the evaluation of response to radiotherapy. ( Decazes, P; Dubray, B; Thureau, S; Vera, P, 2018) |
| "92) through a dose-response analysis." | 2.53 | Choline and betaine consumption lowers cancer risk: a meta-analysis of epidemiologic studies. ( Du, H; Du, M; Li, X; Ren, A; Shu, Y; Sun, S; Wang, W; Zhu, L, 2016) |
| "Besides prostate cancer, other possible uses of choline are related to its ability to indirectly evaluate the cell proliferation as a measure of the synthesis of lipids required for cell membrane." | 2.52 | Applications of PET imaging with radiolabelled choline (11C/18F-choline). ( Chiti, A; Kirienko, M; Lopci, E; Sollini, M; Versari, A, 2015) |
| "The aberrant choline metabolism in cancer cells is strongly correlated with their malignant progression." | 2.50 | Choline transporter-like proteins CTLs/SLC44 family as a novel molecular target for cancer therapy. ( Inazu, M, 2014) |
| "Musculoskeletal tumors comprise a multitude of tumor entities with different grades of malignancy, biological behavior, and therapeutic options." | 2.50 | PET tracers in musculoskeletal disease beyond FDG. ( Benz, MR; Buck, AK; Herrmann, K; Pomykala, KL; Wieder, HA, 2014) |
| "Choline PET has a role in the diagnosis of malignancies." | 2.50 | Fluorocholine PET/computed tomography: physiologic uptake, benign findings, and pitfalls. ( Beheshti, M; Bomanji, JB; Haroon, A; Langsteger, W, 2014) |
| "Brain tumors were evaluated in 15 articles, head and neck tumors in 6, thoracic tumors (including lung and mediastinal neoplasms) in 14, liver tumors (including hepatocellular carcinoma) in 5, gynecologic malignancies (including breast tumors) in 5, bladder and upper urinary tract tumors in 5, and musculoskeletal tumors in 7." | 2.48 | The role of positron emission tomography using carbon-11 and fluorine-18 choline in tumors other than prostate cancer: a systematic review. ( Calcagni, ML; Di Franco, D; Giordano, A; Giovannini, E; Picchio, M; Rufini, V; Treglia, G, 2012) |
| "Choline was discovered to be an essential nutrient for some humans approximately one decade ago." | 2.48 | Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones. ( Zeisel, SH, 2012) |
| " As conventional anatomically based pharmacological endpoints may be inadequate to monitor the tumor response to these targeted treatments, the identification and use of more appropriate, noninvasive pharmacodynamic biomarkers appear to be crucial to optimize the design, dosage and schedule of these novel therapeutic approaches." | 2.47 | MR evaluation of response to targeted treatment in cancer cells. ( Canese, R; Canevari, S; Iorio, E; Pisanu, ME; Podo, F; Ricci, A, 2011) |
| "We review its use in cancer diagnosis, staging, restaging, and assessment of response to treatment." | 2.47 | Metabolic positron emission tomography imaging in cancer detection and therapy response. ( Lee, D; Shim, H; Zhu, A, 2011) |
| "Developing rational targeted cancer drugs requires the implementation of pharmacodynamic (PD), preferably non-invasive, biomarkers to aid response assessment and patient follow-up." | 2.46 | Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy. ( Al-Saffar, NM; Beloueche-Babari, M; Chung, YL; Falck-Miniotis, M; Leach, MO, 2010) |
| " Such a relation is biologically plausible because ethanol impedes the bioavailability of dietary folate and is known to inhibit select folate-dependent biochemical reactions." | 2.43 | Effects of alcohol on folate metabolism: implications for carcinogenesis. ( Choi, SW; Mason, JB, 2005) |
| "The choline metabolite profile of tumors and cancer cells is characterized by an elevation of phosphocholine and total choline-containing compounds." | 2.43 | Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism. ( Glunde, K; Serkova, NJ, 2006) |
| "Several lines of evidence indicate that cancers might develop secondary to abnormalities in protein kinase C-mediated signal transduction." | 2.38 | Choline: an important nutrient in brain development, liver function and carcinogenesis. ( Zeisel, SH, 1992) |
| "Choline is an essential nutrient for mammalian cells." | 1.72 | Metabolic Labeling-Based Chemoproteomics Establishes Choline Metabolites as Protein Function Modulators. ( Dixit, A; Jose, GP; Kalia, J; Shanbhag, C; Tagad, N, 2022) |
| "We aimed to evaluate anticancer and antimicrobial activity of lipid-like choline derivatives modified via simultaneous introduction of tetrahydro(iso)quinoline based pharmacophore system at nitrogen atom and long chain alkyl substituent at oxygen atom." | 1.46 | N-Heterocyclic choline analogues based on 1,2,3,4-tetrahydro(iso)quinoline scaffold with anticancer and anti-infective dual action. ( Geronikaki, A; Makarenkova, G; Nikolajeva, V; Segal, I; Shestakova, I; Zablotskaya, A, 2017) |
| "Delirium is associated with a host of negative outcomes, including increased risk of mortality, longer hospital stay, and poor long-term cognitive function." | 1.37 | Proton Magnetic Resonance Spectroscopy in adult cancer patients with delirium. ( Beglinger, LJ; Capizzano, AA; Gingrich, R; Magnotta, VA; Mills, JA; Vik, SM; Weckmann, MT; Yager, JR, 2011) |
| "Choline PET has the potential to determine whether a PDT-treated tumor responds to treatment within 48 h after therapy." | 1.36 | Choline PET for monitoring early tumor response to photodynamic therapy. ( Chiu, SM; Fei, B; Wang, H; Wu, C, 2010) |
| "The presence of the NCX antigen in the cancer cells was proved by Western blotting, flow cytometry and confocal laser scanning microscopy." | 1.34 | Na+/Ca2+ exchanger inhibitors modify the accumulation of tumor-diagnostic PET tracers in cancer cells. ( Balkay, L; Friedlander, E; Krasznai, Z; Márián, T; Németh, E; Szabó, A; Szabó-Péli, J; Trón, L; Veress, G, 2007) |
| "[11C]Choline is a potential tracer to detect tumors, especially brain and prostate cancers." | 1.32 | Radiolabeled choline as a proliferation marker: comparison with radiolabeled acetate. ( Fujibayashi, Y; Furukawa, T; Obata, A; Waki, A; Yonekura, Y; Yoshimoto, M, 2004) |
| "Several (31)P MRS studies in tumors in vivo have shown that levels of phosphocholine (PC) and other phosphomonoesters (PME) and phosphodiesters (PDE) are useful prognostic or early-response indicators." | 1.32 | Comparison of polarization transfer sequences for enhancement of signals in clinical 31P MRS studies. ( Leach, MO; Mancini, L; Payne, GS, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (25.98) | 18.7374 |
| 1990's | 12 (9.45) | 18.2507 |
| 2000's | 27 (21.26) | 29.6817 |
| 2010's | 43 (33.86) | 24.3611 |
| 2020's | 12 (9.45) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, Y | 1 |
| Zhou, W | 1 |
| Han, Y | 1 |
| Wu, H | 1 |
| Watson, GA | 1 |
| Sanz-Garcia, E | 1 |
| Zhang, WJ | 1 |
| Liu, ZA | 1 |
| Yang, SC | 1 |
| Wang, B | 1 |
| Liu, S | 1 |
| Kubli, S | 1 |
| Berman, H | 1 |
| Pfister, T | 1 |
| Genta, S | 1 |
| Spreafico, A | 1 |
| Hansen, AR | 1 |
| Bedard, PL | 1 |
| Lheureux, S | 1 |
| Abdul Razak, A | 1 |
| Cescon, D | 1 |
| Butler, MO | 1 |
| Xu, W | 1 |
| Mak, TW | 1 |
| Siu, LL | 1 |
| Chen, E | 1 |
| Dixit, A | 1 |
| Jose, GP | 1 |
| Shanbhag, C | 1 |
| Tagad, N | 1 |
| Kalia, J | 1 |
| Khodabakhshi, A | 1 |
| Monfared, V | 1 |
| Arabpour, Z | 1 |
| Vahid, F | 1 |
| Hasani, M | 1 |
| Luque-Navarro, PM | 2 |
| Carrasco-Jiménez, MP | 2 |
| Goracci, L | 2 |
| Paredes, JM | 2 |
| Espinar-Barranco, L | 2 |
| Valverde-Pozo, J | 2 |
| Torretta, A | 2 |
| Parisini, E | 2 |
| Mariotto, E | 2 |
| Marchioro, C | 2 |
| Laso, A | 2 |
| Marco, C | 2 |
| Viola, G | 2 |
| Lanari, D | 2 |
| López Cara, LC | 2 |
| Tacconi, E | 1 |
| Palma, G | 1 |
| De Biase, D | 1 |
| Luciano, A | 1 |
| Barbieri, M | 1 |
| de Nigris, F | 1 |
| Bruzzese, F | 1 |
| Rogic, I | 1 |
| Huic, D | 1 |
| Onono, FO | 1 |
| Morris, AJ | 1 |
| Lu, G | 1 |
| Zuo, L | 1 |
| Zhang, J | 1 |
| Zhu, H | 1 |
| Zhuang, W | 1 |
| Wei, W | 1 |
| Xie, HY | 1 |
| Tahara, Y | 1 |
| Morita, K | 1 |
| Wakabayashi, R | 1 |
| Kamiya, N | 1 |
| Goto, M | 1 |
| Mbous, YP | 1 |
| Hayyan, M | 1 |
| Wong, WF | 1 |
| Hayyan, A | 1 |
| Looi, CY | 1 |
| Hashim, MA | 1 |
| Iorio, E | 2 |
| Podo, F | 2 |
| Leach, MO | 4 |
| Koutcher, J | 1 |
| Blankenberg, FG | 2 |
| Norfray, JF | 2 |
| Ribeiro, TH | 1 |
| S, R | 1 |
| Castro, AC | 1 |
| Paulino, E | 1 |
| Mamede, M | 1 |
| Zablotskaya, A | 1 |
| Segal, I | 1 |
| Geronikaki, A | 1 |
| Shestakova, I | 1 |
| Nikolajeva, V | 1 |
| Makarenkova, G | 1 |
| Decazes, P | 1 |
| Thureau, S | 1 |
| Dubray, B | 1 |
| Vera, P | 1 |
| Youn, J | 1 |
| Cho, E | 1 |
| Lee, JE | 1 |
| Hoffman, RM | 2 |
| Kokkinakis, DM | 1 |
| Frenkel, EP | 1 |
| Hedtke, V | 1 |
| Bakovic, M | 1 |
| Sonkar, K | 1 |
| Ayyappan, V | 1 |
| Tressler, CM | 1 |
| Adelaja, O | 1 |
| Cai, R | 1 |
| Cheng, M | 1 |
| Glunde, K | 7 |
| Jagannathan, NR | 1 |
| Inazu, M | 1 |
| Wieder, HA | 1 |
| Pomykala, KL | 1 |
| Benz, MR | 1 |
| Buck, AK | 1 |
| Herrmann, K | 1 |
| Antunovic, L | 1 |
| Rodari, M | 1 |
| Rossi, P | 1 |
| Chiti, A | 2 |
| Beheshti, M | 1 |
| Haroon, A | 1 |
| Bomanji, JB | 1 |
| Langsteger, W | 1 |
| Smyth, T | 1 |
| Kullberg, M | 1 |
| Malik, N | 1 |
| Smith-Jones, P | 1 |
| Graner, MW | 1 |
| Anchordoquy, TJ | 1 |
| Kirienko, M | 1 |
| Sollini, M | 1 |
| Lopci, E | 2 |
| Versari, A | 1 |
| Penet, MF | 1 |
| Jiang, L | 4 |
| Jacobs, MA | 2 |
| Bhujwalla, ZM | 3 |
| Wang, Y | 1 |
| Li, S | 1 |
| Feng, L | 1 |
| Nie, C | 1 |
| Liu, L | 1 |
| Lv, F | 1 |
| Wang, S | 1 |
| Corrigan, AJ | 1 |
| Schleyer, PJ | 1 |
| Cook, GJ | 2 |
| Doyle-Lindrud, S | 1 |
| Sun, S | 1 |
| Li, X | 1 |
| Ren, A | 1 |
| Du, M | 1 |
| Du, H | 1 |
| Shu, Y | 1 |
| Zhu, L | 1 |
| Wang, W | 1 |
| Chen, Q | 1 |
| Chu, T | 1 |
| Pantaleo, MA | 1 |
| Nannini, M | 1 |
| Castellucci, P | 1 |
| Maleddu, A | 1 |
| Lodi, F | 1 |
| Nanni, C | 4 |
| Allegri, V | 1 |
| Astorino, M | 1 |
| Brandi, G | 1 |
| Di Battista, M | 1 |
| Boschi, S | 1 |
| Fanti, S | 4 |
| Biasco, G | 1 |
| JAFFE, WG | 1 |
| Lowndes, SA | 1 |
| Adams, A | 1 |
| Timms, A | 1 |
| Fisher, N | 1 |
| Smythe, J | 1 |
| Watt, SM | 1 |
| Joel, S | 1 |
| Donate, F | 1 |
| Hayward, C | 1 |
| Reich, S | 1 |
| Middleton, M | 1 |
| Mazar, A | 1 |
| Harris, AL | 1 |
| Gauthier, H | 1 |
| Beloueche-Babari, M | 2 |
| Chung, YL | 1 |
| Al-Saffar, NM | 1 |
| Falck-Miniotis, M | 1 |
| Fei, B | 1 |
| Wang, H | 1 |
| Wu, C | 1 |
| Chiu, SM | 1 |
| Fantini, L | 1 |
| Nicolini, S | 1 |
| Mertens, K | 1 |
| Slaets, D | 1 |
| Lambert, B | 1 |
| Acou, M | 1 |
| De Vos, F | 1 |
| Goethals, I | 1 |
| Mao, J | 1 |
| Jiang, B | 1 |
| Liu, M | 1 |
| Mao, XA | 1 |
| TATUM, EL | 1 |
| RITCHEY, MG | 1 |
| COPELAND, DH | 1 |
| SALMON, WD | 1 |
| Yager, JR | 1 |
| Magnotta, VA | 1 |
| Mills, JA | 1 |
| Vik, SM | 1 |
| Weckmann, MT | 1 |
| Capizzano, AA | 1 |
| Gingrich, R | 1 |
| Beglinger, LJ | 1 |
| Zhu, A | 2 |
| Lee, D | 1 |
| Shim, H | 2 |
| Canevari, S | 1 |
| Canese, R | 1 |
| Pisanu, ME | 1 |
| Ricci, A | 1 |
| Moestue, SA | 1 |
| Gribbestad, IS | 1 |
| Workman, P | 1 |
| Zeisel, SH | 7 |
| Ronen, SM | 1 |
| Witney, TH | 1 |
| Alam, IS | 1 |
| Turton, DR | 1 |
| Smith, G | 1 |
| Carroll, L | 1 |
| Brickute, D | 1 |
| Twyman, FJ | 1 |
| Nguyen, QD | 1 |
| Tomasi, G | 1 |
| Awais, RO | 1 |
| Aboagye, EO | 1 |
| Davila, M | 1 |
| Candiota, AP | 1 |
| Pumarola, M | 1 |
| Arus, C | 1 |
| Marcus, DM | 1 |
| Shu, HK | 1 |
| Harris, DT | 1 |
| Treglia, G | 1 |
| Giovannini, E | 1 |
| Di Franco, D | 1 |
| Calcagni, ML | 1 |
| Rufini, V | 1 |
| Picchio, M | 1 |
| Giordano, A | 1 |
| Parashar, B | 1 |
| Wernicke, AG | 1 |
| Rice, S | 1 |
| Osborne, J | 1 |
| Singh, P | 1 |
| Nori, D | 1 |
| Vallabhajosula, S | 2 |
| Goldsmith, S | 1 |
| Chao, KS | 1 |
| Garcia, C | 1 |
| Gebhart, G | 1 |
| Flamen, P | 1 |
| Wijnen, JP | 1 |
| Marchan, R | 1 |
| Lesjak, MS | 1 |
| Stewart, JD | 1 |
| Winter, R | 1 |
| Seeliger, J | 1 |
| Hengstler, JG | 1 |
| Luo, Z | 1 |
| Tikekar, RV | 1 |
| Samadzadeh, KM | 1 |
| Nitin, N | 1 |
| Titov, VN | 1 |
| Lisitsyn, DM | 1 |
| Mancini, L | 1 |
| Payne, GS | 1 |
| KRAUS, HH | 1 |
| KURTEN, H | 1 |
| BURSELL, S | 1 |
| NAESLUND, G | 1 |
| NAESLUND, J | 1 |
| SWENSON, KE | 1 |
| KUTSCHER, W | 1 |
| SCHIPPERS, M | 1 |
| HORCHLER, A | 2 |
| ZILLICH, H | 1 |
| LUHRS, W | 2 |
| BOTHE, H | 1 |
| TSIELENS, EA | 1 |
| SKARDE, IK | 1 |
| NARURKAR, MV | 1 |
| KUMTA, US | 1 |
| SAHASRABUDHE, MB | 1 |
| SCHNEIDER, WC | 1 |
| ROTHERHAM, J | 1 |
| FOCHEM, K | 1 |
| SPURNY, J | 1 |
| MARUYAMA, M | 1 |
| UCHIDA, M | 1 |
| Wyss, MT | 1 |
| Weber, B | 1 |
| Honer, M | 1 |
| Späth, N | 1 |
| Ametamey, SM | 1 |
| Westera, G | 1 |
| Bode, B | 1 |
| Kaim, AH | 1 |
| Buck, A | 1 |
| GANSSLEN, M | 1 |
| BUCKLEY, JJ | 1 |
| BUCKLEY, SM | 1 |
| SNIPES, AE | 1 |
| WOODWARD, GE | 1 |
| DEGLI ESPOSTI, A | 1 |
| Aoyama, C | 1 |
| Liao, H | 1 |
| Ishidate, K | 1 |
| LINDEMAYR, W | 1 |
| COOK, JW | 1 |
| SCHOENTAL, R | 1 |
| Yoshimoto, M | 1 |
| Waki, A | 1 |
| Obata, A | 1 |
| Furukawa, T | 1 |
| Yonekura, Y | 1 |
| Fujibayashi, Y | 1 |
| Gillies, RJ | 1 |
| Morse, DL | 1 |
| Mason, JB | 1 |
| Choi, SW | 1 |
| Leung, HW | 1 |
| Kamendulis, LM | 1 |
| Stott, WT | 1 |
| Likavcanová, K | 1 |
| Dobrota, D | 1 |
| Liptaj, T | 1 |
| Prónayová, N | 1 |
| Mlynárik, V | 1 |
| Belan, V | 1 |
| Galanda, M | 1 |
| Béres, A | 1 |
| De Riggo, J | 1 |
| Rubello, D | 2 |
| Al-Nahhas, A | 1 |
| Serkova, NJ | 1 |
| Márián, T | 1 |
| Szabó-Péli, J | 1 |
| Németh, E | 1 |
| Trón, L | 1 |
| Friedlander, E | 1 |
| Szabó, A | 1 |
| Balkay, L | 1 |
| Veress, G | 1 |
| Krasznai, Z | 1 |
| Kubota, K | 1 |
| Furumoto, S | 1 |
| Iwata, R | 1 |
| Fukuda, H | 1 |
| Kawamura, K | 1 |
| Ishiwata, K | 1 |
| Piel, M | 1 |
| Bauman, A | 1 |
| Baum, RP | 1 |
| Höhnemann, S | 1 |
| Klette, I | 1 |
| Wortmann, R | 1 |
| Rösch, F | 1 |
| Groves, AM | 1 |
| Win, T | 1 |
| Haim, SB | 1 |
| Ell, PJ | 1 |
| Kwee, SA | 1 |
| DeGrado, TR | 1 |
| Talbot, JN | 1 |
| Gutman, F | 1 |
| Coel, MN | 1 |
| VIOLLIER, G | 1 |
| Steffen-Smith, EA | 1 |
| Wolters, PL | 1 |
| Albert, PS | 1 |
| Baker, EH | 1 |
| Shimoda, KC | 1 |
| Barnett, AS | 1 |
| Warren, KE | 1 |
| Mintz, A | 1 |
| Wang, L | 1 |
| Ponde, DE | 1 |
| Dingli, D | 1 |
| Lowe, VJ | 1 |
| Canty, DJ | 1 |
| Blusztajn, JK | 1 |
| Bhakoo, KK | 1 |
| Williams, SR | 1 |
| Florian, CL | 1 |
| Land, H | 1 |
| Noble, MD | 1 |
| Henning, SM | 1 |
| Swendseid, ME | 1 |
| Albright, CD | 1 |
| Liu, R | 1 |
| Mar, MH | 1 |
| Shin, OH | 1 |
| Vrablic, AS | 1 |
| Salganik, RI | 1 |
| Glade, MJ | 1 |
| Hara, T | 2 |
| Yuasa, M | 1 |
| Snyder, F | 1 |
| Snyder, C | 1 |
| Mirowski, M | 1 |
| Hanausek, M | 1 |
| Sherman, U | 1 |
| Adams, AK | 1 |
| Walaszek, Z | 1 |
| Slaga, TJ | 1 |
| Locker, J | 1 |
| Newberne, PM | 1 |
| Rogers, AE | 1 |
| Warmsley, AM | 1 |
| Phillips, B | 1 |
| Pasternak, CA | 1 |
| Cookson, JC | 1 |
| Paton, WD | 1 |
| Werth, G | 1 |
| Berninger, H | 1 |
| Schnabel, KH | 1 |
| Stöger, R | 1 |
| Menkès, G | 1 |
| Weiss, H | 1 |
| Meyer, M | 1 |
| Bensow, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Liquid Biopsy Evaluation and Repository Development at Princess Margaret[NCT03702309] | 2,500 participants (Anticipated) | Observational | 2017-08-03 | Recruiting | |||
| Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206] | 12 participants (Anticipated) | Observational | 2020-12-31 | Not yet recruiting | |||
| Peptide Receptor Radionuclide Therapy (PRRT) in Tumors With High Expression of Somatostatin Receptors[NCT04790708] | 250 participants (Anticipated) | Interventional | 2018-07-02 | Recruiting | |||
| Cancer Localization in the Prostate With F-18 Fluorocholine Positron Emission Tomography[NCT01310192] | Phase 1 | 20 participants (Actual) | Interventional | 2004-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
52 reviews available for choline and Neoplasms
| Article | Year |
|---|---|
Association between Levels of Trimethylamine N-Oxide and Cancer: A Systematic Review and Meta-Analysis.
Topics: Betaine; Choline; Female; Humans; Neoplasms; Risk Factors | 2023 |
Microbiota Effect on Trimethylamine N-Oxide Production: From Cancer to Fitness-A Practical Preventing Recommendation and Therapies.
Topics: Animals; Cardiovascular Diseases; Choline; Inflammation; Methylamines; Microbiota; Neoplasms | 2023 |
Phospholipase D and Choline Metabolism.
Topics: Animals; Choline; Humans; Hydrolysis; Neoplasms; Phosphatidic Acids; Phospholipase D; Signal Transdu | 2020 |
A novel roadmap connecting the
Topics: Choline; Humans; Magnetic Resonance Spectroscopy; Neoplasms; Proton Magnetic Resonance Spectroscopy; | 2021 |
How to use PET/CT in the evaluation of response to radiotherapy.
Topics: Choline; Fluorodeoxyglucose F18; Humans; Magnetic Resonance Imaging; Multimodal Imaging; Neoplasms; | 2018 |
Association of choline and betaine levels with cancer incidence and survival: A meta-analysis.
Topics: Betaine; Choline; Diet; Humans; Incidence; Neoplasms; Survival Analysis | 2019 |
Choline transport for phospholipid synthesis: An emerging role of choline transporter-like protein 1.
Topics: Animals; Antigens, CD; Biological Transport; Cell Membrane; Choline; Choline Deficiency; Humans; Liv | 2019 |
Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer.
Topics: Animals; Choline; Glycerylphosphorylcholine; Humans; Metabolic Networks and Pathways; Neoplasms; Sub | 2019 |
Choline transporter-like proteins CTLs/SLC44 family as a novel molecular target for cancer therapy.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Apoptosis; Biological Transport; Choline; Humans; Memb | 2014 |
PET tracers in musculoskeletal disease beyond FDG.
Topics: Amino Acids; Bone Diseases; Bone Neoplasms; Carbon Radioisotopes; Choline; Dideoxynucleosides; Fluor | 2014 |
Standardization and quantification in PET/CT imaging: tracers beyond FDG.
Topics: Carbon Radioisotopes; Choline; Humans; Medical Oncology; Methionine; Neoplasms; Positron-Emission To | 2014 |
Fluorocholine PET/computed tomography: physiologic uptake, benign findings, and pitfalls.
Topics: Abdomen; Central Nervous System; Choline; Contraindications; Fluorine Radioisotopes; Humans; Neoplas | 2014 |
Applications of PET imaging with radiolabelled choline (11C/18F-choline).
Topics: Choline; Humans; Image Enhancement; Isotope Labeling; Neoplasms; Positron-Emission Tomography; Radio | 2015 |
Choline metabolism-based molecular diagnosis of cancer: an update.
Topics: Animals; Choline; Diagnostic Imaging; Humans; Metabolic Networks and Pathways; Molecular Diagnostic | 2015 |
Pitfalls and Artifacts in the Use of PET/CT in Oncology Imaging.
Topics: Artifacts; Choline; Contrast Media; Female; Fluorodeoxyglucose F18; Humans; Male; Metals; Motion; Mu | 2015 |
New Positron-Emission Tomography/Computed Tomography Imaging for Bone Metastases
.
Topics: Bone Neoplasms; Choline; Female; Fluorodeoxyglucose F18; Humans; Male; Neoplasm Metastasis; Neoplasm | 2016 |
Choline and betaine consumption lowers cancer risk: a meta-analysis of epidemiologic studies.
Topics: Animals; Betaine; Choline; Dietary Supplements; Humans; Incidence; Neoplasms; Risk | 2016 |
[Positron emission tomography and evaluation of response to targeted therapies].
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cell Hypoxia; Cell Proliferation; Choline; ErbB Recept | 2009 |
Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biomarkers; Choline; Drug Delivery Systems; | 2010 |
PET with (18)F-labelled choline-based tracers for tumour imaging: a review of the literature.
Topics: Brain Neoplasms; Choline; Humans; Liver Neoplasms; Male; Neoplasms; Positron-Emission Tomography; Pr | 2010 |
Metabolic positron emission tomography imaging in cancer detection and therapy response.
Topics: Choline; Drug Monitoring; Fluorodeoxyglucose F18; Humans; Molecular Imaging; Neoplasm Staging; Neopl | 2011 |
MR evaluation of response to targeted treatment in cancer cells.
Topics: Animals; Biomarkers, Tumor; Choline; Humans; Magnetic Resonance Imaging; Molecular Targeted Therapy; | 2011 |
Multimodality molecular imaging of apoptosis in oncology.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Caspases; Choline; Humans; Infrared Rays; Mole | 2011 |
MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer.
Topics: Animals; Choline; Glucose; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mole | 2011 |
Exploiting tumor metabolism for non-invasive imaging of the therapeutic activity of molecularly targeted anticancer agents.
Topics: Antineoplastic Agents; Biomarkers; Choline; Enzyme Activation; Enzyme Inhibitors; Glucose; Humans; M | 2011 |
Dietary choline deficiency causes DNA strand breaks and alters epigenetic marks on DNA and histones.
Topics: Animals; Choline; Choline Deficiency; DNA Breaks; DNA Damage; Epigenesis, Genetic; Genomic Instabili | 2012 |
Choline metabolism in malignant transformation.
Topics: Animals; Cell Transformation, Neoplastic; Choline; Humans; Magnetic Resonance Spectroscopy; Neoplasm | 2011 |
Application of metabolic PET imaging in radiation oncology.
Topics: Acetates; Carbon Radioisotopes; Carcinoma; Choline; Confounding Factors, Epidemiologic; Female; Fluo | 2012 |
The role of positron emission tomography using carbon-11 and fluorine-18 choline in tumors other than prostate cancer: a systematic review.
Topics: Carbon Radioisotopes; Choline; Fluorine Radioisotopes; Humans; Neoplasms; Positron-Emission Tomograp | 2012 |
New PET imaging agents in the management of solid cancers.
Topics: Apoptosis; Cell Hypoxia; Cell Membrane; Cell Proliferation; Choline; Dideoxynucleosides; Heterocycli | 2012 |
Structure and function of choline kinase isoforms in mammalian cells.
Topics: Amino Acid Sequence; Animals; Cell Division; Choline; Choline Kinase; Humans; Isomerism; Liver; Mamm | 2004 |
Oncological molecular imaging: nuclear medicine techniques.
Topics: Apoptosis; Cell Division; Choline; Gene Expression; Genetic Therapy; Glycolysis; Humans; Hypoxia; Ne | 2003 |
In vivo magnetic resonance spectroscopy in cancer.
Topics: Animals; Biopsy; Brain; Choline; Citric Acid; Esters; Female; Humans; Hydrogen; Isotopes; Lipids; Ma | 2005 |
Effects of alcohol on folate metabolism: implications for carcinogenesis.
Topics: Animals; Betaine; Biological Availability; Central Nervous System Depressants; Choline; Ethanol; Fol | 2005 |
Review of the carcinogenic activity of diethanolamine and evidence of choline deficiency as a plausible mode of action.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Choline; Choline Deficiency; Ethanolamines; Female; Hum | 2005 |
Therapeutic targets and biomarkers identified in cancer choline phospholipid metabolism.
Topics: Animals; Antineoplastic Agents; Biomarkers; Choline; Drug Delivery Systems; Drug Therapy; Humans; Ne | 2006 |
Choline metabolism in cancer: implications for diagnosis and therapy.
Topics: Animals; Choline; Gene Expression; Humans; Magnetic Resonance Imaging; Neoplasms; Phospholipids | 2006 |
Non-[18F]FDG PET in clinical oncology.
Topics: Antibodies; Choline; Dideoxynucleosides; Dihydroxyphenylalanine; Fluorodeoxyglucose F18; Medical Onc | 2007 |
(18)F-labeled positron emission tomographic radiopharmaceuticals in oncology: an overview of radiochemistry and mechanisms of tumor localization.
Topics: Amino Acids; Animals; Bone and Bones; Cell Hypoxia; Choline; Dideoxynucleosides; Dihydroxyphenylalan | 2007 |
Cancer imaging with fluorine-18-labeled choline derivatives.
Topics: Brain Neoplasms; Carcinoma, Hepatocellular; Choline; Esophageal Neoplasms; Female; Fluorine Radioiso | 2007 |
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
Topics: Adenosine; Animals; Azacitidine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cell Trans | 1984 |
Lecithin and choline in human health and disease.
Topics: Animals; Choline; Choline Deficiency; Humans; Neoplasms; Nutritional Requirements; Phosphatidylcholi | 1994 |
Choline and human nutrition.
Topics: Animals; Brain; Choline; Choline Deficiency; Humans; Neoplasms; Nutritional Physiological Phenomena; | 1994 |
Choline phospholipids: signal transduction and carcinogenesis.
Topics: Animals; Choline; Humans; Neoplasms; Phospholipids; Protein Kinase C; Signal Transduction | 1993 |
The role of folate, choline, and methionine in carcinogenesis induced by methyl-deficient diets.
Topics: Animals; Choline; Choline Deficiency; Diet; Folic Acid; Folic Acid Deficiency; Humans; Liver Neoplas | 1996 |
Choline. A nutrient that is involved in the regulation of cell proliferation, cell death, and cell transformation.
Topics: Animals; Cell Death; Cell Division; Cell Line; Cell Transformation, Neoplastic; Choline; Choline Def | 1996 |
Diet, apoptosis, and carcinogenesis.
Topics: Animals; Apoptosis; Choline; Choline Deficiency; Diet; Epidermal Growth Factor; Humans; Neoplasms; S | 1997 |
Glycerolipids and cancer.
Topics: Animals; Choline; Chromatography, Thin Layer; Dogs; Ethanolamines; Ethers; Glycerides; Glycerol; Hum | 1975 |
Choline: an important nutrient in brain development, liver function and carcinogenesis.
Topics: Alanine Transaminase; Animals; Brain; Choline; Diet; Humans; Liver; Neoplasms; Rats | 1992 |
Gene amplification during stages of carcinogenesis.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Choline; Cocarcinogenesis; Diet; Gene Ampli | 1991 |
Labile methyl groups and the promotion of cancer.
Topics: Animals; Antibody Formation; Carcinogens; Choline; Choline Deficiency; Diet; DNA; Folic Acid; Folic | 1986 |
Mechanisms of neuromuscular block. A review article.
Topics: Acetylcholine; Action Potentials; Animals; Cats; Cell Membrane; Choline; Humans; Membrane Potentials | 1969 |
3 trials available for choline and Neoplasms
| Article | Year |
|---|---|
Phase I study of copper-binding agent ATN-224 in patients with advanced solid tumors.
Topics: Adult; Aged; Ceruloplasmin; Chelating Agents; Chelation Therapy; Choline; Copper; Cytokines; Endothe | 2008 |
Early assessment of radiation response using a novel functional imaging modality -- [18F]fluorocholine PET (FCH-PET): a pilot study.
Topics: Aged; Aged, 80 and over; Choline; Female; Humans; Male; Middle Aged; Neoplasms; Pilot Projects; Posi | 2012 |
Detection and characterization of neurotoxicity in cancer patients using proton MR spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Child; Child, Preschool; Choline; Creatine; Female; Humans; Magnet | 2008 |
72 other studies available for choline and Neoplasms
| Article | Year |
|---|---|
Superiority of 11 C-Choline PET/CT in the Delineation of a Rare Intracranial Diffuse Embryonic Tumor.
Topics: Adult; Choline; Female; Fluorodeoxyglucose F18; Humans; Neoplasms; Positron Emission Tomography Comp | 2022 |
Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab.
Topics: Acetylcholine; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; B7-H1 Antige | 2022 |
Metabolic Labeling-Based Chemoproteomics Establishes Choline Metabolites as Protein Function Modulators.
Topics: Animals; Antineoplastic Agents; Choline; Humans; Mammals; Neoplasms; Phosphorylcholine; Proteome | 2022 |
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action.
Topics: Antineoplastic Agents; Cell Proliferation; Choline; Choline Kinase; Humans; Molecular Docking Simula | 2023 |
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action.
Topics: Antineoplastic Agents; Cell Proliferation; Choline; Choline Kinase; Humans; Molecular Docking Simula | 2023 |
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action.
Topics: Antineoplastic Agents; Cell Proliferation; Choline; Choline Kinase; Humans; Molecular Docking Simula | 2023 |
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action.
Topics: Antineoplastic Agents; Cell Proliferation; Choline; Choline Kinase; Humans; Molecular Docking Simula | 2023 |
Detection of brown tumors by [18F]F-choline PET/CT performed in a patient with secondary hyperparathyroidism.
Topics: Adult; Choline; Female; Humans; Hyperparathyroidism, Secondary; Neoplasms; Parathyroid Glands; Posit | 2023 |
Two-step tumor-targeting therapy via integrating metabolic lipid-engineering with in situ click chemistry.
Topics: Animals; Cell Line, Tumor; Choline; Click Chemistry; Coloring Agents; Drug Delivery Systems; Erythro | 2020 |
Biocompatible Ionic Liquid Enhances Transdermal Antigen Peptide Delivery and Preventive Vaccination Effect.
Topics: Administration, Cutaneous; Animals; Antigens, Neoplasm; Cancer Vaccines; Cell Line, Tumor; Choline; | 2020 |
Simulation of Deep Eutectic Solvents' Interaction with Membranes of Cancer Cells Using COSMO-RS.
Topics: Choline; Ethylene Glycol; Glycerol; Hydrogen Bonding; Neoplasms; Solvents | 2020 |
Targeting personalized medicine in a non-Hodgkin lymphoma patient with 18F-FDG and 18F-choline PET/CT.
Topics: Choline; Fluorodeoxyglucose F18; Humans; Lymph Nodes; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neop | 2017 |
N-Heterocyclic choline analogues based on 1,2,3,4-tetrahydro(iso)quinoline scaffold with anticancer and anti-infective dual action.
Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Cell Line, Tumor; Choline; Drug Delivery Syst | 2017 |
Total Methionine Restriction Treatment of Cancer.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Choline; Homocysteine; Humans; Liver; Methionine; Mic | 2019 |
Cancer metabolism and metabolomics.
Topics: Animals; Choline; Energy Metabolism; Humans; Lipid Metabolism; Magnetic Resonance Spectroscopy; Meta | 2019 |
Biodistribution and delivery efficiency of unmodified tumor-derived exosomes.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line; Chemistry, Pharmaceutical; C | 2015 |
Fluorescence Ratiometric Assay Strategy for Chemical Transmitter of Living Cells Using H2O2-Sensitive Conjugated Polymers.
Topics: Acetylcholine; Biosensing Techniques; Cell Line, Tumor; Choline; Fluorescence Resonance Energy Trans | 2015 |
A two-step strategy to radiolabel choline phospholipids with
Topics: Amines; Animals; Azides; Cell Line, Tumor; Cell Membrane; Choline; Click Chemistry; Cycloaddition Re | 2016 |
Molecular imaging and targeted therapies in oncology: new concepts in treatment response assessment. a collection of cases.
Topics: Aged; Antineoplastic Agents; Carbon Radioisotopes; Choline; Clinical Trials as Topic; Female; Fluoro | 2008 |
The influence of sodium thiosulfate on experimental tumor induction.
Topics: Adenoma; Animals; Choline; Choline Deficiency; Humans; Liver; Liver Neoplasms; Neoplasms; Neoplasms, | 1948 |
Choline PET for monitoring early tumor response to photodynamic therapy.
Topics: Algorithms; Animals; Cell Line, Tumor; Cell Survival; Choline; Humans; Image Processing, Computer-As | 2010 |
Non FDG PET.
Topics: Choline; Humans; Methionine; Neoplasm Staging; Neoplasms; Positron-Emission Tomography; Practice Gui | 2010 |
1H-14N HSQC detection of choline-containing compounds in solutions.
Topics: Algorithms; Animals; Choline; Dairy Products; Deuterium Oxide; Disease Progression; Magnetic Resonan | 2010 |
Vitamin content of mouse epidermis during methylcholanthrene carcinogenesis; biotin, choline, inositol, rho-aminobenzoic acid, and pyridoxine.
Topics: 4-Aminobenzoic Acid; Acids; Biotin; Carcinogenesis; Choline; Epidermis; Inositol; Methylcholanthrene | 1946 |
The occurrence of neoplasms in the liver, lungs, and other tissues of rats as a result of prolonged choline deficiency.
Topics: Animals; Choline; Choline Deficiency; Liver; Neoplasms; Rats | 1946 |
Proton Magnetic Resonance Spectroscopy in adult cancer patients with delirium.
Topics: Adult; Aged; Aspartic Acid; Bone Marrow Transplantation; Choline; Delirium; Female; Humans; Magnetic | 2011 |
Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography.
Topics: Animals; Carbon Radioisotopes; Cell Line, Tumor; Choline; Deuterium; Disease Models, Animal; Fluorod | 2012 |
Minimization of spectral pattern changes during HRMAS experiments at 37 degrees celsius by prior focused microwave irradiation.
Topics: Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Choline; Glioblastoma; Humans; Lipids; Magnetic R | 2012 |
Alterations in target cell membrane phospholipids alter T cell but not NK cell killing.
Topics: Animals; Cell Line; Cell Membrane; Choline; Cytotoxicity, Immunologic; Killer Cells, Natural; Mice; | 2013 |
Malignant transformation: the role of MRS.
Topics: Biomarkers, Tumor; Cell Transformation, Neoplastic; Choline; Diagnosis, Computer-Assisted; Glucose; | 2012 |
Choline-releasing glycerophosphodiesterase EDI3 links the tumor metabolome to signaling network activities.
Topics: Animals; Choline; Diglycerides; Humans; Lysophospholipids; Models, Biological; Neoplasms; Phosphatid | 2012 |
Optical molecular imaging approach for rapid assessment of response of individual cancer cells to chemotherapy.
Topics: 4-Chloro-7-nitrobenzofurazan; Analysis of Variance; Antineoplastic Agents; Apoptosis; Cell Survival; | 2012 |
[Esterification of fatty acids by alcohols and functional role of polar and non-polar lipids in blood flow. Double bonds of lipid fatty acids in lipoproteins].
Topics: Adolescent; Adult; Alcohols; Animals; Arteriosclerosis; Child; Cholesterol Esters; Choline; Fatty Ac | 2003 |
Comparison of polarization transfer sequences for enhancement of signals in clinical 31P MRS studies.
Topics: Chi-Square Distribution; Choline; Magnetic Resonance Spectroscopy; Models, Theoretical; Neoplasms; P | 2003 |
[Results with choline citrate therapy of inoperable cervical carcinoma].
Topics: Cervix Uteri; Choline; Female; Humans; Neoplasms; Uterine Cervical Neoplasms | 1952 |
[Common role of lactic acid and choline in the disturbed metabolism of the cancer patient and in medical inhibition of cancer growth].
Topics: Biochemical Phenomena; Choline; Humans; Lactates; Lactic Acid; Neoplasms | 1952 |
Investigations of malignant tumours with radioactive phosphocholine.
Topics: Choline; Humans; Neoplasms; Phosphorylcholine; Radioactivity | 1953 |
[Quantitative determination of choline in the blood in carcinoma with increased phosphatase activity].
Topics: Biochemical Phenomena; Carcinoma; Choline; Hematologic Diseases; Lymphatic Diseases; Neoplasms; Phos | 1954 |
[Alteration therapy of malignant neoplasms with neurohormones].
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Choline; Neoplasms; Neurotransmitter Agents | 1954 |
[Thoughts and suggestions on the cancer problem].
Topics: Choline; Diet; Humans; Neoplasms; Suggestion; Thinking | 1955 |
[Possibilities of influencing malignant tumors in animals by fluorcholine].
Topics: Animals; Choline; Fluorides; Fluorine; Humans; Neoplasms; Neoplasms, Experimental | 1956 |
[Level of free choline in blood serum in cancerous patients].
Topics: Choline; Hematologic Diseases; Humans; Lymphatic Diseases; Neoplasms; Serum | 1956 |
On the susceptibility of malignant animal tumours by fluorocholine.
Topics: Animals; Antineoplastic Agents; Choline; Humans; Neoplasms | 1957 |
Choline-oxidase activity of host-livers of tumour-bearing animals.
Topics: Animals; Choline; Liver; Neoplasms; Oxidation-Reduction; Oxidoreductases | 1957 |
Phosphorus compounds in animal tissues. VI. Deoxycytidine diphosphate choline and deoxycytidine diphosphate ethanolamine in the Novikoff hepatoma.
Topics: Animals; Choline; Deoxycytosine Nucleotides; Encephalomyelitis; Ethanolamine; Ethanolamines; Liver N | 1958 |
[The effect of cholin citrate on the leukocyte count during radiotherapy with carcinoma dosage].
Topics: Choline; Citrates; Citric Acid; Genitalia; Genitalia, Female; Leukocyte Count; Neoplasms | 1954 |
Studies on the mode of action of RC4, a new anti-cancer agent containing ethyleneimino ring. I. Effects of RC4 and allied agents on glycolysis, respiration, hexokinase and phosphatase of Ehrlich ascites tumor cells and on choline-esterase of human blood.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Choline; Cholinesterases; Esterases; Glyco | 1960 |
18F-choline in experimental soft tissue infection assessed with autoradiography and high-resolution PET.
Topics: Animals; Autoradiography; Choline; Fluorodeoxyglucose F18; Metabolic Clearance Rate; Muscle, Skeleta | 2004 |
[Advances in the treatment of tumors, leukemia and granuloma].
Topics: Anura; Choline; Granuloma; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Neoplas | 1950 |
The effect of choline deficiency on the development of tumors produced by butter yellow.
Topics: Choline; Choline Deficiency; Humans; Liver Neoplasms; Neoplasms; p-Dimethylaminoazobenzene | 1951 |
Choline oxidase activity in rat liver during 3'-methyl-4-dimethylaminoazobenzene carcinogenesis.
Topics: Alcohol Oxidoreductases; Animals; Carcinogenesis; Choline; Liver; Methyldimethylaminoazobenzene; Neo | 1951 |
[Antibiotic therapy].
Topics: Anemia; Anemia, Hemolytic; Anti-Bacterial Agents; Choline; Neoplasms | 1952 |
[Effects of choline in hyperfunctioning thyroid adenoma in a child].
Topics: Child; Choline; Cortisone; Goiter, Nodular; Humans; Hyperthyroidism; Neoplasms; Receptors, Thyrotrop | 1952 |
[Cutaneous lymphocytoma].
Topics: Choline; Humans; Neoplasms; Pseudolymphoma; Skin | 1949 |
Effect of choline on experimental carcinogenesis.
Topics: Animals; Carcinogenesis; Choline; Humans; Neoplasms | 1949 |
Radiolabeled choline as a proliferation marker: comparison with radiolabeled acetate.
Topics: Acetates; Animals; Biomarkers, Tumor; Carbon Radioisotopes; Cell Line, Tumor; Cell Proliferation; Ch | 2004 |
In vitro study of astrocytic tumour metabolism by proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Astrocytes; Astrocytoma; Brain; Brain Neoplasms; Choline; Chromium; Creatine; Gliobla | 2005 |
Clinical PET in oncology: not only FDG.
Topics: Acetates; Carbon Radioisotopes; Choline; Fluorodeoxyglucose F18; Gallium Radioisotopes; Humans; Medi | 2006 |
Na+/Ca2+ exchanger inhibitors modify the accumulation of tumor-diagnostic PET tracers in cancer cells.
Topics: Bepridil; Calcium; Carbon Radioisotopes; Cell Line, Tumor; Choline; Flow Cytometry; Fluorodeoxygluco | 2007 |
Comparison of 18F-fluoromethylcholine and 2-deoxy-D-glucose in the distribution of tumor and inflammation.
Topics: Animals; Autoradiography; Brain; Choline; Deoxyglucose; Fluorine Radioisotopes; Inflammation; Lung; | 2006 |
Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging.
Topics: Choline; Chromatography, High Pressure Liquid; Fluorine Radioisotopes; Molecular Structure; Neoplasm | 2007 |
Could choline PET play a role in malignancies other than prostate cancer?
Topics: Carbon Radioisotopes; Choline; Humans; Male; Neoplasms; Positron-Emission Tomography; Prostatic Neop | 2008 |
Influence of dietary fat on the development of tumors in choline-deficient rats.
Topics: Animals; Choline; Diet; Fats; Neoplasms; Neoplasms, Experimental | 1949 |
Comparison of radiolabeled choline and ethanolamine as probe for cancer detection.
Topics: Carbon Radioisotopes; Cell Line, Tumor; Choline; Ethanolamine; Ethanolamines; Fibroblasts; Fluorine | 2008 |
Plasma membrane phospholipid labeling to estimate tumor burden and kinetics.
Topics: Animals; Carbon Radioisotopes; Cell Line, Tumor; Cell Membrane; Choline; Ethanolamine; Fibroblasts; | 2008 |
Immortalization and transformation are associated with specific alterations in choline metabolism.
Topics: Animals; Antigens, Viral, Tumor; Cell Division; Cell Line, Transformed; Choline; Glioblastoma; Human | 1996 |
Workshop on Folate, B12, and Choline. Sponsored by the Panel on Folate and other B vitamins of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine, Washington, D.C., March 3-4,
Topics: Biological Availability; Biomarkers; Cardiovascular Diseases; Choline; Congenital Abnormalities; Fem | 1999 |
Automated synthesis of [11C]choline, a positron-emitting tracer for tumor imaging.
Topics: Carbon Radioisotopes; Choline; Humans; Neoplasms; Radiopharmaceuticals; Technology, Radiologic; Tomo | 1999 |
18F-fluorocholine: a new oncologic PET tracer.
Topics: Choline; Fluorine Radioisotopes; Humans; Neoplasms; Quaternary Ammonium Compounds; Radiopharmaceutic | 2001 |
An enzyme-linked immunosorbent assay for p65 oncofetal protein and its potential as a new marker for cancer risk assessment in rodents and humans.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Choline; Choline Deficiency; Diethylni | 1992 |
The use of zonal centrifugation to study membrane formation during the life cycle of mammalian cells. Synthesis of 'marker' enzymes and other components of cellular organelles.
Topics: Cell Division; Cell Nucleus; Centrifugation, Zonal; Choline; Culture Techniques; Electron Transport | 1970 |
[Chemistry of malignolipin].
Topics: Amino Alcohols; Animals; Carcinoma; Chemical Phenomena; Chemistry; Choline; Chromatography, Paper; C | 1972 |
[Directed internal cancer therapy. Combined hyperergization therapy].
Topics: Acetazolamide; Calcium; Choline; Female; Humans; Male; Middle Aged; Neoplasms; Thyroid Hormones | 1967 |
[The "reequilibration" test and its use in the treatment of certain forms of cancer and other afflictions].
Topics: Adenosine Triphosphate; Asparagine; Betaine; Choline; Creatine; Cysteine; Deficiency Diseases; Elect | 1966 |
[Studies on the in vitro hydrolysis of succinyldicholine and benzoylcholine in blood donors and carcinomatous patients].
Topics: Benzoates; Blood Donors; Choline; Cholinesterases; Female; Humans; In Vitro Techniques; Male; Neopla | 1966 |