Page last updated: 2024-10-16

choline and Necrosis

choline has been researched along with Necrosis in 59 studies

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"This meta-analysis indicated 11C-choline has high diagnostic accuracy for the identification of tumor relapse from radiation induced necrosis in gliomas."8.98Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis. ( Chen, G; Gao, L; Li, T; Xu, W; Zheng, J, 2018)
"The aim of this study is to assess the different metabolic activities characteristic of glioma recurrence and radiation necrosis (RN) and to explore the diagnostic accuracy for differentiation of the two conditions using (11)C-methionine (MET), (11)C-choline (CHO), and (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)."7.80Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis. ( Asano, Y; Iwama, T; Miwa, K; Nomura, Y; Shinoda, J; Takenaka, S; Yano, H; Yonezawa, S, 2014)
"Weanling rats fed a choline-deficient diet develop kidney oxidative damage, tubular and cortical kidney necrosis, renal failure and animal death."7.79The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency. ( Boveris, A; Monserrat, AJ; Ossani, GP; Repetto, MG, 2013)
"To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy."7.77Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy. ( Chen, L; Guan, Y; Lin, X; Tan, H, 2011)
"The influence of several factors on the development of acute hemorrhagic pancreatitis (pancreatic necrosis) with fat necrosis in mice fed DL-ethionine with a choline-deficient diet has been investigated."7.65Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. ( Lombardi, B; Rao, NK, 1975)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."5.29Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"This meta-analysis indicated 11C-choline has high diagnostic accuracy for the identification of tumor relapse from radiation induced necrosis in gliomas."4.98Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis. ( Chen, G; Gao, L; Li, T; Xu, W; Zheng, J, 2018)
" This biochemical information can be processed and presented as density maps of several metabolites, among them N-acetylaspartate (marker of neuronal viability), choline (marker of membrane turnover), creatine (related to the energy state of the cells), myo-Inositol (exclusively found in astrocytes), lipids and lactate (observed in necrosis and other pathological processes) which mean relevant information in the context of brain tumors."4.85Proton magnetic resonance spectroscopy imaging in the study of human brain cancer. ( Celda, B; Martínez-Bisbal, MC, 2009)
"The aim of this study is to assess the different metabolic activities characteristic of glioma recurrence and radiation necrosis (RN) and to explore the diagnostic accuracy for differentiation of the two conditions using (11)C-methionine (MET), (11)C-choline (CHO), and (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)."3.80Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis. ( Asano, Y; Iwama, T; Miwa, K; Nomura, Y; Shinoda, J; Takenaka, S; Yano, H; Yonezawa, S, 2014)
"Weanling rats fed a choline-deficient diet develop kidney oxidative damage, tubular and cortical kidney necrosis, renal failure and animal death."3.79The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency. ( Boveris, A; Monserrat, AJ; Ossani, GP; Repetto, MG, 2013)
"To compare metabolic magnetic resonance (MR) imaging findings (ie, quantification of tumor choline concentration) with percentage of necrosis on pathologic examination in rabbits bearing VX2 liver tumors."3.77Quantitative proton MR spectroscopy as a biomarker of tumor necrosis in the rabbit VX2 liver tumor. ( Buijs, M; Geschwind, JF; Kamel, IR; Lee, KH; Liapi, E; Pan, L; Salibi, N; Ventura, VP; Vossen, JA, 2011)
"To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy."3.77Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy. ( Chen, L; Guan, Y; Lin, X; Tan, H, 2011)
"The influence of several factors on the development of acute hemorrhagic pancreatitis (pancreatic necrosis) with fat necrosis in mice fed DL-ethionine with a choline-deficient diet has been investigated."3.65Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. ( Lombardi, B; Rao, NK, 1975)
"A new experimental model has been found whereby acute hemorrhagic pancreatic necrosis with fat necrosis is induced in 100% of young female mice fed a choline-deficient diet supplemented with 0."3.65Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum. ( Lombardi, B; Rao, KN; Tuma, J, 1976)
"Postradiation treatment necrosis is one of the most serious late sequelae and appears within 6 months."3.01Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis. ( Aseel, A; McCarthy, P; Mohammed, A, 2023)
"necrosis in patients with primary brain tumors or brain metastasis."2.53Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis. ( Chen, YC; Chuang, MT; Liu, YS; Tsai, YS; Wang, CK, 2016)
"The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)."1.37[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011)
"Choline (Cho) was increased in 3 (11%), normal in 4 (14%), and reduced in 21 (75%) spectra."1.30Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings. ( Aw, YS; Chong, VF; Chua, EJ; Fan, YF; Ho, GL; Rumpel, H, 1999)
"Necrosis was present histologically in four of the five meningiomas classified either as atypical or papillary."1.30Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy. ( Handa, J; Inubushi, T; Matsuda, M; Morikawa, S; Nakasu, S; Shino, A, 1999)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."1.29Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"The necrosis was most pronounced in the predominantly oxidative-rich fiber-composed diaphragm."1.28Variable involvement of rat skeletal muscles in paraoxon-induced necrotizing myopathy. ( De Bleecker, JL; De Reuck, JL; van den Abeele, KG, 1992)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199014 (23.73)18.7374
1990's11 (18.64)18.2507
2000's11 (18.64)29.6817
2010's19 (32.20)24.3611
2020's4 (6.78)2.80

Authors

AuthorsStudies
Feng, A1
Yuan, P1
Huang, T1
Li, L1
Lyu, J1
Aseel, A1
McCarthy, P1
Mohammed, A1
Fuentes-Baile, M1
Bello-Gil, D1
Pérez-Valenciano, E1
Sanz, JM1
García-Morales, P1
Maestro, B1
Ventero, MP1
Alenda, C1
Barberá, VM1
Saceda, M1
Wang, AP1
Suryavanshi, T1
Marcucci, M1
Fong, C1
Whitton, AC1
Reddy, KKV1
Gao, L1
Xu, W2
Li, T1
Zheng, J1
Chen, G1
Fedele, TA1
Galdos-Riveros, AC1
Jose de Farias e Melo, H1
Magalhães, A1
Maria, DA1
Takeuchi, M1
Matsuzaki, K1
Harada, M1
Denninghoff, V1
Ossani, G1
Uceda, A1
Rugnone, M1
Fernández, E1
Fresno, C1
González, G1
Díaz, ML1
Avagnina, A1
Elsner, B1
Monserrat, A1
Hemminki, O1
Immonen, R1
Närväinen, J1
Kipar, A1
Paasonen, J1
Jokivarsi, KT1
Yli-Ollila, H1
Soininen, P1
Partanen, K1
Joensuu, T1
Parvianen, S1
Pesonen, SK1
Koski, A1
Vähä-Koskela, M1
Cerullo, V1
Pesonen, S1
Gröhn, OH1
Hemminki, A1
Takenaka, S1
Asano, Y1
Shinoda, J1
Nomura, Y1
Yonezawa, S1
Miwa, K1
Yano, H1
Iwama, T1
Bolcaen, J2
Descamps, B2
Deblaere, K2
Boterberg, T2
De Vos Pharm, F1
Kalala, JP2
Van den Broecke, C2
Decrock, E1
Leybaert, L1
Vanhove, C2
Goethals, I2
Chuang, MT1
Liu, YS1
Tsai, YS1
Chen, YC1
Wang, CK1
Gautheron, J1
Vucur, M1
Schneider, AT1
Severi, I1
Roderburg, C1
Roy, S1
Bartneck, M1
Schrammen, P1
Diaz, MB1
Ehling, J1
Gremse, F1
Heymann, F1
Koppe, C1
Lammers, T1
Kiessling, F1
Van Best, N1
Pabst, O1
Courtois, G1
Linkermann, A1
Krautwald, S1
Neumann, UP1
Tacke, F1
Trautwein, C1
Green, DR1
Longerich, T1
Frey, N1
Luedde, M1
Bluher, M1
Herzig, S1
Heikenwalder, M1
Luedde, T1
Lybaert, K1
Moerman, L1
De Vos, F1
Ben-Arie, G1
Serlin, Y1
Ivens, S1
Benifla, M1
Cagnano, E1
Melamed, I1
Merkin, V1
Shelef, I1
McLean, AS1
Huang, SJ1
Salter, M1
Nakajima, T1
Kumabe, T1
Kanamori, M1
Saito, R2
Tashiro, M1
Watanabe, M1
Tominaga, T1
Martínez-Bisbal, MC1
Celda, B1
Matoba, M1
Kondou, T1
Tanaka, T2
Kitadate, M1
Oota, K1
Tonami, H1
Isobe, T1
Akutsu, H1
Yamamoto, T1
Shiigai, M1
Masumoto, T1
Nakai, K1
Takano, S1
Anno, I1
Matsumura, A1
Buijs, M1
Vossen, JA1
Geschwind, JF1
Salibi, N1
Pan, L1
Ventura, VP1
Liapi, E1
Lee, KH1
Kamel, IR1
Tan, H1
Chen, L1
Guan, Y1
Lin, X1
Benitez, D1
Pezaroglo, H1
Martínez, V1
Casanova, G1
Cabrera, G1
Galanti, N1
González, M1
Cerecetto, H1
Lu, L1
Ni, J1
Zhou, T1
Fenech, M1
Wang, X1
Gaze, DC1
Ossani, GP1
Repetto, MG1
Boveris, A1
Monserrat, AJ1
Rock, JP1
Hearshen, D1
Scarpace, L1
Croteau, D1
Gutierrez, J1
Fisher, JL1
Rosenblum, ML1
Mikkelsen, T1
KLATSKIN, G1
KREHL, WA1
BAXTER, JH1
GOODMAN, H1
Herynek, V1
Burian, M1
Jirák, D1
Liscák, R1
Námestková, K1
Hájek, M1
Syková, E1
Sarri, E1
Garcia-Dorado, D1
Abellan, A1
Soler-Soler, J1
Giambarresi, LI1
Katyal, SL1
Lombardi, B4
Sijens, PE1
van Dijk, P1
Oudkerk, M1
Thielemann, LE1
Rodrigo, RA1
Oberhauser, EW1
Rosenblut, G1
Videla, LA1
Tracey, I1
Dunn, JF1
Parkes, HG1
Radda, GK1
Wald, LL1
Nelson, SJ1
Day, MR1
Noworolski, SE1
Henry, RG1
Huhn, SL1
Chang, S1
Prados, MD1
Sneed, PK1
Larson, DA1
Wara, WM1
McDermott, M1
Dillon, WP1
Gutin, PH1
Vigneron, DB1
Kinoshita, K1
Tada, E1
Matsumoto, K1
Asari, S1
Ohmoto, T1
Itoh, T1
Chong, VF1
Rumpel, H1
Aw, YS1
Ho, GL1
Fan, YF1
Chua, EJ1
Shino, A1
Nakasu, S1
Matsuda, M1
Handa, J1
Morikawa, S1
Inubushi, T1
Gasull, T1
DeGregorio-Rocasolano, N1
Zapata, A1
Trullas, R1
Harms, C2
Lautenschlager, M2
Bergk, A2
Freyer, D2
Weih, M1
Dirnagl, U2
Weber, JR2
Hörtnagl, H2
Cheng, LL1
Anthony, DC1
Comite, AR1
Black, PM1
Tzika, AA1
Gonzalez, RG1
Katchanov, J1
Kapinya, K1
Herwig, U1
Megow, D1
Kimura, T1
Sako, K1
Gotoh, T1
Tanaka, K1
Pani, P2
Columbano, A1
Dessi, S1
Porcu, M1
Ledda, GM1
Diaz, G1
Rao, NK1
Rao, KN3
Tuma, J1
Bernsen, HJ1
Heerschap, A1
van der Kogel, AJ1
van Vaals, JJ1
Prick, MJ1
Poels, EF1
Meyer, J1
Grotenhuis, JA1
Tessitore, L1
Dianzani, MU1
De Bleecker, JL1
van den Abeele, KG1
De Reuck, JL1
Palomba, L1
Coto, V1
Oliviero, U1
Lucariello, A1
Cerini, R1
Cocozza, M1
Cacciatore, L1
Porfido, FA1
Lingetti, M1
Scarpellino, F1
Talarico, M1
Virji, MA1
Stwertka, SA1
Olson, GL1
Takeuchi, J1
Takada, A1
Kanayama, R1
Ohara, N1
Okumura, Y1
Thomas, HM1
Williams, WL1
Clower, BR1
Reid, IM1
Barnes, RH1
Pond, WG1
Krook, L1
Zaki, FG1
Hoffbauer, FW1
Grande, F1
Zaki, GF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206]12 participants (Anticipated)Observational2020-12-31Not yet recruiting
Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.[NCT03009318]100 participants (Actual)Interventional2012-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for choline and Necrosis

ArticleYear
Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2023, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr

2023
Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis.
    Medicine, 2018, Volume: 97, Issue:29

    Topics: Carbon Radioisotopes; Choline; Diagnosis, Differential; Glioma; Humans; Necrosis; Neoplasm Recurrenc

2018
Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Hum

2016
Bench-to-bedside review: the value of cardiac biomarkers in the intensive care patient.
    Critical care (London, England), 2008, Volume: 12, Issue:3

    Topics: Biomarkers; CA-125 Antigen; Cardiovascular Diseases; CD40 Ligand; Choline; Creatine Kinase, MB Form;

2008
Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
    The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 2009, Volume: 53, Issue:6

    Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Glioblastoma; Humans; In

2009
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
    Journal of neuro-oncology, 1992, Volume: 13, Issue:2

    Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates;

1992

Other Studies

53 other studies available for choline and Necrosis

ArticleYear
Distinguishing Tumor Recurrence From Radiation Necrosis in Treated Glioblastoma Using Multiparametric MRI.
    Academic radiology, 2022, Volume: 29, Issue:9

    Topics: Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging;

2022
CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, induces Cell Death in Human Cancer Cells.
    Biomolecules, 2020, 02-03, Volume: 10, Issue:2

    Topics: 3T3-L1 Cells; Adenocarcinoma; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival;

2020
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:3

    Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err

2020
Prognostic relationship of metabolic profile obtained of melanoma B16F10.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2013, Volume: 67, Issue:2

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation;

2013
Preliminary observations and clinical value of lipid peak in high-grade uterine sarcomas using in vivo proton MR spectroscopy.
    European radiology, 2013, Volume: 23, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Choline; Female; Humans; Leiomyoma; Lipids; Magnetic Resonance Spect

2013
Molecular pathology of acute kidney injury in a choline-deficient model and fish oil protective effect.
    European journal of nutrition, 2014, Volume: 53, Issue:3

    Topics: Acute Kidney Injury; Animals; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Fish Oil

2014
In vivo magnetic resonance imaging and spectroscopy identifies oncolytic adenovirus responders.
    International journal of cancer, 2014, Jun-15, Volume: 134, Issue:12

    Topics: Adenoviridae; Animals; Biomarkers, Tumor; Carcinoma; Cells, Cultured; Choline; Cricetinae; Fatty Aci

2014
Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis.
    Neurologia medico-chirurgica, 2014, Volume: 54, Issue:4

    Topics: Adult; Aged; Area Under Curve; Brain; Brain Neoplasms; Carbon Isotopes; Choline; Combined Modality T

2014
(18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Choline; Diagnosis, Differential; Female; Fluorodeoxyglu

2015
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
    Nature communications, 2016, 06-21, Volume: 7

    Topics: Adipocytes; Adipose Tissue, White; Animals; Apoptosis; Body Mass Index; Caspase 8; Choline; Choline

2016
Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination between High-Grade Glioma and Radiation Necrosis in Rats.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Animals; Brain; Cell Line, Tumor; Choline; Diagnosis, Differential; Disease Models, Animal; Female;

2016
Diagnosing necrotic meningioma: a distinctive imaging pattern in diffusion MRI and MR spectroscopy.
    The neuroradiology journal, 2017, Volume: 30, Issue:1

    Topics: Choline; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Gluta

2017
Differential diagnosis between radiation necrosis and glioma progression using sequential proton magnetic resonance spectroscopy and methionine positron emission tomography.
    Neurologia medico-chirurgica, 2009, Volume: 49, Issue:9

    Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Neoplasms; Carbon Radioisotopes; Choline; Diagnosi

2009
Noninvasive monitoring of radiation-induced early therapeutic response using high-resolution MR imaging and proton MR spectroscopy in VX2 carcinoma.
    Journal of radiation research, 2010, Volume: 51, Issue:6

    Topics: Animals; Choline; Creatine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy

2010
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
    No shinkei geka. Neurological surgery, 2011, Volume: 39, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F

2011
Quantitative proton MR spectroscopy as a biomarker of tumor necrosis in the rabbit VX2 liver tumor.
    Journal of vascular and interventional radiology : JVIR, 2011, Volume: 22, Issue:8

    Topics: Animals; Choline; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Necrosis; Rabbits;

2011
Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy.
    Clinical nuclear medicine, 2011, Volume: 36, Issue:11

    Topics: Adult; Aged; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Female; Fluorodeoxyglucose F1

2011
Study of Trypanosoma cruzi epimastigote cell death by NMR-visible mobile lipid analysis.
    Parasitology, 2012, Volume: 139, Issue:4

    Topics: Animals; Apoptosis; Autophagy; Cell Death; Choline; Hydrogen Peroxide; Lipids; Magnetic Resonance Sp

2012
Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro.
    Nutrition and cancer, 2012, Volume: 64, Issue:3

    Topics: Adult; Apoptosis; Cell Death; Cell Nucleus; Cells, Cultured; Choline; Choline Deficiency; DNA Damage

2012
Novel biomarkers of cardiac ischemia: where are we at?
    Biomarkers in medicine, 2012, Volume: 6, Issue:5

    Topics: Albumins; Biomarkers; Choline; Fatty Acids, Nonesterified; Humans; Myocardial Ischemia; Necrosis; Tr

2012
The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency.
    Food & function, 2013, Feb-26, Volume: 4, Issue:3

    Topics: Acute Disease; Animals; Choline; Choline Deficiency; Corn Oil; Creatinine; Diet; Dietary Supplements

2013
Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis.
    Neurosurgery, 2002, Volume: 51, Issue:4

    Topics: Adult; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glioma; Humans; Lactic Acid; Lip

2002
The effect of alcohol on the choline requirement. II. Incidence of renal necrosis in weanling rats following short term ingestion of alcohol.
    The Journal of experimental medicine, 1954, Dec-01, Volume: 100, Issue:6

    Topics: Animals; Choline; Diet; Ethanol; Incidence; Kidney Diseases; Necrosis; Rats

1954
Renal and hepatic lipid alterations in choline deficiency: relationship to renal necrosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 89, Issue:4

    Topics: Choline; Choline Deficiency; Kidney; Kidney Diseases; Lipid Metabolism; Lipids; Necrosis

1955
Metabolite and diffusion changes in the rat brain after Leksell Gamma Knife irradiation.
    Magnetic resonance in medicine, 2004, Volume: 52, Issue:2

    Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Hippocampus; Lactic Acid; Magnetic

2004
Effects of hypoxia, glucose deprivation and acidosis on phosphatidylcholine synthesis in HL-1 cardiomyocytes. CTP:phosphocholine cytidylyltransferase activity correlates with sarcolemmal disruption.
    The Biochemical journal, 2006, Feb-15, Volume: 394, Issue:Pt 1

    Topics: Acidosis; Cell Hypoxia; Cell Line; Choline; Choline-Phosphate Cytidylyltransferase; Glucose; Hydroge

2006
Promotion of liver carcinogenesis in the rat by a choline-devoid diet: role of liver cell necrosis and regeneration.
    British journal of cancer, 1982, Volume: 46, Issue:5

    Topics: Animals; Choline; Diet; DNA; Liver; Liver Neoplasms; Liver Regeneration; Male; Necrosis; Neoplasms,

1982
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:5

    Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin

1994
N-acetyl-L-cysteine abolishes the bromoethylamine-induced choline incorporation into renal papillary tissue.
    Journal of biochemical toxicology, 1995, Volume: 10, Issue:5

    Topics: Acetylcysteine; Animals; Choline; Ethylamines; Female; Free Radical Scavengers; Kidney Medulla; Lyso

1995
An in vivo and in vitro H-magnetic resonance spectroscopy study of mdx mouse brain: abnormal development or neural necrosis?
    Journal of the neurological sciences, 1996, Sep-15, Volume: 141, Issue:1-2

    Topics: Animals; Aspartic Acid; Astrocytes; Brain; Brain Chemistry; Choline; Creatine; Dystrophin; Female; G

1996
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
    Journal of neurosurgery, 1997, Volume: 87, Issue:4

    Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Pro

1997
Proton MR spectroscopy of delayed cerebral radiation in monkeys and humans after brachytherapy.
    AJNR. American journal of neuroradiology, 1997, Volume: 18, Issue:9

    Topics: Adult; Animals; Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Cranial Irradiation;

1997
Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings.
    International journal of radiation oncology, biology, physics, 1999, Oct-01, Volume: 45, Issue:3

    Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy

1999
Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy.
    Journal of neurosurgery, 1999, Volume: 91, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Nuclear; Biomarkers, Tumor; Brain; Cell Division; Cell Tra

1999
Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation.
    The Journal of biological chemistry, 2000, Jun-16, Volume: 275, Issue:24

    Topics: Animals; Blood; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Choline; Cytidine Diphosph

2000
Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; Aziridines; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cu

2000
Quantification of microheterogeneity in glioblastoma multiforme with ex vivo high-resolution magic-angle spinning (HRMAS) proton magnetic resonance spectroscopy.
    Neuro-oncology, 2000, Volume: 2, Issue:2

    Topics: Adult; Biopsy; Brain Neoplasms; Choline; Glioblastoma; Gliosis; Humans; Lactates; Lipids; Magnetic R

2000
Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Apr-15, Volume: 21, Issue:8

    Topics: Animals; Apoptosis; Aziridines; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Choline; Dose-Respon

2001
In vivo single-voxel proton MR spectroscopy in brain lesions with ring-like enhancement.
    NMR in biomedicine, 2001, Volume: 14, Issue:6

    Topics: Adult; Aged; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Cerebral Infarction; Choline; Cr

2001
Effect of choline administration on the toxicity of N-nitrosodimethylamine in female rats.
    Toxicology and applied pharmacology, 1977, Volume: 42, Issue:3

    Topics: Alanine Transaminase; Animals; Choline; Dimethylnitrosamine; Female; Liver; Necrosis; Nitrosamines;

1977
Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate.
    The American journal of pathology, 1975, Volume: 81, Issue:1

    Topics: Acute Disease; Adenine; Age Factors; Animals; Choline; Choline Deficiency; Diet; Ethionine; Female;

1975
Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum.
    Gastroenterology, 1976, Volume: 70, Issue:5 PT.1

    Topics: Acute Disease; Adipose Tissue; Amylases; Animals; Body Weight; Choline; Disease Models, Animal; Enzy

1976
Mechanisms of the enhanced liver carcinogenesis by choline in female rats: delay in liver growth after partial hepatectomy and stimulation of 2-AAF mitoinhibition.
    Carcinogenesis, 1992, Volume: 13, Issue:10

    Topics: 2-Acetylaminofluorene; Animals; Cell Division; Choline; Diethylnitrosamine; DNA, Neoplasm; Drug Inte

1992
Variable involvement of rat skeletal muscles in paraoxon-induced necrotizing myopathy.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:3

    Topics: Animals; Choline; Male; Muscles; Muscular Diseases; Necrosis; Neuromuscular Junction; Paraoxon; Rats

1992
Resistance of female Fischer-344 rats to the hepatonecrogenic and hepatocarcinogenic actions of a choline-devoid diet.
    Carcinogenesis, 1991, Volume: 12, Issue:8

    Topics: Animals; Choline; Diet; Female; Liver; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Exper

1991
[Clinical study on the anti-lipidemia and anti-steatosis effectiveness of the pantetheine-phosphorylcholine pharmacologic combination].
    La Clinica terapeutica, 1986, Sep-30, Volume: 118, Issue:6

    Topics: Adult; Aged; Choline; Drug Evaluation; Drug Therapy, Combination; Fat Necrosis; Female; Humans; Hype

1986
Acute hemorrhagic pancreatitis in mice: A study of glucoregulatory hormones and glucose metabolism.
    The American journal of pathology, 1985, Volume: 118, Issue:1

    Topics: Acute Disease; Animals; Blood Glucose; Body Weight; Choline; Female; Glucagon; Glucose; Hemorrhage;

1985
Neuropathology and amphetamine-induced turning resulting from AF64A injections into the striatum of the rat.
    Life sciences, 1986, Mar-24, Volume: 38, Issue:12

    Topics: Amphetamine; Animals; Aziridines; Azirines; Behavior, Animal; Choline; Corpus Striatum; Male; Motor

1986
Effect of alcohol on the liver of rats. II. Factors contributing to elevations of plasma transaminase activities and hepatic cell necrosis following a single administration of alcohol in rats.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:5

    Topics: Alcohols; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury

1969
Cardiac lesions in C mice. Result of choline-deficient and choline-supplemented diets.
    Archives of pathology, 1968, Volume: 85, Issue:5

    Topics: Animals; Calcinosis; Choline; Choline Deficiency; Coronary Vessels; Fibroblasts; Heart Atria; Heart

1968
Methionine-responsive liver damage in young pigs fed a diet low in protien and vitamin E.
    The Journal of nutrition, 1968, Volume: 95, Issue:4

    Topics: Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Choline; Diet; Fatty Liver; Femal

1968
Prevention of renal necrosis by coconut oil in choline-deficient rats.
    Archives of pathology, 1966, Volume: 81, Issue:1

    Topics: Animals; Choline; Choline Deficiency; Cocos; Deficiency Diseases; Kidney Diseases; Necrosis; Oils; R

1966
Fatty cirrhosis in the rat.
    Archives of pathology, 1966, Volume: 81, Issue:6

    Topics: Animals; Autoradiography; Bile Ducts; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Choline; Fats;

1966