choline has been researched along with Necrosis in 59 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Excerpt | Relevance | Reference |
---|---|---|
"This meta-analysis indicated 11C-choline has high diagnostic accuracy for the identification of tumor relapse from radiation induced necrosis in gliomas." | 8.98 | Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis. ( Chen, G; Gao, L; Li, T; Xu, W; Zheng, J, 2018) |
"The aim of this study is to assess the different metabolic activities characteristic of glioma recurrence and radiation necrosis (RN) and to explore the diagnostic accuracy for differentiation of the two conditions using (11)C-methionine (MET), (11)C-choline (CHO), and (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)." | 7.80 | Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis. ( Asano, Y; Iwama, T; Miwa, K; Nomura, Y; Shinoda, J; Takenaka, S; Yano, H; Yonezawa, S, 2014) |
"Weanling rats fed a choline-deficient diet develop kidney oxidative damage, tubular and cortical kidney necrosis, renal failure and animal death." | 7.79 | The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency. ( Boveris, A; Monserrat, AJ; Ossani, GP; Repetto, MG, 2013) |
"To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy." | 7.77 | Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy. ( Chen, L; Guan, Y; Lin, X; Tan, H, 2011) |
"The influence of several factors on the development of acute hemorrhagic pancreatitis (pancreatic necrosis) with fat necrosis in mice fed DL-ethionine with a choline-deficient diet has been investigated." | 7.65 | Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. ( Lombardi, B; Rao, NK, 1975) |
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 5.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
"This meta-analysis indicated 11C-choline has high diagnostic accuracy for the identification of tumor relapse from radiation induced necrosis in gliomas." | 4.98 | Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis. ( Chen, G; Gao, L; Li, T; Xu, W; Zheng, J, 2018) |
" This biochemical information can be processed and presented as density maps of several metabolites, among them N-acetylaspartate (marker of neuronal viability), choline (marker of membrane turnover), creatine (related to the energy state of the cells), myo-Inositol (exclusively found in astrocytes), lipids and lactate (observed in necrosis and other pathological processes) which mean relevant information in the context of brain tumors." | 4.85 | Proton magnetic resonance spectroscopy imaging in the study of human brain cancer. ( Celda, B; Martínez-Bisbal, MC, 2009) |
"The aim of this study is to assess the different metabolic activities characteristic of glioma recurrence and radiation necrosis (RN) and to explore the diagnostic accuracy for differentiation of the two conditions using (11)C-methionine (MET), (11)C-choline (CHO), and (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)." | 3.80 | Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis. ( Asano, Y; Iwama, T; Miwa, K; Nomura, Y; Shinoda, J; Takenaka, S; Yano, H; Yonezawa, S, 2014) |
"Weanling rats fed a choline-deficient diet develop kidney oxidative damage, tubular and cortical kidney necrosis, renal failure and animal death." | 3.79 | The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency. ( Boveris, A; Monserrat, AJ; Ossani, GP; Repetto, MG, 2013) |
"To compare metabolic magnetic resonance (MR) imaging findings (ie, quantification of tumor choline concentration) with percentage of necrosis on pathologic examination in rabbits bearing VX2 liver tumors." | 3.77 | Quantitative proton MR spectroscopy as a biomarker of tumor necrosis in the rabbit VX2 liver tumor. ( Buijs, M; Geschwind, JF; Kamel, IR; Lee, KH; Liapi, E; Pan, L; Salibi, N; Ventura, VP; Vossen, JA, 2011) |
"To compare potentials of magnetic resonance imaging (MRI), F-18 FDG, and 11C-Choline PET/CT in differentiating brain tumor recurrence from necrosis after radiotherapy." | 3.77 | Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy. ( Chen, L; Guan, Y; Lin, X; Tan, H, 2011) |
"The influence of several factors on the development of acute hemorrhagic pancreatitis (pancreatic necrosis) with fat necrosis in mice fed DL-ethionine with a choline-deficient diet has been investigated." | 3.65 | Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate. ( Lombardi, B; Rao, NK, 1975) |
"A new experimental model has been found whereby acute hemorrhagic pancreatic necrosis with fat necrosis is induced in 100% of young female mice fed a choline-deficient diet supplemented with 0." | 3.65 | Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum. ( Lombardi, B; Rao, KN; Tuma, J, 1976) |
"Postradiation treatment necrosis is one of the most serious late sequelae and appears within 6 months." | 3.01 | Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis. ( Aseel, A; McCarthy, P; Mohammed, A, 2023) |
"necrosis in patients with primary brain tumors or brain metastasis." | 2.53 | Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis. ( Chen, YC; Chuang, MT; Liu, YS; Tsai, YS; Wang, CK, 2016) |
"The histological diagnosis was anaplastic oligodendroglioma (WHO grade III)." | 1.37 | [Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma]. ( Akutsu, H; Anno, I; Isobe, T; Masumoto, T; Matsumura, A; Nakai, K; Shiigai, M; Takano, S; Yamamoto, T, 2011) |
"Choline (Cho) was increased in 3 (11%), normal in 4 (14%), and reduced in 21 (75%) spectra." | 1.30 | Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings. ( Aw, YS; Chong, VF; Chua, EJ; Fan, YF; Ho, GL; Rumpel, H, 1999) |
"Necrosis was present histologically in four of the five meningiomas classified either as atypical or papillary." | 1.30 | Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy. ( Handa, J; Inubushi, T; Matsuda, M; Morikawa, S; Nakasu, S; Shino, A, 1999) |
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis." | 1.29 | Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994) |
"The necrosis was most pronounced in the predominantly oxidative-rich fiber-composed diaphragm." | 1.28 | Variable involvement of rat skeletal muscles in paraoxon-induced necrotizing myopathy. ( De Bleecker, JL; De Reuck, JL; van den Abeele, KG, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (23.73) | 18.7374 |
1990's | 11 (18.64) | 18.2507 |
2000's | 11 (18.64) | 29.6817 |
2010's | 19 (32.20) | 24.3611 |
2020's | 4 (6.78) | 2.80 |
Authors | Studies |
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Feng, A | 1 |
Yuan, P | 1 |
Huang, T | 1 |
Li, L | 1 |
Lyu, J | 1 |
Aseel, A | 1 |
McCarthy, P | 1 |
Mohammed, A | 1 |
Fuentes-Baile, M | 1 |
Bello-Gil, D | 1 |
Pérez-Valenciano, E | 1 |
Sanz, JM | 1 |
García-Morales, P | 1 |
Maestro, B | 1 |
Ventero, MP | 1 |
Alenda, C | 1 |
Barberá, VM | 1 |
Saceda, M | 1 |
Wang, AP | 1 |
Suryavanshi, T | 1 |
Marcucci, M | 1 |
Fong, C | 1 |
Whitton, AC | 1 |
Reddy, KKV | 1 |
Gao, L | 1 |
Xu, W | 2 |
Li, T | 1 |
Zheng, J | 1 |
Chen, G | 1 |
Fedele, TA | 1 |
Galdos-Riveros, AC | 1 |
Jose de Farias e Melo, H | 1 |
Magalhães, A | 1 |
Maria, DA | 1 |
Takeuchi, M | 1 |
Matsuzaki, K | 1 |
Harada, M | 1 |
Denninghoff, V | 1 |
Ossani, G | 1 |
Uceda, A | 1 |
Rugnone, M | 1 |
Fernández, E | 1 |
Fresno, C | 1 |
González, G | 1 |
Díaz, ML | 1 |
Avagnina, A | 1 |
Elsner, B | 1 |
Monserrat, A | 1 |
Hemminki, O | 1 |
Immonen, R | 1 |
Närväinen, J | 1 |
Kipar, A | 1 |
Paasonen, J | 1 |
Jokivarsi, KT | 1 |
Yli-Ollila, H | 1 |
Soininen, P | 1 |
Partanen, K | 1 |
Joensuu, T | 1 |
Parvianen, S | 1 |
Pesonen, SK | 1 |
Koski, A | 1 |
Vähä-Koskela, M | 1 |
Cerullo, V | 1 |
Pesonen, S | 1 |
Gröhn, OH | 1 |
Hemminki, A | 1 |
Takenaka, S | 1 |
Asano, Y | 1 |
Shinoda, J | 1 |
Nomura, Y | 1 |
Yonezawa, S | 1 |
Miwa, K | 1 |
Yano, H | 1 |
Iwama, T | 1 |
Bolcaen, J | 2 |
Descamps, B | 2 |
Deblaere, K | 2 |
Boterberg, T | 2 |
De Vos Pharm, F | 1 |
Kalala, JP | 2 |
Van den Broecke, C | 2 |
Decrock, E | 1 |
Leybaert, L | 1 |
Vanhove, C | 2 |
Goethals, I | 2 |
Chuang, MT | 1 |
Liu, YS | 1 |
Tsai, YS | 1 |
Chen, YC | 1 |
Wang, CK | 1 |
Gautheron, J | 1 |
Vucur, M | 1 |
Schneider, AT | 1 |
Severi, I | 1 |
Roderburg, C | 1 |
Roy, S | 1 |
Bartneck, M | 1 |
Schrammen, P | 1 |
Diaz, MB | 1 |
Ehling, J | 1 |
Gremse, F | 1 |
Heymann, F | 1 |
Koppe, C | 1 |
Lammers, T | 1 |
Kiessling, F | 1 |
Van Best, N | 1 |
Pabst, O | 1 |
Courtois, G | 1 |
Linkermann, A | 1 |
Krautwald, S | 1 |
Neumann, UP | 1 |
Tacke, F | 1 |
Trautwein, C | 1 |
Green, DR | 1 |
Longerich, T | 1 |
Frey, N | 1 |
Luedde, M | 1 |
Bluher, M | 1 |
Herzig, S | 1 |
Heikenwalder, M | 1 |
Luedde, T | 1 |
Lybaert, K | 1 |
Moerman, L | 1 |
De Vos, F | 1 |
Ben-Arie, G | 1 |
Serlin, Y | 1 |
Ivens, S | 1 |
Benifla, M | 1 |
Cagnano, E | 1 |
Melamed, I | 1 |
Merkin, V | 1 |
Shelef, I | 1 |
McLean, AS | 1 |
Huang, SJ | 1 |
Salter, M | 1 |
Nakajima, T | 1 |
Kumabe, T | 1 |
Kanamori, M | 1 |
Saito, R | 2 |
Tashiro, M | 1 |
Watanabe, M | 1 |
Tominaga, T | 1 |
Martínez-Bisbal, MC | 1 |
Celda, B | 1 |
Matoba, M | 1 |
Kondou, T | 1 |
Tanaka, T | 2 |
Kitadate, M | 1 |
Oota, K | 1 |
Tonami, H | 1 |
Isobe, T | 1 |
Akutsu, H | 1 |
Yamamoto, T | 1 |
Shiigai, M | 1 |
Masumoto, T | 1 |
Nakai, K | 1 |
Takano, S | 1 |
Anno, I | 1 |
Matsumura, A | 1 |
Buijs, M | 1 |
Vossen, JA | 1 |
Geschwind, JF | 1 |
Salibi, N | 1 |
Pan, L | 1 |
Ventura, VP | 1 |
Liapi, E | 1 |
Lee, KH | 1 |
Kamel, IR | 1 |
Tan, H | 1 |
Chen, L | 1 |
Guan, Y | 1 |
Lin, X | 1 |
Benitez, D | 1 |
Pezaroglo, H | 1 |
Martínez, V | 1 |
Casanova, G | 1 |
Cabrera, G | 1 |
Galanti, N | 1 |
González, M | 1 |
Cerecetto, H | 1 |
Lu, L | 1 |
Ni, J | 1 |
Zhou, T | 1 |
Fenech, M | 1 |
Wang, X | 1 |
Gaze, DC | 1 |
Ossani, GP | 1 |
Repetto, MG | 1 |
Boveris, A | 1 |
Monserrat, AJ | 1 |
Rock, JP | 1 |
Hearshen, D | 1 |
Scarpace, L | 1 |
Croteau, D | 1 |
Gutierrez, J | 1 |
Fisher, JL | 1 |
Rosenblum, ML | 1 |
Mikkelsen, T | 1 |
KLATSKIN, G | 1 |
KREHL, WA | 1 |
BAXTER, JH | 1 |
GOODMAN, H | 1 |
Herynek, V | 1 |
Burian, M | 1 |
Jirák, D | 1 |
Liscák, R | 1 |
Námestková, K | 1 |
Hájek, M | 1 |
Syková, E | 1 |
Sarri, E | 1 |
Garcia-Dorado, D | 1 |
Abellan, A | 1 |
Soler-Soler, J | 1 |
Giambarresi, LI | 1 |
Katyal, SL | 1 |
Lombardi, B | 4 |
Sijens, PE | 1 |
van Dijk, P | 1 |
Oudkerk, M | 1 |
Thielemann, LE | 1 |
Rodrigo, RA | 1 |
Oberhauser, EW | 1 |
Rosenblut, G | 1 |
Videla, LA | 1 |
Tracey, I | 1 |
Dunn, JF | 1 |
Parkes, HG | 1 |
Radda, GK | 1 |
Wald, LL | 1 |
Nelson, SJ | 1 |
Day, MR | 1 |
Noworolski, SE | 1 |
Henry, RG | 1 |
Huhn, SL | 1 |
Chang, S | 1 |
Prados, MD | 1 |
Sneed, PK | 1 |
Larson, DA | 1 |
Wara, WM | 1 |
McDermott, M | 1 |
Dillon, WP | 1 |
Gutin, PH | 1 |
Vigneron, DB | 1 |
Kinoshita, K | 1 |
Tada, E | 1 |
Matsumoto, K | 1 |
Asari, S | 1 |
Ohmoto, T | 1 |
Itoh, T | 1 |
Chong, VF | 1 |
Rumpel, H | 1 |
Aw, YS | 1 |
Ho, GL | 1 |
Fan, YF | 1 |
Chua, EJ | 1 |
Shino, A | 1 |
Nakasu, S | 1 |
Matsuda, M | 1 |
Handa, J | 1 |
Morikawa, S | 1 |
Inubushi, T | 1 |
Gasull, T | 1 |
DeGregorio-Rocasolano, N | 1 |
Zapata, A | 1 |
Trullas, R | 1 |
Harms, C | 2 |
Lautenschlager, M | 2 |
Bergk, A | 2 |
Freyer, D | 2 |
Weih, M | 1 |
Dirnagl, U | 2 |
Weber, JR | 2 |
Hörtnagl, H | 2 |
Cheng, LL | 1 |
Anthony, DC | 1 |
Comite, AR | 1 |
Black, PM | 1 |
Tzika, AA | 1 |
Gonzalez, RG | 1 |
Katchanov, J | 1 |
Kapinya, K | 1 |
Herwig, U | 1 |
Megow, D | 1 |
Kimura, T | 1 |
Sako, K | 1 |
Gotoh, T | 1 |
Tanaka, K | 1 |
Pani, P | 2 |
Columbano, A | 1 |
Dessi, S | 1 |
Porcu, M | 1 |
Ledda, GM | 1 |
Diaz, G | 1 |
Rao, NK | 1 |
Rao, KN | 3 |
Tuma, J | 1 |
Bernsen, HJ | 1 |
Heerschap, A | 1 |
van der Kogel, AJ | 1 |
van Vaals, JJ | 1 |
Prick, MJ | 1 |
Poels, EF | 1 |
Meyer, J | 1 |
Grotenhuis, JA | 1 |
Tessitore, L | 1 |
Dianzani, MU | 1 |
De Bleecker, JL | 1 |
van den Abeele, KG | 1 |
De Reuck, JL | 1 |
Palomba, L | 1 |
Coto, V | 1 |
Oliviero, U | 1 |
Lucariello, A | 1 |
Cerini, R | 1 |
Cocozza, M | 1 |
Cacciatore, L | 1 |
Porfido, FA | 1 |
Lingetti, M | 1 |
Scarpellino, F | 1 |
Talarico, M | 1 |
Virji, MA | 1 |
Stwertka, SA | 1 |
Olson, GL | 1 |
Takeuchi, J | 1 |
Takada, A | 1 |
Kanayama, R | 1 |
Ohara, N | 1 |
Okumura, Y | 1 |
Thomas, HM | 1 |
Williams, WL | 1 |
Clower, BR | 1 |
Reid, IM | 1 |
Barnes, RH | 1 |
Pond, WG | 1 |
Krook, L | 1 |
Zaki, FG | 1 |
Hoffbauer, FW | 1 |
Grande, F | 1 |
Zaki, GF | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Multi-paramEtric Imaging to Assess Treatment REsponse After Stereotactic Radiosurgery of Brain Metastases[NCT04626206] | 12 participants (Anticipated) | Observational | 2020-12-31 | Not yet recruiting | |||
Combination of 11C-MET PET and MRS in the Diagnosis of Glioma.[NCT03009318] | 100 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
6 reviews available for choline and Necrosis
Article | Year |
---|---|
Brain magnetic resonance spectroscopy to differentiate recurrent neoplasm from radiation necrosis: A systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Neoplasms; Child; Child, Preschool; Choline; Cr | 2023 |
Accuracy of 11C-choline positron emission tomography in differentiating glioma recurrence from radiation necrosis: A systematic review and meta-analysis.
Topics: Carbon Radioisotopes; Choline; Diagnosis, Differential; Glioma; Humans; Necrosis; Neoplasm Recurrenc | 2018 |
Differentiating Radiation-Induced Necrosis from Recurrent Brain Tumor Using MR Perfusion and Spectroscopy: A Meta-Analysis.
Topics: Aspartic Acid; Blood Volume; Brain; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Hum | 2016 |
Bench-to-bedside review: the value of cardiac biomarkers in the intensive care patient.
Topics: Biomarkers; CA-125 Antigen; Cardiovascular Diseases; CD40 Ligand; Choline; Creatine Kinase, MB Form; | 2008 |
Proton magnetic resonance spectroscopy imaging in the study of human brain cancer.
Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Creatinine; Glioblastoma; Humans; In | 2009 |
Image-guided 1H NMR spectroscopical and histological characterization of a human brain tumor model in the nude rat; a new approach to monitor changes in tumor metabolism.
Topics: Animals; Aspartic Acid; Brain Neoplasms; Choline; Energy Metabolism; Glioblastoma; Humans; Lactates; | 1992 |
53 other studies available for choline and Necrosis
Article | Year |
---|---|
Distinguishing Tumor Recurrence From Radiation Necrosis in Treated Glioblastoma Using Multiparametric MRI.
Topics: Brain Neoplasms; Choline; Creatine; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; | 2022 |
CLytA-DAAO, Free and Immobilized in Magnetic Nanoparticles, induces Cell Death in Human Cancer Cells.
Topics: 3T3-L1 Cells; Adenocarcinoma; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; | 2020 |
Radiation Necrosis Following Stereotactic Radiosurgery for Trigeminal Neuralgia.
Topics: Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnostic Err | 2020 |
Prognostic relationship of metabolic profile obtained of melanoma B16F10.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; | 2013 |
Preliminary observations and clinical value of lipid peak in high-grade uterine sarcomas using in vivo proton MR spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Choline; Female; Humans; Leiomyoma; Lipids; Magnetic Resonance Spect | 2013 |
Molecular pathology of acute kidney injury in a choline-deficient model and fish oil protective effect.
Topics: Acute Kidney Injury; Animals; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Fish Oil | 2014 |
In vivo magnetic resonance imaging and spectroscopy identifies oncolytic adenovirus responders.
Topics: Adenoviridae; Animals; Biomarkers, Tumor; Carcinoma; Cells, Cultured; Choline; Cricetinae; Fatty Aci | 2014 |
Comparison of (11)C-methionine, (11)C-choline, and (18)F-fluorodeoxyglucose-PET for distinguishing glioma recurrence from radiation necrosis.
Topics: Adult; Aged; Area Under Curve; Brain; Brain Neoplasms; Carbon Isotopes; Choline; Combined Modality T | 2014 |
(18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Choline; Diagnosis, Differential; Female; Fluorodeoxyglu | 2015 |
The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance.
Topics: Adipocytes; Adipose Tissue, White; Animals; Apoptosis; Body Mass Index; Caspase 8; Choline; Choline | 2016 |
Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination between High-Grade Glioma and Radiation Necrosis in Rats.
Topics: Animals; Brain; Cell Line, Tumor; Choline; Diagnosis, Differential; Disease Models, Animal; Female; | 2016 |
Diagnosing necrotic meningioma: a distinctive imaging pattern in diffusion MRI and MR spectroscopy.
Topics: Choline; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Female; Glutamic Acid; Gluta | 2017 |
Differential diagnosis between radiation necrosis and glioma progression using sequential proton magnetic resonance spectroscopy and methionine positron emission tomography.
Topics: Adolescent; Adult; Aged; Biomarkers; Brain; Brain Neoplasms; Carbon Radioisotopes; Choline; Diagnosi | 2009 |
Noninvasive monitoring of radiation-induced early therapeutic response using high-resolution MR imaging and proton MR spectroscopy in VX2 carcinoma.
Topics: Animals; Choline; Creatine; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy | 2010 |
[Usefulness of quantitative H-MR spectroscopy for the differentiation between radiation necrosis and recurrence of anaplastic oligodendroglioma].
Topics: Adult; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; F | 2011 |
Quantitative proton MR spectroscopy as a biomarker of tumor necrosis in the rabbit VX2 liver tumor.
Topics: Animals; Choline; Liver Neoplasms, Experimental; Magnetic Resonance Spectroscopy; Necrosis; Rabbits; | 2011 |
Comparison of MRI, F-18 FDG, and 11C-choline PET/CT for their potentials in differentiating brain tumor recurrence from brain tumor necrosis following radiotherapy.
Topics: Adult; Aged; Brain; Brain Neoplasms; Choline; Diagnosis, Differential; Female; Fluorodeoxyglucose F1 | 2011 |
Study of Trypanosoma cruzi epimastigote cell death by NMR-visible mobile lipid analysis.
Topics: Animals; Apoptosis; Autophagy; Cell Death; Choline; Hydrogen Peroxide; Lipids; Magnetic Resonance Sp | 2012 |
Choline and/or folic acid deficiency is associated with genomic damage and cell death in human lymphocytes in vitro.
Topics: Adult; Apoptosis; Cell Death; Cell Nucleus; Cells, Cultured; Choline; Choline Deficiency; DNA Damage | 2012 |
Novel biomarkers of cardiac ischemia: where are we at?
Topics: Albumins; Biomarkers; Choline; Fatty Acids, Nonesterified; Humans; Myocardial Ischemia; Necrosis; Tr | 2012 |
The protective effect of menhaden oil in the oxidative damage and renal necrosis due to dietary choline deficiency.
Topics: Acute Disease; Animals; Choline; Choline Deficiency; Corn Oil; Creatinine; Diet; Dietary Supplements | 2013 |
Correlations between magnetic resonance spectroscopy and image-guided histopathology, with special attention to radiation necrosis.
Topics: Adult; Brain Neoplasms; Choline; Creatine; Diagnosis, Differential; Glioma; Humans; Lactic Acid; Lip | 2002 |
The effect of alcohol on the choline requirement. II. Incidence of renal necrosis in weanling rats following short term ingestion of alcohol.
Topics: Animals; Choline; Diet; Ethanol; Incidence; Kidney Diseases; Necrosis; Rats | 1954 |
Renal and hepatic lipid alterations in choline deficiency: relationship to renal necrosis.
Topics: Choline; Choline Deficiency; Kidney; Kidney Diseases; Lipid Metabolism; Lipids; Necrosis | 1955 |
Metabolite and diffusion changes in the rat brain after Leksell Gamma Knife irradiation.
Topics: Analysis of Variance; Animals; Aspartic Acid; Choline; Creatine; Hippocampus; Lactic Acid; Magnetic | 2004 |
Effects of hypoxia, glucose deprivation and acidosis on phosphatidylcholine synthesis in HL-1 cardiomyocytes. CTP:phosphocholine cytidylyltransferase activity correlates with sarcolemmal disruption.
Topics: Acidosis; Cell Hypoxia; Cell Line; Choline; Choline-Phosphate Cytidylyltransferase; Glucose; Hydroge | 2006 |
Promotion of liver carcinogenesis in the rat by a choline-devoid diet: role of liver cell necrosis and regeneration.
Topics: Animals; Choline; Diet; DNA; Liver; Liver Neoplasms; Liver Regeneration; Male; Necrosis; Neoplasms, | 1982 |
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin | 1994 |
N-acetyl-L-cysteine abolishes the bromoethylamine-induced choline incorporation into renal papillary tissue.
Topics: Acetylcysteine; Animals; Choline; Ethylamines; Female; Free Radical Scavengers; Kidney Medulla; Lyso | 1995 |
An in vivo and in vitro H-magnetic resonance spectroscopy study of mdx mouse brain: abnormal development or neural necrosis?
Topics: Animals; Aspartic Acid; Astrocytes; Brain; Brain Chemistry; Choline; Creatine; Dystrophin; Female; G | 1996 |
Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy.
Topics: Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Contrast Media; Creatine; Disease Pro | 1997 |
Proton MR spectroscopy of delayed cerebral radiation in monkeys and humans after brachytherapy.
Topics: Adult; Animals; Aspartic Acid; Brachytherapy; Brain; Brain Neoplasms; Choline; Cranial Irradiation; | 1997 |
Temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma: 1H MR spectroscopic findings.
Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Humans; Magnetic Resonance Spectroscopy | 1999 |
Noninvasive evaluation of the malignant potential of intracranial meningiomas performed using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Nuclear; Biomarkers, Tumor; Brain; Cell Division; Cell Tra | 1999 |
Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation.
Topics: Animals; Blood; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Choline; Cytidine Diphosph | 2000 |
Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures.
Topics: Animals; Antioxidants; Apoptosis; Aziridines; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cu | 2000 |
Quantification of microheterogeneity in glioblastoma multiforme with ex vivo high-resolution magic-angle spinning (HRMAS) proton magnetic resonance spectroscopy.
Topics: Adult; Biopsy; Brain Neoplasms; Choline; Glioblastoma; Gliosis; Humans; Lactates; Lipids; Magnetic R | 2000 |
Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration.
Topics: Animals; Apoptosis; Aziridines; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Choline; Dose-Respon | 2001 |
In vivo single-voxel proton MR spectroscopy in brain lesions with ring-like enhancement.
Topics: Adult; Aged; Brain; Brain Abscess; Brain Diseases; Brain Neoplasms; Cerebral Infarction; Choline; Cr | 2001 |
Effect of choline administration on the toxicity of N-nitrosodimethylamine in female rats.
Topics: Alanine Transaminase; Animals; Choline; Dimethylnitrosamine; Female; Liver; Necrosis; Nitrosamines; | 1977 |
Acute hemorrhagic pancreatic necrosis in mice. Influence of the age and sex of the animals and of dietary ethionine, choline, methionine, and adenine sulfate.
Topics: Acute Disease; Adenine; Age Factors; Animals; Choline; Choline Deficiency; Diet; Ethionine; Female; | 1975 |
Acute hemorrhagic pancreatic necrosis in mice. Intraparenchymal activation of zymogens, and other enzyme changes in pancreas and serum.
Topics: Acute Disease; Adipose Tissue; Amylases; Animals; Body Weight; Choline; Disease Models, Animal; Enzy | 1976 |
Mechanisms of the enhanced liver carcinogenesis by choline in female rats: delay in liver growth after partial hepatectomy and stimulation of 2-AAF mitoinhibition.
Topics: 2-Acetylaminofluorene; Animals; Cell Division; Choline; Diethylnitrosamine; DNA, Neoplasm; Drug Inte | 1992 |
Variable involvement of rat skeletal muscles in paraoxon-induced necrotizing myopathy.
Topics: Animals; Choline; Male; Muscles; Muscular Diseases; Necrosis; Neuromuscular Junction; Paraoxon; Rats | 1992 |
Resistance of female Fischer-344 rats to the hepatonecrogenic and hepatocarcinogenic actions of a choline-devoid diet.
Topics: Animals; Choline; Diet; Female; Liver; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Exper | 1991 |
[Clinical study on the anti-lipidemia and anti-steatosis effectiveness of the pantetheine-phosphorylcholine pharmacologic combination].
Topics: Adult; Aged; Choline; Drug Evaluation; Drug Therapy, Combination; Fat Necrosis; Female; Humans; Hype | 1986 |
Acute hemorrhagic pancreatitis in mice: A study of glucoregulatory hormones and glucose metabolism.
Topics: Acute Disease; Animals; Blood Glucose; Body Weight; Choline; Female; Glucagon; Glucose; Hemorrhage; | 1985 |
Neuropathology and amphetamine-induced turning resulting from AF64A injections into the striatum of the rat.
Topics: Amphetamine; Animals; Aziridines; Azirines; Behavior, Animal; Choline; Corpus Striatum; Male; Motor | 1986 |
Effect of alcohol on the liver of rats. II. Factors contributing to elevations of plasma transaminase activities and hepatic cell necrosis following a single administration of alcohol in rats.
Topics: Alcohols; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury | 1969 |
Cardiac lesions in C mice. Result of choline-deficient and choline-supplemented diets.
Topics: Animals; Calcinosis; Choline; Choline Deficiency; Coronary Vessels; Fibroblasts; Heart Atria; Heart | 1968 |
Methionine-responsive liver damage in young pigs fed a diet low in protien and vitamin E.
Topics: Animals; Aspartate Aminotransferases; Blood Proteins; Body Weight; Choline; Diet; Fatty Liver; Femal | 1968 |
Prevention of renal necrosis by coconut oil in choline-deficient rats.
Topics: Animals; Choline; Choline Deficiency; Cocos; Deficiency Diseases; Kidney Diseases; Necrosis; Oils; R | 1966 |
Fatty cirrhosis in the rat.
Topics: Animals; Autoradiography; Bile Ducts; Bile Ducts, Intrahepatic; Carbon Tetrachloride; Choline; Fats; | 1966 |