choline has been researched along with Motor Neuron Disease in 4 studies
Motor Neuron Disease: Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In these patients spasticity began in the legs and progressed slowly and steadily." | 1.32 | Primary lateral sclerosis: A heterogeneous disorder composed of different subtypes? ( Butman, JA; Floeter, MK; Pagan, F; Statland, J; Zhai, P, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nelles, M | 1 |
| Block, W | 1 |
| Träber, F | 1 |
| Wüllner, U | 1 |
| Schild, HH | 1 |
| Urbach, H | 1 |
| Zhai, P | 1 |
| Pagan, F | 1 |
| Statland, J | 1 |
| Butman, JA | 1 |
| Floeter, MK | 1 |
| Wang, S | 1 |
| Poptani, H | 1 |
| Woo, JH | 1 |
| Desiderio, LM | 1 |
| Elman, LB | 1 |
| McCluskey, LF | 1 |
| Krejza, J | 1 |
| Melhem, ER | 1 |
| Schuff, N | 1 |
| Rooney, WD | 1 |
| Miller, R | 1 |
| Gelinas, DF | 1 |
| Amend, DL | 1 |
| Maudsley, AA | 1 |
| Weiner, MW | 1 |
4 other studies available for choline and Motor Neuron Disease
| Article | Year |
|---|---|
Combined 3T diffusion tensor tractography and 1H-MR spectroscopy in motor neuron disease.
Topics: Adult; Aged; Anisotropy; Aspartic Acid; Brain; Bulbo-Spinal Atrophy, X-Linked; Choline; Diagnosis, D | 2008 |
Primary lateral sclerosis: A heterogeneous disorder composed of different subtypes?
Topics: Adult; Aspartic Acid; Atrophy; Brain Stem; Choline; Creatinine; Disease Progression; Evoked Potentia | 2003 |
Amyotrophic lateral sclerosis: diffusion-tensor and chemical shift MR imaging at 3.0 T.
Topics: Adult; Age Factors; Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Choline; Creatine; Diffusion | 2006 |
Reanalysis of multislice (1)H MRSI in amyotrophic lateral sclerosis.
Topics: Adult; Aged; Aspartic Acid; Brain; Choline; Creatine; Energy Metabolism; Female; Humans; Image Proce | 2001 |