choline has been researched along with Metabolic Syndrome in 15 studies
Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS)." | 9.51 | Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome. ( Blesso, CN; Caudill, M; Cooperstone, JL; DiBella, M; Fernandez, ML; Malysheva, O; Sholola, M; Thomas, MS, 2022) |
| "Humans eating low-choline diets develop fatty liver and liver damage." | 8.88 | Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. ( Corbin, KD; Zeisel, SH, 2012) |
| "We investigated the relationships between serum choline and betaine levels with metabolic syndrome-related indices in the general population of Newfoundland." | 7.91 | Low serum choline and high serum betaine levels are associated with favorable components of metabolic syndrome in Newfoundland population. ( Gao, X; Randell, E; Sun, G; Tian, Y; Zhou, H, 2019) |
| "Choline is an important metabolite involved in phospholipids synthesis, including serum lipids, and is the immediate precursor of betaine." | 5.91 | Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults. ( Abbasi, MSP; Ardekani, AM; Gharebakhshi, F; Jafarzadeh, F; Manzouri, A; Nikrad, N; Tousi, AZ; Vahdat, S; Yazdani, Y, 2023) |
| "We previously demonstrated that intake of three eggs/d for 4 weeks increased plasma choline and decreased inflammation in subjects with metabolic syndrome (MetS)." | 5.51 | Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome. ( Blesso, CN; Caudill, M; Cooperstone, JL; DiBella, M; Fernandez, ML; Malysheva, O; Sholola, M; Thomas, MS, 2022) |
| " We hypothesized that the addition of two eggs per day would increase HDL cholesterol as well as plasma lutein, zeaxanthin and choline in individuals with metabolic syndrome (MetS)." | 5.51 | Eggs Improve Plasma Biomarkers in Patients with Metabolic Syndrome Following a Plant-Based Diet-A Randomized Crossover Study. ( Caudill, MA; Cooperstone, JL; Fernandez, ML; Malysheva, O; Puglisi, M; Sholola, M; Thomas, MS, 2022) |
| "Betaine was inversely associated with serum non-HDL cholesterol, triglycerides, BMI, percent body fat, waist circumference, systolic and diastolic blood pressure (P < 0." | 5.35 | Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women. ( Bleie, Ø; Konstantinova, SV; Nygård, O; Tell, GS; Ueland, PM; Vollset, SE, 2008) |
| "Humans eating low-choline diets develop fatty liver and liver damage." | 4.88 | Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. ( Corbin, KD; Zeisel, SH, 2012) |
| "We investigated the relationships between serum choline and betaine levels with metabolic syndrome-related indices in the general population of Newfoundland." | 3.91 | Low serum choline and high serum betaine levels are associated with favorable components of metabolic syndrome in Newfoundland population. ( Gao, X; Randell, E; Sun, G; Tian, Y; Zhou, H, 2019) |
| "Choline is an important metabolite involved in phospholipids synthesis, including serum lipids, and is the immediate precursor of betaine." | 1.91 | Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults. ( Abbasi, MSP; Ardekani, AM; Gharebakhshi, F; Jafarzadeh, F; Manzouri, A; Nikrad, N; Tousi, AZ; Vahdat, S; Yazdani, Y, 2023) |
| "Choline was not significantly altered in MetS." | 1.48 | Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome. ( Huet, B; Jialal, I; Lent-Schochet, D; McLaughlin, M; Silva, R, 2018) |
| "Rats with the metabolic syndrome have ineffective inflammation-resolving mechanisms that represent plausible reasons for the exaggerated and persistent PCD." | 1.39 | Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome. ( Britton, SL; Chawla, A; Feng, X; Koch, LG; Matthay, MA; Maze, M; Su, X; Terrando, N; Yan, Y, 2013) |
| "Betaine was inversely associated with serum non-HDL cholesterol, triglycerides, BMI, percent body fat, waist circumference, systolic and diastolic blood pressure (P < 0." | 1.35 | Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women. ( Bleie, Ø; Konstantinova, SV; Nygård, O; Tell, GS; Ueland, PM; Vollset, SE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 5 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, MS | 3 |
| DiBella, M | 2 |
| Blesso, CN | 1 |
| Malysheva, O | 3 |
| Caudill, M | 1 |
| Sholola, M | 2 |
| Cooperstone, JL | 2 |
| Fernandez, ML | 3 |
| Puglisi, M | 1 |
| Caudill, MA | 2 |
| Poursalehi, D | 1 |
| Lotfi, K | 1 |
| Mirzaei, S | 1 |
| Asadi, A | 1 |
| Akhlaghi, M | 1 |
| Saneei, P | 1 |
| Abbasi, MSP | 1 |
| Tousi, AZ | 1 |
| Yazdani, Y | 1 |
| Vahdat, S | 1 |
| Gharebakhshi, F | 1 |
| Nikrad, N | 1 |
| Manzouri, A | 1 |
| Ardekani, AM | 1 |
| Jafarzadeh, F | 1 |
| Alyousef, H | 1 |
| Millar, C | 1 |
| Blesso, C | 1 |
| Lent-Schochet, D | 1 |
| Silva, R | 1 |
| McLaughlin, M | 1 |
| Huet, B | 1 |
| Jialal, I | 1 |
| Joris, BR | 1 |
| Gloor, GB | 1 |
| Gao, X | 1 |
| Randell, E | 1 |
| Tian, Y | 1 |
| Zhou, H | 1 |
| Sun, G | 1 |
| Mueller, DM | 1 |
| Allenspach, M | 1 |
| Othman, A | 1 |
| Saely, CH | 1 |
| Muendlein, A | 1 |
| Vonbank, A | 1 |
| Drexel, H | 1 |
| von Eckardstein, A | 1 |
| Heikkilä, O | 1 |
| Lundbom, N | 1 |
| Timonen, M | 1 |
| Groop, PH | 1 |
| Heikkinen, S | 1 |
| Mäkimattila, S | 1 |
| Konstantinova, SV | 2 |
| Tell, GS | 2 |
| Vollset, SE | 2 |
| Ulvik, A | 1 |
| Drevon, CA | 1 |
| Ueland, PM | 2 |
| Coplan, JD | 1 |
| Abdallah, CG | 1 |
| Mathew, SJ | 1 |
| Shungu, DC | 1 |
| Mao, X | 1 |
| Smith, EL | 1 |
| Kaufman, D | 1 |
| Gorman, JM | 1 |
| Owens, MJ | 1 |
| Nemeroff, CB | 1 |
| Banerji, MA | 1 |
| Rosenblum, LA | 1 |
| Kral, JG | 1 |
| Corbin, KD | 1 |
| Zeisel, SH | 1 |
| Su, X | 1 |
| Feng, X | 1 |
| Terrando, N | 1 |
| Yan, Y | 1 |
| Chawla, A | 1 |
| Koch, LG | 1 |
| Britton, SL | 1 |
| Matthay, MA | 1 |
| Maze, M | 1 |
| Nygård, O | 1 |
| Bleie, Ø | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus[NCT04302168] | 60 participants (Anticipated) | Interventional | 2020-04-01 | Recruiting | |||
| The Impact Of Choline Administration On Oxidative Stress And Clinical Outcome Of Patients With Non-Alcoholic Fatty Liver Disease NAFLD[NCT05200156] | 100 participants (Anticipated) | Interventional | 2022-02-01 | Recruiting | |||
| Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium: A Multicenter, Randomized, Double-Blind Clinical Trail[NCT02928692] | Phase 3 | 750 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for choline and Metabolic Syndrome
| Article | Year |
|---|---|
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, | 2019 |
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression.
Topics: Animals; Choline; Disease Progression; Fatty Liver; Humans; Liver; Metabolic Syndrome; Non-alcoholic | 2012 |
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression.
Topics: Animals; Choline; Disease Progression; Fatty Liver; Humans; Liver; Metabolic Syndrome; Non-alcoholic | 2012 |
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression.
Topics: Animals; Choline; Disease Progression; Fatty Liver; Humans; Liver; Metabolic Syndrome; Non-alcoholic | 2012 |
Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression.
Topics: Animals; Choline; Disease Progression; Fatty Liver; Humans; Liver; Metabolic Syndrome; Non-alcoholic | 2012 |
3 trials available for choline and Metabolic Syndrome
| Article | Year |
|---|---|
Comparison between Egg Intake versus Choline Supplementation on Gut Microbiota and Plasma Carotenoids in Subjects with Metabolic Syndrome.
Topics: Carotenoids; Choline; Dietary Supplements; Eggs; Gastrointestinal Microbiome; Humans; Metabolic Synd | 2022 |
Eggs Improve Plasma Biomarkers in Patients with Metabolic Syndrome Following a Plant-Based Diet-A Randomized Crossover Study.
Topics: Biomarkers; Cholesterol, HDL; Choline; Cross-Over Studies; Diet; Diet, Vegetarian; Female; Glucose; | 2022 |
Choline Intake as Supplement or as a Component of Eggs Increases Plasma Choline and Reduces Interleukin-6 without Modifying Plasma Cholesterol in Participants with Metabolic Syndrome.
Topics: Adult; Aged; Cholesterol, LDL; Choline; Cross-Over Studies; Dietary Supplements; Eating; Eggs; Femal | 2020 |
10 other studies available for choline and Metabolic Syndrome
| Article | Year |
|---|---|
Association between methyl donor nutrients and metabolic health status in overweight and obese adolescents.
Topics: Adolescent; Betaine; Body Mass Index; Choline; Cross-Sectional Studies; Female; Health Status; Human | 2022 |
Dietary choline and betaine intake, cardio-metabolic risk factors and prevalence of metabolic syndrome among overweight and obese adults.
Topics: Adult; Betaine; Biomarkers; Cardiometabolic Risk Factors; Cholesterol; Choline; Diet; Eating; Humans | 2023 |
Changes to trimethylamine-N-oxide and its precursors in nascent metabolic syndrome.
Topics: Adult; Aged; Biomarkers; Carnitine; Choline; Female; Humans; Inflammation; Male; Metabolic Syndrome; | 2018 |
Low serum choline and high serum betaine levels are associated with favorable components of metabolic syndrome in Newfoundland population.
Topics: Adult; Betaine; Blood Glucose; Blood Pressure; Choline; Female; Humans; Insulin Resistance; Lipids; | 2019 |
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Cor | 2015 |
Risk for metabolic syndrome predisposes to alterations in the thalamic metabolism.
Topics: Adult; Anthropometry; Aspartic Acid; Blood Glucose; Choline; Creatine; Diabetes Mellitus, Type 2; Hu | 2008 |
Dietary patterns, food groups, and nutrients as predictors of plasma choline and betaine in middle-aged and elderly men and women.
Topics: Aged; Betaine; Bread; Cardiovascular Diseases; Choline; Cohort Studies; Diet Surveys; Dietary Fats; | 2008 |
Metabolic syndrome and neurometabolic asymmetry of hippocampus in adult bonnet monkeys.
Topics: Animals; Aspartic Acid; Blood Glucose; Choline; Corticotropin-Releasing Hormone; Creatine; Functiona | 2011 |
Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome.
Topics: Animals; Anti-Inflammatory Agents; CD3 Complex; Cell Polarity; Choline; Cognition Disorders; Disease | 2013 |
Divergent associations of plasma choline and betaine with components of metabolic syndrome in middle age and elderly men and women.
Topics: Aged; Betaine; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Body Weights and Me | 2008 |