choline has been researched along with Malaria in 19 studies
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parasitized erythrocytes from mice infected with the murine malaria parasite Plasmodium vinckei vinckei showed a marked increase in the rate of influx of choline compared with erythrocytes from uninfected mice." | 7.70 | Increased choline transport in erythrocytes from mice infected with the malaria parasite Plasmodium vinckei vinckei. ( Kirk, K; Staines, HM, 1998) |
| "Parasitized erythrocytes from mice infected with the murine malaria parasite Plasmodium vinckei vinckei showed a marked increase in the rate of influx of choline compared with erythrocytes from uninfected mice." | 3.70 | Increased choline transport in erythrocytes from mice infected with the malaria parasite Plasmodium vinckei vinckei. ( Kirk, K; Staines, HM, 1998) |
| "The permeability of simian erythrocytes to choline was found to be considerably increased after infection by the malaria parasite, Plasmodium knowlesi." | 3.68 | Increased permeability to choline in simian erythrocytes after Plasmodium knowlesi infection. ( Ancelin, ML; Parant, M; Philippot, JR; Thuet, MJ; Vial, HJ, 1991) |
| "Malaria has emerged as one of the most debilitating parasitic infection with about 500 million cases reported annually and one million deaths worldwide." | 2.47 | Novel targets for malaria therapy. ( Patravale, V; Prabhu, P, 2011) |
| " The bioavailability of a radiolabeled form of the product seemed to be advantageous (slow blood clearance and no significant concentration in tissues)." | 2.38 | Basic biochemical investigations as rationale for the design of original antimalarial drugs. An example of phospholipid metabolism. ( Angelin, ML; Calas, M; Cordinas, G; Elabbadi, N; Giral, L; Vial, HJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Ramaprasad, A | 1 |
| Burda, PC | 1 |
| Calvani, E | 1 |
| Sait, AJ | 1 |
| Palma-Duran, SA | 1 |
| Withers-Martinez, C | 1 |
| Hackett, F | 1 |
| Macrae, J | 1 |
| Collinson, L | 1 |
| Gilberger, TW | 1 |
| Blackman, MJ | 1 |
| Duan, S | 1 |
| Wang, R | 2 |
| Tang, J | 1 |
| Xiao, X | 1 |
| Li, N | 1 |
| Guo, W | 1 |
| Yang, Q | 1 |
| Ren, G | 1 |
| Zhang, S | 1 |
| Abdel-Haleem, AM | 1 |
| Hefzi, H | 1 |
| Mineta, K | 1 |
| Gao, X | 1 |
| Gojobori, T | 1 |
| Palsson, BO | 1 |
| Lewis, NE | 1 |
| Jamshidi, N | 1 |
| Tritten, L | 1 |
| Keiser, J | 1 |
| Karwa, T | 1 |
| Utzinger, J | 1 |
| Holmes, E | 1 |
| Saric, J | 1 |
| WENT, F | 1 |
| Prabhu, P | 1 |
| Patravale, V | 1 |
| Peyrottes, S | 1 |
| Caldarelli, S | 1 |
| Wein, S | 1 |
| Périgaud, C | 1 |
| Pellet, A | 1 |
| Vial, H | 1 |
| Ancelin, ML | 7 |
| Vial, HJ | 8 |
| Calas, M | 4 |
| Giral, L | 2 |
| Piquet, G | 2 |
| Rubi, E | 1 |
| Thomas, A | 1 |
| Peters, W | 1 |
| Slomianny, C | 1 |
| Herrera, S | 1 |
| Elford, BC | 3 |
| Cowan, GM | 1 |
| Ferguson, DJ | 1 |
| Elabbadi, N | 2 |
| Gumila, C | 1 |
| Bonnet, H | 1 |
| Jeong, YH | 1 |
| Philippot, J | 1 |
| Portefaix, P | 1 |
| Staines, HM | 1 |
| Kirk, K | 2 |
| Eldin, P | 1 |
| Martin, D | 1 |
| Gannoun, L | 1 |
| Angelin, ML | 1 |
| Cordinas, G | 1 |
| Poli de Figueiredo, CE | 1 |
| Ellory, JC | 2 |
| Parant, M | 1 |
| Thuet, MJ | 2 |
| Philippot, JR | 3 |
| Pinches, RA | 1 |
| Newbold, CI | 1 |
6 reviews available for choline and Malaria
| Article | Year |
|---|---|
Novel targets for malaria therapy.
Topics: Animals; Antimalarials; Choline; Cyclin-Dependent Kinases; Erythrocytes; Glucose; Humans; Malaria; M | 2011 |
Choline analogues in malaria chemotherapy.
Topics: Animals; Antimalarials; Choline; Humans; Malaria; Plasmodium malariae | 2012 |
Parasite-regulated membrane transport processes and metabolic control in malaria-infected erythrocytes.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Chloroquine; Choline; Drug Resistance, Multiple; Er | 1995 |
The design of original antimalarial drugs. An example of phospholipid metabolism.
Topics: Animals; Antimalarials; Carrier Proteins; Choline; Dogs; Drug Design; Haplorhini; Malaria; Membrane | 1993 |
Transport of phospholipid synthesis precursors and lipid trafficking into malaria-infected erythrocytes.
Topics: Animals; Biological Transport, Active; Choline; Erythrocytes; Humans; Lipid Metabolism; Malaria; Pho | 1999 |
Basic biochemical investigations as rationale for the design of original antimalarial drugs. An example of phospholipid metabolism.
Topics: Animals; Antimalarials; Carrier Proteins; Cell Line; Cholesterol; Choline; Drug Design; Drug Evaluat | 1992 |
13 other studies available for choline and Malaria
| Article | Year |
|---|---|
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite.
Topics: Animals; Choline; Erythrocytes; Glycerylphosphorylcholine; Malaria; Malaria, Falciparum; Parasites; | 2022 |
Topics: Animals; Antimalarials; Artemisinins; Choline; Liposomes; Malaria; Mice; Mice, Inbred ICR; Plasmodiu | 2020 |
Functional interrogation of Plasmodium genus metabolism identifies species- and stage-specific differences in nutrient essentiality and drug targeting.
Topics: Animals; Choline; Culicidae; Disease Models, Animal; Food; Gene Deletion; Gene Expression Regulation | 2018 |
Comparing systemic metabolic responses in mice to single or dual infection with Plasmodium berghei and Heligmosomoides bakeri.
Topics: Amino Acids; Animals; Brain; Choline; Citric Acid Cycle; Coinfection; Female; Glycolysis; Intestinal | 2014 |
Blutcholin, acetylcholine and histamine for fever treatment and malaria attack.
Topics: Acetylcholine; Blood; Choline; Fever; Histamine; Humans; Malaria | 1946 |
Present development concerning antimalarial activity of phospholipid metabolism inhibitors with special reference to in vivo activity.
Topics: Animals; Antimalarials; Choline; Drug Resistance; Host-Parasite Interactions; Humans; Lethal Dose 50 | 1994 |
Increased choline transport in erythrocytes from mice infected with the malaria parasite Plasmodium vinckei vinckei.
Topics: Animals; Biological Transport, Active; Choline; Erythrocytes; Furosemide; Humans; In Vitro Technique | 1998 |
Effect of cell age on erythrocyte choline transport: implications for the increased choline permeability of malaria-infected erythrocytes.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Choline; Erythrocyte Aging; Erythrocyte M | 1992 |
Increased permeability to choline in simian erythrocytes after Plasmodium knowlesi infection.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Choline; Erythrocytes; Ethanolamine; Etha | 1991 |
Heterogeneous and substrate-specific membrane transport pathways induced in malaria-infected erythrocytes.
Topics: Amino Acids; Animals; Biological Transport, Active; Choline; Diazooxonorleucine; Erythrocyte Membran | 1990 |
Phospholipid metabolism in Plasmodium-infected erythrocytes: guidelines for further studies using radioactive precursor incorporation.
Topics: Animals; Choline; Erythrocytes; Fatty Acids; Glycerol; Kinetics; Macaca fascicularis; Malaria; Phosp | 1989 |
Quaternary ammonium compounds efficiently inhibit Plasmodium falciparum growth in vitro by impairment of choline transport.
Topics: Animals; Biological Transport, Active; Choline; Choline Kinase; Erythrocytes; In Vitro Techniques; M | 1986 |
Inhibitors of choline transport into Plasmodium-infected erythrocytes are effective antiplasmodial compounds in vitro.
Topics: Animals; Antimalarials; Biological Transport; Choline; Choline Kinase; Erythrocytes; In Vitro Techni | 1985 |