Page last updated: 2024-10-16

choline and Leukemia

choline has been researched along with Leukemia in 8 studies

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Mechanism of the inhibitory effect of isoprenoid farnesol on cell proliferation has been studied in human acute leukemia CEM-C1 cells."3.69Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death. ( Haug, JS; Melnykovych, G; Voziyan, PA, 1995)
"The effect of morphine and cocaine on the transport of hydrolyzed nitrogen mustard (NH2-OH) and choline by peripheral blood cells of normal subjects and patients with chronic lymphocytic leukemia, acute lymphoblastic leukemia, and acute myeloblastic leukemia was determined."3.65Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro. ( Goldenberg, GJ, 1976)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BRAIER, L1
SHACTER, B1
GANSSLEN, M1
DINNING, JS1
SEAGER, LD1
PAYNE, LD1
TOTTER, JR1
Voziyan, PA2
Haug, JS1
Melnykovych, G2
Goldner, CM1
Adebodun, F1
Goldenberg, GJ1

Other Studies

8 other studies available for choline and Leukemia

ArticleYear
[Treatment of chronic leukemias with benzene and its homologues; role of choline and methionine].
    Le Sang, 1953, Volume: 24, Issue:7

    Topics: Benzene; Choline; Humans; Leukemia; Methionine; Toluene; Xylenes

1953
Choline-oxidase activity of L4946 leukemic cells of mice.
    Journal of the National Cancer Institute, 1957, Volume: 18, Issue:2

    Topics: Animals; Choline; Leukemia; Mice; Oxidation-Reduction; Oxidoreductases

1957
[Advances in the treatment of tumors, leukemia and granuloma].
    Strahlentherapie, 1950, Volume: 83, Issue:2

    Topics: Anura; Choline; Granuloma; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Neoplas

1950
The metabolism of betaine and sodium formate by leukemic mice.
    Science (New York, N.Y.), 1952, Aug-01, Volume: 116, Issue:3005

    Topics: Animals; Betaine; Biochemical Phenomena; Choline; Formates; Leukemia; Leukemia, Experimental; Mice

1952
Mechanism of farnesol cytotoxicity: further evidence for the role of PKC-dependent signal transduction in farnesol-induced apoptotic cell death.
    Biochemical and biophysical research communications, 1995, Jul-17, Volume: 212, Issue:2

    Topics: Acute Disease; Apoptosis; Cell Division; Choline; Diglycerides; DNA; Farnesol; Humans; Leukemia; Myr

1995
Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity.
    The Biochemical journal, 1993, Nov-01, Volume: 295 ( Pt 3)

    Topics: Choline; Choline-Phosphate Cytidylyltransferase; Diacylglycerol Cholinephosphotransferase; Diglyceri

1993
Phospholipid metabolism and resistance to glucocorticoid-induced apoptosis in a human leukemic cell line: a 31P-NMR study using a phosphonium analog of choline.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Apoptosis; Cell Survival; Choline; Dexamethasone; Humans; Leukemia; Magnetic Resonance Spectroscopy;

1999
Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro.
    Cancer research, 1976, Volume: 36, Issue:3

    Topics: Biological Transport; Choline; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Leuke

1976