choline has been researched along with Leukemia, Myeloid, Acute in 9 studies
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1-beta-D-Arabinofuranosylcytosine diphosphate choline was formed from 1-beta-D-arabinofuranosylcytosine (ara-C) during incubation in vitro of peripheral myeloblasts from patients with acute myelogenous leukemia and cultured cells (nonleukemic human lymphocytes, mouse lymphoma L5178Y, and HeLa); as well, 1-beta-D-arabinofuranosylcytosine diphosphate choline was formed in vivo in mouse leukemia L1210 cells and mouse liver." | 3.66 | Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in neoplastic and normal cells. ( Belch, AW; Lauzon, GJ; Paterson, AR, 1978) |
| "The effect of morphine and cocaine on the transport of hydrolyzed nitrogen mustard (NH2-OH) and choline by peripheral blood cells of normal subjects and patients with chronic lymphocytic leukemia, acute lymphoblastic leukemia, and acute myeloblastic leukemia was determined." | 3.65 | Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro. ( Goldenberg, GJ, 1976) |
| "A brain MRI suggested possible brain metastases." | 1.43 | Differences in Uptake of 18F-FDG and 11C-Choline in a Case of Acute Myeloid Leukemia. ( Lan, X; Li, J; Qin, C; Sun, X; Wu, Z, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qin, C | 1 |
| Wu, Z | 1 |
| Li, J | 1 |
| Sun, X | 1 |
| Lan, X | 1 |
| Medina, D | 1 |
| David, K | 1 |
| Lin, Y | 2 |
| Schaar, D | 2 |
| Patel, V | 1 |
| Gharibo, M | 2 |
| Bannerji, R | 1 |
| Walton, K | 1 |
| Aisner, J | 2 |
| Rabson, AB | 1 |
| Strair, R | 1 |
| Strair, RK | 1 |
| Rubin, A | 1 |
| Harrison, J | 1 |
| Lin, HC | 1 |
| Goodell, L | 1 |
| Anand, M | 1 |
| Balsara, B | 1 |
| Dudek, L | 1 |
| Rabson, A | 1 |
| Medina, DJ | 1 |
| Cooper, RA | 1 |
| Ip, SH | 1 |
| Cassileth, PA | 1 |
| Kuo, AL | 1 |
| Lauzon, GJ | 2 |
| Paran, JH | 1 |
| Paterson, AR | 2 |
| Belch, AW | 1 |
| Goldenberg, GJ | 1 |
| Stone, RM | 1 |
| Weber, BL | 1 |
| Spriggs, DR | 1 |
| Kufe, DW | 1 |
| Kiss, Z | 1 |
| Deli, E | 1 |
| Kuo, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of Nuclear Factor-kappa B (NFkB) Inhibition During Induction Chemotherapy for Patients With Acute Myelogenous Leukemia (AML)[NCT00156299] | Phase 1 | 15 participants (Actual) | Interventional | 2003-03-31 | Terminated (stopped due to Replaced by another study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for choline and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Nuclear factor-kappaB modulation in patients undergoing induction chemotherapy for acute myelogenous leukemia.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Nucleus; | 2008 |
8 other studies available for choline and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Differences in Uptake of 18F-FDG and 11C-Choline in a Case of Acute Myeloid Leukemia.
Topics: Adult; Brain Neoplasms; Choline; Fluorodeoxyglucose F18; Humans; Leukemia, Myeloid, Acute; Male; Pos | 2016 |
Choline-magnesium trisalicylate modulates acute myelogenous leukemia gene expression during induction chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Choline; Gene Expression Prof | 2017 |
Inhibition of sterol and phospholipid synthesis in HL-60 promyelocytic leukemia cells by inducers of myeloid differentiation.
Topics: Acetates; Cell Differentiation; Cell Division; Cells, Cultured; Choline; Dimethyl Sulfoxide; DNA, Ne | 1981 |
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in cultured human leukemic RPMI 6410 cells.
Topics: 3-Deazauridine; Animals; Cell Division; Cells, Cultured; Choline; Cytarabine; Cytidine Diphosphate C | 1978 |
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in neoplastic and normal cells.
Topics: 3-Deazauridine; Animals; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Female; | 1978 |
Drug-induced stimulation of transport of hydrolyzed nitrogen mustard and choline by normal and leukemic human cells in vitro.
Topics: Biological Transport; Choline; Cocaine; Dose-Response Relationship, Drug; In Vitro Techniques; Leuke | 1976 |
Phospholipase C activates protein kinase C and induces monocytic differentiation of HL-60 cells.
Topics: Cell Differentiation; Choline; Enzyme Activation; Humans; Inositol Phosphates; Leukemia, Myeloid, Ac | 1988 |
Phorbol ester stimulation of sphingomyelin synthesis in human leukemic HL60 cells.
Topics: Bryostatins; Cell Line; Choline; Diterpenes; Enzyme Activation; Humans; Lactones; Leukemia, Myeloid, | 1988 |