Page last updated: 2024-10-16

choline and Ischemia

choline has been researched along with Ischemia in 15 studies

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Choline is an essential nutrient with many roles in brain development and function."5.72Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats. ( Adeyemo, T; Banerjee, A; Bumgardner, JG; Jaiyesimi, A; Lohr, C; McKenna, MC; Waddell, J, 2022)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."5.29Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"Brain ischemia was produced in gerbils (Meriones unguiculatus) by the bilateral ligation of the carotid arteries."5.26Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil. ( de Medio, GE; Dorman, RV; Horrocks, LA; Piccinin, GL; Porcellati, G; Trovarelli, G, 1981)
" Interstitial fluid was obtained during tourniquet-induced ischemia and reperfusion and was analyzed for glucose, lactate, choline, and purines by high-performance liquid chromatography."5.09Tourniquet-induced changes of energy metabolism in human skeletal muscle monitored by microdialysis. ( Dogan, G; Fernandez, FF; Jandewerth, O; Klein, J; Koch, T; Korth, U; Merkel, G; van Ackern, K; Weichel, O, 2000)
"The M(3) subtype of muscarinic acetylcholine receptors (M(3)-mAChR) plays a protective role in myocardial ischemia and microRNAs (miRNAs) participate in many cardiac pathophysiological processes, including ischemia-induced cardiac injury."3.78M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p. ( Du, Z; Fan, K; Fan, Y; Guo, F; Guo, Y; Hou, Y; Huo, R; Liu, Y; Pan, Z; Qi, H; Wang, N; Wang, S; Xie, J; Zhang, Y; Zhao, H, 2012)
" We investigated the effect of warm ischemia and reperfusion on sinusoidal microcirculation in rats with fatty livers from a choline-deficient diet."3.69Sinusoidal flow block after warm ischemia in rats with diet-induced fatty liver. ( Hakamada, K; Konn, M; Sasaki, M; Takahashi, K; Umehara, Y, 1997)
"Choline is an essential nutrient with many roles in brain development and function."1.72Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats. ( Adeyemo, T; Banerjee, A; Bumgardner, JG; Jaiyesimi, A; Lohr, C; McKenna, MC; Waddell, J, 2022)
"Choline treatment attenuated I/R-induced vascular dysfunction, blocked elevations in the levels of reactive oxygen species (ROS) and decreased the up-regulated expression of oxidised CaMKII and phosphorylated CaMKII."1.42Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway. ( Bi, XY; He, X; Lu, XZ; Xu, M; Yu, XJ; Zang, WJ; Zhao, M; Zhao, ZH, 2015)
"Choline was detected by liquid chromatography-tandem mass spectrometry."1.39Serial plasma choline measurements after cardiac arrest in patients undergoing mild therapeutic hypothermia: a prospective observational pilot trial. ( Danne, O; Hasper, D; Leithner, C; Schroeder, T; Storm, C; Ueland, PM, 2013)
"In contrast, cardiac arrest induced a rapid but variable decrease of interstitial glucose levels in all monitored organs; this decrease was followed by an increase over baseline during reperfusion."1.32Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis. ( Bertsch, T; Denz, C; Ellinger, K; Henn, C; Janke, C; Klein, J; Korth, U; Krieter, H, 2003)
"It was concluded that in brain metastases of mammary carcinoma Lact represents a product of ischemia preceding/during tissue decay resulting in central necrosis, rather than tumor specific metabolism resulting in increased glycolysis."1.29Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma. ( Oudkerk, M; Sijens, PE; van Dijk, P, 1994)
"Brain ischemia was produced in gerbils (Meriones unguiculatus) by the bilateral ligation of the carotid arteries."1.26Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil. ( de Medio, GE; Dorman, RV; Horrocks, LA; Piccinin, GL; Porcellati, G; Trovarelli, G, 1981)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's3 (20.00)18.2507
2000's2 (13.33)29.6817
2010's3 (20.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Adeyemo, T3
Jaiyesimi, A3
Bumgardner, JG3
Lohr, C3
Banerjee, A3
McKenna, MC3
Waddell, J3
Storm, C1
Danne, O1
Ueland, PM1
Leithner, C1
Hasper, D1
Schroeder, T1
Lu, XZ1
Bi, XY1
He, X1
Zhao, M1
Xu, M1
Yu, XJ1
Zhao, ZH1
Zang, WJ1
Pan, Z1
Guo, Y1
Qi, H1
Fan, K1
Wang, S1
Zhao, H1
Fan, Y1
Xie, J1
Guo, F1
Hou, Y1
Wang, N1
Huo, R1
Zhang, Y1
Liu, Y1
Du, Z1
Korth, U2
Krieter, H1
Denz, C1
Janke, C1
Ellinger, K1
Bertsch, T1
Henn, C1
Klein, J2
Paddock, JK2
Lada, W1
Lowenstein, LM3
Trovarelli, G1
de Medio, GE1
Dorman, RV1
Piccinin, GL1
Horrocks, LA1
Porcellati, G1
Canino, V1
Segre, D1
Sijens, PE1
van Dijk, P1
Oudkerk, M1
Neal, MJ1
Cunningham, JR1
Hutson, PH1
Hogg, J1
Hakamada, K1
Sasaki, M1
Takahashi, K1
Umehara, Y1
Konn, M1
Merkel, G1
Fernandez, FF1
Jandewerth, O1
Dogan, G1
Koch, T1
van Ackern, K1
Weichel, O1
Siegel, MB1
Levinsky, NG1
Altura, BM1
Hersey, SG1
Hyman, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Digestive ENdoscopy afTeR Out-of-hospitAl Cardiac arresT[NCT02349074]221 participants (Actual)Interventional2014-11-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for choline and Ischemia

ArticleYear
Tourniquet-induced changes of energy metabolism in human skeletal muscle monitored by microdialysis.
    Anesthesiology, 2000, Volume: 93, Issue:6

    Topics: Adult; Biomarkers; Choline; Energy Metabolism; Female; Glucose; Humans; Hypoxanthine; Ischemia; Lact

2000

Other Studies

14 other studies available for choline and Ischemia

ArticleYear
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Choline Improves Neonatal Hypoxia-Ischemia Induced Changes in Male but Not Female Rats.
    International journal of molecular sciences, 2022, Nov-12, Volume: 23, Issue:22

    Topics: Animals; Animals, Newborn; Choline; Female; Hypoxia-Ischemia, Brain; Ischemia; Male; Rats

2022
Serial plasma choline measurements after cardiac arrest in patients undergoing mild therapeutic hypothermia: a prospective observational pilot trial.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Biomarkers; Choline; Germany; Heart Arrest; Humans; Hyperthermia, Induced; Ischemia; Pilot Projects;

2013
Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway.
    British journal of pharmacology, 2015, Volume: 172, Issue:23

    Topics: Administration, Intravenous; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Choline; C

2015
M3 subtype of muscarinic acetylcholine receptor promotes cardioprotection via the suppression of miR-376b-5p.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Animals; Calcium; Cell Line; Choline; Down-Regulation; Gene Expression Regulation; Ischemia; Male; M

2012
Intestinal ischaemia during cardiac arrest and resuscitation: comparative analysis of extracellular metabolites by microdialysis.
    Resuscitation, 2003, Volume: 58, Issue:2

    Topics: Animals; Brain; Cardiopulmonary Resuscitation; Choline; Extracellular Space; Glucose; Glutamic Acid;

2003
Regeneration of the renal brush border after renal ischemia in rats.
    The American journal of physiology, 1981, Volume: 241, Issue:1

    Topics: Alkaline Phosphatase; alpha-Glucosidases; Animals; Cell Membrane; Choline; gamma-Glutamyltransferase

1981
Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil.
    Neurochemical research, 1981, Volume: 6, Issue:8

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Carotid Arteries; Choline; Cytidine Diphosphate

1981
[Protective effect of citicoline on renal ischemia].
    Minerva chirurgica, 1980, Mar-31, Volume: 35, Issue:6

    Topics: Animals; Choline; Cytidine Diphosphate Choline; Dogs; Ischemia; Kidney Diseases; Rabbits; Renal Arte

1980
Brush border membrane injury and regeneration following renal ischaemia.
    The International journal of biochemistry, 1980, Volume: 12, Issue:1-2

    Topics: Animals; Cell Membrane; Choline; Ischemia; Kidney; Kinetics; Leucine; Male; Microvilli; Phospholipid

1980
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:5

    Topics: Adult; Aspartic Acid; Brain Neoplasms; Breast Neoplasms; Carcinoma; Choline; Contrast Media; Creatin

1994
Effects of ischaemia on neurotransmitter release from the isolated retina.
    Journal of neurochemistry, 1994, Volume: 62, Issue:3

    Topics: Acetylcholine; Amino Acids; Animals; Calcium; Choline; Dopamine; Hypoglycemia; Hypoxia; In Vitro Tec

1994
Sinusoidal flow block after warm ischemia in rats with diet-induced fatty liver.
    The Journal of surgical research, 1997, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antithrombin III; Choline; Diet; Fatty Liver; Fibrinogen; Hot Tempe

1997
Choline uptake into renal phospholipids following renal ischemia in rats.
    Circulation research, 1979, Volume: 44, Issue:1

    Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Body Water; Carbon Radioisotopes; Chol

1979
Influence of choline on the reticuloendothelial system and on survival after experimental shock.
    Journal of the Reticuloendothelial Society, 1966, Volume: 3, Issue:1

    Topics: Animals; Choline; Female; Ischemia; Mononuclear Phagocyte System; Organ Size; Phagocytosis; Rats; Sh

1966