choline has been researched along with Intellectual Disability in 13 studies
Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We observed mild cerebral and cerebellar atrophy and infarct at bilateral posterior putamen and insular cortex localization on conventional images and elevated choline/creatine ratios and abnormal peak at 3." | 7.74 | Neuroimaging findings in hyperargininemia. ( Akinci, A; Alkan, A; Firat, AK; Güngör, S; Tabel, Y, 2008) |
| " We observed mild cerebral and cerebellar atrophy and infarct at bilateral posterior putamen and insular cortex localization on conventional images and elevated choline/creatine ratios and abnormal peak at 3." | 3.74 | Neuroimaging findings in hyperargininemia. ( Akinci, A; Alkan, A; Firat, AK; Güngör, S; Tabel, Y, 2008) |
| " Here, the developmental and protective effects of SNV were investigated in vivo using two models of developmental retardation, hypoxia and cholinergic blockade." | 3.70 | Protection against developmental deficiencies by a lipophilic VIP analogue. ( Bachar, M; Bardea, A; Davidson, A; Fridkin, M; Gozes, I; Rubinraut, S, 1998) |
| "They presented with congenital microcephaly, severe psychomotor retardation and intractable seizures." | 1.31 | Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency. ( de Koning, TJ; Jaeken, J; Pineda, M; Poll-The, BT; van der Knaap, MS; Van Maldergem, L, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alkan, A | 2 |
| Kutlu, R | 1 |
| Aslan, M | 1 |
| Sigirci, A | 1 |
| Orkan, I | 1 |
| Yakinci, C | 1 |
| Güngör, S | 1 |
| Akinci, A | 1 |
| Firat, AK | 1 |
| Tabel, Y | 1 |
| Martin-Du Pan, RC | 1 |
| Wurtman, RJ | 1 |
| Lejeune, J | 1 |
| Hashimoto, T | 2 |
| Tayama, M | 2 |
| Miyazaki, M | 2 |
| Yoneda, Y | 2 |
| Yoshimoto, T | 2 |
| Harada, M | 2 |
| Miyoshi, H | 2 |
| Tanouchi, M | 2 |
| Kuroda, Y | 2 |
| Gozes, I | 1 |
| Bachar, M | 1 |
| Bardea, A | 1 |
| Davidson, A | 1 |
| Rubinraut, S | 1 |
| Fridkin, M | 1 |
| Pouwels, PJ | 1 |
| Brockmann, K | 1 |
| Kruse, B | 1 |
| Wilken, B | 1 |
| Wick, M | 1 |
| Hanefeld, F | 1 |
| Frahm, J | 1 |
| Critchley, HD | 1 |
| Simmons, A | 1 |
| Daly, EM | 1 |
| Russell, A | 1 |
| van Amelsvoort, T | 1 |
| Robertson, DM | 1 |
| Glover, A | 1 |
| Murphy, DG | 1 |
| de Koning, TJ | 1 |
| Jaeken, J | 1 |
| Pineda, M | 1 |
| Van Maldergem, L | 1 |
| Poll-The, BT | 1 |
| van der Knaap, MS | 1 |
| Tănase, I | 2 |
| Perry, TL | 1 |
| Hansen, S | 1 |
| Love, DL | 1 |
| Crawford, LE | 1 |
| Tischler, B | 1 |
1 review available for choline and Intellectual Disability
| Article | Year |
|---|---|
[The role of nutrition in the synthesis of neurotransmitters and in cerebral functions: clinical implications].
Topics: Alzheimer Disease; Amino Acids; Choline; Choline O-Acetyltransferase; Diabetes Mellitus; Dopa Decarb | 1981 |
12 other studies available for choline and Intellectual Disability
| Article | Year |
|---|---|
Pyridoxine-dependent seizures: magnetic resonance spectroscopy findings.
Topics: Aspartic Acid; Brain Damage, Chronic; Child; Choline; Consanguinity; Creatine; Diagnosis, Differenti | 2004 |
Neuroimaging findings in hyperargininemia.
Topics: Arginine; Aspartic Acid; Atrophy; Basal Ganglia Cerebrovascular Disease; Brain Diseases; Cerebellum; | 2008 |
20 years later.
Topics: Amino Acids; Choline; Down Syndrome; Glutathione Peroxidase; Glyoxylates; Humans; Intellectual Disab | 1981 |
Reduced N-acetylaspartate in the brain observed on in vivo proton magnetic resonance spectroscopy in patients with mental retardation.
Topics: Adolescent; Aspartic Acid; Brain; Brain Chemistry; Child; Child, Preschool; Choline; Creatine; Femal | 1995 |
Differences in brain metabolites between patients with autism and mental retardation as detected by in vivo localized proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Autistic Disorder; Brain; Child; Child, Preschool; Choline; Creatine; Female; Humans; | 1997 |
Protection against developmental deficiencies by a lipophilic VIP analogue.
Topics: Aging; Animals; Aziridines; Choline; Hypoxia; Intellectual Disability; Male; Maze Learning; Memory; | 1998 |
Regional age dependence of human brain metabolites from infancy to adulthood as detected by quantitative localized proton MRS.
Topics: Adolescent; Age Factors; Aspartic Acid; Basal Ganglia; Brain; Brain Neoplasms; Cerebellum; Child; Ch | 1999 |
Prefrontal and medial temporal correlates of repetitive violence to self and others.
Topics: Adult; Amygdala; Aspartic Acid; Choline; Female; Hippocampus; Humans; Intellectual Disability; Inter | 2000 |
Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency.
Topics: Amino Acids; Carbohydrate Dehydrogenases; Cerebral Cortex; Child; Child, Preschool; Choline; Demyeli | 2000 |
[Aspects of the biochemistry of the urine in mental deficiency in children].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Choline; Humans; Infant; | 1975 |
Treatment of homocystinuria with a low-methionine diet, supplemental cystine, and a methyl donor.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Choline; Cys | 1968 |
[Excretion of amino acids, keto acids, pentoses and choline in cerebral anomalies in children].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Brain; Brain Diseases; Child; Child, Preschool; C | 1972 |