Page last updated: 2024-10-16

choline and Hepatitis

choline has been researched along with Hepatitis in 51 studies

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Fatty liver was induced in rats by placing them on a methionine-choline deficient diet for one month."7.72Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. ( Aeed, H; Avni, Y; Birkenfeld, S; Bruck, R; Matas, Z; Shahmurov, M; Shirin, H, 2003)
" Both acute and chronic liver injury models were used: lipopolysaccharide/adenosine-triphosphate to induce in vivo NLRP3 activation, choline-deficient, L-amino acid-defined high-fat diet, and Western-type diet to induce fibrotic nonalcoholic steatohepatitis (NASH)."4.12Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis. ( Booshehri, LM; Broderick, L; Feldstein, AE; Friess, H; Hartmann, D; Hoffman, HM; Kaufmann, B; Kim, AD; Kui, L; Leszczynska, A; Reca, A; Wree, A, 2022)
"The mechanistic significance of oxidative stress to fibrogenesis in the methionine and choline-deficient (MCD) diet-induced model of steatohepatitis was evaluated by antioxidant intervention, using either vitamin E or L-2-oxothiazolidine-4-carboxylate (OTC), a cysteine precursor that promotes glutathione synthesis."3.75Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. ( Farrell, G; George, J; Hou, JY; Leclercq, I; Pera, N; Phung, N, 2009)
" In the methionine- and choline-deficient diet mouse model of steatohepatitis with CYP2E1 overexpression, insulin-induced IRS-1, IRS-2, and Akt phosphorylation were similarly decreased."3.73Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. ( Czaja, MJ; Rigoli, RM; Schattenberg, JM; Singh, R; Wang, Y, 2005)
"Mdr2 (+/-) and Mdr2 (+/+) mice were treated with an MCD or control diet for up to 30 days, and the severity of steatohepatitis, PEMT activity and hepatic S-adenosylmethionine (SAM), and S-adenosylhomocysteine (SAH) levels were measured."3.73Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet. ( Green, RM; Igolnikov, AC, 2006)
"Fatty liver was induced in rats by placing them on a methionine-choline deficient diet for one month."3.72Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. ( Aeed, H; Avni, Y; Birkenfeld, S; Bruck, R; Matas, Z; Shahmurov, M; Shirin, H, 2003)
"plantarum against nonalcoholic steatohepatitis (NASH) and its underlying mechanisms remain unelucidated."1.91Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating L-arginine production. ( Gee, HY; Kim, DY; Park, JY, 2023)
"Non-alcoholic fatty liver disease (NAFLD), represents an unmet medical need that can progress to non-alcoholic steatohepatitis (NASH), which, without intervention, can result in the development of cirrhosis and hepatocellular carcinoma (HCC)."1.72IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models. ( Brightbill, HD; Ding, N; Flanagan, S; Ghilardi, N; Heredia, JE; Jones, C; Leong, L; Martinez, AP; Martzall, A; Nunez, V; Scherl, A; Sorenson, C, 2022)
"Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide."1.43Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis. ( Cappelletti, M; Divanovic, S; Dong, C; Giles, DA; Huppert, SS; Iwakura, Y; Moreno-Fernandez, ME; Shanmukhappa, SK; Stankiewicz, TE, 2016)
"In the MCD dietary model of steatohepatitis, NF-kappaB is activated early and is an important proinflammatory mediator of lesion development, but steatohepatitis occurs independently of TNF synthesis and TNFR-1 activation."1.33NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis. ( Dela Peña, A; Farrell, G; Field, J; George, J; Jones, B; Leclercq, I, 2005)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199038 (74.51)18.7374
1990's0 (0.00)18.2507
2000's8 (15.69)29.6817
2010's1 (1.96)24.3611
2020's4 (7.84)2.80

Authors

AuthorsStudies
Kaufmann, B1
Kui, L1
Reca, A1
Leszczynska, A1
Kim, AD1
Booshehri, LM1
Wree, A1
Friess, H1
Hartmann, D1
Broderick, L1
Hoffman, HM1
Feldstein, AE1
Heredia, JE1
Sorenson, C1
Flanagan, S1
Nunez, V1
Jones, C1
Martzall, A1
Leong, L1
Martinez, AP1
Scherl, A1
Brightbill, HD1
Ghilardi, N1
Ding, N1
Kim, DY1
Park, JY1
Gee, HY1
Lim, T1
Ryu, J1
Lee, K1
Park, SY1
Hwang, KT1
Giles, DA1
Moreno-Fernandez, ME1
Stankiewicz, TE1
Cappelletti, M1
Huppert, SS1
Iwakura, Y1
Dong, C1
Shanmukhappa, SK1
Divanovic, S1
Phung, N1
Pera, N1
Farrell, G2
Leclercq, I2
Hou, JY1
George, J2
STAHL, I1
HILGENBERG, M1
SECKFORT, H1
MULLER, G1
RUEBNER, B1
BRAMHALL, JL1
BERRY, GR1
NOVOZHILOVA-KOSULINA, ON1
BEZKOROVAINAIA, ZG1
EPIFANOVA, EN1
SCHREIER, K1
WILDHIRT, E2
KNAUFF, HG1
GEORGII, A1
MATZEN, K1
TOLSTOVA, II1
RUDENSKAIA, IN2
MARCHESI, E1
PADULA, F1
PETZOLD, H2
LIEBOLD, G1
ITO, F1
YAMAMURA, Y1
HAYANO, K1
LOEPER, J1
DUKA, TV1
SUEYOSHI, Y1
IMAI, Y1
QUINN, PS1
HIGGINSON, J1
KIPPING, H1
CAYER, D2
CORNATZER, WE2
KLEIN, K1
BUHLER, F1
DONHARDT, A1
GABUZDA, GJ1
ECKHARDT, RD1
DAVIDSON, CS1
CZECH, W1
GORS, H1
KIRNBERGER, EJ1
Schattenberg, JM1
Wang, Y1
Singh, R1
Rigoli, RM1
Czaja, MJ1
Dela Peña, A2
Field, J1
Jones, B1
Igolnikov, AC1
Green, RM1
Leclercq, IA1
Williams, J1
Farrell, GC1
Avni, Y1
Shirin, H1
Aeed, H1
Matas, Z1
Shahmurov, M1
Birkenfeld, S1
Bruck, R1
Romestaing, C1
Piquet, MA1
Letexier, D1
Rey, B1
Mourier, A1
Servais, S1
Belouze, M1
Rouleau, V1
Dautresme, M1
Ollivier, I1
Favier, R1
Rigoulet, M1
Duchamp, C1
Sibille, B1
Wortham, M1
He, L1
Gyamfi, M1
Copple, BL1
Wan, YJ1
Menninger, U1
Menninger, W1
Ortlieb, R1
Schneider-Reinkens, A1
Lieber, CS1
Rubin, E1
Szabb, L1
Knick, B1
Ottenjann, R1
Gruner, J1
Kanzler, G1
Phlippen, R1
Schumacher, K1
Gross, R1
Eder, M1
Rocca, F1
Galán Navarro, JL1

Reviews

1 review available for choline and Hepatitis

ArticleYear
Alcoholic fatty liver.
    The New England journal of medicine, 1969, Mar-27, Volume: 280, Issue:13

    Topics: Adult; Alcoholism; Animals; Child; Choline; Diet; Dietary Fats; Dietary Proteins; Drug Synergism; Et

1969

Trials

1 trial available for choline and Hepatitis

ArticleYear
[Comparative studies on conventional and immunosuppressive therapy of chronic hepatitis using chlorambucil].
    Klinische Wochenschrift, 1969, May-15, Volume: 47, Issue:10

    Topics: Adult; Aged; Autoantibodies; Biopsy; Blood Cell Count; Chlorambucil; Choline; Chronic Disease; Diet

1969

Other Studies

49 other studies available for choline and Hepatitis

ArticleYear
Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis.
    Cellular and molecular gastroenterology and hepatology, 2022, Volume: 14, Issue:4

    Topics: Adenosine; Amino Acids; Animals; Caspases; Choline; Hepatitis; Humans; Inflammasomes; Inflammation;

2022
IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models.
    PloS one, 2022, Volume: 17, Issue:9

    Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Choline; Disease Models, Animal; Hepatitis; Inflamm

2022
Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating L-arginine production.
    Experimental & molecular medicine, 2023, Volume: 55, Issue:11

    Topics: Animals; Choline; Diet, High-Fat; Disease Models, Animal; Hepatitis; Humans; Inflammation; Lactobaci

2023
Protective Effects of Black Raspberry (
    Nutrients, 2020, Aug-14, Volume: 12, Issue:8

    Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating

2020
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Choline; Diet; Disease Models, Animal; Hepatitis; Interleukin-17; Macrophages; Male; Methio

2016
Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis.
    International journal of molecular medicine, 2009, Volume: 24, Issue:2

    Topics: Animals; Antioxidants; Choline; Cytokines; Diet; Gene Expression; Glutathione; Hepatic Stellate Cell

2009
[Critical comments on therapy of hepatitis with lipotropic substances].
    Arztliche Wochenschrift, 1952, Oct-24, Volume: 7, Issue:43

    Topics: Choline; Hepatitis; Hepatitis A; Humans; Lipotropic Agents; Methionine

1952
[Metabolic studies in intravenous choline therapy. VIII. The behavior of the blood sugar of healthy and hepatic patients after intravenous methionine administration].
    Klinische Wochenschrift, 1954, May-01, Volume: 32, Issue:17-18

    Topics: Blood Glucose; Choline; Hepatitis; Hepatitis A; Humans; Infusions, Intravenous; Methionine

1954
[Hepatitis and diabetes, a problem in medical practice].
    Therapie der Gegenwart, 1956, Volume: 95, Issue:4

    Topics: Choline; Diabetes Complications; Diabetes Mellitus; Hepatitis; Hepatitis A; Humans; Methionine

1956
Experimental virus hepatitis in choline-deficient mice with fatty livers.
    A.M.A. archives of pathology, 1958, Volume: 66, Issue:2

    Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Hepatitis; Hepatitis A; Mice

1958
[The influence of choline on the carbohydrate metabolism of the liver].
    Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50

    Topics: Carbohydrate Metabolism; Carbohydrates; Choline; Hepatitis; Hepatitis A; Humans; Liver

1958
[The lipotropic action of vitamin B12 and choline].
    Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50

    Topics: Cholesterol; Choline; Communicable Diseases; Corrinoids; Hepatitis; Hepatitis A; Humans; Lipids; Lip

1958
[The influence of vitamin B12 and choline on the pathomorphological changes in the liver in experimental hepatitis].
    Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50

    Topics: Choline; Corrinoids; Hepatitis; Hepatitis A; Vitamin B 12

1958
[Epidemic hepatitis in childhood. Experiences with 850 cases].
    Deutsche medizinische Wochenschrift (1946), 1963, May-17, Volume: 88

    Topics: Choline; Communicable Diseases; Epidemics; gamma-Globulins; Hepatitis; Hepatitis A; Humans; Methioni

1963
[The treatment of acute viral hepatitis with orotic acid choline].
    Therapeutische Umschau. Revue therapeutique, 1962, Volume: 19

    Topics: Choline; Fructose; Hepatitis; Hepatitis A; Humans; Orotic Acid; Viral Vaccines

1962
[THE EFFECT OF CHOLINE PHOSPHOLIPIDS ON THE SPECTRUM OF FREE PLASMA AMINO ACIDS IN TOXIC LIVER DAMAGE].
    Klinische Wochenschrift, 1963, Sep-15, Volume: 41

    Topics: Amino Acids; Blood; Chemical and Drug Induced Liver Injury; Choline; Glycine max; Hepatitis; Linolei

1963
[EFFECT OF CHOLINE CHLORIDE ON SOME INDICES OF FAT METABOLISM IN BOTKIN'S DISEASE IN CHILDREN].
    Voprosy okhrany materinstva i detstva, 1963, Volume: 8

    Topics: Adolescent; Bile Pigments; Bilirubin; Child; Cholesterol; Choline; Clinical Enzyme Tests; Communicab

1963
[THE ASSOCIATION OF SORBITOL, GLUTAMIC ACID AND CHOLINE HYPOSULFITE IN THE THERAPY OF HEPATIC DISEASES AND MINOR HEPATIC INSUFFICIENCY].
    Gazzetta medica italiana, 1963, Volume: 122

    Topics: Adolescent; Biliary Dyskinesia; Child; Cholangitis; Cholecystitis; Cholelithiasis; Choline; Dithioni

1963
[ALKALINE PHOSPHATASE AND MUCOPOLYSACCHARIDES IN GRANULOCYTES UNDER THE INFLUENCE OF LEVULOSE AND CHOLINE INFUSIONS].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1963, Volume: 23

    Topics: Acetylcholine; Alkaline Phosphatase; Choline; Fructose; Glycosaminoglycans; Granulocytes; Hepatitis;

1963
THE FATTY LIVER INDUCTION OF ALPHA-ETHYLTHIOISONICOTINAMIDE (ETHIONIAMIDE, 1314TH).
    Journal of biochemistry, 1964, Volume: 55

    Topics: Chemical and Drug Induced Liver Injury; Choline; Ethionamide; Fatty Liver; Hepatitis; Nucleosides; P

1964
[THE PROBLEM OF PARENCHYMATOUS REPAIR OF THE LIVER].
    Le Progres medical, 1964, Apr-10, Volume: 92

    Topics: Adenosine Triphosphate; Chemical and Drug Induced Liver Injury; Choline; Hepatectomy; Hepatitis; Liv

1964
[EFFECT OF CHOLINE CHLORIDE ON SOME FUNCTIONS OF THE LIVER IN BOTKIN'S DISEASE].
    Sovetskaia meditsina, 1964, Volume: 27

    Topics: Chlorides; Choline; Communicable Diseases; Drug Therapy; Hepatitis; Hepatitis A; Humans; Liver Funct

1964
INFLUENCE OF LACTOSE ON AMOUNT OF LIVER-FAT IN FATTY LIVERS.
    The Keio journal of medicine, 1964, Volume: 13

    Topics: Carbohydrate Metabolism; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cho

1964
REVERSIBLE AND IRREVERSIBLE CHANGES IN EXPERIMENTAL CIRRHOSIS.
    The American journal of pathology, 1965, Volume: 47

    Topics: Amides; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Choline Def

1965
[Comparative evaluation of the effectiveness of some methods of treatment of Botkin's disease in children].
    Sovetskaia meditsina, 1962, Volume: 26

    Topics: Child; Choline; Corrinoids; Glucose; Hepatitis; Hepatitis A; Humans; Vitamin B 12; Vitamin B 6; Vita

1962
[Choline therapy in infectious hepatitis].
    Deutsche medizinische Wochenschrift (1946), 1951, Feb-16, Volume: 76, Issue:7

    Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Humans; Viral Vaccines

1951
The effects of lipotropic factors on the phospholipide turnover in patients with infectious hepatitis.
    Gastroenterology, 1951, Volume: 18, Issue:1

    Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Lipotropic Agents; Methionine; Phospholipids

1951
[Consideration on hepatitis therapy].
    Arztliche Wochenschrift, 1951, Jul-13, Volume: 6, Issue:28

    Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Methionine; Viral Vaccines

1951
[On choline therapy].
    Therapie der Gegenwart, 1952, Volume: 91, Issue:4

    Topics: Choline; Hepatitis; Hepatitis A; Humans; Liver Cirrhosis; Viral Vaccines

1952
Phospholipid synthesis in patients with cirrhosis and infectious hepatitis; the effects of choline and methionine as measured by radioactive phosphorus.
    Southern medical journal, 1950, Volume: 43, Issue:3

    Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Liver; Liver Cirrhosis; Methionine; Phosphor

1950
Effect of choline and methionine, testosterone propionate, and dietary protein on nitrogen balance in patients with liver disease.
    The Journal of clinical investigation, 1950, Volume: 29, Issue:5

    Topics: Choline; Dietary Proteins; Hepatitis; Hepatitis A; Liver; Liver Diseases; Methionine; Nitrogen; Prot

1950
[Lipotropic substances in the treatment of liver disease].
    Medizinische Klinik, 1950, Jun-16, Volume: 45, Issue:24

    Topics: Choline; Hepatitis; Hepatitis A; Lipotropic Agents; Liver; Liver Diseases; Methionine

1950
[Experiences with hepsan, a new methionine-choline preparation, in treatment of acute epidemic hepatitis].
    Munchener medizinische Wochenschrift (1950), 1950, Jul-07, Volume: 92, Issue:13-14

    Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Humans; Methionine

1950
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.
    The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11

    Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Cell Line; Choline; Cytochrome P-450 C

2005
NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis.
    Gastroenterology, 2005, Volume: 129, Issue:5

    Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Female; Hepatitis;

2005
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet.
    Journal of hepatology, 2006, Volume: 44, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4;

2006
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.
    Journal of hepatology, 2007, Volume: 46, Issue:2

    Topics: Animals; Chemokine CCL2; Chemokine CCL4; Choline; Choline Deficiency; Cyclooxygenase 2; Diet; Diseas

2007
Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis.
    Journal of medicine, 2003, Volume: 34, Issue:1-6

    Topics: Animals; Choline; Cytochrome P-450 CYP2E1; Fatty Liver; Hepatitis; Liver; Male; Methionine; NF-kappa

2003
Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet.
    American journal of physiology. Endocrinology and metabolism, 2008, Volume: 294, Issue:1

    Topics: Adaptation, Physiological; Animal Feed; Animals; Choline; Choline Deficiency; Energy Metabolism; Fat

2008
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:10

    Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated

2008
[Clinical experience report on Hepavis].
    Die Medizinische Welt, 1980, Oct-17, Volume: 31, Issue:42

    Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Choline; Dehydrocholic Acid; Drug Co

1980
[Drug therapy of hepatitis in childhood].
    Monatsschrift fur Kinderheilkunde, 1975, Volume: 123, Issue:8

    Topics: Adrenal Cortex Hormones; Androgens; Child; Choline; gamma-Globulins; Hepatitis; Humans; Liver; Methi

1975
[Therapeutic results with Hepsan in selected forms of hepatitis].
    MMW, Munchener medizinische Wochenschrift, 1977, Jun-24, Volume: 119, Issue:25

    Topics: Acute Disease; Choline; Chronic Disease; Drug Combinations; Female; Hepatitis; Humans; Lipid Metabol

1977
[Liver tissue enzymes in rats with galactosamine hepatitis during simultaneous administration of choline-orotate].
    Ceskoslovenska gynekologie, 1973, Volume: 27, Issue:5

    Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Ch

1973
[Therapeutic progress in chronic liver diseases].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1968, Volume: 28, Issue:2

    Topics: Choline; Chronic Disease; Folic Acid; Hepatitis; Humans; Liver Cirrhosis; Orotic Acid; Thioctic Acid

1968
[Clinical treatment of acute and chronic liver diseases].
    Zeitschrift fur Allgemeinmedizin, 1972, Feb-10, Volume: 48, Issue:4

    Topics: Acute Disease; Choline; Chronic Disease; Fatty Liver; Hepatitis; Humans; Liver Diseases; Male; Methi

1972
[Dietetic therapy of liver diseases].
    Minerva medica, 1972, Jun-27, Volume: 63, Issue:49

    Topics: Choline; Chronic Disease; Diet Therapy; Dietary Proteins; Fatty Acids; Fatty Liver; Hepatic Encephal

1972
[Clinical experience with a new hepatoprotector].
    La Clinica terapeutica, 1969, Jun-15, Volume: 49, Issue:5

    Topics: Adolescent; Adult; Bilirubin; Choline; Gastrointestinal Diseases; Hepatitis; Homocysteine; Humans; L

1969
[Evolution of chronic diffuse liver diseases treated by essential choline phospholipid therapy. Clinical and analytical control through exploration with radioactive isotopes].
    Revista espanola de las enfermedades del aparato digestivo, 1967, Volume: 26, Issue:4

    Topics: Adult; Choline; Female; Gold Isotopes; Hepatitis; Humans; Iodine Radioisotopes; Liver Cirrhosis; Liv

1967