Page last updated: 2024-10-16

choline and Hepatitis

choline has been researched along with Hepatitis in 51 studies

Hepatitis: INFLAMMATION of the LIVER.

Research Excerpts

Excerpt	Relevance	Reference
"Fatty liver was induced in rats by placing them on a methionine-choline deficient diet for one month."	7.72	Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. ( Aeed, H; Avni, Y; Birkenfeld, S; Bruck, R; Matas, Z; Shahmurov, M; Shirin, H, 2003)
" Both acute and chronic liver injury models were used: lipopolysaccharide/adenosine-triphosphate to induce in vivo NLRP3 activation, choline-deficient, L-amino acid-defined high-fat diet, and Western-type diet to induce fibrotic nonalcoholic steatohepatitis (NASH)."	4.12	Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis. ( Booshehri, LM; Broderick, L; Feldstein, AE; Friess, H; Hartmann, D; Hoffman, HM; Kaufmann, B; Kim, AD; Kui, L; Leszczynska, A; Reca, A; Wree, A, 2022)
"The mechanistic significance of oxidative stress to fibrogenesis in the methionine and choline-deficient (MCD) diet-induced model of steatohepatitis was evaluated by antioxidant intervention, using either vitamin E or L-2-oxothiazolidine-4-carboxylate (OTC), a cysteine precursor that promotes glutathione synthesis."	3.75	Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. ( Farrell, G; George, J; Hou, JY; Leclercq, I; Pera, N; Phung, N, 2009)
" In the methionine- and choline-deficient diet mouse model of steatohepatitis with CYP2E1 overexpression, insulin-induced IRS-1, IRS-2, and Akt phosphorylation were similarly decreased."	3.73	Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. ( Czaja, MJ; Rigoli, RM; Schattenberg, JM; Singh, R; Wang, Y, 2005)
"Mdr2 (+/-) and Mdr2 (+/+) mice were treated with an MCD or control diet for up to 30 days, and the severity of steatohepatitis, PEMT activity and hepatic S-adenosylmethionine (SAM), and S-adenosylhomocysteine (SAH) levels were measured."	3.73	Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet. ( Green, RM; Igolnikov, AC, 2006)
"Fatty liver was induced in rats by placing them on a methionine-choline deficient diet for one month."	3.72	Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. ( Aeed, H; Avni, Y; Birkenfeld, S; Bruck, R; Matas, Z; Shahmurov, M; Shirin, H, 2003)
"plantarum against nonalcoholic steatohepatitis (NASH) and its underlying mechanisms remain unelucidated."	1.91	Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating L-arginine production. ( Gee, HY; Kim, DY; Park, JY, 2023)
"Non-alcoholic fatty liver disease (NAFLD), represents an unmet medical need that can progress to non-alcoholic steatohepatitis (NASH), which, without intervention, can result in the development of cirrhosis and hepatocellular carcinoma (HCC)."	1.72	IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models. ( Brightbill, HD; Ding, N; Flanagan, S; Ghilardi, N; Heredia, JE; Jones, C; Leong, L; Martinez, AP; Martzall, A; Nunez, V; Scherl, A; Sorenson, C, 2022)
"Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide."	1.43	Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis. ( Cappelletti, M; Divanovic, S; Dong, C; Giles, DA; Huppert, SS; Iwakura, Y; Moreno-Fernandez, ME; Shanmukhappa, SK; Stankiewicz, TE, 2016)
"In the MCD dietary model of steatohepatitis, NF-kappaB is activated early and is an important proinflammatory mediator of lesion development, but steatohepatitis occurs independently of TNF synthesis and TNFR-1 activation."	1.33	NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis. ( Dela Peña, A; Farrell, G; Field, J; George, J; Jones, B; Leclercq, I, 2005)

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (74.51)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (15.69)	29.6817
2010's	1 (1.96)	24.3611
2020's	4 (7.84)	2.80

Authors

Authors	Studies
Kaufmann, B	1
Kui, L	1
Reca, A	1
Leszczynska, A	1
Kim, AD	1
Booshehri, LM	1
Wree, A	1
Friess, H	1
Hartmann, D	1
Broderick, L	1
Hoffman, HM	1
Feldstein, AE	1
Heredia, JE	1
Sorenson, C	1
Flanagan, S	1
Nunez, V	1
Jones, C	1
Martzall, A	1
Leong, L	1
Martinez, AP	1
Scherl, A	1
Brightbill, HD	1
Ghilardi, N	1
Ding, N	1
Kim, DY	1
Park, JY	1
Gee, HY	1
Lim, T	1
Ryu, J	1
Lee, K	1
Park, SY	1
Hwang, KT	1
Giles, DA	1
Moreno-Fernandez, ME	1
Stankiewicz, TE	1
Cappelletti, M	1
Huppert, SS	1
Iwakura, Y	1
Dong, C	1
Shanmukhappa, SK	1
Divanovic, S	1
Phung, N	1
Pera, N	1
Farrell, G	2
Leclercq, I	2
Hou, JY	1
George, J	2
STAHL, I	1
HILGENBERG, M	1
SECKFORT, H	1
MULLER, G	1
RUEBNER, B	1
BRAMHALL, JL	1
BERRY, GR	1
NOVOZHILOVA-KOSULINA, ON	1
BEZKOROVAINAIA, ZG	1
EPIFANOVA, EN	1
SCHREIER, K	1
WILDHIRT, E	2
KNAUFF, HG	1
GEORGII, A	1
MATZEN, K	1
TOLSTOVA, II	1
RUDENSKAIA, IN	2
MARCHESI, E	1
PADULA, F	1
PETZOLD, H	2
LIEBOLD, G	1
ITO, F	1
YAMAMURA, Y	1
HAYANO, K	1
LOEPER, J	1
DUKA, TV	1
SUEYOSHI, Y	1
IMAI, Y	1
QUINN, PS	1
HIGGINSON, J	1
KIPPING, H	1
CAYER, D	2
CORNATZER, WE	2
KLEIN, K	1
BUHLER, F	1
DONHARDT, A	1
GABUZDA, GJ	1
ECKHARDT, RD	1
DAVIDSON, CS	1
CZECH, W	1
GORS, H	1
KIRNBERGER, EJ	1
Schattenberg, JM	1
Wang, Y	1
Singh, R	1
Rigoli, RM	1
Czaja, MJ	1
Dela Peña, A	2
Field, J	1
Jones, B	1
Igolnikov, AC	1
Green, RM	1
Leclercq, IA	1
Williams, J	1
Farrell, GC	1
Avni, Y	1
Shirin, H	1
Aeed, H	1
Matas, Z	1
Shahmurov, M	1
Birkenfeld, S	1
Bruck, R	1
Romestaing, C	1
Piquet, MA	1
Letexier, D	1
Rey, B	1
Mourier, A	1
Servais, S	1
Belouze, M	1
Rouleau, V	1
Dautresme, M	1
Ollivier, I	1
Favier, R	1
Rigoulet, M	1
Duchamp, C	1
Sibille, B	1
Wortham, M	1
He, L	1
Gyamfi, M	1
Copple, BL	1
Wan, YJ	1
Menninger, U	1
Menninger, W	1
Ortlieb, R	1
Schneider-Reinkens, A	1
Lieber, CS	1
Rubin, E	1
Szabb, L	1
Knick, B	1
Ottenjann, R	1
Gruner, J	1
Kanzler, G	1
Phlippen, R	1
Schumacher, K	1
Gross, R	1
Eder, M	1
Rocca, F	1
Galán Navarro, JL	1

Reviews

1 review available for choline and Hepatitis

Article	Year
Alcoholic fatty liver. The New England journal of medicine, 1969, Mar-27, Volume: 280, Issue:13 Topics: Adult; Alcoholism; Animals; Child; Choline; Diet; Dietary Fats; Dietary Proteins; Drug Synergism; Et	1969

Trials

1 trial available for choline and Hepatitis

Article	Year
[Comparative studies on conventional and immunosuppressive therapy of chronic hepatitis using chlorambucil]. Klinische Wochenschrift, 1969, May-15, Volume: 47, Issue:10 Topics: Adult; Aged; Autoantibodies; Biopsy; Blood Cell Count; Chlorambucil; Choline; Chronic Disease; Diet	1969

Other Studies

49 other studies available for choline and Hepatitis

Article	Year
Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis. Cellular and molecular gastroenterology and hepatology, 2022, Volume: 14, Issue:4 Topics: Adenosine; Amino Acids; Animals; Caspases; Choline; Hepatitis; Humans; Inflammasomes; Inflammation;	2022
IL-23 signaling is not an important driver of liver inflammation and fibrosis in murine non-alcoholic steatohepatitis models. PloS one, 2022, Volume: 17, Issue:9 Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Choline; Disease Models, Animal; Hepatitis; Inflamm	2022
Lactobacillus plantarum ameliorates NASH-related inflammation by upregulating L-arginine production. Experimental & molecular medicine, 2023, Volume: 55, Issue:11 Topics: Animals; Choline; Diet, High-Fat; Disease Models, Animal; Hepatitis; Humans; Inflammation; Lactobaci	2023
Protective Effects of Black Raspberry ( Nutrients, 2020, Aug-14, Volume: 12, Issue:8 Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating	2020
Regulation of Inflammation by IL-17A and IL-17F Modulates Non-Alcoholic Fatty Liver Disease Pathogenesis. PloS one, 2016, Volume: 11, Issue:2 Topics: Animals; Choline; Diet; Disease Models, Animal; Hepatitis; Interleukin-17; Macrophages; Male; Methio	2016
Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis. International journal of molecular medicine, 2009, Volume: 24, Issue:2 Topics: Animals; Antioxidants; Choline; Cytokines; Diet; Gene Expression; Glutathione; Hepatic Stellate Cell	2009
[Critical comments on therapy of hepatitis with lipotropic substances]. Arztliche Wochenschrift, 1952, Oct-24, Volume: 7, Issue:43 Topics: Choline; Hepatitis; Hepatitis A; Humans; Lipotropic Agents; Methionine	1952
[Metabolic studies in intravenous choline therapy. VIII. The behavior of the blood sugar of healthy and hepatic patients after intravenous methionine administration]. Klinische Wochenschrift, 1954, May-01, Volume: 32, Issue:17-18 Topics: Blood Glucose; Choline; Hepatitis; Hepatitis A; Humans; Infusions, Intravenous; Methionine	1954
[Hepatitis and diabetes, a problem in medical practice]. Therapie der Gegenwart, 1956, Volume: 95, Issue:4 Topics: Choline; Diabetes Complications; Diabetes Mellitus; Hepatitis; Hepatitis A; Humans; Methionine	1956
Experimental virus hepatitis in choline-deficient mice with fatty livers. A.M.A. archives of pathology, 1958, Volume: 66, Issue:2 Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Hepatitis; Hepatitis A; Mice	1958
[The influence of choline on the carbohydrate metabolism of the liver]. Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50 Topics: Carbohydrate Metabolism; Carbohydrates; Choline; Hepatitis; Hepatitis A; Humans; Liver	1958
[The lipotropic action of vitamin B12 and choline]. Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50 Topics: Cholesterol; Choline; Communicable Diseases; Corrinoids; Hepatitis; Hepatitis A; Humans; Lipids; Lip	1958
[The influence of vitamin B12 and choline on the pathomorphological changes in the liver in experimental hepatitis]. Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1958, Volume: 50 Topics: Choline; Corrinoids; Hepatitis; Hepatitis A; Vitamin B 12	1958
[Epidemic hepatitis in childhood. Experiences with 850 cases]. Deutsche medizinische Wochenschrift (1946), 1963, May-17, Volume: 88 Topics: Choline; Communicable Diseases; Epidemics; gamma-Globulins; Hepatitis; Hepatitis A; Humans; Methioni	1963
[The treatment of acute viral hepatitis with orotic acid choline]. Therapeutische Umschau. Revue therapeutique, 1962, Volume: 19 Topics: Choline; Fructose; Hepatitis; Hepatitis A; Humans; Orotic Acid; Viral Vaccines	1962
[THE EFFECT OF CHOLINE PHOSPHOLIPIDS ON THE SPECTRUM OF FREE PLASMA AMINO ACIDS IN TOXIC LIVER DAMAGE]. Klinische Wochenschrift, 1963, Sep-15, Volume: 41 Topics: Amino Acids; Blood; Chemical and Drug Induced Liver Injury; Choline; Glycine max; Hepatitis; Linolei	1963
[EFFECT OF CHOLINE CHLORIDE ON SOME INDICES OF FAT METABOLISM IN BOTKIN'S DISEASE IN CHILDREN]. Voprosy okhrany materinstva i detstva, 1963, Volume: 8 Topics: Adolescent; Bile Pigments; Bilirubin; Child; Cholesterol; Choline; Clinical Enzyme Tests; Communicab	1963
[THE ASSOCIATION OF SORBITOL, GLUTAMIC ACID AND CHOLINE HYPOSULFITE IN THE THERAPY OF HEPATIC DISEASES AND MINOR HEPATIC INSUFFICIENCY]. Gazzetta medica italiana, 1963, Volume: 122 Topics: Adolescent; Biliary Dyskinesia; Child; Cholangitis; Cholecystitis; Cholelithiasis; Choline; Dithioni	1963
[ALKALINE PHOSPHATASE AND MUCOPOLYSACCHARIDES IN GRANULOCYTES UNDER THE INFLUENCE OF LEVULOSE AND CHOLINE INFUSIONS]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1963, Volume: 23 Topics: Acetylcholine; Alkaline Phosphatase; Choline; Fructose; Glycosaminoglycans; Granulocytes; Hepatitis;	1963
THE FATTY LIVER INDUCTION OF ALPHA-ETHYLTHIOISONICOTINAMIDE (ETHIONIAMIDE, 1314TH). Journal of biochemistry, 1964, Volume: 55 Topics: Chemical and Drug Induced Liver Injury; Choline; Ethionamide; Fatty Liver; Hepatitis; Nucleosides; P	1964
[THE PROBLEM OF PARENCHYMATOUS REPAIR OF THE LIVER]. Le Progres medical, 1964, Apr-10, Volume: 92 Topics: Adenosine Triphosphate; Chemical and Drug Induced Liver Injury; Choline; Hepatectomy; Hepatitis; Liv	1964
[EFFECT OF CHOLINE CHLORIDE ON SOME FUNCTIONS OF THE LIVER IN BOTKIN'S DISEASE]. Sovetskaia meditsina, 1964, Volume: 27 Topics: Chlorides; Choline; Communicable Diseases; Drug Therapy; Hepatitis; Hepatitis A; Humans; Liver Funct	1964
INFLUENCE OF LACTOSE ON AMOUNT OF LIVER-FAT IN FATTY LIVERS. The Keio journal of medicine, 1964, Volume: 13 Topics: Carbohydrate Metabolism; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cho	1964
REVERSIBLE AND IRREVERSIBLE CHANGES IN EXPERIMENTAL CIRRHOSIS. The American journal of pathology, 1965, Volume: 47 Topics: Amides; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Choline Def	1965
[Comparative evaluation of the effectiveness of some methods of treatment of Botkin's disease in children]. Sovetskaia meditsina, 1962, Volume: 26 Topics: Child; Choline; Corrinoids; Glucose; Hepatitis; Hepatitis A; Humans; Vitamin B 12; Vitamin B 6; Vita	1962
[Choline therapy in infectious hepatitis]. Deutsche medizinische Wochenschrift (1946), 1951, Feb-16, Volume: 76, Issue:7 Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Humans; Viral Vaccines	1951
The effects of lipotropic factors on the phospholipide turnover in patients with infectious hepatitis. Gastroenterology, 1951, Volume: 18, Issue:1 Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Lipotropic Agents; Methionine; Phospholipids	1951
[Consideration on hepatitis therapy]. Arztliche Wochenschrift, 1951, Jul-13, Volume: 6, Issue:28 Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Methionine; Viral Vaccines	1951
[On choline therapy]. Therapie der Gegenwart, 1952, Volume: 91, Issue:4 Topics: Choline; Hepatitis; Hepatitis A; Humans; Liver Cirrhosis; Viral Vaccines	1952
Phospholipid synthesis in patients with cirrhosis and infectious hepatitis; the effects of choline and methionine as measured by radioactive phosphorus. Southern medical journal, 1950, Volume: 43, Issue:3 Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Liver; Liver Cirrhosis; Methionine; Phosphor	1950
Effect of choline and methionine, testosterone propionate, and dietary protein on nitrogen balance in patients with liver disease. The Journal of clinical investigation, 1950, Volume: 29, Issue:5 Topics: Choline; Dietary Proteins; Hepatitis; Hepatitis A; Liver; Liver Diseases; Methionine; Nitrogen; Prot	1950
[Lipotropic substances in the treatment of liver disease]. Medizinische Klinik, 1950, Jun-16, Volume: 45, Issue:24 Topics: Choline; Hepatitis; Hepatitis A; Lipotropic Agents; Liver; Liver Diseases; Methionine	1950
[Experiences with hepsan, a new methionine-choline preparation, in treatment of acute epidemic hepatitis]. Munchener medizinische Wochenschrift (1950), 1950, Jul-07, Volume: 92, Issue:13-14 Topics: Choline; Communicable Diseases; Hepatitis; Hepatitis A; Humans; Methionine	1950
Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. The Journal of biological chemistry, 2005, Mar-18, Volume: 280, Issue:11 Topics: Adenoviridae; Animals; Blotting, Northern; Blotting, Western; Cell Line; Choline; Cytochrome P-450 C	2005
NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis. Gastroenterology, 2005, Volume: 129, Issue:5 Topics: Animals; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver; Female; Hepatitis;	2005
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet. Journal of hepatology, 2006, Volume: 44, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4;	2006
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis. Journal of hepatology, 2007, Volume: 46, Issue:2 Topics: Animals; Chemokine CCL2; Chemokine CCL4; Choline; Choline Deficiency; Cyclooxygenase 2; Diet; Diseas	2007
Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. Journal of medicine, 2003, Volume: 34, Issue:1-6 Topics: Animals; Choline; Cytochrome P-450 CYP2E1; Fatty Liver; Hepatitis; Liver; Male; Methionine; NF-kappa	2003
Mitochondrial adaptations to steatohepatitis induced by a methionine- and choline-deficient diet. American journal of physiology. Endocrinology and metabolism, 2008, Volume: 294, Issue:1 Topics: Adaptation, Physiological; Animal Feed; Animals; Choline; Choline Deficiency; Energy Metabolism; Fat	2008
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Digestive diseases and sciences, 2008, Volume: 53, Issue:10 Topics: Animals; Choline; Disease Models, Animal; Disease Progression; Fatty Liver; Female; Food, Formulated	2008
[Clinical experience report on Hepavis]. Die Medizinische Welt, 1980, Oct-17, Volume: 31, Issue:42 Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Choline; Dehydrocholic Acid; Drug Co	1980
[Drug therapy of hepatitis in childhood]. Monatsschrift fur Kinderheilkunde, 1975, Volume: 123, Issue:8 Topics: Adrenal Cortex Hormones; Androgens; Child; Choline; gamma-Globulins; Hepatitis; Humans; Liver; Methi	1975
[Therapeutic results with Hepsan in selected forms of hepatitis]. MMW, Munchener medizinische Wochenschrift, 1977, Jun-24, Volume: 119, Issue:25 Topics: Acute Disease; Choline; Chronic Disease; Drug Combinations; Female; Hepatitis; Humans; Lipid Metabol	1977
[Liver tissue enzymes in rats with galactosamine hepatitis during simultaneous administration of choline-orotate]. Ceskoslovenska gynekologie, 1973, Volume: 27, Issue:5 Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Chemical and Drug Induced Liver Injury; Ch	1973
[Therapeutic progress in chronic liver diseases]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1968, Volume: 28, Issue:2 Topics: Choline; Chronic Disease; Folic Acid; Hepatitis; Humans; Liver Cirrhosis; Orotic Acid; Thioctic Acid	1968
[Clinical treatment of acute and chronic liver diseases]. Zeitschrift fur Allgemeinmedizin, 1972, Feb-10, Volume: 48, Issue:4 Topics: Acute Disease; Choline; Chronic Disease; Fatty Liver; Hepatitis; Humans; Liver Diseases; Male; Methi	1972
[Dietetic therapy of liver diseases]. Minerva medica, 1972, Jun-27, Volume: 63, Issue:49 Topics: Choline; Chronic Disease; Diet Therapy; Dietary Proteins; Fatty Acids; Fatty Liver; Hepatic Encephal	1972
[Clinical experience with a new hepatoprotector]. La Clinica terapeutica, 1969, Jun-15, Volume: 49, Issue:5 Topics: Adolescent; Adult; Bilirubin; Choline; Gastrointestinal Diseases; Hepatitis; Homocysteine; Humans; L	1969
[Evolution of chronic diffuse liver diseases treated by essential choline phospholipid therapy. Clinical and analytical control through exploration with radioactive isotopes]. Revista espanola de las enfermedades del aparato digestivo, 1967, Volume: 26, Issue:4 Topics: Adult; Choline; Female; Gold Isotopes; Hepatitis; Humans; Iodine Radioisotopes; Liver Cirrhosis; Liv	1967

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