choline has been researched along with Experimental Mammary Neoplasms in 11 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Choline is an essential nutrient that serves as a donor of metabolic methyl groups used during gestation to establish the epigenetic DNA methylation patterns that modulate tissue-specific gene expression." | 1.35 | Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. ( Blusztajn, JK; Davison, JM; Kovacheva, VP; Mellott, TJ; O'Brien, MJ; Rogers, AE; Yang, S, 2009) |
| " After oral application He-PC was well absorbed from the intestine and metabolized in the liver by phospholipases C and D." | 1.28 | Hexadecylphosphocholine, a new ether lipid analogue. Studies on the antineoplastic activity in vitro and in vivo. ( Breiser, A; Damenz, W; Eibl, H; Engel, J; Fleer, EA; Hilgard, P; Kim, DJ; Nagel, G; Unger, C, 1989) |
| " A dose-response relationship was seen after daily oral treatment with complete suppression of tumor growth at doses of 46." | 1.27 | Characterization of the antitumor activity of hexadecylphosphocholine (D 18506). ( Berger, MR; Eibl, H; Engel, J; Hilgard, P; Schumacher, W; Stekar, J; Unger, C; Voegeli, R, 1988) |
| " In rats, the LD50 of HPC was 606 mumol/kg; the maximum tolerable dose over four weeks was 39 mumol/kg." | 1.27 | Alkyl phosphocholines: toxicity and anticancer properties. ( Berger, MR; Eibl, HJ; Garzon, FT; Muschiol, C; Scherf, HR; Schmähl, D; Schuler, B; Unger, C; Zeller, WJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovacheva, VP | 1 |
| Davison, JM | 1 |
| Mellott, TJ | 1 |
| Rogers, AE | 1 |
| Yang, S | 1 |
| O'Brien, MJ | 1 |
| Blusztajn, JK | 1 |
| Amstalden van Hove, ER | 1 |
| Blackwell, TR | 1 |
| Klinkert, I | 1 |
| Eijkel, GB | 1 |
| Heeren, RM | 1 |
| Glunde, K | 1 |
| Reindl, W | 1 |
| Bowen, BP | 1 |
| Balamotis, MA | 1 |
| Green, JE | 1 |
| Northen, TR | 1 |
| Street, JC | 1 |
| Szwergold, BS | 1 |
| Matei, C | 1 |
| Kappler, F | 1 |
| Mahmood, U | 1 |
| Brown, TR | 1 |
| Koutcher, JA | 1 |
| Nielsen, FU | 1 |
| Topp, S | 1 |
| Horsman, MR | 1 |
| Overgaard, J | 1 |
| Stødkilde-Jørgensen, H | 1 |
| Maxwell, RJ | 1 |
| Saito, R | 1 |
| Palomba, L | 1 |
| Rao, KN | 1 |
| Lombardi, B | 1 |
| Unger, C | 3 |
| Damenz, W | 1 |
| Fleer, EA | 1 |
| Kim, DJ | 1 |
| Breiser, A | 1 |
| Hilgard, P | 2 |
| Engel, J | 2 |
| Nagel, G | 1 |
| Eibl, H | 2 |
| Stekar, J | 1 |
| Voegeli, R | 1 |
| Schumacher, W | 1 |
| Berger, MR | 3 |
| Scherf, HR | 2 |
| Schuler, B | 2 |
| Schmähl, D | 2 |
| Muschiol, C | 1 |
| Garzon, FT | 1 |
| Zeller, WJ | 1 |
| Eibl, HJ | 1 |
| Hillyard, LA | 1 |
| Abraham, S | 1 |
11 other studies available for choline and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Carcinogens; Choline; Choline Deficiency; | 2009 |
Multimodal mass spectrometric imaging of small molecules reveals distinct spatio-molecular signatures in differentially metastatic breast tumor models.
Topics: Animals; Breast Neoplasms; Choline; Female; Glycerylphosphorylcholine; Humans; Magnetic Resonance Im | 2010 |
Multivariate analysis of a 3D mass spectral image for examining tissue heterogeneity.
Topics: Adipose Tissue; Animals; Cell Count; Choline; Female; Image Interpretation, Computer-Assisted; Imagi | 2011 |
Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium-choline.
Topics: Adenocarcinoma; Animals; Choline; Female; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experi | 1997 |
Localized in vivo 1H NMR spectroscopy of murine tumours: effect of blood flow reduction.
Topics: Animals; Choline; Hydralazine; Lactic Acid; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Expe | 1999 |
Resistance of female Fischer-344 rats to the hepatonecrogenic and hepatocarcinogenic actions of a choline-devoid diet.
Topics: Animals; Choline; Diet; Female; Liver; Liver Neoplasms, Experimental; Male; Mammary Neoplasms, Exper | 1991 |
Hexadecylphosphocholine, a new ether lipid analogue. Studies on the antineoplastic activity in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Choline; Drug Screening Assays, Antitumor; Female; | 1989 |
Characterization of the antitumor activity of hexadecylphosphocholine (D 18506).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Choline; Cyclophosphamide; Dose-Response Re | 1988 |
Therapeutic activity of ET-18-OCH3 and hexadecylphosphocholine against mammary tumors in BD-VI rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Choline; Dose-Response Relationship, Drug; Fem | 1987 |
Alkyl phosphocholines: toxicity and anticancer properties.
Topics: Animals; Antineoplastic Agents; Carcinoma; Choline; Dose-Response Relationship, Drug; Female; Male; | 1987 |
Membrane proliferation and phosphatidylcholine synthesis in normal, preneoplastic, and neoplastic mammary gland tissues in C3H mice.
Topics: Adenocarcinoma; Animals; Carbon Isotopes; Choline; Cytochrome c Group; DNA; Endoplasmic Reticulum; F | 1972 |