Page last updated: 2024-10-16

choline and Endotoxemia

choline has been researched along with Endotoxemia in 10 studies

Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.

Research Excerpts

ExcerptRelevanceReference
"Decreased ROS production in kidney tissues in treatment groups suggests that choline or CDP-choline may have therapeutic potential in endotoxemia-associated AKI via downregulating NOX4 and p22phox expressions (Tab."8.31Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats. ( Arici, MA; Baris, E; Simsek, O; Tosun, M, 2023)
"Endotoxemia treatment options are still of interest due to high mortality and choline treatment is one of them because of its role in the cholinergic anti-inflammatory pathway."5.30Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration. ( Cansev, M; Ceron, JJ; Eralp Inan, O; Kasap, S; Kocaturk, M; Rubio, CP; Tvarijonaviciute, A; Ulus, IH; Yilmaz, Z, 2019)
"The available literature has proposed mechanisms for an association between gut microbiota and NASH, such as: modification energy homeostasis, lipopolysaccharides (LPS)-endotoxemia, increased endogenous production of ethanol, and alteration in the metabolism of bile acid and choline."4.98Influence of gut microbiota on the development and progression of nonalcoholic steatohepatitis. ( Cesar, DE; de Castro Ferreira, LEVV; de Faria Ghetti, F; de Oliveira, JM; Moreira, APB; Oliveira, DG, 2018)
"Decreased ROS production in kidney tissues in treatment groups suggests that choline or CDP-choline may have therapeutic potential in endotoxemia-associated AKI via downregulating NOX4 and p22phox expressions (Tab."4.31Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats. ( Arici, MA; Baris, E; Simsek, O; Tosun, M, 2023)
") choline treatment on serum matrix metalloproteinases (MMP), MMP tissue inhibitors (TIMP) and immunoglobulins (Igs), and to determine if there were relations between serum MMPs/TIMPs and C-reactive protein (CRP) (as a marker of the acute phase response), immunoglobulin G and M (IgG and IgM) (as a maker of the Ig responses) and markers of organ damage such as muscular damage (creatine phosphokinase, [CPK]), liver damage (alanine aminotransferase [ALT]) and renal dysfunction (blood urea nitrogen [BUN] and creatinine, [Cr]) in dogs with endotoxemia."3.83Effects of choline treatment in concentrations of serum matrix metalloproteinases (MMPs), MMP tissue inhibitors (TIMPs) and immunoglobulins in an experimental model of canine sepsis. ( Cansev, M; Ceron, JJ; Eralp-Inan, O; Kahraman, MM; Kocaturk, M; Ozyigit, MO; Tvarijonaviciute, A; Yilmaz, Z, 2016)
"This study in dogs was performed to assess circulating choline status during endotoxemia and to determine whether choline administration can protect dogs from endotoxin-induced tissue injuries."3.73Endotoxin alters serum-free choline and phospholipid-bound choline concentrations, and choline administration attenuates endotoxin-induced organ injury in dogs. ( Ilcol, YO; Ulus, IH; Yilmaz, Z, 2005)
"Choline treatment alters the NSP response to LPS."3.01Nasal secretory protein changes following intravenous choline administration in calves with experimentally induced endotoxaemia. ( Baykal, AT; Cansev, M; Ceron, JJ; Inan, OE; Kocaturk, M; Sahin, B; Tvarijonaviciute, A; Ulus, IH; Yilmaz, Z, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Baris, E2
Simsek, O2
Arici, MA2
Tosun, M2
Lv, S1
Zhang, Z1
Su, X1
Li, W1
Wang, X1
Pan, B1
Li, H1
Zhang, H1
Wang, Y1
Kocaturk, M5
Inan, OE1
Tvarijonaviciute, A4
Sahin, B1
Baykal, AT1
Cansev, M5
Ceron, JJ4
Yilmaz, Z6
Ulus, IH4
de Faria Ghetti, F1
Oliveira, DG1
de Oliveira, JM1
de Castro Ferreira, LEVV1
Cesar, DE1
Moreira, APB1
Eralp Inan, O1
Rubio, CP1
Kasap, S1
Eralp-Inan, O1
Ozyigit, MO1
Kahraman, MM1
Ozarda, Y1
Eralp, O1
Musso, G1
Gambino, R1
Cassader, M1
Tecles, F1
Ilcol, YO1

Reviews

2 reviews available for choline and Endotoxemia

ArticleYear
Influence of gut microbiota on the development and progression of nonalcoholic steatohepatitis.
    European journal of nutrition, 2018, Volume: 57, Issue:3

    Topics: Animals; Bile Acids and Salts; Choline; Diet; Disease Progression; Dysbiosis; Endotoxemia; Energy In

2018
Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes.
    Annual review of medicine, 2011, Volume: 62

    Topics: Angiopoietin-Like Protein 4; Angiopoietins; Animals; Bile Acids and Salts; Carbohydrate Metabolism;

2011

Trials

2 trials available for choline and Endotoxemia

ArticleYear
Nasal secretory protein changes following intravenous choline administration in calves with experimentally induced endotoxaemia.
    Veterinary immunology and immunopathology, 2021, Volume: 233

    Topics: Animals; Bodily Secretions; Cattle; Choline; Drug Interactions; Endotoxemia; Gene Expression Regulat

2021
Serum choline and butyrylcholinesterase changes in response to endotoxin in calves receiving intravenous choline administration.
    Research in veterinary science, 2019, Volume: 125

    Topics: Acute-Phase Reaction; Administration, Intravenous; Animals; Biomarkers; Butyrylcholinesterase; Cattl

2019

Other Studies

6 other studies available for choline and Endotoxemia

ArticleYear
Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats.
    Bratislavske lekarske listy, 2023, Volume: 124, Issue:1

    Topics: Acute Kidney Injury; Animals; Choline; Cytidine Diphosphate Choline; Endotoxemia; Kidney; Lipopolysa

2023
Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats.
    Bratislavske lekarske listy, 2023, Volume: 124, Issue:1

    Topics: Acute Kidney Injury; Animals; Choline; Cytidine Diphosphate Choline; Endotoxemia; Kidney; Lipopolysa

2023
Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats.
    Bratislavske lekarske listy, 2023, Volume: 124, Issue:1

    Topics: Acute Kidney Injury; Animals; Choline; Cytidine Diphosphate Choline; Endotoxemia; Kidney; Lipopolysa

2023
Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats.
    Bratislavske lekarske listy, 2023, Volume: 124, Issue:1

    Topics: Acute Kidney Injury; Animals; Choline; Cytidine Diphosphate Choline; Endotoxemia; Kidney; Lipopolysa

2023
Qingrequzhuo capsule alleviated methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice through regulating gut microbiota, enhancing gut tight junction and inhibiting the activation of TLR4/NF-κB signaling pathway.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Animals; Choline; Diet; Drugs, Chinese Herbal; Endotoxemia; Gastrointestinal Microbiome; Inflammatio

2022
Effects of choline treatment in concentrations of serum matrix metalloproteinases (MMPs), MMP tissue inhibitors (TIMPs) and immunoglobulins in an experimental model of canine sepsis.
    Veterinary immunology and immunopathology, 2016, Nov-01, Volume: 180

    Topics: Animals; C-Reactive Protein; Choline; Disease Models, Animal; Dogs; Endotoxemia; Immunoglobulin G; I

2016
Choline or CDP-choline attenuates coagulation abnormalities and prevents the development of acute disseminated intravascular coagulation in dogs during endotoxemia.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2010, Volume: 21, Issue:4

    Topics: Animals; Blood Coagulation; Choline; Cytidine Diphosphate Choline; Disseminated Intravascular Coagul

2010
Serum butyrylcholinesterase and paraoxonase 1 in a canine model of endotoxemia: effects of choline administration.
    Research in veterinary science, 2012, Volume: 93, Issue:2

    Topics: Animals; Aryldialkylphosphatase; Body Temperature; Butyrylcholinesterase; Choline; Dog Diseases; Dog

2012
Endotoxin alters serum-free choline and phospholipid-bound choline concentrations, and choline administration attenuates endotoxin-induced organ injury in dogs.
    Shock (Augusta, Ga.), 2005, Volume: 24, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Choline; Creatine

2005