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choline and Dyskinesia, Drug-Induced

choline has been researched along with Dyskinesia, Drug-Induced in 47 studies

Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)

Research Excerpts

ExcerptRelevanceReference
"The hypotheses of relative cholinergic underactivity in Huntington's disease, tardive dyskinesia, mania, and schizophrenia were pharmacologically investigated, using physostigmine and choline chloride."9.04Pharmacological investigations of the cholinergic imbalance hypotheses of movement disorders and psychosis. ( Berger, PA; Davis, KL, 1978)
"The hypotheses of relative cholinergic underactivity in Huntington's disease, tardive dyskinesia, mania, and schizophrenia were pharmacologically investigated, using physostigmine and choline chloride."5.04Pharmacological investigations of the cholinergic imbalance hypotheses of movement disorders and psychosis. ( Berger, PA; Davis, KL, 1978)
" Although neuroleptics are significantly superior to most other methods of treatment in suppressing signs of dyskinesia, the safety of their long-term use in dyskinetic patients remains to be demonstrated."3.75Therapeutic strategies against tardive dyskinesia. Two decades of experience. ( Jeste, DV; Wyatt, RJ, 1982)
"Deanol was not found to be effective in this group of patients; the authors suggest that this drug should not be assumed to be generally effective unless effectiveness is verified by a large placebo-controlled double-blind study."2.64Cholinergic influences in tardive dyskinesia. ( Chang, S; Davis, JM; Ericksen, SE; Smith, RC; Tamminga, CA, 1977)
"Deanol did not produce the anticipated elevation in choline levels postulated to be one mechanism of its action."1.26Deanol acetamidobenzoate (Deaner) in tardive dyskinesia. ( Fann, WE; Stafford, JR, 1977)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199045 (95.74)18.7374
1990's1 (2.13)18.2507
2000's1 (2.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ando, K1
Takei, N1
Matsumoto, H1
Iyo, M1
Isoda, H1
Mori, N1
Berger, PA6
Rexroth, K1
Jeste, DV1
Wyatt, RJ1
Alphs, LD1
Davis, JM3
Nasrallah, HA2
Dunner, FJ2
Smith, RE2
McCalley-Whitters, M2
Sherman, AD1
Growdon, JH11
Wheeler, S1
Graham, HN1
Volavka, J1
Lifshitz, K1
Friedman, E1
Sherman, KA1
Banay-Schwartz, M1
Arranz, J1
Ganoza, C1
Zeisel, SH1
Gelenberg, AJ6
Wurtman, RJ8
Ansell, GB1
Ray, R1
Ramakrishnan, N1
Rao, BS1
Jackson, IV1
Davis, LG1
Cohen, RK1
Nuttall, EA1
Corkin, S1
Clayton, MR1
Snell, AP1
Cleary, M1
Sambrook, M1
Casey, DE1
Tamminga, C1
Smith, RC2
Chang, S2
Haraszti, JS1
Hirsch, MJ4
Davis, KL6
Hollister, LE5
Barchas, JD1
Simonton, SC1
Barbeau, A1
Vento, AL2
Kolata, GB1
Doller-Wojcik, JC1
Simonton, S1
Pauling, L1
Stafford, JR1
Fann, WE1
Bourgeois, M1
Boueilh, P1
Peyre, C1
Gauthier-Bernard, F1
Doller, J1
Millington, WR1
McCall, AL1
Tamminga, CA1
Ericksen, SE1
Gerlach, J1
Wiener, W1
Weiss, KJ1
Dorer, DJ1
Wojcik, JD1
Falk, WE1
Brotman, AW1
Leahy, L1
DiPalma, JR1

Reviews

5 reviews available for choline and Dyskinesia, Drug-Induced

ArticleYear
Therapeutic strategies against tardive dyskinesia. Two decades of experience.
    Archives of general psychiatry, 1982, Volume: 39, Issue:7

    Topics: Antipsychotic Agents; Choline; Clinical Trials as Topic; Deanol; Dopamine Antagonists; Double-Blind

1982
Cholinergic treatments for tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Acetylcholine; Antipsychotic Agents; Choline; Clinical Trials as Topic; Corpus Striatum; Deanol; Dop

1983
Use of choline and lecithin in the treatment of tardive dyskinesia.
    Advances in biochemical psychopharmacology, 1980, Volume: 24

    Topics: Acetylcholine; Brain Chemistry; Choline; Dyskinesia, Drug-Induced; Humans; Nervous System Diseases;

1980
The biochemical background to tardive dyskinesia.
    Neuropharmacology, 1981, Volume: 20, Issue:4

    Topics: Acetylcholine; Animals; Choline; Deanol; Dyskinesia, Drug-Induced; Humans; Phosphatidylcholines

1981
Emerging treatments: replacement therapy with choline or lecithin in neurological diseases.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1978, Volume: 5, Issue:1

    Topics: Animals; Choline; Dyskinesia, Drug-Induced; Friedreich Ataxia; Humans; Huntington Disease; Nervous S

1978

Trials

13 trials available for choline and Dyskinesia, Drug-Induced

ArticleYear
Therapeutic strategies against tardive dyskinesia. Two decades of experience.
    Archives of general psychiatry, 1982, Volume: 39, Issue:7

    Topics: Antipsychotic Agents; Choline; Clinical Trials as Topic; Deanol; Dopamine Antagonists; Double-Blind

1982
Cholinergic treatments for tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Acetylcholine; Antipsychotic Agents; Choline; Clinical Trials as Topic; Corpus Striatum; Deanol; Dop

1983
Variable clinical response to choline in tardive dyskinesia.
    Psychological medicine, 1984, Volume: 14, Issue:3

    Topics: Acetylcholine; Adult; Aged; Choline; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dou

1984
Pharmacological investigations of the cholinergic imbalance hypotheses of movement disorders and psychosis.
    Biological psychiatry, 1978, Volume: 13, Issue:1

    Topics: Acetylcholine; Adult; Aged; Bipolar Disorder; Brain; Choline; Clinical Trials as Topic; Double-Blind

1978
Dietary enhancement of CNS neurotransmitters.
    Hospital practice, 1978, Volume: 13, Issue:3

    Topics: Acetylcholine; Administration, Oral; Brain; Choline; Clinical Trials as Topic; Diet; Dyskinesia, Dru

1978
Effects of choline on tardive dyskinesia and other movement disorders.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:4

    Topics: Choline; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Phosphatidy

1978
Studies on choline chloride in neuropsychiatric disease: human and animal data.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:4

    Topics: Animals; Choline; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation; Dyskinesia, Dru

1978
Mental disorders: a new approach to treatment?
    Science (New York, N.Y.), 1979, Jan-05, Volume: 203, Issue:4375

    Topics: Acetylcholine; Brain; Choline; Clinical Trials as Topic; Dementia; Double-Blind Method; Dyskinesia,

1979
Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study.
    The American journal of psychiatry, 1979, Volume: 136, Issue:6

    Topics: Adult; Choline; Clinical Trials as Topic; Dyskinesia, Drug-Induced; Humans; Male; Phosphatidylcholin

1979
Cholinergic influences in tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Acetylcholine; Administration, Oral; Basal Ganglia; Choline; Deanol; Dyskinesia, Drug-Induced; Ethan

1977
Oral choline administration to patients with tardive dyskinesia.
    The New England journal of medicine, 1977, Sep-08, Volume: 297, Issue:10

    Topics: Administration, Oral; Adult; Aged; Choline; Dose-Response Relationship, Drug; Drug Evaluation; Drug

1977
A crossover study of lecithin treatment of tardive dyskinesia.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Attitude to Health; Choline; Double-Blind Method; Dyskinesia, Drug-Induced;

1990
Pharmacologic probes of neurotransmitter systems in tardive dyskinesia: implications for clinical management.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aged; Choline; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamin

1986

Other Studies

31 other studies available for choline and Dyskinesia, Drug-Induced

ArticleYear
Neural damage in the lenticular nucleus linked with tardive dyskinesia in schizophrenia: a preliminary study using proton magnetic resonance spectroscopy.
    Schizophrenia research, 2002, Oct-01, Volume: 57, Issue:2-3

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine

2002
Tardive dyskinesia: clinical, biological, and pharmacological perspectives.
    Schizophrenia bulletin, 1980, Volume: 6, Issue:1

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Choline; Corpus Striatum; Diagnosis, Differential; Dop

1980
Plasma choline responses to lecithin-enriched soup.
    Psychopharmacology bulletin, 1984,Summer, Volume: 20, Issue:3

    Topics: Alzheimer Disease; Choline; Dyskinesia, Drug-Induced; Humans; Phosphatidylcholines

1984
Effects of lecithin on EEG and blood levels of choline.
    Biological psychiatry, 1983, Volume: 18, Issue:10

    Topics: Adult; Aged; Choline; Dyskinesia, Drug-Induced; Electroencephalography; Evoked Potentials; Female; H

1983
Treatment of chronic dyskinesia with CDP-choline.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7A

    Topics: Acetylcholine; Choline; Cytidine Diphosphate Choline; Dyskinesia, Drug-Induced; Female; Humans; Midd

1983
Oral choline in tardive dyskinesia.
    The Indian journal of medical research, 1982, Volume: 76

    Topics: Administration, Oral; Choline; Dyskinesia, Drug-Induced; Female; Humans

1982
Lecithin administration in tardive dyskinesia: clinical and biomedical correlates.
    Biological psychiatry, 1981, Volume: 16, Issue:1

    Topics: Choline; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Phosphati

1981
Neurochemical approaches to the treatment of senile dementia.
    Proceedings of the annual meeting of the American Psychopathological Association, 1980, Volume: 69

    Topics: Acetylcholine; Aged; Alzheimer Disease; Animals; Choline; Choline O-Acetyltransferase; Dementia; Dys

1980
Choline in treatment of ataxia.
    The Medical journal of Australia, 1980, Oct-04, Volume: 2, Issue:7

    Topics: Aged; Ataxia; Choline; Dyskinesia, Drug-Induced; Female; Humans

1980
Treatment of tardive dyskinesia with choline and tetrabenazine.
    Postgraduate medical journal, 1980, Volume: 56, Issue:659

    Topics: Aged; Choline; Dyskinesia, Drug-Induced; Female; Humans; Tetrabenazine

1980
Managing tardive dyskinesia.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10

    Topics: Antipsychotic Agents; Choline; Deanol; Dyskinesia, Drug-Induced; Humans; Lithium; Receptors, Dopamin

1978
Depression associated with oral choline.
    Lancet (London, England), 1976, Oct-23, Volume: 2, Issue:7991

    Topics: Administration, Oral; Adult; Choline; Depression; Dyskinesia, Drug-Induced; Female; Humans; Male; Mi

1976
Lecithin consumption raises serum-free-choline levels.
    Lancet (London, England), 1977, Jul-09, Volume: 2, Issue:8028

    Topics: Acetylcholine; Administration, Oral; Adult; Biological Availability; Choline; Dietary Fats; Dyskines

1977
Tardive dyskinesia.
    Lancet (London, England), 1979, Sep-01, Volume: 2, Issue:8140

    Topics: Antipsychotic Agents; Baclofen; Benzodiazepines; Choline; Dyskinesia, Drug-Induced; Humans; Pimozide

1979
Choline in tardive dyskinesia and Huntington's disease.
    Life sciences, 1976, Nov-15, Volume: 19, Issue:10

    Topics: Choline; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Male; Physostigmine

1976
Choline chloride in the treatment of Huntington's disease and tardive dyskinesia: a preliminary report.
    Psychopharmacology bulletin, 1977, Volume: 13, Issue:3

    Topics: Choline; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Physostigmine

1977
Choline and lecithin for the treatment of tardive dyskinesia [proceedings].
    Psychopharmacology bulletin, 1979, Volume: 15, Issue:2

    Topics: Adult; Choline; Dyskinesia, Drug-Induced; Humans; Male; Phosphatidylcholines

1979
Choline chloride in animal models of tardive dyskinesia.
    Life sciences, 1978, May-15, Volume: 22, Issue:19

    Topics: Animals; Apomorphine; Choline; Disease Models, Animal; Dyskinesia, Drug-Induced; Haloperidol; Humans

1978
Treating mental disorders.
    Science (New York, N.Y.), 1979, Oct-26, Volume: 206, Issue:4417

    Topics: Choline; Dyskinesia, Drug-Induced; Humans; Mental Disorders

1979
Deanol acetamidobenzoate (Deaner) in tardive dyskinesia.
    Diseases of the nervous system, 1977, Volume: 38, Issue:12 Pt 2

    Topics: Choline; Cyproheptadine; Deanol; Drug Evaluation; Dyskinesia, Drug-Induced; Ethanolamines; Humans; M

1977
[Neuroleptic tardive dyskinesias. Completion of the inquiry regarding 1,480 psychiatric hospital patients].
    Annales medico-psychologiques, 1977, Volume: 1, Issue:4

    Topics: Age Factors; Aged; Child; Choline; Dyskinesia, Drug-Induced; Female; Hospitals, Psychiatric; Humans;

1977
Lecithin can suppress tardive dyskinesia.
    The New England journal of medicine, 1978, May-04, Volume: 298, Issue:18

    Topics: Choline; Dyskinesia, Drug-Induced; Humans; Phosphatidylcholines

1978
Lecithin consumption increases acetylcholine concentrations in rat brain and adrenal gland.
    Science (New York, N.Y.), 1978, Oct-13, Volume: 202, Issue:4364

    Topics: Acetylcholine; Adrenal Glands; Animals; Brain; Choline; Diet; Dyskinesia, Drug-Induced; Male; Phosph

1978
Nutritional and precursor control of brain acetylcholine synthesis.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:4

    Topics: Acetylcholine; Animals; Brain; Choline; Dyskinesia, Drug-Induced; Humans

1978
Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline.
    Annals of neurology, 1978, Volume: 4, Issue:4

    Topics: Acetylcholine; Animals; Blood-Brain Barrier; Brain; Brain Chemistry; Choline; Deanol; Dyskinesia, Dr

1978
Choline and lecithin administration to patients with tardive dyskinesia.
    Transactions of the American Neurological Association, 1978, Volume: 103

    Topics: Choline; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Phosphatidylcholines

1978
The relationship between parkinsonism and tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Age Factors; Aminobutyrates; Baclofen; Basal Ganglia; Biperiden; Choline; Dopamine; Dyskinesia, Drug

1977
Deanol in tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Acetylcholine; Choline; Deanol; Dyskinesia, Drug-Induced; Ethanolamines; Humans

1977
Choline for tardive dyskinesia.
    The New England journal of medicine, 1977, Dec-01, Volume: 297, Issue:22

    Topics: Choline; Dyskinesia, Drug-Induced; Humans; Parasympatholytics

1977
Nutritional pharmacology.
    American family physician, 1985, Volume: 32, Issue:2

    Topics: Amino Acids, Branched-Chain; Brain Diseases; Choline; Diet; Dyskinesia, Drug-Induced; Hepatic Enceph

1985
Phosphatidylcholine and tardive dyskinesia.
    Biological psychiatry, 1986, Volume: 21, Issue:7

    Topics: Acetylcholine; Choline; Dyskinesia, Drug-Induced; Humans; Phosphatidylcholines

1986