Page last updated: 2024-10-17

choline and Drug Withdrawal Symptoms

choline has been researched along with Drug Withdrawal Symptoms in 23 studies

Research Excerpts

ExcerptRelevanceReference
"Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function."6.71Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003)
"Cholinergic and anticholinergic agents were tested against the induction and expression of morphine dependence in rats."3.65Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat. ( Frederickson, RC; Pinsky, C, 1975)
"Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function."2.71Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003)
"hexamethonium (2 mg/kg) pretreatment did not abolish the increase in the heart rate, but it delayed the blood pressure increase."1.28Yohimbine-precipitated clonidine withdrawal: an experimental model of the antihypertensive drug withdrawal syndrome. ( Jhamandas, K; Penning, DH, 1992)
"RBC choline concentration was significantly lower in patients medicated with neuroleptics and cogentin."1.28RBC and plasma choline in neuroleptic-treated schizophrenic patients. ( Hanin, I; Jeste, DV; Kopp, U; Lawson, WB; Wyatt, RJ, 1989)
"When atropine was administered to M mice 10 min before sacrifice, brain AC-h levels decreased."1.26Morphine tolerance and physical dependence: influence of cholinergic agonists and antagonists. ( Bhargava, HN; Way, EL, 1976)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's2 (8.70)18.2507
2000's5 (21.74)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zahr, NM1
Mayer, D1
Vinco, S1
Orduna, J1
Luong, R1
Sullivan, EV2
Pfefferbaum, A2
Nordahl, TE2
Salo, R2
Possin, K1
Gibson, DR1
Flynn, N1
Leamon, M1
Galloway, GP2
Spielman, DM1
Adalsteinsson, E1
Kaufman, MJ1
Henry, ME1
Frederick, Bd1
Hennen, J1
Villafuerte, RA1
Stoddard, EP1
Schmidt, ME1
Cohen, BM1
Renshaw, PF1
Celik, T1
Kayir, H1
Ceyhan, M1
Demirtaş, S1
Coşar, A1
Uzbay, IT1
Natsuaki, Y1
Waters, C1
Moore, CD1
Kile, S1
Buonocore, MH1
Murrin, LC1
Kennedy, RH1
Donnelly, TE1
Alphs, LD1
Davis, JM1
Pomara, N1
Block, R1
Domino, EF2
Gershon, S1
Tornos, ME1
Sacristán, A1
Ortiz, JA1
Lipper, S1
Landau, SG1
Domino, SE1
Casamenti, F1
Pedata, F1
Corradetti, R1
Pepeu, G1
Casey, DE1
Bhargava, HN4
Way, EL4
Frederickson, RC2
Pinsky, C2
Cheney, DL1
Trabucchi, M1
Hanin, I2
Costa, E1
Natsuki, R1
Penning, DH1
Jhamandas, K1
Lawson, WB1
Jeste, DV1
Kopp, U1
Wyatt, RJ1
Chan, SL1
Vazquez, AJ1
Jönsson, LE1
Schuberth, J1
Sundwall, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070]68 participants (Actual)Interventional2007-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for choline and Drug Withdrawal Symptoms

ArticleYear
Cholinergic treatments for tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Acetylcholine; Antipsychotic Agents; Choline; Clinical Trials as Topic; Corpus Striatum; Deanol; Dop

1983

Trials

3 trials available for choline and Drug Withdrawal Symptoms

ArticleYear
Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study.
    Biological psychiatry, 2003, Sep-01, Volume: 54, Issue:5

    Topics: Adult; Brain Mapping; Choline; Depressive Disorder, Major; Female; Fluoxetine; Gyrus Cinguli; Humans

2003
Cholinergic treatments for tardive dyskinesia.
    Modern problems of pharmacopsychiatry, 1983, Volume: 21

    Topics: Acetylcholine; Antipsychotic Agents; Choline; Clinical Trials as Topic; Corpus Striatum; Deanol; Dop

1983
Influence of hemicholinium (HC-3) on morphine analgesia, tolerance, physical dependence and on brain acetylcholine.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Acetylcholine; Analgesia; Animals; Body Weight; Brain; Brain Chemistry; Choline; Drug Tolerance; Hem

1974

Other Studies

20 other studies available for choline and Drug Withdrawal Symptoms

ArticleYear
In vivo evidence for alcohol-induced neurochemical changes in rat brain without protracted withdrawal, pronounced thiamine deficiency, or severe liver damage.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009, Volume: 34, Issue:6

    Topics: Animals; Basal Ganglia; Choline; Ethanol; Fatty Liver; Glutamic Acid; Glutamine; Glycogen Storage Di

2009
Low N-acetyl-aspartate and high choline in the anterior cingulum of recently abstinent methamphetamine-dependent subjects: a preliminary proton MRS study. Magnetic resonance spectroscopy.
    Psychiatry research, 2002, Nov-30, Volume: 116, Issue:1-2

    Topics: Adult; Age Factors; Amphetamine-Related Disorders; Aspartic Acid; Choline; Creatine; Dopamine; Front

2002
CPP and amlodipine alter the decrease in basal acetylcholine and choline release by audiogenic stimulus in hippocampus of ethanol-withdrawn rats in vivo.
    Brain research bulletin, 2004, Sep-30, Volume: 64, Issue:3

    Topics: Acetylcholine; Acoustic Stimulation; Alcohol-Induced Disorders, Nervous System; Amlodipine; Animals;

2004
Methamphetamine users in sustained abstinence: a proton magnetic resonance spectroscopy study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:4

    Topics: Adult; Ambulatory Care; Amphetamine-Related Disorders; Aspartic Acid; Brain; Choline; Creatine; Dopa

2005
Effect of withdrawal from chronic propranolol treatment on high-affinity choline uptake in rat brain.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:10

    Topics: Animals; Brain; Choline; Humans; Male; Propranolol; Rats; Rats, Inbred Strains; Reserpine; Substance

1983
Decay in plasma lithium and normalization in red blood cell choline following cessation of lithium treatment in two elderly individuals with Alzheimer-type dementia.
    Biological psychiatry, 1984, Volume: 19, Issue:6

    Topics: Aged; Alzheimer Disease; Choline; Erythrocytes; Humans; Lithium; Lithium Carbonate; Male; Substance

1984
Effect of oral CDP-choline on experimental withdrawal syndrome.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:7A

    Topics: Animals; Behavior, Animal; Body Temperature; Choline; Cytidine Diphosphate Choline; Humans; Male; Mi

1983
Levels of red blood cell choline after discontinuation of lithium therapy.
    The American journal of psychiatry, 1982, Volume: 139, Issue:5

    Topics: Adult; Bipolar Disorder; Choline; Erythrocytes; Humans; Lithium; Lithium Carbonate; Male; Substance

1982
Acetylcholine input from the cerebral cortex, choline uptake and muscarinic receptors in morphine-dependent, freely-moving rats.
    Neuropharmacology, 1980, Volume: 19, Issue:7

    Topics: Acetylcholine; Animals; Brain; Calcium; Cerebral Cortex; Choline; Humans; Male; Morphine Dependence;

1980
Managing tardive dyskinesia.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:10

    Topics: Antipsychotic Agents; Choline; Deanol; Dyskinesia, Drug-Induced; Humans; Lithium; Receptors, Dopamin

1978
Morphine tolerance and physical dependence: influence of cholinergic agonists and antagonists.
    European journal of pharmacology, 1976, Volume: 36, Issue:1

    Topics: Acetylcholine; Analgesia; Animals; Atropine; Brain; Choline; Drug Synergism; Drug Tolerance; Humans;

1976
Effects of cholinergic and anticholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence on morphine in rat.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:1

    Topics: Animals; Atropine; Body Weight; Choline; Humans; Male; Mecamylamine; Morphine Dependence; Parasympat

1975
Brain acetylcholine and choline following acute and chronic morphine treatment and during withdrawal.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:1

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Brain Chemistry; Choline; Chromatography, Gas; Delayed

1975
Morphine dependence and in vivo turnover of acetylcholine in whole mouse brain.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 195, Issue:2

    Topics: Acetylcholine; Animals; Brain; Choline; Drug Implants; Humans; Injections, Intraperitoneal; Kinetics

1975
Relationship between incorporation of choline into phosphatidylcholine and morphine binding sites.
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1992, Volume: 27, Issue:1

    Topics: Animals; Brain; Calcium; Choline; In Vitro Techniques; Mice; Morphine; Morphine Dependence; Naloxone

1992
Yohimbine-precipitated clonidine withdrawal: an experimental model of the antihypertensive drug withdrawal syndrome.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6

    Topics: Animals; Antihypertensive Agents; Atropine; Blood Pressure; Central Nervous System; Choline; Clonidi

1992
RBC and plasma choline in neuroleptic-treated schizophrenic patients.
    Psychiatry research, 1989, Volume: 29, Issue:1

    Topics: Adult; Antipsychotic Agents; Brain; Choline; Chronic Disease; Erythrocytes; Female; Haloperidol; Hum

1989
Morphine withdrawal syndrome responses to cholinergic antagonists and to a partial cholinergic agonist.
    Nature, 1973, Mar-02, Volume: 242, Issue:5392

    Topics: Animals; Atropine; Choline; Humans; Male; Mecamylamine; Morphine Dependence; Rats; Substance Withdra

1973
Effect of 1-phenyl-3-(2-thiazolyl)-2-thiourea, a dopamine beta-hydroxylase inhibitor on morphine analgesia, tolerance and physical dependence.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 190, Issue:1

    Topics: Acetylcholine; Analgesia; Animals; Behavior, Animal; Body Weight; Brain; Choline; Chromatography, Ga

1974
Amphetamine effect on the choline concentration of human cerebrospinal fluid.
    Life sciences, 1969, Sep-01, Volume: 8, Issue:17

    Topics: Acetylcholine; Adolescent; Adult; Amphetamine; Brain; Choline; Female; Humans; Male; Substance Withd

1969