Page last updated: 2024-10-16

choline and Diabetes, Gestational

choline has been researched along with Diabetes, Gestational in 7 studies

Diabetes, Gestational: Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.

Research Excerpts

ExcerptRelevanceReference
" The World Health Organisation recommends folic acid (FA) supplementation pre-conception and in early pregnancy to reduce the risk of fetal neural tube defects (NTDs)."5.22High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus. ( Arthurs, AL; Jankovic-Karasoulos, T; Roberts, CT; Smith, MD; Williamson, JM, 2022)
"Both insufficiency and excess of one-carbon nutrients (folate, choline, vitamins B6 and B12) during pregnancy have been associated with gestational diabetes mellitus (GDM)."3.88Fetal one-carbon nutrient concentrations may be affected by gestational diabetes. ( Barzilay, E; Berger, H; Caudill, MA; Croxford, R; Kim, YI; Ly, A; Malysheva, O; Masih, SP; Moon, A; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE, 2018)
"Gestational diabetes is a metabolic disorder affecting 2-5% of women and is a predictor of obesity, Type 2 diabetes mellitus and cardiovascular disease."1.32Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic acids in gestational diabetes. ( Crawford, MA; Ghebremeskel, K; Lowy, C; Min, Y; Thomas, B, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Fernandez-Osornio, LF1
Gomez-Diaz, RA1
Mondragon-Gonzalez, R1
Gonzalez-Carranza, E1
Diaz-Flores, M1
Sharma, T1
Hernández-Pineda, J1
Maldonado-Rodriguez, R1
Wacher, NH1
Cruz, M1
Valladares-Salgado, A1
Williamson, JM1
Arthurs, AL1
Smith, MD1
Roberts, CT1
Jankovic-Karasoulos, T1
Lin, X1
Zhang, Y1
He, X1
Chen, Y1
Chen, N1
Liu, J2
Wang, M1
Li, Y1
Yang, H1
Fan, L1
Hou, Y1
Li, J2
Wu, C1
Qi, H1
Zhang, H1
Xiao, X1
Barzilay, E1
Moon, A1
Plumptre, L1
Masih, SP1
Sohn, KJ1
Visentin, CE1
Ly, A1
Malysheva, O1
Croxford, R1
Caudill, MA1
O'Connor, DL1
Kim, YI1
Berger, H1
Nanobashvili, K1
Jack-Roberts, C1
Bretter, R1
Jones, N1
Axen, K1
Saxena, A1
Blain, K1
Jiang, X1
Huo, X1
Cao, YF1
Li, SN1
Shao, P1
Leng, J1
Li, W1
Yang, K1
Ma, RCW1
Hu, G1
Fang, ZZ1
Yang, X1
Min, Y1
Ghebremeskel, K1
Lowy, C1
Thomas, B1
Crawford, MA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus[NCT04302168]60 participants (Anticipated)Interventional2020-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for choline and Diabetes, Gestational

ArticleYear
High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus.
    Nutrients, 2022, Sep-22, Volume: 14, Issue:19

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Carbon; Choline; Diabet

2022

Other Studies

6 other studies available for choline and Diabetes, Gestational

ArticleYear
Micronutrients of the one-carbon metabolism cycle are altered in mothers and neonates by gestational diabetes and are associated with weight, height and head circumference at birth.
    The Journal of nutritional biochemistry, 2022, Volume: 105

    Topics: Betaine; Birth Weight; Carbon; Choline; Diabetes, Gestational; Female; Folic Acid; Glycine; Humans;

2022
The Choline Metabolite TMAO Inhibits NETosis and Promotes Placental Development in GDM of Humans and Mice.
    Diabetes, 2021, Volume: 70, Issue:10

    Topics: Adult; Animals; Case-Control Studies; Cells, Cultured; Choline; Diabetes, Gestational; Extracellular

2021
Fetal one-carbon nutrient concentrations may be affected by gestational diabetes.
    Nutrition research (New York, N.Y.), 2018, Volume: 55

    Topics: Adult; Betaine; Carbon; Choline; Diabetes, Gestational; Female; Fetal Blood; Fetal Development; Fetu

2018
Maternal Choline and Betaine Supplementation Modifies the Placental Response to Hyperglycemia in Mice and Human Trophoblasts.
    Nutrients, 2018, Oct-15, Volume: 10, Issue:10

    Topics: Animal Feed; Animals; Betaine; Biomarkers; Blood Glucose; Cell Line, Tumor; Choline; Diabetes, Gesta

2018
Trimethylamine N-Oxide Metabolites in Early Pregnancy and Risk of Gestational Diabetes: A Nested Case-Control Study.
    The Journal of clinical endocrinology and metabolism, 2019, 11-01, Volume: 104, Issue:11

    Topics: Adult; Betaine; Blood Glucose; Carnitine; Case-Control Studies; China; Choline; Diabetes, Gestationa

2019
Adverse effect of obesity on red cell membrane arachidonic and docosahexaenoic acids in gestational diabetes.
    Diabetologia, 2004, Volume: 47, Issue:1

    Topics: Adult; Arachidonic Acid; Choline; Diabetes Mellitus; Diabetes, Gestational; Docosahexaenoic Acids; E

2004