choline has been researched along with Depression, Involutional in 51 studies
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function." | 6.71 | Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003) |
| "Discontinuation syndrome is associated with a rostral anterior cingulate Cho/Cre metabolite ratio decrease that may reflect dynamics of rostral anterior cingulate function." | 2.71 | Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study. ( Cohen, BM; Frederick, Bd; Hennen, J; Henry, ME; Kaufman, MJ; Renshaw, PF; Schmidt, ME; Stoddard, EP; Villafuerte, RA, 2003) |
| "Smaller hippocampal volumes in major depressive disorder (MDD) have been linked with earlier onset, previous recurrences and treatment refractoriness." | 1.39 | Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden. ( Álvarez, E; de Diego-Adeliño, J; Gómez-Ansón, B; López-Moruelo, O; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Serra-Blasco, M; Vives, Y, 2013) |
| "Seventy-five elderly patients with major depressive disorder in remission underwent assessment of insight using the Mood Disorders Insight Scale (MDIS), including awareness, attribution, and need for treatment." | 1.36 | Brain proton magnetic resonance spectroscopic study of insight among elders with late-life depression in remission. ( Chang, HC; Chen, CS; Ko, CH; Kuo, YT; Li, CW; Lin, HF; Liu, GC; Yeh, YC; Yen, CF, 2010) |
| "Patients with late-life major depressive disorder had a significantly lower NAA/creatine ratio in the left frontal white matter, and higher Cho/creatine and myo-inositol/creatine ratios in the left basal ganglia when compared with the control subjects." | 1.35 | Proton magnetic resonance spectroscopy of late-life major depressive disorder. ( Chen, CS; Chiang, IC; Hsieh, TJ; Kuo, YT; Li, CW; Lin, HF; Lin, WC; Liu, GC; Lu, CY, 2009) |
| "The neural underpinnings of major depressive disorder (MDD) are unknown but there is evidence for structural alteration in the hippocampus that may become more pronounced over the course of illness." | 1.35 | Hippocampal metabolic abnormalities at first onset and with recurrent episodes of a major depressive disorder: a proton magnetic resonance spectroscopy study. ( Hall, GB; MacQueen, GM; Milne, A; Soreni, N; Yucel, K, 2009) |
| "Patients with type 2 diabetes and major depression (n=20) were scanned along with patients with diabetes alone (n=24) and healthy controls (n=21) on a 1." | 1.34 | Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. ( Ajilore, O; Binesh, N; Darwin, C; Haroon, E; Kumar, A; Kumaran, S; Miller, J; Mintz, J; Thomas, MA, 2007) |
| "Tolcapone is a catechol-O-methyltransferase (COMT) inhibitor that has shown efficacy in the treatment of Parkinson's disease." | 1.30 | Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder. ( Alpert, JE; Bottiglieri, T; Fava, M; Kolsky, AR; Magni, G; Moore, C; Moroz, G; Nierenberg, AA; Renshaw, P; Rosenbaum, JF; Spillmann, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.96) | 18.2507 |
| 2000's | 24 (47.06) | 29.6817 |
| 2010's | 19 (37.25) | 24.3611 |
| 2020's | 7 (13.73) | 2.80 |
| Authors | Studies |
|---|---|
| Lv, S | 2 |
| Zhong, S | 7 |
| Zhang, S | 1 |
| Lai, S | 5 |
| Wang, Y | 9 |
| Zhao, H | 3 |
| Zhang, Y | 3 |
| Luo, Y | 2 |
| Yan, S | 2 |
| Ran, H | 2 |
| Chen, P | 4 |
| Chen, G | 3 |
| Jia, Y | 9 |
| Wu, W | 1 |
| He, J | 2 |
| Zhu, Y | 3 |
| Qi, Z | 1 |
| Song, Z | 2 |
| Hu, Y | 1 |
| Miao, H | 2 |
| Huang, X | 2 |
| Lu, X | 2 |
| Liu, X | 1 |
| Ye, K | 1 |
| Duan, M | 1 |
| Song, K | 1 |
| Güleş, E | 1 |
| Iosifescu, DV | 1 |
| Tural, Ü | 1 |
| Kahl, KG | 1 |
| Atalay, S | 1 |
| Maudsley, AA | 1 |
| Sheriff, S | 1 |
| Cummings, A | 1 |
| Frieling, H | 1 |
| Schmitz, B | 1 |
| Lanfermann, H | 1 |
| Ding, XQ | 1 |
| Badamasi, IM | 1 |
| Maulidiani, M | 1 |
| Lye, MS | 1 |
| Ibrahim, N | 1 |
| Shaari, K | 1 |
| Stanslas, J | 1 |
| Freed, RD | 1 |
| Hollenhorst, CN | 1 |
| Weiduschat, N | 1 |
| Mao, X | 2 |
| Kang, G | 2 |
| Shungu, DC | 2 |
| Gabbay, V | 3 |
| Shan, Y | 1 |
| Li, X | 1 |
| Chen, J | 1 |
| Lu, Q | 1 |
| Zhang, L | 1 |
| Li, Z | 1 |
| Riley, CA | 1 |
| Renshaw, PF | 3 |
| Tang, Y | 1 |
| Zhang, X | 2 |
| Sheng, J | 1 |
| Zhang, J | 3 |
| Xu, J | 1 |
| Wang, J | 2 |
| Zhang, T | 1 |
| Tong, S | 1 |
| Ning, L | 1 |
| Liu, M | 1 |
| Li, Y | 1 |
| de Diego-Adeliño, J | 2 |
| Portella, MJ | 2 |
| Gómez-Ansón, B | 2 |
| López-Moruelo, O | 1 |
| Serra-Blasco, M | 1 |
| Vives, Y | 2 |
| Puigdemont, D | 2 |
| Pérez-Egea, R | 2 |
| Álvarez, E | 1 |
| Pérez, V | 2 |
| Tae, WS | 1 |
| Kim, SS | 1 |
| Lee, KU | 1 |
| Nam, EC | 1 |
| Koh, SH | 1 |
| Chen, LP | 1 |
| Dai, HY | 1 |
| Dai, ZZ | 1 |
| Xu, CT | 2 |
| Wu, RH | 2 |
| Shi, XF | 1 |
| Forrest, LN | 1 |
| Kuykendall, MD | 1 |
| Prescot, AP | 1 |
| Sung, YH | 1 |
| Huber, RS | 1 |
| Hellem, TL | 1 |
| Jeong, EK | 1 |
| Kondo, DG | 1 |
| Zhao, G | 1 |
| Xiang, Q | 1 |
| Ling, X | 3 |
| Liu, S | 4 |
| Huang, L | 4 |
| Liu, T | 1 |
| Liao, X | 1 |
| Bradley, KA | 1 |
| Case, JA | 1 |
| Yang, XR | 1 |
| Langevin, LM | 1 |
| Jaworska, N | 1 |
| Kirton, A | 1 |
| Lebel, RM | 1 |
| Harris, AD | 1 |
| Jasaui, Y | 1 |
| Wilkes, TC | 1 |
| Sembo, M | 1 |
| Swansburg, R | 1 |
| MacMaster, FP | 3 |
| Tan, HZ | 1 |
| Li, H | 1 |
| Liu, CF | 1 |
| Guan, JT | 1 |
| Guo, XB | 1 |
| Wen, CH | 1 |
| Ou, SM | 1 |
| Zhang, YN | 1 |
| Shen, ZW | 1 |
| Wang, XQ | 1 |
| Murck, H | 1 |
| Schubert, MI | 1 |
| Schmid, D | 1 |
| Schüssler, P | 1 |
| Steiger, A | 1 |
| Auer, DP | 2 |
| Moore, GJ | 3 |
| Russell, A | 3 |
| Mirza, Y | 2 |
| Taormina, SP | 1 |
| Buhagiar, C | 1 |
| Rosenberg, DR | 3 |
| Block, W | 1 |
| Träber, F | 1 |
| von Widdern, O | 1 |
| Metten, M | 1 |
| Schild, H | 1 |
| Maier, W | 1 |
| Zobel, A | 1 |
| Jessen, F | 1 |
| Venkatraman, TN | 1 |
| Krishnan, RR | 1 |
| Steffens, DC | 1 |
| Song, AW | 1 |
| Taylor, WD | 1 |
| Chen, CS | 2 |
| Chiang, IC | 1 |
| Li, CW | 2 |
| Lin, WC | 1 |
| Lu, CY | 1 |
| Hsieh, TJ | 1 |
| Liu, GC | 2 |
| Lin, HF | 2 |
| Kuo, YT | 2 |
| Milne, A | 1 |
| MacQueen, GM | 1 |
| Yucel, K | 1 |
| Soreni, N | 1 |
| Hall, GB | 1 |
| Kaymak, SU | 1 |
| Demir, B | 1 |
| Oğuz, KK | 1 |
| Sentürk, S | 1 |
| Uluğ, B | 1 |
| Rao, V | 1 |
| Munro, CA | 1 |
| Rosenberg, P | 1 |
| Ward, J | 1 |
| Bertrand, M | 1 |
| Degoankar, M | 1 |
| Horská, A | 1 |
| Pham, D | 1 |
| Yousem, DM | 1 |
| Barker, PB | 1 |
| Ko, CH | 1 |
| Yeh, YC | 1 |
| Chang, HC | 1 |
| Yen, CF | 1 |
| Morgan-Ferrando, R | 1 |
| Ruscalleda, J | 1 |
| Xu, G | 2 |
| Narr, KL | 1 |
| Woods, RP | 1 |
| Phillips, OR | 1 |
| Alger, JR | 1 |
| Espinoza, RT | 1 |
| Chen, X | 1 |
| Obergriesser, T | 1 |
| Ende, G | 1 |
| Braus, DF | 1 |
| Henn, FA | 1 |
| Kaufman, MJ | 1 |
| Henry, ME | 1 |
| Frederick, Bd | 1 |
| Hennen, J | 1 |
| Villafuerte, RA | 1 |
| Stoddard, EP | 1 |
| Schmidt, ME | 1 |
| Cohen, BM | 1 |
| Vythilingam, M | 1 |
| Charles, HC | 1 |
| Tupler, LA | 1 |
| Blitchington, T | 1 |
| Kelly, L | 1 |
| Krishnan, KR | 1 |
| Smith, EA | 1 |
| Lorch, E | 1 |
| Banerjee, SP | 2 |
| Rose, M | 2 |
| Ivey, J | 2 |
| Bhandari, R | 2 |
| Wood, SJ | 1 |
| Berger, G | 1 |
| Velakoulis, D | 1 |
| Phillips, LJ | 1 |
| McGorry, PD | 1 |
| Yung, AR | 1 |
| Desmond, P | 1 |
| Pantelis, C | 1 |
| Blasi, G | 1 |
| Bertolino, A | 1 |
| Brudaglio, F | 1 |
| Sciota, D | 1 |
| Altamura, M | 1 |
| Antonucci, N | 1 |
| Scarabino, T | 1 |
| Weinberger, DR | 1 |
| Nardini, M | 1 |
| Tang, J | 1 |
| Smith, JM | 1 |
| Boyd, C | 1 |
| Caetano, SC | 1 |
| Fonseca, M | 1 |
| Olvera, RL | 1 |
| Nicoletti, M | 1 |
| Hatch, JP | 1 |
| Stanley, JA | 1 |
| Hunter, K | 1 |
| Lafer, B | 1 |
| Pliszka, SR | 1 |
| Soares, JC | 1 |
| Coupland, NJ | 1 |
| Ogilvie, CJ | 1 |
| Hegadoren, KM | 1 |
| Seres, P | 1 |
| Hanstock, CC | 1 |
| Allen, PS | 1 |
| Yildiz-Yesiloglu, A | 1 |
| Ankerst, DP | 1 |
| Ajilore, O | 1 |
| Haroon, E | 1 |
| Kumaran, S | 1 |
| Darwin, C | 1 |
| Binesh, N | 1 |
| Mintz, J | 2 |
| Miller, J | 1 |
| Thomas, MA | 1 |
| Kumar, A | 2 |
| Holtzmann, J | 1 |
| Polosan, M | 1 |
| Baro, P | 1 |
| Bougerol, T | 1 |
| Hess, DA | 1 |
| Babb, JS | 1 |
| Klein, RG | 1 |
| Gonen, O | 1 |
| Fava, M | 1 |
| Rosenbaum, JF | 1 |
| Kolsky, AR | 1 |
| Alpert, JE | 1 |
| Nierenberg, AA | 1 |
| Spillmann, M | 1 |
| Moore, C | 1 |
| Renshaw, P | 1 |
| Bottiglieri, T | 1 |
| Moroz, G | 1 |
| Magni, G | 1 |
| Pütz, B | 1 |
| Kraft, E | 1 |
| Lipinski, B | 1 |
| Schill, J | 1 |
| Holsboer, F | 1 |
| Murata, T | 1 |
| Kimura, H | 1 |
| Omori, M | 1 |
| Kado, H | 1 |
| Kosaka, H | 1 |
| Iidaka, T | 1 |
| Itoh, H | 1 |
| Wada, Y | 1 |
| Kusumakar, V | 1 |
| Gates, L | 1 |
| Sparkes, SJ | 1 |
| Khan, SC | 1 |
| Thomas, A | 1 |
| Lavretsky, H | 1 |
| Yue, K | 1 |
| Huda, A | 1 |
| Curran, J | 1 |
| Venkatraman, T | 1 |
| Estanol, L | 1 |
| Mega, M | 1 |
| Toga, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Glycine Transport Inhibition on Brain Glycine Concentration[NCT00538070] | 68 participants (Actual) | Interventional | 2007-08-31 | Completed | |||
| Pharmacogenetics and Neuroimaging in Major Depressive Disorder (PAN-D)[NCT01568684] | Phase 1 | 0 participants (Actual) | Interventional | 2012-03-12 | Withdrawn | ||
| An Investigation of the Antidepressant Efficacy of Memantine, an NMDA Antagonist With Neurotrophic Properties in Major Depression[NCT00040261] | Phase 3 | 112 participants | Interventional | 2002-06-30 | Completed | ||
| An Investigation of the Antidepressant Efficacy of an Antiglutamatergic Agent in Bipolar Depression[NCT00054704] | Phase 2 | 19 participants (Actual) | Interventional | 2003-02-28 | Terminated (stopped due to Placebo was better than active drug.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Montgomery-Asberg Depression Rating Scale (MADRS) is a clinician-rated assessment of depression symptoms. Patients were rated weekly on 10 symptoms on a scale of 0 to 6 for each item, where 0 indicated no symptoms and 6 indicated the highest severity of that symptom. Total scores range from 0 to 60, where a moderate severity of depression would be present with a score of at least 20. (NCT00054704)
Timeframe: 8 weeks
| Intervention | Units on a scale (Least Squares Mean) |
|---|---|
| Riluzole | 29.551 |
| Placebo | 23.723 |
3 reviews available for choline and Depression, Involutional
| Article | Year |
|---|---|
Brain choline in major depression: A review of the literature.
Topics: Brain; Choline; Cross-Sectional Studies; Depressive Disorder, Major; Electroconvulsive Therapy; Huma | 2018 |
Review of 1H magnetic resonance spectroscopy findings in major depressive disorder: a meta-analysis.
Topics: Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; gamma-Aminobutyric Acid; Glutam | 2006 |
[ECT: from neuronal plasticity to mechanisms underlying antidepressant medication effect].
Topics: Antidepressive Agents; Aspartic Acid; Brain; Brain-Derived Neurotrophic Factor; Choline; Depressive | 2007 |
6 trials available for choline and Depression, Involutional
| Article | Year |
|---|---|
Anterior cingulate cortex and cerebellar hemisphere neurometabolite changes in depression treatment: A 1H magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Cerebellum; Choline; Depressive Disorder, M | 2014 |
The glutamatergic system and its relation to the clinical effect of therapeutic-sleep deprivation in depression - an MR spectroscopy study.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Choline; Creatine; Depressive Disorder, Ma | 2009 |
Glutamate normalization with ECT treatment response in major depression.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Depressive Disorder, Major; Electroconvulsive T | 2013 |
Hippocampal N-acetylaspartate and morning cortisol levels in drug-naive, first-episode patients with major depressive disorder: effects of treatment.
Topics: Adolescent; Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; De | 2012 |
Selective serotonin reuptake inhibitor discontinuation syndrome is associated with a rostral anterior cingulate choline metabolite decrease: a proton magnetic resonance spectroscopic imaging study.
Topics: Adult; Brain Mapping; Choline; Depressive Disorder, Major; Female; Fluoxetine; Gyrus Cinguli; Humans | 2003 |
Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients.
Topics: Adolescent; Child; Choline; Depressive Disorder, Major; Female; Glutamine; Humans; Inositol; Magneti | 2005 |
42 other studies available for choline and Depression, Involutional
| Article | Year |
|---|---|
Correlations between facial emotion processing and biochemical abnormalities in untreated adolescent patients with major depressive disorder: A proton magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Emotions; Humans; Prefront | 2022 |
Associations between executive function impairment and biochemical abnormalities in depressed adolescents with non-suicidal self-injury.
Topics: Adolescent; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Executive Function; Humans | 2022 |
Childhood trauma history is linked to abnormal brain metabolism of non-medicated adult patients with major depressive disorder.
Topics: Adult; Adverse Childhood Experiences; Aspartic Acid; Brain; Child, Preschool; Choline; Creatine; Cro | 2022 |
Cognitive dysfunction and neurometabolic alternations in major depressive disorder with gastrointestinal symptoms.
Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Depressive Disorder, Major; Humans; Proton | 2023 |
Plasma Neuronal and Glial Markers and Anterior Cingulate Metabolite Levels in Major Depressive Disorder: A Pilot Study.
Topics: Adult; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Gyrus Cinguli; Humans; | 2020 |
Altered neurometabolism in major depressive disorder: A whole brain
Topics: Adult; Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; Energy Metabolism; Femal | 2020 |
A Preliminary Nuclear Magnetic Resonance Metabolomics Study Identifies Metabolites that Could Serve as Diagnostic Markers of Major Depressive Disorder.
Topics: Acetone; Alanine; Biomarkers; Choline; Creatinine; Depressive Disorder, Major; Fatty Acids; Glutamin | 2022 |
A pilot study of cortical glutathione in youth with depression.
Topics: Adolescent; Anhedonia; Aspartic Acid; Case-Control Studies; Child; Choline; Creatine; Depression; De | 2017 |
Correlations between working memory impairment and neurometabolites of prefrontal cortex and lenticular nucleus in patients with major depressive disorder.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Corpus Striatum; Creatine; Depressive Disorder, | 2018 |
Elevated hippocampal choline level is associated with altered functional connectivity in females with major depressive disorder: A pilot study.
Topics: Adult; Brain; Brain Mapping; Choline; Depressive Disorder, Major; Female; Humans; Magnetic Resonance | 2018 |
Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Cost of Illness; Cross-Sectional Studies; Depre | 2013 |
Progressive decrease of N-acetylaspartate to total creatine ratio in the pregenual anterior cingulate cortex in patients with major depressive disorder: longitudinal 1H-MR spectroscopy study.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross-Sectiona | 2014 |
Anterior cingulate cortex choline levels in female adolescents with unipolar versus bipolar depression: a potential new tool for diagnosis.
Topics: Adolescent; Analysis of Variance; Bipolar Disorder; Choline; Creatine; Cross-Sectional Studies; Depr | 2014 |
Similarities of biochemical abnormalities between major depressive disorder and bipolar depression: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain; Choline; Creatine; Depressive Disorder, M | 2014 |
The correlation between biochemical abnormalities in frontal white matter, hippocampus and serum thyroid hormone levels in first-episode patients with major depressive disorder.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disorder, Major; Female; Hippoc | 2015 |
Increased ventricular cerebrospinal fluid lactate in depressed adolescents.
Topics: Adolescent; Aspartic Acid; Cerebral Ventricles; Cerebrospinal Fluid; Choline; Creatine; Depressive D | 2016 |
Proton spectroscopy study of the dorsolateral prefrontal cortex in youth with familial depression.
Topics: Adolescent; Adult; Choline; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Fe | 2016 |
Main Effects of Diagnoses, Brain Regions, and their Interaction Effects for Cerebral Metabolites in Bipolar and Unipolar Depressive Disorders.
Topics: Adult; Aspartic Acid; Biomarkers; Bipolar Disorder; Case-Control Studies; Choline; Creatine; Depress | 2016 |
Medial temporal N-acetyl-aspartate in pediatric major depression.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Humans; Mal | 2008 |
Proton MR spectroscopy of the hippocampus at 3 T in patients with unipolar major depressive disorder: correlates and predictors of treatment response.
Topics: Adult; Aspartic Acid; Case-Control Studies; Choline; Depressive Disorder, Major; Female; gamma-Amino | 2009 |
Biochemical abnormalities of the medial temporal lobe and medial prefrontal cortex in late-life depression.
Topics: Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Energy Metabolism; Functional Laterali | 2009 |
Proton magnetic resonance spectroscopy of late-life major depressive disorder.
Topics: Aged; Aging; Aspartic Acid; Basal Ganglia; Biomarkers; Brain; Choline; Cognition; Creatine; Depressi | 2009 |
Hippocampal metabolic abnormalities at first onset and with recurrent episodes of a major depressive disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Choline; Depressive Disorder, Major; Female; Glutamic Ac | 2009 |
Antidepressant effect detected on proton magnetic resonance spectroscopy in drug-naïve female patients with first-episode major depression.
Topics: Adult; Antidepressive Agents; Aspartic Acid; Case-Control Studies; Choline; Creatine; Depressive Dis | 2009 |
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition | 2010 |
Brain proton magnetic resonance spectroscopic study of insight among elders with late-life depression in remission.
Topics: Aged; Aspartic Acid; Awareness; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; | 2010 |
Ventromedial prefrontal spectroscopic abnormalities over the course of depression: a comparison among first episode, remitted recurrent and chronic patients.
Topics: Adult; Age of Onset; Aspartic Acid; Choline; Chronic Disease; Depressive Disorder, Major; Disease Pr | 2011 |
Frontal white matter biochemical abnormalities in first-episode, treatment-naive patients with major depressive disorder: a proton magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Diseases; Choline; Creatine; Depressive Dis | 2012 |
Long-term follow-up of magnetic resonance-detectable choline signal changes in the hippocampus of patients treated with electroconvulsive therapy.
Topics: Aspartic Acid; Choline; Cognition Disorders; Creatine; Depressive Disorder, Major; Electroconvulsive | 2003 |
Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: an automated multivoxel proton magnetic resonance spectroscopy study.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Choline; Creatine; Depressive Disorder, | 2003 |
Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study.
Topics: Adolescent; Analysis of Variance; Brain Chemistry; Brain Mapping; Case-Control Studies; Child; Choli | 2003 |
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Brain Mapping; Choline; Creatine; Depressive Dis | 2003 |
Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study.
Topics: Adolescent; Adult; Aspartic Acid; Bipolar Disorder; Cerebral Cortex; Choline; Creatine; Depressive D | 2004 |
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Ac | 2004 |
Decreased prefrontal Myo-inositol in major depressive disorder.
Topics: Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Case-Control Studies; Choline; Creatine; Depre | 2005 |
Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Chemistry; Choline; Creatine; Depressive Disord | 2007 |
Lateralized caudate metabolic abnormalities in adolescent major depressive disorder: a proton MR spectroscopy study.
Topics: Adolescent; Aspartic Acid; Caudate Nucleus; Choline; Cohort Studies; Creatine; Depressive Disorder, | 2007 |
Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder.
Topics: Adult; Benzophenones; Catechol O-Methyltransferase Inhibitors; Caudate Nucleus; Choline; Depressive | 1999 |
Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Glu | 2000 |
Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Glu | 2000 |
Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Glu | 2000 |
Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study.
Topics: Adult; Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Female; Frontal Lobe; Glu | 2000 |
MRI white matter hyperintensities, (1)H-MR spectroscopy and cognitive function in geriatric depression: a comparison of early- and late-onset cases.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Choline; Creatine; Depressive Disorder, Major; Energy | 2001 |
Left medial temporal cytosolic choline in early onset depression.
Topics: Adolescent; Amygdala; Aspartic Acid; Choline; Creatine; Cytosol; Depressive Disorder, Major; Dominan | 2001 |
Frontal white matter biochemical abnormalities in late-life major depression detected with proton magnetic resonance spectroscopy.
Topics: Aged; Aspartic Acid; Choline; Creatine; Depressive Disorder, Major; Dominance, Cerebral; Energy Meta | 2002 |