choline has been researched along with Demyelinating Diseases in 38 studies
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Citrulline was more frequently identified in the brains of patients with early-onset MS than in healthy subjects by (1)H-MR spectroscopy, suggesting an association of increased citrullination of myelin proteins with demyelinating diseases." | 5.14 | Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis. ( Aksu, AO; Anlar, B; Haspolat, S; Karabulut, E; Kurne, A; Kurul, S; Oguz, KK; Senbil, N; Serdaroglu, A; Teber, S, 2009) |
| "IM: Here we used a demyelination model using an injection of Lysophosphatidylcholine )LPC( in the corpus collosum to examine the myelination activity of differentiated oligodendrocytes derived from Human dental pulp stem cells )hDPDSCs( according to a two step induction protocol." | 1.62 | Recovery potential of transplanted oligoprogenitor cells derived from human dental pulp stem cells in Lysophosphatidyl choline demyelination mode. ( Bojnordi, MN; Ehsani, S; Hamidabadi, HG, 2021) |
| "Our results suggest that demyelination plays an important role in WM disruption post-injury in a subgroup of msTBI children and indicate the utility of multi-modal imaging." | 1.48 | Magnetic resonance spectroscopy of fiber tracts in children with traumatic brain injury: A combined MRS - Diffusion MRI study. ( Alger, J; Asarnow, RF; Babbitt, C; Babikian, T; Dennis, EL; Giza, CC; Jin, Y; Johnson, J; Mink, R; Olsen, A; Rashid, F; Thompson, PM; Villalon-Reina, JE, 2018) |
| "We are presenting two Leber's hereditary optic neuropathy (LHON) pedigrees with abnormal magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (H-MRS) findings but without neurological manifestation associated with LHON." | 1.43 | White Matter Changes in Two Leber's Hereditary Optic Neuropathy Pedigrees: 12-Year Follow-Up. ( Ćetković, M; Dejanović, I; Jančić, J; Kostić, V; Kozić, D; Ostojić, J; Radovanović, S; Samardžić, J; Đurić-Jovičić, M, 2016) |
| "After cuprizone-induced demyelination, CDP-choline effectively enhanced myelin regeneration and reversed motor coordination deficits." | 1.42 | Pivotal role of choline metabolites in remyelination. ( Baumgärtner, W; Degen, D; Gold, R; Gropengießer, K; Gudi, V; Hammer, A; Jörg, S; Lee, DH; Linker, RA; Manzel, A; Moharregh-Khiabani, D; Pul, R; Salinas Tejedor, L; Schäfer, N; Singh, V; Skripuletz, T; Stangel, M; Voss, E; Vulinovic, F; Wolf, R, 2015) |
| "Heroin could be a cause more common than thought of leukoencephalopathy." | 1.38 | [Toxic leucoencephalopathy after use of sniffed heroin, an unrecognized form of beneficial evolution]. ( Cotton, F; Drouet, A; Felten, D; Guilloton, L; Havé, L; Lamboley, JL; Quesnel, L; St-Pierre, G, 2012) |
| "Monofocal acute inflammatory demyelination (MAID), which is observable by CT and MRI as a well-enhanced mass lesion with prominent perifocal edema, is very similar to malignant gliomas radiologically, making differential diagnosis of the two pathologies difficult." | 1.37 | Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET. ( Aki, T; Asano, Y; Ito, T; Iwama, T; Miwa, K; Shinoda, J; Takenaka, S; Yokoyama, K, 2011) |
| "Tumefactive demyelination (TD) is a relatively uncommon entity which mimics other focal intracranial lesions." | 1.37 | Conventional and advanced magnetic resonance imaging in tumefactive demyelination. ( Chatterjee, S; Kesavadas, C; Saini, J; Thomas, B, 2011) |
| "Active demyelination or increased myelin turnover might contribute to the hitherto unexplained WMD of this rare disorder." | 1.33 | White-matter disease in 18q deletion (18q-) syndrome: magnetic resonance spectroscopy indicates demyelination or increased myelin turnover rather than dysmyelination. ( Anhuf, D; Häusler, M; Möller-Hartmann, W; Ramaekers, VT; Schüler, H; Thron, A; Zerres, K, 2005) |
| "They presented with congenital microcephaly, severe psychomotor retardation and intractable seizures." | 1.31 | Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency. ( de Koning, TJ; Jaeken, J; Pineda, M; Poll-The, BT; van der Knaap, MS; Van Maldergem, L, 2000) |
| "A Cho elevation may precede visible demyelination on T2-weighted images." | 1.30 | The value of new MRI techniques in adrenoleukodystrophy. ( Engelbrecht, V; Gärtner, J; Kahn, T; Mödder, U; Rassek, M, 1997) |
| "MR studies of these infants showed obstructive hydrocephalus caused by mass effect produced by an enlarged cerebellum." | 1.30 | Imaging studies in a unique familial dysmyelinating disorder. ( Duhaime, AC; Gripp, KW; Molloy, PT; Muenke, M; Rorke, LB; Schut, L; Tucker, SH; Wang, ZJ; Zackai, EH; Zimmerman, RA, 1998) |
| "The mechanisms behind the demyelination that is characteristic of multiple sclerosis (MS) are still poorly understood." | 1.30 | Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy. ( Bitsch, A; Brück, W; Bruhn, H; Frahm, J; Lassmann, H; Stringaris, A; Vougioukas, V, 1999) |
| "Despite regional variability of demyelination, proton magnetic resonance spectroscopy revealed a specific metabolic pattern in all patients, with only moderate reduction of N-acetylaspartate, normal or reduced choline-containing compounds, normal or enhanced myo-inositol and no detectable lactate, which differs from findings in progressive cerebral adrenoleukodystrophy which usually exhibits a severe reduction of N-acetylaspartate and marked increases of choline-containing compounds, myo-inositol, and lactate." | 1.29 | Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients. ( Frahm, J; Hanefeld, F; Hunneman, DH; Jost, W; Korenke, GC; Krasemann, E; Pouwels, PJ; Stoeckler, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 12 (31.58) | 29.6817 |
| 2010's | 14 (36.84) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Hamidabadi, HG | 1 |
| Bojnordi, MN | 1 |
| Ehsani, S | 1 |
| Dennis, EL | 1 |
| Babikian, T | 1 |
| Alger, J | 1 |
| Rashid, F | 1 |
| Villalon-Reina, JE | 1 |
| Jin, Y | 1 |
| Olsen, A | 1 |
| Mink, R | 1 |
| Babbitt, C | 1 |
| Johnson, J | 1 |
| Giza, CC | 1 |
| Thompson, PM | 1 |
| Asarnow, RF | 1 |
| Lu, SS | 1 |
| Kim, SJ | 1 |
| Kim, HS | 1 |
| Choi, CG | 1 |
| Lim, YM | 1 |
| Kim, EJ | 1 |
| Kim, DY | 1 |
| Cho, SH | 1 |
| Skripuletz, T | 2 |
| Manzel, A | 1 |
| Gropengießer, K | 1 |
| Schäfer, N | 1 |
| Gudi, V | 2 |
| Singh, V | 1 |
| Salinas Tejedor, L | 1 |
| Jörg, S | 1 |
| Hammer, A | 1 |
| Voss, E | 1 |
| Vulinovic, F | 1 |
| Degen, D | 1 |
| Wolf, R | 1 |
| Lee, DH | 1 |
| Pul, R | 1 |
| Moharregh-Khiabani, D | 1 |
| Baumgärtner, W | 2 |
| Gold, R | 1 |
| Linker, RA | 2 |
| Stangel, M | 2 |
| Praet, J | 1 |
| Orije, J | 1 |
| Kara, F | 1 |
| Guglielmetti, C | 1 |
| Santermans, E | 1 |
| Daans, J | 1 |
| Hens, N | 1 |
| Verhoye, M | 1 |
| Berneman, Z | 1 |
| Ponsaerts, P | 1 |
| Van der Linden, A | 1 |
| Grieb, P | 1 |
| Takanashi, J | 1 |
| Jančić, J | 1 |
| Dejanović, I | 1 |
| Radovanović, S | 1 |
| Ostojić, J | 1 |
| Kozić, D | 1 |
| Đurić-Jovičić, M | 1 |
| Samardžić, J | 1 |
| Ćetković, M | 1 |
| Kostić, V | 1 |
| Oguz, KK | 1 |
| Kurne, A | 1 |
| Aksu, AO | 1 |
| Karabulut, E | 1 |
| Serdaroglu, A | 1 |
| Teber, S | 1 |
| Haspolat, S | 1 |
| Senbil, N | 1 |
| Kurul, S | 1 |
| Anlar, B | 1 |
| Machado, A | 1 |
| Soares-Fernandes, J | 1 |
| Ribeiro, M | 1 |
| Rodrigues, M | 1 |
| Cerqueira, J | 1 |
| Ferreira, C | 1 |
| Kato, Z | 1 |
| Morimoto, M | 1 |
| Orii, KE | 1 |
| Kato, T | 1 |
| Kondo, N | 1 |
| Beppu, T | 1 |
| Nishimoto, H | 1 |
| Fujiwara, S | 1 |
| Kudo, K | 1 |
| Sanjo, K | 1 |
| Narumi, S | 1 |
| Oikawa, H | 1 |
| Onodera, M | 1 |
| Ogasawara, K | 1 |
| Sasaki, M | 1 |
| Takenaka, S | 1 |
| Shinoda, J | 1 |
| Asano, Y | 1 |
| Aki, T | 1 |
| Miwa, K | 1 |
| Ito, T | 1 |
| Yokoyama, K | 1 |
| Iwama, T | 1 |
| Havé, L | 1 |
| Drouet, A | 1 |
| Lamboley, JL | 1 |
| Cotton, F | 1 |
| St-Pierre, G | 1 |
| Quesnel, L | 1 |
| Guilloton, L | 1 |
| Felten, D | 1 |
| Saini, J | 1 |
| Chatterjee, S | 1 |
| Thomas, B | 1 |
| Kesavadas, C | 1 |
| Rajasekharan, C | 1 |
| Anto, V | 1 |
| Unnikrishnan, R | 1 |
| Gambini, A | 1 |
| Falini, A | 1 |
| Moiola, L | 1 |
| Comi, G | 1 |
| Scotti, G | 1 |
| Tarasów, E | 1 |
| Wiercińska-Drapało, A | 1 |
| Walecki, J | 1 |
| Prokopowicz, D | 1 |
| Kwee, SA | 1 |
| Coel, MN | 1 |
| Lim, J | 1 |
| Ko, JP | 1 |
| Häusler, M | 1 |
| Anhuf, D | 1 |
| Schüler, H | 1 |
| Ramaekers, VT | 1 |
| Thron, A | 1 |
| Zerres, K | 1 |
| Möller-Hartmann, W | 1 |
| Porto, L | 1 |
| Hattingen, E | 1 |
| Pilatus, U | 1 |
| Kieslich, M | 1 |
| Yan, B | 1 |
| Schwabe, D | 1 |
| Zanella, FE | 1 |
| Lanfermann, H | 1 |
| Cianfoni, A | 1 |
| Niku, S | 1 |
| Imbesi, SG | 1 |
| Hiehle, JF | 1 |
| Lenkinski, RE | 2 |
| Grossman, RI | 2 |
| Dousset, V | 1 |
| Ramer, KN | 1 |
| Schnall, MD | 1 |
| Cohen, JA | 1 |
| Gonzalez-Scarano, F | 2 |
| Hájek, M | 1 |
| Hejcmanová, L | 1 |
| Prádný, J | 1 |
| De Stefano, N | 1 |
| Matthews, PM | 2 |
| Antel, JP | 2 |
| Preul, M | 1 |
| Francis, G | 1 |
| Arnold, DL | 2 |
| Kimura, H | 1 |
| Korenke, GC | 1 |
| Pouwels, PJ | 2 |
| Frahm, J | 2 |
| Hunneman, DH | 1 |
| Stoeckler, S | 1 |
| Krasemann, E | 1 |
| Jost, W | 1 |
| Hanefeld, F | 1 |
| Engelbrecht, V | 1 |
| Rassek, M | 1 |
| Gärtner, J | 1 |
| Kahn, T | 1 |
| Mödder, U | 1 |
| Gripp, KW | 1 |
| Zimmerman, RA | 2 |
| Wang, ZJ | 1 |
| Rorke, LB | 1 |
| Duhaime, AC | 1 |
| Schut, L | 1 |
| Molloy, PT | 1 |
| Tucker, SH | 1 |
| Zackai, EH | 1 |
| Muenke, M | 1 |
| Bitsch, A | 1 |
| Bruhn, H | 1 |
| Vougioukas, V | 1 |
| Stringaris, A | 1 |
| Lassmann, H | 1 |
| Brück, W | 1 |
| van der Knaap, MS | 2 |
| Wevers, RA | 1 |
| Struys, EA | 1 |
| Verhoeven, NM | 1 |
| Engelke, UF | 1 |
| Feikema, W | 1 |
| Valk, J | 1 |
| Jakobs, C | 1 |
| Izquierdo, M | 1 |
| Adamsbaum, C | 1 |
| Benosman, A | 1 |
| Aubourg, P | 1 |
| Bittoun, J | 1 |
| Pozdniakov, AV | 1 |
| Tiutin, LA | 1 |
| Bisaga, GN | 1 |
| Odinak, MM | 1 |
| de Koning, TJ | 1 |
| Jaeken, J | 1 |
| Pineda, M | 1 |
| Van Maldergem, L | 1 |
| Poll-The, BT | 1 |
| Espay, AJ | 1 |
| Bodensteiner, JB | 1 |
| Patel, H | 1 |
| Francis, GS | 1 |
| O'Connor, J | 1 |
| Marks, HG | 1 |
| Caro, PA | 1 |
| Wang, ZY | 1 |
| Detre, JA | 1 |
| Bogdan, AR | 1 |
| Gusnard, DA | 1 |
1 review available for choline and Demyelinating Diseases
| Article | Year |
|---|---|
Neurochemistry of Hypomyelination Investigated with MR Spectroscopy.
Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Demyelinating Diseases; Disease Models, | 2015 |
1 trial available for choline and Demyelinating Diseases
| Article | Year |
|---|---|
Assessment of citrullinated myelin by 1H-MR spectroscopy in early-onset multiple sclerosis.
Topics: Adolescent; Age of Onset; Aspartic Acid; Child; Child, Preschool; Choline; Citrulline; Creatine; Dem | 2009 |
36 other studies available for choline and Demyelinating Diseases
| Article | Year |
|---|---|
Recovery potential of transplanted oligoprogenitor cells derived from human dental pulp stem cells in Lysophosphatidyl choline demyelination mode.
Topics: Animals; Choline; Demyelinating Diseases; Dental Pulp; Humans; Lysophosphatidylcholines; Mesenchymal | 2021 |
Magnetic resonance spectroscopy of fiber tracts in children with traumatic brain injury: A combined MRS - Diffusion MRI study.
Topics: Adolescent; Anisotropy; Aspartic Acid; Brain Damage, Chronic; Brain Injuries, Traumatic; Child; Chol | 2018 |
Utility of proton MR spectroscopy for differentiating typical and atypical primary central nervous system lymphomas from tumefactive demyelinating lesions.
Topics: Aspartic Acid; Biomarkers; Brain Neoplasms; Choline; Demyelinating Diseases; Diagnosis, Differential | 2014 |
Pivotal role of choline metabolites in remyelination.
Topics: Animals; Cell Proliferation; Chelating Agents; Choline; Cuprizone; Cytidine Diphosphate Choline; Dem | 2015 |
Cuprizone-induced demyelination and demyelination-associated inflammation result in different proton magnetic resonance metabolite spectra.
Topics: Animals; Aspartic Acid; Brain Chemistry; Choline; Creatine; Cuprizone; Demyelinating Diseases; Dipep | 2015 |
Beneficial effects of exogenous CDP-choline (citicoline) in EAE.
Topics: Animals; Choline; Demyelinating Diseases; Myelin Sheath | 2015 |
Reply: Beneficial effects of exogenous CDP-choline (citicoline) in EAE.
Topics: Animals; Choline; Demyelinating Diseases; Myelin Sheath | 2015 |
White Matter Changes in Two Leber's Hereditary Optic Neuropathy Pedigrees: 12-Year Follow-Up.
Topics: Adult; Aged; Choline; Creatinine; Demyelinating Diseases; DNA, Mitochondrial; Female; Glucocorticoid | 2016 |
Alcohol abuse and acute behavioural disturbances in a 24-year-old patient. Diagnosis: Marchiafava-Bignami disease (MBD).
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Aspartic Acid; Choline; Corpus Callosum; Crea | 2009 |
Developmental changes of radiological findings in Fukuyama-type congenital muscular dystrophy.
Topics: Biomarkers; Choline; Creatine; Demyelinating Diseases; Humans; Infant; Magnetic Resonance Imaging; M | 2010 |
1H-magnetic resonance spectroscopy indicates damage to cerebral white matter in the subacute phase after CO poisoning.
Topics: Brain; Brain Diseases, Metabolic; Carbon Monoxide Poisoning; Choline; Creatine; Demyelinating Diseas | 2011 |
Metabolic assessment of monofocal acute inflammatory demyelination using MR spectroscopy and (11)C-methionine-, (11)C-choline-, and (18)F-fluorodeoxyglucose-PET.
Topics: Brain Neoplasms; Carbon Radioisotopes; Choline; Creatine; Demyelinating Diseases; Diagnosis, Differe | 2011 |
[Toxic leucoencephalopathy after use of sniffed heroin, an unrecognized form of beneficial evolution].
Topics: Administration, Inhalation; Biopsy; Brain Chemistry; Brain Edema; Choline; Cognition Disorders; Demy | 2012 |
Conventional and advanced magnetic resonance imaging in tumefactive demyelination.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Mapping; Child; Choline; Contrast Media; Demyelinatin | 2011 |
Tumefactive demyelination-to cracks the nut without cracking the pot.
Topics: Choline; Corpus Callosum; Demyelinating Diseases; Diagnosis, Differential; Female; Glucocorticoids; | 2012 |
Marchiafava-Bignami disease: longitudinal MR imaging and MR spectroscopy study.
Topics: Alcohol-Related Disorders; Atrophy; Choline; Corpus Callosum; Creatine; Demyelinating Diseases; Huma | 2003 |
[CNS changes in HIV-infected patients: magnetic resonance spectroscopy].
Topics: AIDS Dementia Complex; Brain; Choline; Demyelinating Diseases; HIV Seropositivity; Humans; Inositol; | 2003 |
Combined use of F-18 fluorocholine positron emission tomography and magnetic resonance spectroscopy for brain tumor evaluation.
Topics: Adult; Brain; Brain Neoplasms; Choline; Demyelinating Diseases; Female; Fluorine Radioisotopes; Glio | 2004 |
White-matter disease in 18q deletion (18q-) syndrome: magnetic resonance spectroscopy indicates demyelination or increased myelin turnover rather than dysmyelination.
Topics: Aspartic Acid; Brain Diseases; Choline; Chromosome Deletion; Chromosomes, Human, Pair 18; Demyelinat | 2005 |
Proton magnetic resonance spectroscopy in childhood brainstem lesions.
Topics: Adolescent; Amino Acids; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Stem; Brain Stem Neop | 2007 |
Metabolite findings in tumefactive demyelinating lesions utilizing short echo time proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Neoplasms; Choline; Creatine; Demyelinating Diseases; | 2007 |
Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Choline; Cohort Studies; Creatine; Demyelinating Dise | 1994 |
Proton in vivo spectroscopy of patients with hyperphenylalaninaemia.
Topics: Adult; Aspartic Acid; Biopterins; Brain; Brain Chemistry; Brain Diseases; Child; Choline; Creatine; | 1993 |
Chemical pathology of acute demyelinating lesions and its correlation with disability.
Topics: Adult; Aspartic Acid; Brain Chemistry; Choline; Demyelinating Diseases; Disability Evaluation; Femal | 1995 |
Proton MR spectroscopy and magnetization transfer ratio in multiple sclerosis: correlative findings of active versus irreversible plaque disease.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases; Brain Edema; Choline; Chronic Disease; Creatine; Demyel | 1996 |
Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Child; Choline; Demyelinating Diseases; Female; Hum | 1996 |
The value of new MRI techniques in adrenoleukodystrophy.
Topics: Adolescent; Adrenoleukodystrophy; Aspartic Acid; Brain; Child; Child, Preschool; Choline; Demyelinat | 1997 |
Imaging studies in a unique familial dysmyelinating disorder.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Canavan Disease; Cerebellar Diseases; Cerebral Cortex; Chol | 1998 |
Inflammatory CNS demyelination: histopathologic correlation with in vivo quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Axons; Biopsy, Needle; Blood-Brain Barrier; Brain; Cell Division; Choline; Dem | 1999 |
Leukoencephalopathy associated with a disturbance in the metabolism of polyols.
Topics: Adolescent; Aspartic Acid; Carbohydrate Metabolism, Inborn Errors; Choline; Creatine; Demyelinating | 1999 |
MR spectroscopic imaging of normal-appearing white matter in adrenoleukodystrophy.
Topics: Adolescent; Adrenoleukodystrophy; Adult; Age Factors; Brain; Child; Choline; Data Interpretation, St | 2000 |
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am | 2001 |
Hypomyelination and reversible white matter attenuation in 3-phosphoglycerate dehydrogenase deficiency.
Topics: Amino Acids; Carbohydrate Dehydrogenases; Cerebral Cortex; Child; Child, Preschool; Choline; Demyeli | 2000 |
Episodic coma in a new leukodystrophy.
Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post | 2002 |
Proton magnetic resonance spectroscopic imaging for metabolic characterization of demyelinating plaques.
Topics: Acute Disease; Adult; Aspartic Acid; Biopsy; Brain Chemistry; Brain Neoplasms; Choline; Creatine; De | 1992 |
Use of computed tomography, magnetic resonance imaging, and localized 1H magnetic resonance spectroscopy in Canavan's disease: a case report.
Topics: Amidohydrolases; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases, Metabolic; Chi | 1991 |