Page last updated: 2024-10-16

choline and Coronary Disease

choline has been researched along with Coronary Disease in 27 studies

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Among our African-American participants, higher dietary choline intake was associated with a lower risk of incident ischemic stroke, and thus putative dietary benefits."7.88Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study. ( Bidulescu, A; Dibaba, DT; Millard, HR; Musani, SK; Talegawkar, SA; Taylor, HA; Tucker, KL, 2018)
"Low dietary intake of the essential nutrient choline and its metabolite betaine may increase atherogenesis both through effects on homocysteine methylation pathways as well as through choline's antioxidants properties."7.74Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. ( Bidulescu, A; Chambless, LE; Heiss, G; Siega-Riz, AM; Zeisel, SH, 2007)
"Among our African-American participants, higher dietary choline intake was associated with a lower risk of incident ischemic stroke, and thus putative dietary benefits."3.88Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study. ( Bidulescu, A; Dibaba, DT; Millard, HR; Musani, SK; Talegawkar, SA; Taylor, HA; Tucker, KL, 2018)
"Low dietary intake of the essential nutrient choline and its metabolite betaine may increase atherogenesis both through effects on homocysteine methylation pathways as well as through choline's antioxidants properties."3.74Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. ( Bidulescu, A; Chambless, LE; Heiss, G; Siega-Riz, AM; Zeisel, SH, 2007)
"We found that choline relieved myocardial injuries during ischemia or under oxidative stress, which was achieved by correcting hemodynamic impairment, diminishing ventricular arrhythmias and protecting cardiomyocytes from apoptotic death."3.73Choline produces cytoprotective effects against ischemic myocardial injuries: evidence for the role of cardiac m3 subtype muscarinic acetylcholine receptors. ( Han, H; Lin, H; Liu, Y; Wang, H; Wang, Z; Xu, C; Yang, B, 2005)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's1 (3.70)18.2507
2000's6 (22.22)29.6817
2010's3 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagata, C1
Wada, K1
Tamura, T1
Konishi, K1
Kawachi, T1
Tsuji, M1
Nakamura, K1
Mueller, DM1
Allenspach, M1
Othman, A1
Saely, CH1
Muendlein, A1
Vonbank, A1
Drexel, H1
von Eckardstein, A1
Millard, HR1
Musani, SK1
Dibaba, DT1
Talegawkar, SA1
Taylor, HA1
Tucker, KL1
Bidulescu, A2
GREENBERG, SU1
BRUGER, M1
SELLERS, EA1
YOU, RW1
SAVENKOV, PM1
FAUDA, C1
GRIGOLATO, V1
CANDIANI, C1
VALERIO, VM1
FROLLO, A1
GELPKE, H1
TAKENAKA, F1
RENAUD, S1
ALLARD, C1
SINITSINA, TA1
Lindman, AS1
Pedersen, JI1
Arnesen, H1
Hjerkinn, EM1
Veierød, MB1
Prydz, H1
Seljeflot, I1
Apple, FS1
Wu, AH1
Mair, J1
Ravkilde, J1
Panteghini, M1
Tate, J1
Pagani, F1
Christenson, RH1
Mockel, M3
Danne, O3
Jaffe, AS1
Lueders, C2
Storm, C2
Frei, U2
Yang, B1
Lin, H1
Xu, C1
Liu, Y1
Wang, H1
Han, H1
Wang, Z1
Chambless, LE1
Siega-Riz, AM1
Zeisel, SH1
Heiss, G1
Bykov, II1
Beliakov, KF2
Slobodin, AK1
Zhivoderov, VM1
Knyzhov, VV1
Lown, B1
Olszewski, AJ2
Lochner, A1
de Villiers, M1
Szostak, WB1
Bialkowska, M1
Rudnicki, S1
McCully, KS1
Vittori, C1
Borri, P1
Bianchi, V1
Clower, BR1
Carrier, O1
Ball, CR1
Dobrowolski, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)[NCT02016430]150 participants (Anticipated)Interventional2014-04-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for choline and Coronary Disease

ArticleYear
Future biomarkers for detection of ischemia and risk stratification in acute coronary syndrome.
    Clinical chemistry, 2005, Volume: 51, Issue:5

    Topics: Acute Disease; Albumins; Biomarkers; CD40 Ligand; Chest Pain; Choline; Coronary Disease; Diagnosis,

2005

Other Studies

26 other studies available for choline and Coronary Disease

ArticleYear
Choline and Betaine Intakes Are Not Associated with Cardiovascular Disease Mortality Risk in Japanese Men and Women.
    The Journal of nutrition, 2015, Volume: 145, Issue:8

    Topics: Adult; Animals; Asian People; Betaine; Choline; Coronary Disease; Diet; Female; Humans; Male; Middle

2015
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
    Atherosclerosis, 2015, Volume: 243, Issue:2

    Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Cor

2015
Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study.
    European journal of nutrition, 2018, Volume: 57, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Betaine; Black People; Cardiovascular Diseases; Choline; Coronary Di

2018
Failure of choline therapy to alter serum lipids in patients with coronary artery disease.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 84, Issue:1

    Topics: Anti-Arrhythmia Agents; Blood; Cardiotonic Agents; Choline; Coronary Artery Disease; Coronary Diseas

1953
Deposition of fat in coronary arteries after exposure to cold.
    British medical journal, 1956, Apr-14, Volume: 1, Issue:4971

    Topics: Cholesterol; Choline; Cold Temperature; Coronary Disease; Coronary Vessels; Diet; Fats; Humans; Lipi

1956
[The use of choline in coronary atherosclerosis].
    Sovetskaia meditsina, 1957, Volume: 21, Issue:8

    Topics: Anti-Arrhythmia Agents; Cardiotonic Agents; Choline; Coronary Artery Disease; Coronary Disease; Glyc

1957
[Association of coronarodilatory & cardiotrophic drugs in the treatment of coronary insufficiency].
    Minerva medica, 1959, Mar-17, Volume: 50, Issue:22

    Topics: Anti-Arrhythmia Agents; Choline; Coronary Artery Disease; Coronary Disease; Enzyme Inhibitors; Human

1959
[Clinical observations on the therapeutic use of choline theophyllinate].
    Gazzetta medica italiana, 1959, Volume: 118

    Topics: Choline; Coronary Disease; Heart Failure; Humans; Hypertension; Theophylline

1959
[Contribution to diagnosis and therapy of coronary disease].
    Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20

    Topics: Calcium; Choline; Coronary Disease; Humans; Methionine; Nucleotides

1963
[PHARMACOLOGICAL STUDIES ON ATHEROSCLEROSIS AND CORONARY CIRCULATION].
    Kumamoto Igakkai zasshi. The Journal of the Kumamoto Medical Society, 1963, Jan-25, Volume: 37

    Topics: Acetylcholine; Animals; Arteriosclerosis; Atherosclerosis; Blood Chemical Analysis; Blood Proteins;

1963
DIETARY FATS, VITAMINS AND BILE ACIDS IN THE PRODUCTION OF THROMBOSIS AND HYPERLIPEMIA IN RATS.
    Revue canadienne de biologie, 1963, Volume: 22

    Topics: Bile Acids and Salts; Blood Chemical Analysis; Butter; Cholesterol; Choline; Coronary Disease; Dieta

1963
[Effect of choline and thyroxin on recurrent development of coronary atherosclerosis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1955, Volume: 39, Issue:2

    Topics: Arteriosclerosis; Choline; Coronary Artery Disease; Coronary Disease; Humans; Thyroxine

1955
Coagulation factor VII, R353Q polymorphism, and serum choline-containing phospholipids in males at high risk for coronary heart disease.
    Thrombosis research, 2004, Volume: 113, Issue:1

    Topics: Aged; Choline; Comorbidity; Coronary Disease; Diabetes Mellitus; Factor VII; Follow-Up Studies; Geno

2004
Whole-blood hypercholinemia and coronary instability and thrombosis.
    Clinical chemistry, 2005, Volume: 51, Issue:7

    Topics: Aged; Biomarkers; Chest Pain; Choline; Chromatography, High Pressure Liquid; Coronary Disease; Coron

2005
Choline produces cytoprotective effects against ischemic myocardial injuries: evidence for the role of cardiac m3 subtype muscarinic acetylcholine receptors.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2005, Volume: 16, Issue:4-6

    Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Choline; Coronary Disease; Cytop

2005
Whole blood choline and plasma choline in acute coronary syndromes: prognostic and pathophysiological implications.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 383, Issue:1-2

    Topics: Aged; Choline; Chromatography, High Pressure Liquid; Coronary Artery Disease; Coronary Disease; Fema

2007
Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study.
    BMC cardiovascular disorders, 2007, Jul-13, Volume: 7

    Topics: Atherosclerosis; Betaine; Choline; Coronary Disease; Diet; Female; Follow-Up Studies; Humans; Incide

2007
[Presystolic change in the length of the ischemic, border and distant myocardial areas in experimental coronary insufficiency and the action of inderal and metacin].
    Kardiologiia, 1979, Volume: 19, Issue:4

    Topics: Acute Disease; Animals; Benzilates; Choline; Coronary Disease; Diastole; Dogs; Drug Evaluation, Prec

1979
[Functional heterogeneity of the myocardium and its significance in the processes of compensation of cardiac activity in different hemodynamic disorders].
    Kardiologiia, 1977, Volume: 17, Issue:6

    Topics: Animals; Aorta, Thoracic; Aortic Coarctation; Benzilates; Choline; Coronary Circulation; Coronary Di

1977
New concepts and approaches to sudden cardiac death.
    Schweizerische medizinische Wochenschrift, 1976, Nov-06, Volume: 106, Issue:45

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atropine; Autonomic Nervous System; Choline; Coronary

1976
Homocysteine content of plasma in ischemic heart disease, the reducing effect of pyridoxine, folate, cobalamin, choline, riboflavin and troxerutin. Correction of a calculation error.
    Atherosclerosis, 1991, Volume: 88, Issue:1

    Topics: Amino Acids; Anticoagulants; Choline; Coronary Disease; Folic Acid; Homocysteine; Humans; Hydroxyeth

1991
Phosphatidylcholine biosynthesis in myocardial ischaemia.
    Journal of molecular and cellular cardiology, 1989, Volume: 21, Issue:2

    Topics: Adenosine Triphosphate; Animals; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Co

1989
Reduction of plasma lipid and homocysteine levels by pyridoxine, folate, cobalamin, choline, riboflavin, and troxerutin in atherosclerosis.
    Atherosclerosis, 1989, Volume: 75, Issue:1

    Topics: Adult; Anticoagulants; Choline; Coronary Artery Disease; Coronary Disease; Drug Therapy, Combination

1989
[On the comparative results of the use of Clarisco in peripheral vascular diseases].
    Minerva medica, 1970, Dec-05, Issue:97 Suppl

    Topics: Aged; Arteriosclerosis Obliterans; Choline; Coronary Disease; Folic Acid; Gangrene; Heparin; Humans;

1970
The protective action of reserpine against diet-induced atrial thrombosis.
    European journal of pharmacology, 1967, Volume: 2, Issue:2

    Topics: Animals; Choline; Coronary Disease; Dietary Fats; Dietary Proteins; Female; Heart Atria; Heart Disea

1967
A contribution to the prophilaxis of coronary heart insufficiency in advanced age.
    Giornale di gerontologia, 1966, Volume: 14, Issue:10

    Topics: Aged; Alkenes; Choline; Coronary Disease; Humans; Phospholipids

1966