Page last updated: 2024-10-17

choline and Complications, Pregnancy

choline has been researched along with Complications, Pregnancy in 21 studies

Research Excerpts

ExcerptRelevanceReference
"Adequate choline intake during pregnancy is essential for proper fetal development."8.91[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy]. ( Drews, K, 2015)
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."7.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
" Experimental evidence obtained in rats suggest that the precipitous fall in maternal liver choline concentration nearing the end of pregnancy could lead to a severe reduction in the lipotropic activity of the liver."7.66Can tetracycline-induced fatty liver in pregnancy be attributed to choline deficiency? ( Gwee, MC, 1982)
"Lithium treatment can affect the transport of choline and lithium ions across cell membranes, but little is known about these effects during pregnancy."7.66Lithium treatment during pregnancy: a case study of erythrocyte choline content and lithium transport. ( Erstling, C; Hanin, I; Kopp, U; Mallinger, AG; Mallinger, J; Stumpf, RL, 1983)
"Adequate choline intake during pregnancy is essential for proper fetal development."4.91[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy]. ( Drews, K, 2015)
"Pregnancy and lactation are periods when maternal reserves of choline are depleted."4.79Choline: essential for brain development and function. ( Zeisel, SH, 1997)
"Maternal infection, depression, obesity, and other factors associated with inflammation were assessed at 16 weeks gestation, along with maternal C-reactive protein (CRP), cytokines, and serum choline."4.02Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development. ( D'Alessandro, A; Freedman, R; Hoffman, MC; Hunter, SK; Law, AJ; Noonan, K; Wyrwa, A, 2021)
"This study suggests that higher maternal plasma choline status during pregnancy is associated with more symptoms of antenatal depression and anxiety, whereas plasma betaine concentrations showed no associations."3.85Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort. ( Chen, H; Chong, MF; Chong, YS; Godfrey, KM; Meaney, MJ; Quah, PL; Saw, SM; van Lee, L; Yap, FKP, 2017)
" Experimental evidence obtained in rats suggest that the precipitous fall in maternal liver choline concentration nearing the end of pregnancy could lead to a severe reduction in the lipotropic activity of the liver."3.66Can tetracycline-induced fatty liver in pregnancy be attributed to choline deficiency? ( Gwee, MC, 1982)
"Lithium treatment can affect the transport of choline and lithium ions across cell membranes, but little is known about these effects during pregnancy."3.66Lithium treatment during pregnancy: a case study of erythrocyte choline content and lithium transport. ( Erstling, C; Hanin, I; Kopp, U; Mallinger, AG; Mallinger, J; Stumpf, RL, 1983)
"Choline is a dietary component essential for normal function of all cells."2.41Choline: needed for normal development of memory. ( Zeisel, SH, 2000)
"Birth weight was higher in the G allele homozygotes of the CHDH rs2289205 than in the minor allele carriers: GG: 3398 ± 64 g; GA+AA: 3193 ± 76 g."1.48PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women. ( Barlik, M; Chmurzynska, A; Drews, K; Jagodziński, PP; Kurzawińska, G; Malinowska, AM; Radziejewska, A; Różycka, A; Seremak-Mrozikiewicz, A; Szwengiel, A, 2018)
"Choline is an essential nutrient for animals and humans."1.32Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. ( Blusztajn, JK; Meck, WH; Mellott, TJ; Williams, CL, 2004)
"Two cases of reversible posterior leukoencephalopathy syndrome were examined with proton MR spectroscopic imaging."1.31Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome. ( Barker, PB; Beauchamp, NJ; Eichler, FS; Wang, P; Wityk, RJ, 2002)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's1 (4.76)18.2507
2000's6 (28.57)29.6817
2010's7 (33.33)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Hunter, SK1
Hoffman, MC1
D'Alessandro, A1
Noonan, K1
Wyrwa, A1
Freedman, R1
Law, AJ1
van Lee, L1
Quah, PL1
Saw, SM1
Yap, FKP1
Godfrey, KM1
Chong, YS1
Meaney, MJ1
Chen, H1
Chong, MF1
Nam, J1
Greenwald, E1
Jack-Roberts, C1
Ajeeb, TT1
Malysheva, OV2
Caudill, MA2
Axen, K1
Saxena, A1
Semernina, E1
Nanobashvili, K1
Jiang, X2
Chmurzynska, A1
Seremak-Mrozikiewicz, A1
Malinowska, AM1
Różycka, A1
Radziejewska, A1
Szwengiel, A1
Kurzawińska, G1
Barlik, M1
Jagodziński, PP1
Drews, K2
Christensen, KE1
Deng, L1
Leung, KY1
Arning, E1
Bottiglieri, T1
Krupenko, NI1
Greene, ND1
Jerome-Majewska, L1
MacKenzie, RE1
Rozen, R2
Wang, Y1
Surzenko, N1
Friday, WB1
Zeisel, SH3
Mikael, LG1
Pancer, J1
Wu, Q1
Caudill, M1
DIAMOND, CA1
MOORE, HC1
Mellott, TJ1
Williams, CL1
Meck, WH1
Blusztajn, JK1
da Silva, LF1
Höefel Filho, JR1
Anés, M1
Nunes, ML1
Maloney, CA1
Hay, SM1
Rees, WD1
Gwee, MC1
Mallinger, AG1
Hanin, I1
Stumpf, RL1
Mallinger, J1
Kopp, U1
Erstling, C1
Kinney, DK1
Steingard, RJ1
Renshaw, PF1
Yurgelun-Todd, DA1
Eichler, FS1
Wang, P1
Wityk, RJ1
Beauchamp, NJ1
Barker, PB1
Kratzing, CC1
Perry, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Choline Supplementation on Fetal Growth in Gestational Diabetes Mellitus[NCT04302168]60 participants (Anticipated)Interventional2020-04-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for choline and Complications, Pregnancy

ArticleYear
[Folate metabolism--epigenetic role of choline and vitamin B12 during pregnancy].
    Ginekologia polska, 2015, Volume: 86, Issue:12

    Topics: Choline; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Humans; Maternal Nutritiona

2015
Choline: essential for brain development and function.
    Advances in pediatrics, 1997, Volume: 44

    Topics: Acetylcholine; Animals; Apoptosis; Brain; Choline; Choline Deficiency; Female; Humans; Infant, Newbo

1997
Choline: needed for normal development of memory.
    Journal of the American College of Nutrition, 2000, Volume: 19, Issue:5 Suppl

    Topics: Animals; Brain; Choline; Choline Deficiency; Diet; Eggs; Female; Humans; Infant, Newborn; Lactation;

2000
Lipotropes and fetal growth.
    Nutrition reviews, 1971, Volume: 29, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Choline; Cystine; Deficiency

1971

Trials

1 trial available for choline and Complications, Pregnancy

ArticleYear
Prognostic value of 1H-MRS in neonatal encephalopathy.
    Pediatric neurology, 2006, Volume: 34, Issue:5

    Topics: Apgar Score; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Choline; Creatine; Creatinine; Femal

2006

Other Studies

16 other studies available for choline and Complications, Pregnancy

ArticleYear
Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development.
    Psychological medicine, 2021, Volume: 51, Issue:3

    Topics: Brain; C-Reactive Protein; Choline; Female; Fetal Development; Fetus; Gestational Age; Humans; Infan

2021
Maternal choline status during pregnancy, but not that of betaine, is related to antenatal mental well-being: The growing up in Singapore toward healthy outcomes cohort.
    Depression and anxiety, 2017, Volume: 34, Issue:10

    Topics: Adult; Anxiety; Betaine; Choline; Cohort Studies; Depression; Female; Humans; Personal Satisfaction;

2017
Choline prevents fetal overgrowth and normalizes placental fatty acid and glucose metabolism in a mouse model of maternal obesity.
    The Journal of nutritional biochemistry, 2017, Volume: 49

    Topics: Animals; Biomarkers; Choline; Diet, High-Fat; Dietary Supplements; Fatty Acid Transport Proteins; Fe

2017
PEMT rs12325817 and PCYT1A rs7639752 polymorphisms are associated with betaine but not choline concentrations in pregnant women.
    Nutrition research (New York, N.Y.), 2018, Volume: 56

    Topics: Adolescent; Adult; Alleles; Betaine; Birth Weight; Carnitine; Choline; Choline-Phosphate Cytidylyltr

2018
A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
    Human molecular genetics, 2013, Sep-15, Volume: 22, Issue:18

    Topics: Aminohydrolases; Animals; Cell Proliferation; Cells, Cultured; Choline; Congenital Abnormalities; Em

2013
Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:4

    Topics: Animals; Blotting, Western; Cell Count; Cells, Cultured; Cerebral Cortex; Choline; Choline Deficienc

2016
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homo

2013
Hemoglobin synthesis with iron choline citrate in hypochromic anemia of pregnancy.
    Connecticut medicine, 1960, Volume: 24

    Topics: Anemia; Anemia, Hypochromic; Anemia, Sideroblastic; Choline; Female; Genetic Diseases, X-Linked; Hem

1960
Periplacental hemorrhage and renal necrosis in protein and choline deficient pregnant rats following progesterone administration. A preliminary report.
    American journal of obstetrics and gynecology, 1960, Volume: 80

    Topics: Animals; Choline; Choline Deficiency; Female; Hemorrhage; Humans; Kidney Diseases; Pregnancy; Pregna

1960
Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3

    Topics: Animals; Choline; Choline Deficiency; Cues; Cyclic AMP Response Element-Binding Protein; Female; Glu

2004
Folate deficiency during pregnancy impacts on methyl metabolism without affecting global DNA methylation in the rat fetus.
    The British journal of nutrition, 2007, Volume: 97, Issue:6

    Topics: Amino Acids; Animals; Choline; Diet; DNA Methylation; Female; Fetus; Folic Acid; Folic Acid Deficien

2007
Can tetracycline-induced fatty liver in pregnancy be attributed to choline deficiency?
    Medical hypotheses, 1982, Volume: 9, Issue:2

    Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Female; Humans; Lipotropic Agents; Liver; Pregnan

1982
Lithium treatment during pregnancy: a case study of erythrocyte choline content and lithium transport.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:10

    Topics: Adult; Bipolar Disorder; Choline; Erythrocytes; Female; Fetal Blood; Humans; Lithium; Lithium Carbon

1983
Perinatal complications and abnormal proton metabolite concentrations in frontal cortex of adolescents seen on magnetic resonance spectroscopy.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 2000, Volume: 13, Issue:1

    Topics: Aspartic Acid; Brain Damage, Chronic; Choline; Creatine; Female; Follow-Up Studies; Frontal Lobe; Hu

2000
Diffuse metabolic abnormalities in reversible posterior leukoencephalopathy syndrome.
    AJNR. American journal of neuroradiology, 2002, Volume: 23, Issue:5

    Topics: Adult; Aspartic Acid; Brain Diseases; Choline; Confusion; Creatine; Female; Headache; Humans; Magnet

2002
Hypertension in young rats following choline deficiency in maternal diets.
    The Journal of nutrition, 1971, Volume: 101, Issue:12

    Topics: Age Factors; Aging; Animals; Blood Pressure Determination; Choline; Choline Deficiency; Female; Feta

1971