choline and Coma
choline has been researched along with Coma in 18 studies
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma." | 7.74 | Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007) |
| "Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma." | 3.74 | Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007) |
| " We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
| "The status of comatose patient is currently established on the basis of the patient-exhibited behaviors." | 1.35 | Magnetic resonance spectroscopy and diffusion tensor imaging in coma survivors: promises and pitfalls. ( Boly, M; Galanaud, D; Laureys, S; Puybasset, L; Tshibanda, L; Vanhaudenhuyse, A, 2009) |
| "Choline treatment did not change brain choline content, and was not associated with clinical or radiological improvement." | 1.30 | One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. ( Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH, 1998) |
| "CDP-choline was used as the brain activator, and the effect of the intrathecally infused drug was investigated clinically." | 1.26 | Intrathecal pharmacotherapy in coma. ( Ogashiwa, M; Takeuchi, K, 1976) |
Research
Studies (18)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (55.56) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Lei, X | 1 |
| Qin, D | 1 |
| Zhu, G | 1 |
| Tshibanda, L | 1 |
| Vanhaudenhuyse, A | 1 |
| Galanaud, D | 1 |
| Boly, M | 1 |
| Laureys, S | 1 |
| Puybasset, L | 1 |
| Wartenberg, KE | 1 |
| Patsalides, A | 1 |
| Yepes, MS | 1 |
| Ashwal, S | 2 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Kido, D | 1 |
| Wong, YC | 1 |
| Au, WL | 1 |
| Xu, M | 1 |
| Ye, J | 1 |
| Lim, CC | 1 |
| Cohadon, F | 1 |
| Richer, E | 1 |
| Poletto, B | 1 |
| Holshouser, BA | 1 |
| Hinshaw, DB | 1 |
| Schell, RM | 1 |
| Bailey, L | 1 |
| Van Hove, JL | 1 |
| Lazeyras, F | 1 |
| Zeisel, SH | 1 |
| Bottiglieri, T | 1 |
| Hyland, K | 1 |
| Charles, HC | 1 |
| Gray, L | 1 |
| Jaeken, J | 1 |
| Kahler, SG | 1 |
| Espay, AJ | 1 |
| Bodensteiner, JB | 1 |
| Patel, H | 1 |
| Martí Viaño, JL | 1 |
| Sellés, J | 1 |
| Orts, A | 1 |
| Marco, J | 1 |
| Vega, F | 1 |
| Esplugues, J | 1 |
| Ogashiwa, M | 1 |
| Takeuchi, K | 1 |
| Saito, Y | 1 |
| Kitane, Y | 1 |
| Kawaguchi, N | 1 |
| Nojima, T | 1 |
| Centrone, G | 1 |
| Ragno, G | 1 |
| Calicchio, G | 1 |
| Kase, M | 1 |
| Ono, J | 1 |
| Yoshimasu, N | 1 |
| Hiyamuta, E | 1 |
| Sugiura, K | 1 |
| Montanini, S | 1 |
| De Salvo, R | 1 |
| Sinardi, AU | 1 |
| Fukuda, T | 1 |
| Araki, Y | 1 |
| Ratinoff, EC | 1 |
| Allerhand, J | 1 |
| Weingrow, S | 1 |
| Eisler, L | 1 |
| Latuf, NL | 1 |
| Colbachini, MJ | 1 |
| Galvào, JA | 1 |
Trials
2 trials available for choline and Coma
| Article | Year |
|---|---|
[A precursor of phospholipids in the treatment of severe traumatic comas].
Topics: Adult; Aged; Brain Injuries; Choline; Clinical Trials as Topic; Coma; Cytidine Diphosphate Choline; | 1982 |
[Use of cytidine-diphospho-choline (Nicholin) in coma].
Topics: Adolescent; Adult; Aged; Choline; Clinical Trials as Topic; Coma; Craniocerebral Trauma; Cytosine Nu | 1974 |
Other Studies
16 other studies available for choline and Coma
| Article | Year |
|---|---|
To Investigate the Effect of Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI) in the Diagnosis of Mild Craniocerebral Injury.
Topics: Brain Injuries; Brain Injuries, Traumatic; Choline; Coma; Creatinine; Diffusion Tensor Imaging; Huma | 2022 |
Magnetic resonance spectroscopy and diffusion tensor imaging in coma survivors: promises and pitfalls.
Topics: Anisotropy; Aspartic Acid; Brain Mapping; Choline; Coma; Creatine; Databases, Factual; Diffusion Mag | 2009 |
Is magnetic resonance spectroscopy superior to conventional diagnostic tools in hypoxic-ischemic encephalopathy?
Topics: Aspartic Acid; Brain; Brain Death; Cell Death; Choline; Coma; Creatine; Diffusion Magnetic Resonance | 2004 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.
Topics: Adult; Ammonia; Biomarkers; Brain; Brain Mapping; Cerebral Cortex; Choline; Citrulline; Citrullinemi | 2007 |
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool | 1996 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine; | 1998 |
Episodic coma in a new leukodystrophy.
Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post | 2002 |
[Antagonism of barbituric coma by stimulating products. Experimental study].
Topics: Animals; Body Weight; Choline; Coma; Cytidine Diphosphate Choline; Female; Glycolates; Injections, I | 1978 |
Intrathecal pharmacotherapy in coma.
Topics: Adult; Aged; Brain Injuries; Choline; Coma; Cytidine Diphosphate Choline; Electroencephalography; Fe | 1976 |
[Diurnal variation of serum cortisol and CDP-choline treatment of patients in the vegetative state].
Topics: Adolescent; Adult; Choline; Circadian Rhythm; Coma; Cytidine Diphosphate Choline; Female; Humans; Hy | 1975 |
[Use of citicoline in high dosages in acute cerebrovascular disease].
Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Choline; Coma; Consciousness; Cytidine Dip | 1986 |
Effect of CDP-choline in experimental cerebral hemorrhage.
Topics: Animals; Brain; Cerebral Hemorrhage; Cerebral Ventricles; Choline; Coma; Cytosine Nucleotides; Elect | 1974 |
[Effects of drugs on the postictal coma prolonged by repeated electroshocks in mice (author's transl)].
Topics: Animals; Choline; Coma; Cytosine Nucleotides; Electroshock; Glycolates; Male; Meclofenoxate; Mice; T | 1974 |
Plasma acetylcholine in coma secondary to cerebrovascular disease.
Topics: Acetylcholine; Adult; Aged; Cerebral Hemorrhage; Cerebrovascular Disorders; Choline; Chromatography, | 1968 |
[Clinical observations on the use of CDP-choline in consciousness disorders following head injuries].
Topics: Brain; Choline; Coma; Craniocerebral Trauma; Cytosine Nucleotides; Evaluation Studies as Topic; Huma | 1972 |