Page last updated: 2024-10-17

choline and Coma

choline has been researched along with Coma in 18 studies

Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Research Excerpts

ExcerptRelevanceReference
"Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma."7.74Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007)
"Adult-onset type II citrullinemia is an inborn error of urea cycle metabolism that can lead to hyperammonemic encephalopathy and coma."3.74Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients. ( Au, WL; Lim, CC; Wong, YC; Xu, M; Ye, J, 2007)
" We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol."3.72Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004)
"The status of comatose patient is currently established on the basis of the patient-exhibited behaviors."1.35Magnetic resonance spectroscopy and diffusion tensor imaging in coma survivors: promises and pitfalls. ( Boly, M; Galanaud, D; Laureys, S; Puybasset, L; Tshibanda, L; Vanhaudenhuyse, A, 2009)
"Choline treatment did not change brain choline content, and was not associated with clinical or radiological improvement."1.30One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. ( Bottiglieri, T; Charles, HC; Gray, L; Hyland, K; Jaeken, J; Kahler, SG; Lazeyras, F; Van Hove, JL; Zeisel, SH, 1998)
"CDP-choline was used as the brain activator, and the effect of the intrathecally infused drug was investigated clinically."1.26Intrathecal pharmacotherapy in coma. ( Ogashiwa, M; Takeuchi, K, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's2 (11.11)18.2507
2000's5 (27.78)29.6817
2010's0 (0.00)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Lei, X1
Qin, D1
Zhu, G1
Tshibanda, L1
Vanhaudenhuyse, A1
Galanaud, D1
Boly, M1
Laureys, S1
Puybasset, L1
Wartenberg, KE1
Patsalides, A1
Yepes, MS1
Ashwal, S2
Holshouser, B1
Tong, K1
Serna, T1
Osterdock, R1
Gross, M1
Kido, D1
Wong, YC1
Au, WL1
Xu, M1
Ye, J1
Lim, CC1
Cohadon, F1
Richer, E1
Poletto, B1
Holshouser, BA1
Hinshaw, DB1
Schell, RM1
Bailey, L1
Van Hove, JL1
Lazeyras, F1
Zeisel, SH1
Bottiglieri, T1
Hyland, K1
Charles, HC1
Gray, L1
Jaeken, J1
Kahler, SG1
Espay, AJ1
Bodensteiner, JB1
Patel, H1
Martí Viaño, JL1
Sellés, J1
Orts, A1
Marco, J1
Vega, F1
Esplugues, J1
Ogashiwa, M1
Takeuchi, K1
Saito, Y1
Kitane, Y1
Kawaguchi, N1
Nojima, T1
Centrone, G1
Ragno, G1
Calicchio, G1
Kase, M1
Ono, J1
Yoshimasu, N1
Hiyamuta, E1
Sugiura, K1
Montanini, S1
De Salvo, R1
Sinardi, AU1
Fukuda, T1
Araki, Y1
Ratinoff, EC1
Allerhand, J1
Weingrow, S1
Eisler, L1
Latuf, NL1
Colbachini, MJ1
Galvào, JA1

Trials

2 trials available for choline and Coma

ArticleYear
[A precursor of phospholipids in the treatment of severe traumatic comas].
    Neuro-Chirurgie, 1982, Volume: 28, Issue:4

    Topics: Adult; Aged; Brain Injuries; Choline; Clinical Trials as Topic; Coma; Cytidine Diphosphate Choline;

1982
[Use of cytidine-diphospho-choline (Nicholin) in coma].
    Minerva anestesiologica, 1974, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Choline; Clinical Trials as Topic; Coma; Craniocerebral Trauma; Cytosine Nu

1974

Other Studies

16 other studies available for choline and Coma

ArticleYear
To Investigate the Effect of Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI) in the Diagnosis of Mild Craniocerebral Injury.
    BioMed research international, 2022, Volume: 2022

    Topics: Brain Injuries; Brain Injuries, Traumatic; Choline; Coma; Creatinine; Diffusion Tensor Imaging; Huma

2022
Magnetic resonance spectroscopy and diffusion tensor imaging in coma survivors: promises and pitfalls.
    Progress in brain research, 2009, Volume: 177

    Topics: Anisotropy; Aspartic Acid; Brain Mapping; Choline; Coma; Creatine; Databases, Factual; Diffusion Mag

2009
Is magnetic resonance spectroscopy superior to conventional diagnostic tools in hypoxic-ischemic encephalopathy?
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2004, Volume: 14, Issue:2

    Topics: Aspartic Acid; Brain; Brain Death; Cell Death; Choline; Coma; Creatine; Diffusion Magnetic Resonance

2004
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
    Journal of neurotrauma, 2004, Volume: 21, Issue:11

    Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com

2004
Magnetic resonance spectroscopy in adult-onset citrullinemia: elevated glutamine levels in comatose patients.
    Archives of neurology, 2007, Volume: 64, Issue:7

    Topics: Adult; Ammonia; Biomarkers; Brain; Brain Mapping; Cerebral Cortex; Choline; Citrulline; Citrullinemi

2007
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury.
    The Journal of thoracic and cardiovascular surgery, 1996, Volume: 112, Issue:2

    Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool

1996
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
    Journal of inherited metabolic disease, 1998, Volume: 21, Issue:8

    Topics: Amino Acid Metabolism, Inborn Errors; Benzoic Acid; Brain Diseases; Choline; Coma; Female; Glycine;

1998
Episodic coma in a new leukodystrophy.
    Pediatric neurology, 2002, Volume: 26, Issue:2

    Topics: Aspartic Acid; Ataxia; Brain; Child; Choline; Coma; Creatine; Demyelinating Diseases; Epilepsy, Post

2002
[Antagonism of barbituric coma by stimulating products. Experimental study].
    Revista espanola de anestesiologia y reanimacion, 1978, Volume: 25, Issue:1

    Topics: Animals; Body Weight; Choline; Coma; Cytidine Diphosphate Choline; Female; Glycolates; Injections, I

1978
Intrathecal pharmacotherapy in coma.
    Acta neurochirurgica, 1976, Volume: 34, Issue:1-4

    Topics: Adult; Aged; Brain Injuries; Choline; Coma; Cytidine Diphosphate Choline; Electroencephalography; Fe

1976
[Diurnal variation of serum cortisol and CDP-choline treatment of patients in the vegetative state].
    Horumon to rinsho. Clinical endocrinology, 1975, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Choline; Circadian Rhythm; Coma; Cytidine Diphosphate Choline; Female; Humans; Hy

1975
[Use of citicoline in high dosages in acute cerebrovascular disease].
    Minerva medica, 1986, Mar-17, Volume: 77, Issue:11

    Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Choline; Coma; Consciousness; Cytidine Dip

1986
Effect of CDP-choline in experimental cerebral hemorrhage.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:5

    Topics: Animals; Brain; Cerebral Hemorrhage; Cerebral Ventricles; Choline; Coma; Cytosine Nucleotides; Elect

1974
[Effects of drugs on the postictal coma prolonged by repeated electroshocks in mice (author's transl)].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1974, Jun-25, Volume: 65, Issue:6

    Topics: Animals; Choline; Coma; Cytosine Nucleotides; Electroshock; Glycolates; Male; Meclofenoxate; Mice; T

1974
Plasma acetylcholine in coma secondary to cerebrovascular disease.
    Neurology, 1968, Volume: 18, Issue:4

    Topics: Acetylcholine; Adult; Aged; Cerebral Hemorrhage; Cerebrovascular Disorders; Choline; Chromatography,

1968
[Clinical observations on the use of CDP-choline in consciousness disorders following head injuries].
    Arquivos de neuro-psiquiatria, 1972, Volume: 30, Issue:3

    Topics: Brain; Choline; Coma; Craniocerebral Trauma; Cytosine Nucleotides; Evaluation Studies as Topic; Huma

1972