choline has been researched along with Cognitive Decline in 42 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with higher choline and betaine levels had lower risk of cognitive impairment after ischemic stroke, supporting promising prognostic roles of choline pathway nutrients for poststroke cognitive impairment." | 9.41 | Choline Pathway Nutrients and Metabolites and Cognitive Impairment After Acute Ischemic Stroke. ( Bu, X; Che, B; Ju, Z; Lu, Z; Qian, S; Wang, A; Xu, T; Zhang, J; Zhang, Y; Zheng, X; Zhong, C, 2021) |
| "To assess the effect of choline in ameliorating lipopolysaccharide (LPS)-induced central nervous system inflammation and cognitive deficits in mice and explore the underlying mechanism." | 7.85 | [Choline improves lipopolysaccharide-induced central nervous system inflammatory response and cognitive dysfunction in mice]. ( DU, CY; Feng, ZG; Jin, SY; Wang, H; Yu, J; Zhang, N; Zhang, WD; Zhao, WX, 2017) |
| "Patients with higher choline and betaine levels had lower risk of cognitive impairment after ischemic stroke, supporting promising prognostic roles of choline pathway nutrients for poststroke cognitive impairment." | 5.41 | Choline Pathway Nutrients and Metabolites and Cognitive Impairment After Acute Ischemic Stroke. ( Bu, X; Che, B; Ju, Z; Lu, Z; Qian, S; Wang, A; Xu, T; Zhang, J; Zhang, Y; Zheng, X; Zhong, C, 2021) |
| "We examined prospective associations of TMAO, γ-butyrobetaine, crotonobetaine, carnitine, choline, and betaine with risk of cognitive impairment and dementia among older adults aged 65 years and older in the Cardiovascular Health Study (CHS)." | 4.12 | Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study. ( de Oliveira Otto, MC; Fretts, A; Hazen, SL; Lai, HTM; Lee, Y; Lemaitre, RN; Li, XS; Lopez, O; Mozaffarian, D; Nemet, I; Newman, AB; Siscovick, DS; Tang, WHW; Wang, M; Wang, Z, 2022) |
| "To assess the effect of choline in ameliorating lipopolysaccharide (LPS)-induced central nervous system inflammation and cognitive deficits in mice and explore the underlying mechanism." | 3.85 | [Choline improves lipopolysaccharide-induced central nervous system inflammatory response and cognitive dysfunction in mice]. ( DU, CY; Feng, ZG; Jin, SY; Wang, H; Yu, J; Zhang, N; Zhang, WD; Zhao, WX, 2017) |
| "Synaptic loss is a major hallmark of Alzheimer's disease (AD)." | 2.79 | The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. ( de Waal, H; Kamphuis, PJ; Lansbergen, MM; Maestú, F; Scheltens, P; Stam, CJ; van Straaten, EC; Wieggers, RL, 2014) |
| "Choline interventions were administered at different times relative to alcohol exposure, impacting on their success to prevent deficits for specific outcomes." | 2.58 | Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies. ( Akison, LK; Boyd, RN; Kuo, J; Moritz, KM; Reid, N, 2018) |
| "The study included 120 patients with type 1 diabetes aged 18 to 45 years suffering from cognitive impairment, and 30 people without cognitive decline and the control group (n=30) healthy people without diabetes." | 1.72 | Interhemispheric asymmetry of the brain in patients with type 1 diabetes mellitus and cognitive impairment. ( Aremu, SO; Gerget, OM; Kanev, AF; Kilina, OY; Kudlay, DA; Matveeva, MV; Oleynik, OA; Samoilova, YG; Tonkih, OS, 2022) |
| "Chronic cerebral ischemia leads to vascular cognitive impairment (VCI) that exacerbates along with ischemia time and eventually develops into dementia." | 1.62 | Longitudinal tracing of neurochemical metabolic disorders in working memory neural circuit and optogenetics modulation in rats with vascular cognitive impairment. ( Chen, L; Dai, Y; He, X; Huang, J; Jia, W; Jin, T; Li, J; Liang, S; Lin, H; Liu, W; Tao, J; Wu, J; Yang, M, 2021) |
| "Choline treatments could restore the membrane lipids, repair cellular organelles and protect mutant cells from acute iron overload." | 1.56 | Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. ( Agarwal, P; Bakovic, M; Brady, L; Distelmaier, F; Dolinsky, VW; Fagerberg, CR; Gade, E; Hejbøl, EK; Jamra, RA; Kibæk, M; Klee, D; Larsen, MJ; Markovic, L; Nagy, P; Rouse, N; Schrøder, HD; Seibt, A; Tarnopolsky, M; Taylor, A; Wieczorek, D, 2020) |
| "Choline is a B-like vitamin nutrient found in common foods that is important in various cell functions." | 1.51 | Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation. ( Ferreira, E; Fux, C; Knowles, S; Oddo, S; Rodin, A; Velazquez, R; Winslow, W, 2019) |
| "Amnestic mild cognitive impairment (aMCI) is often the prodromal stage to AD." | 1.43 | (1)H-MRS asymmetry changes in the anterior and posterior cingulate gyrus in patients with mild cognitive impairment and mild Alzheimer's disease. ( Chen, W; Chen, X; Guo, Z; Hou, H; Liu, X; Shen, Y; Wei, F, 2016) |
| "Choline is a water-soluble essential nutrient, used as a dietary supplement in different diseases." | 1.40 | Choline associated hypersexuality in a 79-year-old man. ( Bramanti, P; Calabrò, RS; Cordici, F; Genovese, C, 2014) |
| "Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance." | 1.39 | Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. ( Bjelland, I; Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, DA; Tell, GS; Ueland, PM; Vollset, SE, 2013) |
| "The mild cognitive impairment in Parkinson's disease (PD-MCI) has received increasing attention, of which the diagnosis is challenging." | 1.39 | Marked N-acetylaspartate and choline metabolite changes in Parkinson's disease patients with mild cognitive impairment. ( Gan, R; Huang, B; Huang, Z; Nie, K; Wang, L; Zhang, Y; Zhao, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 25 (59.52) | 24.3611 |
| 2020's | 17 (40.48) | 2.80 |
| Authors | Studies |
|---|---|
| Bortz, J | 1 |
| Klatt, KC | 1 |
| Wallace, TC | 1 |
| de Oliveira Otto, MC | 1 |
| Li, XS | 1 |
| Wang, Z | 1 |
| Siscovick, DS | 1 |
| Newman, AB | 1 |
| Lai, HTM | 1 |
| Nemet, I | 1 |
| Lee, Y | 1 |
| Wang, M | 1 |
| Fretts, A | 1 |
| Lemaitre, RN | 1 |
| Tang, WHW | 1 |
| Lopez, O | 1 |
| Hazen, SL | 1 |
| Mozaffarian, D | 1 |
| Samoilova, YG | 1 |
| Matveeva, MV | 1 |
| Tonkih, OS | 1 |
| Kudlay, DA | 1 |
| Oleynik, OA | 1 |
| Aremu, SO | 1 |
| Kilina, OY | 1 |
| Kanev, AF | 1 |
| Gerget, OM | 1 |
| Huang, X | 1 |
| Lai, S | 1 |
| Lu, X | 1 |
| Wang, Y | 1 |
| Zhang, Y | 6 |
| Chen, G | 1 |
| Chen, P | 1 |
| Ye, K | 1 |
| Duan, M | 1 |
| Song, K | 1 |
| Zhong, S | 1 |
| Jia, Y | 1 |
| Wang, G | 3 |
| Li, R | 3 |
| Liu, R | 3 |
| Yu, Z | 3 |
| Zhang, Z | 3 |
| Wan, Z | 3 |
| Levin, O | 1 |
| Vints, WAJ | 1 |
| Ziv, G | 1 |
| Katkutė, G | 1 |
| Kušleikienė, S | 1 |
| Valatkevičienė, K | 1 |
| Sheoran, S | 1 |
| Drozdova-Statkevičienė, M | 1 |
| Gleiznienė, R | 1 |
| Pääsuke, M | 1 |
| Dudonienė, V | 1 |
| Himmelreich, U | 1 |
| Česnaitienė, VJ | 1 |
| Masiulis, N | 1 |
| Tu, R | 1 |
| Xia, J | 1 |
| Velazquez, R | 1 |
| Ferreira, E | 1 |
| Knowles, S | 1 |
| Fux, C | 1 |
| Rodin, A | 1 |
| Winslow, W | 1 |
| Oddo, S | 1 |
| Rafi, H | 1 |
| Ahmad, F | 1 |
| Anis, J | 1 |
| Khan, R | 1 |
| Rafiq, H | 1 |
| Farhan, M | 1 |
| Hildre, AS | 1 |
| Solvang, SH | 1 |
| Aarsland, D | 1 |
| Midtun, Ø | 1 |
| McCann, A | 1 |
| Ervik, AO | 1 |
| Nygård, O | 1 |
| Ueland, PM | 2 |
| Nordrehaug, JE | 1 |
| Giil, LM | 1 |
| Singh, V | 1 |
| Mishra, VN | 1 |
| Prajapati, GD | 1 |
| Ampapathi, RS | 1 |
| Thakur, MK | 1 |
| Fagerberg, CR | 1 |
| Taylor, A | 1 |
| Distelmaier, F | 1 |
| Schrøder, HD | 1 |
| Kibæk, M | 1 |
| Wieczorek, D | 1 |
| Tarnopolsky, M | 1 |
| Brady, L | 1 |
| Larsen, MJ | 1 |
| Jamra, RA | 1 |
| Seibt, A | 1 |
| Hejbøl, EK | 1 |
| Gade, E | 1 |
| Markovic, L | 1 |
| Klee, D | 1 |
| Nagy, P | 1 |
| Rouse, N | 1 |
| Agarwal, P | 1 |
| Dolinsky, VW | 1 |
| Bakovic, M | 1 |
| Wang, QJ | 1 |
| Shen, YE | 1 |
| Wang, X | 1 |
| Fu, S | 1 |
| Zhang, X | 1 |
| Zhang, YN | 1 |
| Wang, RT | 1 |
| Lepping, RJ | 1 |
| Montgomery, RN | 1 |
| Sharma, P | 1 |
| Mahnken, JD | 1 |
| Vidoni, ED | 1 |
| Choi, IY | 1 |
| Sarnak, MJ | 1 |
| Brooks, WM | 1 |
| Burns, JM | 1 |
| Gupta, A | 1 |
| Zhong, C | 1 |
| Lu, Z | 1 |
| Che, B | 1 |
| Qian, S | 1 |
| Zheng, X | 1 |
| Wang, A | 1 |
| Bu, X | 1 |
| Zhang, J | 1 |
| Ju, Z | 1 |
| Xu, T | 1 |
| Lin, H | 1 |
| Jin, T | 1 |
| Chen, L | 2 |
| Dai, Y | 1 |
| Jia, W | 1 |
| He, X | 1 |
| Yang, M | 1 |
| Li, J | 1 |
| Liang, S | 1 |
| Wu, J | 1 |
| Huang, J | 1 |
| Liu, W | 1 |
| Tao, J | 1 |
| Jasiecki, J | 1 |
| Targońska, M | 1 |
| Wasąg, B | 1 |
| Johns, BE | 1 |
| Ficken, M | 1 |
| Engberg, ME | 1 |
| Wecker, L | 1 |
| Philpot, RM | 1 |
| Yu, J | 1 |
| Zhao, WX | 1 |
| DU, CY | 1 |
| Zhang, N | 1 |
| Zhang, WD | 1 |
| Jin, SY | 1 |
| Wang, H | 1 |
| Feng, ZG | 1 |
| Shih, CM | 1 |
| Lai, JJ | 1 |
| Chang, CC | 1 |
| Chen, CS | 1 |
| Yeh, YC | 1 |
| Jaw, TS | 1 |
| Hsu, JS | 1 |
| Li, CW | 1 |
| McDougall, M | 1 |
| Choi, J | 1 |
| Magnusson, K | 1 |
| Truong, L | 1 |
| Tanguay, R | 1 |
| Traber, MG | 1 |
| Akison, LK | 1 |
| Kuo, J | 1 |
| Reid, N | 1 |
| Boyd, RN | 1 |
| Moritz, KM | 1 |
| Alakkas, A | 1 |
| Ellis, RJ | 1 |
| Watson, CW | 1 |
| Umlauf, A | 1 |
| Heaton, RK | 1 |
| Letendre, S | 1 |
| Collier, A | 1 |
| Marra, C | 1 |
| Clifford, DB | 1 |
| Gelman, B | 1 |
| Sacktor, N | 1 |
| Morgello, S | 1 |
| Simpson, D | 1 |
| McCutchan, JA | 1 |
| Kallianpur, A | 1 |
| Gianella, S | 1 |
| Marcotte, T | 1 |
| Grant, I | 1 |
| Fennema-Notestine, C | 1 |
| Reddan, JM | 1 |
| Macpherson, H | 1 |
| White, DJ | 1 |
| Scholey, A | 1 |
| Pipingas, A | 1 |
| Ren, X | 1 |
| Keeney, JTR | 1 |
| Miriyala, S | 1 |
| Noel, T | 1 |
| Powell, DK | 1 |
| Chaiswing, L | 1 |
| Bondada, S | 1 |
| St Clair, DK | 1 |
| Butterfield, DA | 1 |
| Liu, Y | 1 |
| Cai, ZL | 1 |
| Xue, S | 1 |
| Zhou, X | 1 |
| Wu, F | 1 |
| Kantarci, K | 1 |
| Menezes, TL | 1 |
| Andrade-Valença, LP | 1 |
| Valença, MM | 1 |
| Calabrò, RS | 1 |
| Cordici, F | 1 |
| Genovese, C | 1 |
| Bramanti, P | 1 |
| Tumati, S | 1 |
| Martens, S | 1 |
| Aleman, A | 1 |
| Targosz-Gajniak, MG | 1 |
| Siuda, JS | 1 |
| Wicher, MM | 1 |
| Banasik, TJ | 1 |
| Bujak, MA | 1 |
| Augusciak-Duma, AM | 1 |
| Opala, G | 1 |
| de Waal, H | 1 |
| Stam, CJ | 1 |
| Lansbergen, MM | 1 |
| Wieggers, RL | 1 |
| Kamphuis, PJ | 1 |
| Scheltens, P | 1 |
| Maestú, F | 1 |
| van Straaten, EC | 1 |
| Suriyajakryuththana, W | 1 |
| Tuntiyatorn, L | 1 |
| Teepprasarn, N | 1 |
| Sukying, C | 1 |
| Almuqbel, M | 1 |
| Melzer, TR | 1 |
| Myall, DJ | 1 |
| MacAskill, MR | 1 |
| Pitcher, TL | 1 |
| Livingston, L | 1 |
| Wood, KL | 1 |
| Keenan, RJ | 1 |
| Dalrymple-Alford, JC | 1 |
| Anderson, TJ | 1 |
| Cheong, JL | 1 |
| Bainbridge, A | 1 |
| Anderson, PJ | 1 |
| Lee, KJ | 1 |
| Burnett, AC | 1 |
| Thompson, DK | 1 |
| Roberts, G | 1 |
| Wood, SJ | 1 |
| Doyle, LW | 1 |
| Robertson, NJ | 1 |
| Guo, Z | 1 |
| Liu, X | 1 |
| Hou, H | 1 |
| Wei, F | 1 |
| Chen, X | 1 |
| Shen, Y | 1 |
| Chen, W | 1 |
| Foy, CM | 1 |
| Daly, EM | 1 |
| Glover, A | 1 |
| O'Gorman, R | 1 |
| Simmons, A | 1 |
| Murphy, DG | 1 |
| Lovestone, S | 1 |
| Wang, T | 1 |
| Xiao, S | 1 |
| Li, X | 1 |
| Ding, B | 1 |
| Ling, H | 1 |
| Chen, K | 1 |
| Fang, Y | 1 |
| Fayed, N | 1 |
| Modrego, PJ | 1 |
| Rojas-Salinas, G | 1 |
| Aguilar, K | 1 |
| Walecki, J | 1 |
| Barcikowska, M | 1 |
| Ćwikła, JB | 1 |
| Gabryelewicz, T | 1 |
| Nurk, E | 1 |
| Refsum, H | 1 |
| Bjelland, I | 1 |
| Drevon, CA | 1 |
| Tell, GS | 1 |
| Vollset, SE | 1 |
| Engedal, K | 1 |
| Nygaard, HA | 1 |
| Smith, DA | 1 |
| Nie, K | 1 |
| Huang, B | 1 |
| Wang, L | 2 |
| Zhao, J | 1 |
| Huang, Z | 1 |
| Gan, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cognitive Impairment and Imaging Correlates in End Stage Renal Disease[NCT01883349] | 140 participants (Anticipated) | Observational | 2013-03-31 | Recruiting | |||
| Open Label Study for the Use of Tyrosine Kinase Inhibitors for Treatment of Cognitive Decline Due to Degenerative Dementias[NCT02921477] | Phase 1 | 150 participants (Anticipated) | Interventional | 2016-09-30 | Enrolling by invitation | ||
| Focused Ultrasound Delivery of Exosomes for Treatment of Refractory Depression, Anxiety, and Neurodegenerative Dementias[NCT04202770] | 300 participants (Anticipated) | Interventional | 2019-12-01 | Suspended (stopped due to Pending COVID-19 pandemic; pending status of product development) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for choline and Cognitive Decline
| Article | Year |
|---|---|
Stroke and Vascular Cognitive Impairment: The Role of Intestinal Microbiota Metabolite TMAO.
Topics: Choline; Cognitive Dysfunction; Gastrointestinal Microbiome; Humans; Inflammation; Stroke; Thrombosi | 2024 |
The Role of Butyrylcholinesterase and Iron in the Regulation of Cholinergic Network and Cognitive Dysfunction in Alzheimer's Disease Pathogenesis.
Topics: Alzheimer Disease; Animals; Brain; Butyrylcholinesterase; Choline; Cognitive Dysfunction; Humans; Ir | 2021 |
Effect of Choline Supplementation on Neurological, Cognitive, and Behavioral Outcomes in Offspring Arising from Alcohol Exposure During Development: A Quantitative Systematic Review of Clinical and Preclinical Studies.
Topics: Alcohol Drinking; Animals; Animals, Newborn; Choline; Clinical Trials as Topic; Cognition; Cognitive | 2018 |
Examining the relationship between nutrition and cerebral structural integrity in older adults without dementia.
Topics: Aged; Aged, 80 and over; Aging; Brain; Choline; Cognition; Cognitive Dysfunction; Dementia; Diet; Di | 2019 |
Proton MRS in mild cognitive impairment.
Topics: Alzheimer Disease; Animals; Aspartic Acid; Biomarkers; Brain; Choline; Cognitive Dysfunction; Creati | 2013 |
Magnetic resonance spectroscopy in mild cognitive impairment: systematic review and meta-analysis.
Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Humans; Inositol; Magnetic Resonance Spectr | 2013 |
2 trials available for choline and Cognitive Decline
| Article | Year |
|---|---|
Choline Pathway Nutrients and Metabolites and Cognitive Impairment After Acute Ischemic Stroke.
Topics: Aged; Antihypertensive Agents; Brain Ischemia; China; Choline; Cognition; Cognition Disorders; Cogni | 2021 |
The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study.
Topics: Aged; Alzheimer Disease; Brain; Choline; Cognitive Dysfunction; Docosahexaenoic Acids; Eicosapentaen | 2014 |
34 other studies available for choline and Cognitive Decline
| Article | Year |
|---|---|
Perspective: Estrogen and the Risk of Cognitive Decline: A Missing Choline(rgic) Link?
Topics: Alzheimer Disease; Choline; Cholinergic Agents; Cognitive Dysfunction; Estrogens; Female; Humans; Me | 2022 |
Longitudinal Associations of Plasma TMAO and Related Metabolites with Cognitive Impairment and Dementia in Older Adults: The Cardiovascular Health Study.
Topics: Animals; Betaine; Carnitine; Choline; Cognitive Dysfunction; Dementia; Medicare; Methylamines; Unite | 2022 |
Interhemispheric asymmetry of the brain in patients with type 1 diabetes mellitus and cognitive impairment.
Topics: Brain; Choline; Cognitive Dysfunction; Diabetes Mellitus, Type 1; Humans; Magnetic Resonance Imaging | 2022 |
Cognitive dysfunction and neurometabolic alternations in major depressive disorder with gastrointestinal symptoms.
Topics: Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Depressive Disorder, Major; Humans; Proton | 2023 |
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived | 2023 |
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived | 2023 |
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived | 2023 |
Trimethylamine N-oxide aggravated cognitive impairment from APP/PS1 mice and protective roles of voluntary exercise.
Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Betaine; Brain-Derived | 2023 |
Neurometabolic correlates of posturography in normal aging and older adults with mild cognitive impairment: Evidence from a
Topics: Aged; Aging; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Glutamine; Humans; Inositol; P | 2023 |
Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation.
Topics: Alzheimer Disease; Animals; Brain; Choline; Cognitive Dysfunction; Dietary Supplements; Longevity; M | 2019 |
Comparative Effectiveness of Agmatine and Choline Treatment in Rats with Cognitive Impairment Induced by AlCl
Topics: Agmatine; Animals; Choline; Cognitive Dysfunction; Discrimination Learning; Male; Maze Learning; Mem | 2020 |
Components of the choline oxidation pathway modify the association between the apolipoprotein ε4 gene variant and cognitive decline in patients with dementia.
Topics: Aged; Alzheimer Disease; Apolipoprotein E4; Choline; Cognitive Dysfunction; Dementia; Female; Humans | 2020 |
Quantitative metabolic biomarker analysis of mild cognitive impairment in eastern U.P. and Bihar population.
Topics: Aged; Alanine; Biomarkers; Blood Glucose; Blood Specimen Collection; Choline; Cognitive Dysfunction; | 2020 |
Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration.
Topics: Adolescent; Antigens, CD; Ataxia; Atrophy; Cerebellum; Choline; Cognitive Dysfunction; Cytoplasmic V | 2020 |
Concomitant memantine and
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Biomarkers; Choline; Cognitive Dysfunctio | 2020 |
Normalization of Cerebral Blood Flow, Neurochemicals, and White Matter Integrity after Kidney Transplantation.
Topics: Adult; Aged; Case-Control Studies; Cerebrovascular Circulation; Choline; Cognition; Cognitive Dysfun | 2021 |
Longitudinal tracing of neurochemical metabolic disorders in working memory neural circuit and optogenetics modulation in rats with vascular cognitive impairment.
Topics: Animals; Brain; Brain Ischemia; Choline; Cognitive Dysfunction; Glutamic Acid; Magnetic Resonance Sp | 2021 |
Increasing dietary choline attenuates spatial memory deficits resulting from exposure to the chemotherapeutic agents cyclophosphamide and doxorubicin.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Choline; Cognitive Dysfunct | 2021 |
[Choline improves lipopolysaccharide-induced central nervous system inflammatory response and cognitive dysfunction in mice].
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium-Binding Proteins; Central Nervous System; | 2017 |
Comparison of LCModel and SAGE in Analysis of Brain Metabolite Concentrations-A study of Patients with Mild Cognitive Impairment.
Topics: Aspartic Acid; Brain; Case-Control Studies; Choline; Cognitive Dysfunction; Creatine; Humans; Magnet | 2017 |
Chronic vitamin E deficiency impairs cognitive function in adult zebrafish via dysregulation of brain lipids and energy metabolism.
Topics: Animals; Avoidance Learning; Brain; Choline; Chronic Disease; Cognition; Cognitive Dysfunction; Doco | 2017 |
White matter damage, neuroinflammation, and neuronal integrity in HAND.
Topics: Adult; AIDS Dementia Complex; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartic Acid; | 2019 |
The triangle of death of neurons: Oxidative damage, mitochondrial dysfunction, and loss of choline-containing biomolecules in brains of mice treated with doxorubicin. Advanced insights into mechanisms of chemotherapy induced cognitive impairment ("chemobr
Topics: Animals; Antibiotics, Antineoplastic; Brain; Choline; Cognitive Dysfunction; Doxorubicin; Male; Mice | 2019 |
Proxies of cognitive reserve and their effects on neuropsychological performance in patients with mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Biomarkers; Choline; Cognitive Dysfunction; Cognitive Reserv | 2013 |
Magnetic resonance imaging study cannot individually distinguish individuals with mild cognitive impairment, mild Alzheimer's disease, and normal aging.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Di | 2013 |
Choline associated hypersexuality in a 79-year-old man.
Topics: Aged; Choline; Cognitive Dysfunction; Humans; Libido; Male; Paraphilic Disorders; Sexual Behavior; T | 2014 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Magnetic resonance spectroscopy as a predictor of conversion of mild cognitive impairment to dementia.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Choline; Cognitive Dysfunction; Creatine; Dementia; D | 2013 |
Proton magnetic resonance spectroscopy in mild cognitive impairment and Alzheimer's disease: a preliminary study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive | 2014 |
Metabolite ratios in the posterior cingulate cortex do not track cognitive decline in Parkinson's disease in a clinical setting.
Topics: Aged; Aged, 80 and over; Aspartic Acid; Bayes Theorem; Case-Control Studies; Choline; Cognitive Dysf | 2016 |
Altered posterior cingulate brain metabolites and cognitive dysfunction in preterm adolescents.
Topics: Adolescent; Aspartic Acid; Australia; Brain; Cell Membrane; Choline; Cognition; Cognition Disorders; | 2016 |
(1)H-MRS asymmetry changes in the anterior and posterior cingulate gyrus in patients with mild cognitive impairment and mild Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; Dominance, Cerebra | 2016 |
Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Cognitive | 2011 |
Using proton magnetic resonance spectroscopy to identify mild cognitive impairment.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Case-Control Studies; Choline; Cognitive Dysfunction; | 2012 |
Brain glutamate levels are decreased in Alzheimer's disease: a magnetic resonance spectroscopy study.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Creatine; | 2011 |
N-acetylaspartate, choline, myoinositol, glutamine and glutamate (glx) concentration changes in proton MR spectroscopy (1H MRS) in patients with mild cognitive impairment (MCI).
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Cognitive Dysfunction; Disease Progression; Female; | 2011 |
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Cognitive Dysfunction; Cohort Studies | 2013 |
Marked N-acetylaspartate and choline metabolite changes in Parkinson's disease patients with mild cognitive impairment.
Topics: Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Choline; Cognitive Dysfunction; Early Diagn | 2013 |