choline has been researched along with Cerebellar Ataxia in 16 studies
Cerebellar Ataxia: Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebrospinal fluid (CSF) amino acid neurotransmitters, related compounds, and their precursors, choline levels, and acetylcholinesterase activity were measured in the CSF of patients with cerebellar ataxia during a randomized, double-blind, crossover, placebo-controlled clinical trial of physostigmine salicylate." | 9.06 | Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia. ( Ferraro, TN; Giacobini, E; Hare, TA; Manyam, BV, 1990) |
| "In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia." | 7.66 | Oral choline in cerebellar ataxia. ( Kristensen, O; Lund, HI; Sehested, P, 1980) |
| "The use of orally administered choline chloride in the treatment of cerebellar and spinocerebellar ataxia was investigated by a short-term double-blind crossover trial in 20 patients with ataxia." | 7.66 | Choline chloride in the treatment of cerebellar and spinocerebellar ataxia. ( Livingstone, IR; Mastaglia, FL; Pennington, RJ; Skilbeck, C, 1981) |
| "Cerebrospinal fluid (CSF) amino acid neurotransmitters, related compounds, and their precursors, choline levels, and acetylcholinesterase activity were measured in the CSF of patients with cerebellar ataxia during a randomized, double-blind, crossover, placebo-controlled clinical trial of physostigmine salicylate." | 5.06 | Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia. ( Ferraro, TN; Giacobini, E; Hare, TA; Manyam, BV, 1990) |
| "In a double-blind crossover pilot study with placebo, choline chloride, the physiologic precursor of acetylcholine, was tested in six patients with cerebellar ataxia." | 3.66 | Oral choline in cerebellar ataxia. ( Kristensen, O; Lund, HI; Sehested, P, 1980) |
| "The use of orally administered choline chloride in the treatment of cerebellar and spinocerebellar ataxia was investigated by a short-term double-blind crossover trial in 20 patients with ataxia." | 3.66 | Choline chloride in the treatment of cerebellar and spinocerebellar ataxia. ( Livingstone, IR; Mastaglia, FL; Pennington, RJ; Skilbeck, C, 1981) |
| "The confirmed pharmacological treatment of cerebellar ataxia is still lacking." | 2.42 | Pharmacological treatments of cerebellar ataxia. ( Ogawa, M, 2004) |
| "Huntington's chorea, ataxias, Tourette's syndrome, schizophrenia, affective illness, and senile dementia of the Alzheimer type, has been implicated with a general underactivity of central cholinergic mechanisms." | 2.36 | The use of cholinergic precursors in neuropsychiatric diseases. ( Davis, KL; Rosenberg, GS, 1982) |
| "Five patients with undefined ataxia had a substantial decrease of pontine or cerebellar NAA/Cr ratio when compared with that of the control subjects." | 1.31 | Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia. ( Cosottini, M; Ferlini, A; Lolli, F; Macucci, M; Mascalchi, M; Plasmati, R; Salvi, F; Tassinari, CA; Tessa, C; Tosetti, M; Villari, N, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerrini, L | 1 |
| Belli, G | 1 |
| Mazzoni, L | 1 |
| Foresti, S | 1 |
| Ginestroni, A | 1 |
| Della Nave, R | 1 |
| Diciotti, S | 1 |
| Mascalchi, M | 2 |
| Ogawa, M | 1 |
| Jurkiewicz, E | 1 |
| Mierzewska, H | 1 |
| Bekiesińska-Figatowska, M | 1 |
| Pakua-Kościesza, I | 1 |
| Kmieć, T | 1 |
| Scheper, G | 1 |
| van der Knaap, MS | 1 |
| Pronicka, E | 1 |
| Wilkinson, ID | 1 |
| Hadjivassiliou, M | 1 |
| Dickson, JM | 1 |
| Wallis, L | 1 |
| Grünewald, RA | 1 |
| Coley, SC | 1 |
| Widjaja, E | 1 |
| Griffiths, PD | 1 |
| Rosenberg, GS | 1 |
| Davis, KL | 1 |
| Austin, CA | 1 |
| Mundy, KI | 1 |
| Dorey, S | 1 |
| Lawrence, CM | 1 |
| Millac, P | 1 |
| Stout, GS | 1 |
| Ward, JW | 1 |
| Sehested, P | 1 |
| Lund, HI | 1 |
| Kristensen, O | 1 |
| Livingstone, IR | 2 |
| Mastaglia, FL | 2 |
| Pennington, RJ | 1 |
| Skilbeck, C | 1 |
| Trouillas, P | 1 |
| Cosottini, M | 1 |
| Lolli, F | 1 |
| Salvi, F | 1 |
| Tessa, C | 1 |
| Macucci, M | 1 |
| Tosetti, M | 1 |
| Plasmati, R | 1 |
| Ferlini, A | 1 |
| Tassinari, CA | 1 |
| Villari, N | 1 |
| Legg, N | 1 |
| Legg, NJ | 1 |
| Manyam, BV | 1 |
| Giacobini, E | 1 |
| Ferraro, TN | 1 |
| Hare, TA | 1 |
| Finocchiaro, G | 1 |
| Di Donato, S | 1 |
| Madonna, M | 1 |
| Fusi, R | 1 |
| Ladinsky, H | 1 |
| Consolo, S | 1 |
2 reviews available for choline and Cerebellar Ataxia
| Article | Year |
|---|---|
Pharmacological treatments of cerebellar ataxia.
Topics: Cerebellar Ataxia; Choline; Cholinesterase Inhibitors; Clinical Trials as Topic; Cycloserine; Ergolo | 2004 |
The use of cholinergic precursors in neuropsychiatric diseases.
Topics: Acetylcholine; Alzheimer Disease; Animals; Bipolar Disorder; Brain; Cerebellar Ataxia; Choline; Huma | 1982 |
3 trials available for choline and Cerebellar Ataxia
| Article | Year |
|---|---|
The use of choline chloride in ataxic disorders.
Topics: Adult; Aged; Cerebellar Ataxia; Child; Choline; Clinical Trials as Topic; Dose-Response Relationship | 1980 |
Choline chloride in the treatment of ataxia.
Topics: Cerebellar Ataxia; Choline; Clinical Trials as Topic; Double-Blind Method; Humans; Random Allocation | 1979 |
Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia.
Topics: Acetylcholine; Acetylcholinesterase; Adult; Amino Acids; Central Nervous System; Cerebellar Ataxia; | 1990 |
11 other studies available for choline and Cerebellar Ataxia
| Article | Year |
|---|---|
Impact of cerebrospinal fluid contamination on brain metabolites evaluation with 1H-MR spectroscopy: a single voxel study of the cerebellar vermis in patients with degenerative ataxias.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Cerebellar Ataxia; Cerebellum; Choline; Creatine; | 2009 |
MRI of a family with leukoencephalypathy with vanishing white matter.
Topics: Adolescent; Amino Acid Substitution; Aspartic Acid; Brain; Case-Control Studies; Cerebellar Ataxia; | 2005 |
Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia.
Topics: Adult; Aged; Aged, 80 and over; Aspartic Acid; Celiac Disease; Cerebellar Ataxia; Cerebellar Nuclei; | 2005 |
Low dose choline chloride in cerebellar degeneration.
Topics: Adolescent; Adult; Aged; Cerebellar Ataxia; Cerebellar Diseases; Choline; Dose-Response Relationship | 1984 |
Oral choline in cerebellar ataxia.
Topics: Administration, Oral; Cerebellar Ataxia; Choline; Double-Blind Method; Humans; Pilot Projects; Place | 1980 |
Choline chloride in the treatment of cerebellar and spinocerebellar ataxia.
Topics: Adult; Cerebellar Ataxia; Choline; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fr | 1981 |
[Theoretical basis and proposals for neuropharmacology of cerebellar ataxia].
Topics: Cerebellar Ataxia; Cerebellum; Choline; Humans; Neurotransmitter Agents; Norepinephrine; Physostigmi | 1993 |
Proton MR spectroscopy of the cerebellum and pons in patients with degenerative ataxia.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Aspartic Acid; Ataxia; Case-Control Studies; Cerebell | 2002 |
Oral choline in cerebellar ataxia.
Topics: Baclofen; Cerebellar Ataxia; Choline; Humans; Valproic Acid | 1979 |
Oral choline in cerebellar ataxia.
Topics: Administration, Oral; Cerebellar Ataxia; Choline; Humans; Male; Middle Aged; Motor Skills | 1978 |
An approach using lecithin treatment for olivopontocerebellar atrophies.
Topics: Adult; Cerebellar Ataxia; Cholesterol, HDL; Choline; Cranial Nerves; Electromyography; Female; Human | 1985 |