choline has been researched along with Brain Injuries in 80 studies
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "F98 gliomas were induced in 26 rats." | 5.33 | Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L: -tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat. ( Biollaz, G; Buck, A; Goepfert, K; Lutz, A; Pahnke, J; Spaeth, N; Treyer, V; Weber, B; Westera, G; Wyss, MT, 2006) |
| "Semiquantitative analysis of NAA relative to creatine-containing compounds (Cr) and choline (Cho) was carried out from proton spectra obtained by means of chemical shift (CS) imaging and single-voxel (SV) methods in 25 patients with severe traumatic brain injuries (TBIs) (Glasgow Coma Scale scores < or = 8) using a 1." | 5.13 | Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy. ( Aygok, GA; Bullock, RM; Fatouros, PP; Marmarou, A; Portella, G; Signoretti, S, 2008) |
| " We also did not find a correlation between the amount of Glx and the initial Glasgow Coma Scale score, duration of coma, nor with changes in spectral metabolites, including N-acetyl aspartate, choline, and myoinositol." | 3.72 | Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury. ( Ashwal, S; Gross, M; Holshouser, B; Kido, D; Osterdock, R; Serna, T; Tong, K, 2004) |
| "Eighty cases of nasopharyngeal cancer treated with radiotherapy within the same period underwent MRS imaging before or after radiotherapy." | 1.40 | Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction. ( Chen, WS; Hong, L; Li, CQ; Li, JJ; Wang, F; Xing, ZB; Zhang, JH, 2014) |
| "Choline diet promotes improvement of the brain cognitive functions in rats with moderate-to-severe traumatic brain injury." | 1.39 | Optimization of choline administration regimen for correction of cognitive functions in rats after brain injury. ( Gusev, VB; Guseva, MV; Kamenskii, AA, 2013) |
| "F98 gliomas were induced in 26 rats." | 1.33 | Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L: -tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat. ( Biollaz, G; Buck, A; Goepfert, K; Lutz, A; Pahnke, J; Spaeth, N; Treyer, V; Weber, B; Westera, G; Wyss, MT, 2006) |
| "Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function." | 1.33 | Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury. ( Barker, PB; Degaonkar, M; Earley, CJ; Halbower, AC; Mahone, EM; Marcus, CL; Prahme, MC; Smith, PL, 2006) |
| "CDP-choline was used as the brain activator, and the effect of the intrathecally infused drug was investigated clinically." | 1.26 | Intrathecal pharmacotherapy in coma. ( Ogashiwa, M; Takeuchi, K, 1976) |
| "CDP-choline was used as the brain activator, and the effect of the drug intrathecally infused was investigated both clinically and by experiments on animals." | 1.25 | Studies on the intrathecal pharmacotherapy. Part I: CDP-choline. ( Hara, M; Ogashiwa, M; Okada, J; Takeuchi, K; Tanaka, Y, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (12.50) | 18.7374 |
| 1990's | 9 (11.25) | 18.2507 |
| 2000's | 34 (42.50) | 29.6817 |
| 2010's | 21 (26.25) | 24.3611 |
| 2020's | 6 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Zhu, L | 1 |
| Dai, Y | 1 |
| Zhang, Z | 1 |
| Huang, L | 1 |
| Wang, TJ | 1 |
| Fu, P | 1 |
| Li, Y | 1 |
| Wang, J | 1 |
| Jiang, C | 1 |
| Sheng, M | 1 |
| Guo, T | 1 |
| Mabbott, C | 1 |
| Chau, V | 1 |
| Synnes, A | 1 |
| de Vries, LS | 1 |
| Grunau, RE | 1 |
| Miller, SP | 2 |
| Curioni, CC | 1 |
| Mocellin, MC | 1 |
| Tavares, MDS | 1 |
| da Silva, ACF | 1 |
| de Velasco, PC | 1 |
| Ribas, SA | 1 |
| Lamarca, F | 1 |
| André, C | 1 |
| Lei, X | 1 |
| Qin, D | 1 |
| Zhu, G | 1 |
| Chen, AM | 1 |
| Gerhalter, T | 1 |
| Dehkharghani, S | 1 |
| Peralta, R | 1 |
| Gajdošík, M | 2 |
| Tordjman, M | 1 |
| Zabludovsky, J | 1 |
| Sheriff, S | 1 |
| Ahn, S | 1 |
| Babb, JS | 4 |
| Bushnik, T | 1 |
| Zarate, A | 1 |
| Silver, JM | 3 |
| Im, BS | 1 |
| Wall, SP | 1 |
| Madelin, G | 1 |
| Kirov, II | 5 |
| Anazodo, UC | 1 |
| Wong, DY | 1 |
| Théberge, J | 1 |
| Dacey, M | 1 |
| Gomes, J | 1 |
| Penny, JD | 1 |
| van Ginkel, M | 1 |
| Poirier, SE | 1 |
| McIntyre, CW | 1 |
| Pradhan, K | 1 |
| Das, G | 1 |
| Khan, J | 1 |
| Gupta, V | 1 |
| Barman, S | 1 |
| Adak, A | 1 |
| Ghosh, S | 1 |
| Basu, SK | 1 |
| Pradhan, S | 1 |
| Kapse, K | 1 |
| McCarter, R | 1 |
| Murnick, J | 1 |
| Chang, T | 1 |
| Limperopoulos, C | 1 |
| Hetherington, HP | 1 |
| Hamid, H | 1 |
| Kulas, J | 1 |
| Ling, G | 1 |
| Bandak, F | 1 |
| de Lanerolle, NC | 1 |
| Pan, JW | 1 |
| Guseva, MV | 2 |
| Kamenskii, AA | 1 |
| Gusev, VB | 1 |
| Kierans, AS | 1 |
| Gonen, O | 4 |
| Haemer, G | 1 |
| Nisenbaum, E | 1 |
| Grossman, RI | 4 |
| Lui, YW | 3 |
| Chen, WS | 1 |
| Li, JJ | 1 |
| Zhang, JH | 1 |
| Hong, L | 1 |
| Xing, ZB | 1 |
| Wang, F | 1 |
| Li, CQ | 1 |
| Grossman, EJ | 1 |
| Novikov, DS | 1 |
| Davitz, MS | 1 |
| Inglese, M | 1 |
| Fieremans, E | 1 |
| Tian, R | 1 |
| Han, L | 1 |
| Hou, Z | 1 |
| Hao, S | 1 |
| Mao, X | 1 |
| Zhu, Z | 1 |
| Tao, X | 1 |
| Zhang, Q | 1 |
| Liu, B | 1 |
| Hoch, SE | 1 |
| Tal, A | 2 |
| Hopkins, DM | 1 |
| Scheff, SW | 1 |
| Pauly, JR | 1 |
| Donat, CK | 1 |
| Schuhmann, MU | 2 |
| Voigt, C | 1 |
| Nieber, K | 1 |
| Deuther-Conrad, W | 1 |
| Brust, P | 1 |
| Maudsley, AA | 2 |
| Domenig, C | 1 |
| Govind, V | 2 |
| Darkazanli, A | 1 |
| Studholme, C | 1 |
| Arheart, K | 1 |
| Bloomer, C | 1 |
| McAllister, TW | 1 |
| Arciniegas, DB | 1 |
| Sarmento, E | 1 |
| Moreira, P | 1 |
| Brito, C | 1 |
| Souza, J | 1 |
| Jevoux, C | 1 |
| Bigal, M | 1 |
| Lescot, T | 1 |
| Fulla-Oller, L | 2 |
| Po, C | 1 |
| Chen, XR | 1 |
| Puybasset, L | 1 |
| Gillet, B | 1 |
| Plotkine, M | 1 |
| Meric, P | 1 |
| Marchand-Leroux, C | 1 |
| Ficek, K | 1 |
| Blamek, S | 1 |
| Syguła, D | 1 |
| Miszczyk, L | 1 |
| Sońta-Jakimczyk, D | 1 |
| Tarnawski, R | 1 |
| Babikian, T | 2 |
| Marion, SD | 1 |
| Copeland, S | 1 |
| Alger, JR | 1 |
| O'Neill, J | 1 |
| Cazalis, F | 1 |
| Mink, R | 1 |
| Giza, CC | 1 |
| Vu, JA | 1 |
| Hilleary, SM | 1 |
| Kernan, CL | 1 |
| Newman, N | 1 |
| Asarnow, RF | 1 |
| Zahr, NM | 1 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Hasak, MP | 1 |
| Hsu, O | 1 |
| Vinco, S | 1 |
| Orduna, J | 1 |
| Luong, R | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| Gold, S | 1 |
| Kaliannan, K | 1 |
| Saigal, G | 1 |
| Falcone, S | 1 |
| Arheart, KL | 1 |
| Harris, L | 1 |
| Jagid, J | 1 |
| Rao, V | 1 |
| Munro, CA | 1 |
| Rosenberg, P | 1 |
| Ward, J | 1 |
| Bertrand, M | 1 |
| Degoankar, M | 1 |
| Horská, A | 1 |
| Pham, D | 1 |
| Yousem, DM | 1 |
| Barker, PB | 2 |
| BORNSTEIN, MB | 1 |
| Capizzano, AA | 1 |
| Jorge, RE | 1 |
| Robinson, RG | 1 |
| Johnson, B | 1 |
| Zhang, K | 1 |
| Gay, M | 1 |
| Neuberger, T | 1 |
| Horovitz, S | 1 |
| Hallett, M | 1 |
| Sebastianelli, W | 1 |
| Slobounov, S | 1 |
| Dzhala, V | 1 |
| Valeeva, G | 1 |
| Glykys, J | 1 |
| Khazipov, R | 1 |
| Staley, K | 1 |
| Li, H | 1 |
| Li, JP | 1 |
| Lin, CG | 1 |
| Liu, XW | 1 |
| Geng, ZJ | 1 |
| Mo, YX | 1 |
| Zhang, R | 1 |
| Xie, CM | 1 |
| Semenova, NA | 1 |
| Akhadov, TA | 1 |
| Petryaykin, AV | 1 |
| Sidorin, SS | 1 |
| Lukovenkov, AV | 1 |
| Varfolomeev, SD | 1 |
| Signoretti, S | 2 |
| Marmarou, A | 2 |
| Fatouros, P | 1 |
| Hoyle, R | 1 |
| Beaumont, A | 1 |
| Sawauchi, S | 1 |
| Bullock, R | 1 |
| Young, H | 1 |
| Macmillan, CS | 1 |
| Wild, JM | 1 |
| Wardlaw, JM | 1 |
| Andrews, PJ | 1 |
| Marshall, I | 1 |
| Easton, VJ | 1 |
| Uzan, M | 1 |
| Albayram, S | 1 |
| Dashti, SG | 1 |
| Aydin, S | 1 |
| Hanci, M | 1 |
| Kuday, C | 1 |
| Stiller, D | 1 |
| Skardelly, M | 1 |
| Bernarding, J | 1 |
| Klinge, PM | 1 |
| Samii, A | 1 |
| Samii, M | 1 |
| Brinker, T | 1 |
| KONDO, Y | 1 |
| TANAKAMARU, S | 1 |
| McQuillen, PS | 1 |
| Vigneron, DB | 1 |
| Glidden, DV | 1 |
| Barkovich, AJ | 1 |
| Ferriero, DM | 1 |
| Hamrick, SE | 1 |
| Azakie, A | 1 |
| Karl, TR | 1 |
| Parry, L | 1 |
| Shores, A | 1 |
| Rae, C | 1 |
| Kemp, A | 1 |
| Waugh, MC | 1 |
| Chaseling, R | 1 |
| Joy, P | 1 |
| Ashwal, S | 4 |
| Holshouser, B | 1 |
| Tong, K | 1 |
| Serna, T | 1 |
| Osterdock, R | 1 |
| Gross, M | 1 |
| Kido, D | 1 |
| Shutter, L | 1 |
| Tong, KA | 2 |
| Holshouser, BA | 4 |
| Hunter, JV | 1 |
| Thornton, RJ | 1 |
| Wang, ZJ | 1 |
| Levin, HS | 1 |
| Roberson, G | 1 |
| Brooks, WM | 3 |
| Swank, PR | 1 |
| Payen, JF | 1 |
| Francony, G | 1 |
| Fauvage, B | 1 |
| Le Bas, JF | 1 |
| Choi, CB | 1 |
| Kim, HY | 1 |
| Han, DY | 1 |
| Kang, YW | 1 |
| Han, YM | 1 |
| Jeun, SS | 1 |
| Choe, BY | 1 |
| Spaeth, N | 1 |
| Wyss, MT | 1 |
| Pahnke, J | 1 |
| Biollaz, G | 1 |
| Lutz, A | 1 |
| Goepfert, K | 1 |
| Westera, G | 1 |
| Treyer, V | 1 |
| Weber, B | 1 |
| Buck, A | 1 |
| Schuff, N | 1 |
| Meyerhoff, DJ | 1 |
| Mueller, S | 1 |
| Chao, L | 1 |
| Sacrey, DT | 1 |
| Laxer, K | 1 |
| Weiner, MW | 1 |
| Halbower, AC | 1 |
| Degaonkar, M | 1 |
| Earley, CJ | 1 |
| Marcus, CL | 1 |
| Smith, PL | 1 |
| Prahme, MC | 1 |
| Mahone, EM | 1 |
| Yeo, RA | 2 |
| Phillips, JP | 1 |
| Jung, RE | 2 |
| Brown, AJ | 1 |
| Campbell, RC | 1 |
| Scremin, OU | 2 |
| Li, MG | 1 |
| Roch, M | 1 |
| Booth, R | 1 |
| Jenden, DJ | 2 |
| Gardner-Nichols, J | 1 |
| Freier, MC | 1 |
| Nakabayashi, M | 1 |
| Suzaki, S | 1 |
| Tomita, H | 1 |
| Kirov, I | 1 |
| Fleysher, L | 1 |
| Bennouna, M | 1 |
| Greene, VB | 1 |
| Defranoux, L | 1 |
| Aygok, GA | 1 |
| Fatouros, PP | 1 |
| Portella, G | 1 |
| Bullock, RM | 1 |
| Casey, PA | 1 |
| McKenna, MC | 1 |
| Fiskum, G | 1 |
| Saraswati, M | 1 |
| Robertson, CL | 1 |
| Gadisseux, P | 1 |
| Ward, JD | 1 |
| Young, HF | 1 |
| Becker, DP | 1 |
| Flentge, F | 1 |
| Hajonides-van Der Meulen, WM | 1 |
| Lakke, JP | 1 |
| Teelken, AW | 1 |
| Cohadon, F | 1 |
| Richer, E | 1 |
| Poletto, B | 1 |
| Dixon, CE | 1 |
| Bao, J | 1 |
| Bergmann, JS | 1 |
| Johnson, KM | 1 |
| Danielsen, ER | 1 |
| Michaelis, T | 1 |
| Ross, BD | 1 |
| Lyeth, BG | 1 |
| Jiang, JY | 1 |
| Robinson, SE | 1 |
| Guo, H | 1 |
| Jenkins, LW | 1 |
| Hinshaw, DB | 2 |
| Schell, RM | 1 |
| Bailey, L | 1 |
| Luh, GY | 1 |
| Shu, S | 1 |
| Kahlon, S | 1 |
| Auld, KL | 1 |
| Tomasi, LG | 1 |
| Perkin, RM | 1 |
| Ricci, R | 1 |
| Barbarella, G | 1 |
| Musi, P | 1 |
| Boldrini, P | 1 |
| Trevisan, C | 1 |
| Basaglia, N | 1 |
| Schmidt, RH | 3 |
| Scholten, KJ | 3 |
| Maughan, PH | 3 |
| Garnett, MR | 3 |
| Blamire, AM | 3 |
| Rajagopalan, B | 3 |
| Styles, P | 3 |
| Cadoux-Hudson, TA | 3 |
| Stidley, CA | 1 |
| Petropoulos, H | 1 |
| Weers, DC | 1 |
| Friedman, SD | 1 |
| Barlow, MA | 1 |
| Sibbitt, WL | 1 |
| Corkill, RG | 2 |
| Manners, DN | 1 |
| Young, JD | 1 |
| Khiat, A | 1 |
| Yared, Z | 1 |
| Bard, C | 1 |
| Lacroix, A | 1 |
| Boulanger, Y | 1 |
| Ogashiwa, M | 2 |
| Takeuchi, K | 2 |
| Tanji, H | 1 |
| Takahashi, M | 1 |
| Masu, K | 1 |
| Kawaguchi, Y | 1 |
| Abe, H | 1 |
| Hara, M | 1 |
| Tanaka, Y | 1 |
| Okada, J | 1 |
| Casamenti, F | 1 |
| Milan, F | 1 |
| Pepeu, G | 1 |
| Wakisaka, J | 1 |
| Kuramoto, S | 1 |
| Takamiya, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for choline and Brain Injuries
| Article | Year |
|---|---|
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials.
Topics: Acetylcysteine; Brain Injuries; Cerebral Palsy; Child; Choline; Docosahexaenoic Acids; Female; Fetal | 2022 |
Depression and cognitive complaints following mild traumatic brain injury.
Topics: Antidepressive Agents, Tricyclic; Brain; Brain Injuries; Central Nervous System Stimulants; Choline; | 2009 |
[Contribution of magnetic resonance spectroscopy in predicting severity and outcome in traumatic brain injury].
Topics: Animals; Aspartic Acid; Biomarkers; Brain Chemistry; Brain Injuries; Choline; Craniocerebral Trauma; | 2005 |
N-acetylaspartate as a marker of neuronal injury in neurodegenerative disease.
Topics: Aging; Alcoholism; Amyotrophic Lateral Sclerosis; Aspartic Acid; Biomarkers; Brain; Brain Injuries; | 2006 |
Susceptibility-weighted imaging and proton magnetic resonance spectroscopy in assessment of outcome after pediatric traumatic brain injury.
Topics: Aspartic Acid; Axons; Brain Injuries; Child; Choline; Creatine; Humans; Imaging, Three-Dimensional; | 2006 |
[Cholinergic hypothesis in psychosis following traumatic brain injury and cholinergic hypothesis in schizophrenia: a link?].
Topics: Brain Injuries; Choline; Humans; Psychotic Disorders; Schizophrenia | 2007 |
Nutrition and the neurosurgical patient.
Topics: Acetylcholine; Brain; Brain Injuries; Brain Neoplasms; Catecholamines; Choline; Endocrine Glands; En | 1984 |
5 trials available for choline and Brain Injuries
| Article | Year |
|---|---|
An experimental study on acute brain radiation injury: dynamic changes in proton magnetic resonance spectroscopy and the correlation with histopathology.
Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Magnetic Resonance Spectroscopy; Protons; Rabbits; | 2012 |
Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Follow-Up Studies; Huma | 2008 |
[A precursor of phospholipids in the treatment of severe traumatic comas].
Topics: Adult; Aged; Brain Injuries; Choline; Clinical Trials as Topic; Coma; Cytidine Diphosphate Choline; | 1982 |
Evidence for cellular damage in normal-appearing white matter correlates with injury severity in patients following traumatic brain injury: A magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aged; Amnesia; Aspartic Acid; Axons; Brain Chemistry; Brain Injuries; Cerebral Co | 2000 |
Early proton magnetic resonance spectroscopy in normal-appearing brain correlates with outcome in patients following traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Chemistry; Brain Injuries; Choline; Creatine; Disabili | 2000 |
68 other studies available for choline and Brain Injuries
| Article | Year |
|---|---|
Diet-Induced High Serum Levels of Trimethylamine-N-oxide Enhance the Cellular Inflammatory Response without Exacerbating Acute Intracerebral Hemorrhage Injury in Mice.
Topics: Acute Disease; Animals; Astrocytes; Brain Injuries; Cerebral Hemorrhage; Choline; Diet; Disease Mode | 2022 |
Ventricular Volume in Infants Born Very Preterm: Relationship with Brain Maturation and Neurodevelopment at Age 4.5 Years.
Topics: Brain; Brain Injuries; Cerebral Hemorrhage; Child; Child, Preschool; Choline; Diffusion Tensor Imagi | 2022 |
To Investigate the Effect of Magnetic Resonance Imaging (MRI) and Diffusion Tensor Imaging (DTI) in the Diagnosis of Mild Craniocerebral Injury.
Topics: Brain Injuries; Brain Injuries, Traumatic; Choline; Coma; Creatinine; Diffusion Tensor Imaging; Huma | 2022 |
Replicability of proton MR spectroscopic imaging findings in mild traumatic brain injury: Implications for clinical applications.
Topics: Adult; Aspartic Acid; Brain; Brain Concussion; Brain Injuries; Choline; Creatine; Female; Humans; Ma | 2023 |
Hemodialysis-Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy.
Topics: Aged; Aspartic Acid; Brain; Brain Injuries; Choline; Diffusion Tensor Imaging; Female; Humans; Magne | 2023 |
Neuro-Regenerative Choline-Functionalized Injectable Graphene Oxide Hydrogel Repairs Focal Brain Injury.
Topics: Animals; Brain Injuries; Cells, Cultured; Choline; Female; Graphite; Hydrogels; Injections, Intraven | 2019 |
Third Trimester Cerebellar Metabolite Concentrations are Decreased in Very Premature Infants with Structural Brain Injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cerebellum; Choline; Creatine; Female; Gestational Age; Gray M | 2019 |
MRSI of the medial temporal lobe at 7 T in explosive blast mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Biomarkers; Blast Injuries; Brain Injuries; Choline; Creatine; Explosions; Fem | 2014 |
Optimization of choline administration regimen for correction of cognitive functions in rats after brain injury.
Topics: Administration, Oral; alpha7 Nicotinic Acetylcholine Receptor; Animals; Body Weight; Brain; Brain In | 2013 |
Myoinositol and glutamate complex neurometabolite abnormality after mild traumatic brain injury.
Topics: Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Caudate Nucleus; Choline; Corpus Striatu | 2014 |
Magnetic resonance spectroscopic imaging of brain injury after nasopharyngeal cancer radiation in early delayed reaction.
Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Humans; Magnetic Resonance Imaging; | 2014 |
N-acetyl-aspartate levels correlate with intra-axonal compartment parameters from diffusion MRI.
Topics: Adult; Aspartic Acid; Axons; Brain; Brain Injuries; Choline; Creatine; Diffusion Magnetic Resonance | 2015 |
Neuroprotective efficacy of decompressive craniectomy after controlled cortical impact injury in rats: An MRI study.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Choline; Creatine; Decompressive Craniec | 2015 |
When are metabolic ratios superior to absolute quantification? A statistical analysis.
Topics: Adult; Algorithms; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Data Interpretation, S | 2017 |
Dietary choline supplementation improves behavioral, histological, and neurochemical outcomes in a rat model of traumatic brain injury.
Topics: Animals; Brain Injuries; Choline; Dietary Supplements; Disease Models, Animal; Male; Maze Learning; | 2008 |
Time-dependent alterations of cholinergic markers after experimental traumatic brain injury.
Topics: Animals; Autoradiography; Brain; Brain Injuries; Choline; Disease Models, Animal; Male; Rats; Rats, | 2008 |
Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI).
Topics: Adolescent; Adult; Aging; Algorithms; Brain; Brain Injuries; Choline; Female; Humans; Image Enhancem | 2009 |
Proton spectroscopy in patients with post-traumatic headache attributed to mild head injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Brain Ma | 2009 |
Temporal and regional changes after focal traumatic brain injury.
Topics: Animals; Aspartic Acid; Brain; Brain Edema; Brain Injuries; Brain Mapping; Cerebral Cortex; Choline; | 2010 |
Evaluation of the late effects of CNS prophylactic treatment in childhood acute lymphoblastic leukemia (ALL) using magnetic resonance spectroscopy.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Child, Preschool; Choline; C | 2010 |
Metabolic levels in the corpus callosum and their structural and behavioral correlates after moderate to severe pediatric TBI.
Topics: Adolescent; Age Factors; Aging; Anisotropy; Aspartic Acid; Axons; Biomarkers; Brain Injuries; Child; | 2010 |
Brain injury and recovery following binge ethanol: evidence from in vivo magnetic resonance spectroscopy.
Topics: Alcoholism; Analysis of Variance; Animals; Aspartic Acid; Body Weight; Brain Injuries; Brain Mapping | 2010 |
Whole-brain proton MR spectroscopic imaging of mild-to-moderate traumatic brain injury and correlation with neuropsychological deficits.
Topics: Adolescent; Adult; Aspartic Acid; Biomarkers; Brain; Brain Injuries; Choline; Cognition Disorders; C | 2010 |
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study.
Topics: Adult; Aspartic Acid; Basal Ganglia; Brain; Brain Injuries; Case-Control Studies; Choline; Cognition | 2010 |
Presence and action of acetylcholine in experimental brain trauma.
Topics: Acetylcholine; Brain; Brain Diseases; Brain Injuries; Choline | 1946 |
Limbic metabolic abnormalities in remote traumatic brain injury and correlation with psychiatric morbidity and social functioning.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases, Metabolic; Brain Injuries; Brain Mapping; Ca | 2010 |
Metabolic alterations in corpus callosum may compromise brain functional connectivity in MTBI patients: an 1H-MRS study.
Topics: Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Corpus Callosum; Creatine; Female; Hip | 2012 |
Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Ant | 2012 |
Metabolic dysfunction and relationship in human frontoparietal cortex in severe traumatic brain injury: single-voxel (1)H magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Cerebral Cortex; Child; Child, Preschool; Choline; | 2012 |
Diffuse axonal injury in mild traumatic brain injury: a 3D multivoxel proton MR spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Brain Mapping; Choline; Creatine; Diffuse Axonal I | 2013 |
Application of chemical shift imaging for measurement of NAA in head injured patients.
Topics: Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatinine; Humans; Magnetic Resonance Imaging; | 2002 |
Traumatic brain injury and subarachnoid hemorrhage: in vivo occult pathology demonstrated by magnetic resonance spectroscopy may not be "ischaemic". A primary study and review of the literature.
Topics: Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Brain Ischemia; Child; Choline; Creatine; C | 2002 |
Thalamic proton magnetic resonance spectroscopy in vegetative state induced by traumatic brain injury.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Child; Choline; Creatine; Diffuse Axonal Inj | 2003 |
Metabolic changes in the vicinity of brain contusions: a proton magnetic resonance spectroscopy and histology study.
Topics: Animals; Aspartic Acid; Biomarkers; Brain Injuries; Choline; Creatine; Functional Laterality; Glutam | 2003 |
[EXPERIMENTAL STUDY ON THE THERAPEUTIC USE OF CYTIDINE NUCLEOTIDES FOR THE BRAIN INJURY].
Topics: Brain Injuries; Cats; Choline; Cytidine; Electroencephalography; Humans; Hypothermia; Hypothermia, I | 1963 |
[EXPERIMENTAL AND CLINICAL STUDIES ON CDP-CHOLINE THERAPY FOR BRAIN INJURIES].
Topics: Animals; Biomedical Research; Brain Injuries; Choline; Cytidine Diphosphate Choline; Lagomorpha; Nuc | 1964 |
Preoperative brain injury in newborns with transposition of the great arteries.
Topics: Brain Injuries; Cardiopulmonary Bypass; Choline; Gestational Age; Humans; Infant, Newborn; Lactic Ac | 2004 |
An investigation of neuronal integrity in severe paediatric traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain Injuries; Child; Choline; Cognition Disorders; Creatin | 2004 |
Proton MR spectroscopy detected glutamate/glutamine is increased in children with traumatic brain injury.
Topics: Adolescent; Age Factors; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Com | 2004 |
Proton MRS in acute traumatic brain injury: role for glutamate/glutamine and choline for outcome prediction.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Cerebral Cortex; Choline; Creatinine; Evoked | 2004 |
Late proton MR spectroscopy in children after traumatic brain injury: correlation with cognitive outcomes.
Topics: Adolescent; Aspartic Acid; Brain; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; C | 2005 |
In vivo 1H MR spectroscopic findings in traumatic contusion of ICR mouse brain induced by fluid percussion injury.
Topics: Animals; Aspartic Acid; Brain Injuries; Choline; Creatine; Magnetic Resonance Spectroscopy; Male; Mi | 2005 |
Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L: -tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat.
Topics: Animals; Blood-Brain Barrier; Brain Injuries; Brain Neoplasms; Cell Line, Tumor; Choline; Fluorodeox | 2006 |
Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Cerebral Cortex; Child; Choline; Cr | 2006 |
Magnetic resonance spectroscopy detects brain injury and predicts cognitive functioning in children with brain injuries.
Topics: Adolescent; Aspartic Acid; Brain Injuries; Case-Control Studies; Child; Choline; Cognition; Creatine | 2006 |
Acetylcholine and choline dynamics provide early and late markers of traumatic brain injury.
Topics: Acetylcholine; Analysis of Variance; Animals; Brain Injuries; Choline; Choline O-Acetyltransferase; | 2006 |
Neural injury and recovery near cortical contusions: a clinical magnetic resonance spectroscopy study.
Topics: Adolescent; Adult; Aspartic Acid; Brain Injuries; Case-Control Studies; Choline; Creatine; Female; G | 2007 |
Characterizing 'mild' in traumatic brain injury with proton MR spectroscopy in the thalamus: Initial findings.
Topics: Adult; Aspartic Acid; Brain Injuries; Choline; Creatine; Female; Glasgow Coma Scale; Humans; Magneti | 2007 |
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C | 2008 |
CSF choline levels in groups of patients with cranial trauma or extrapyramidal disorders.
Topics: Adult; Basal Ganglia Diseases; Blood-Brain Barrier; Brain Concussion; Brain Injuries; Choline; Femal | 1984 |
Traumatic brain injury reduces hippocampal high-affinity [3H]choline uptake but not extracellular choline levels in rats.
Topics: Acetylcholine; Animals; Biological Transport; Brain Injuries; Choline; Craniotomy; Extracellular Spa | 1994 |
Three methods of calibration in quantitative proton MR spectroscopy.
Topics: Adult; Aspartic Acid; Body Water; Brain; Brain Chemistry; Brain Injuries; Calibration; Choline; Crea | 1995 |
Hypothermia blunts acetylcholine increase in CSF of traumatically brain injured rats.
Topics: Acetylcholine; Animals; Body Temperature; Brain; Brain Injuries; Choline; Hypothermia, Induced; Rats | 1993 |
Cholinergic control of cerebral blood flow in stroke, trauma and aging.
Topics: Acetylcholine; Aging; Animals; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Choline; | 1996 |
Proton magnetic resonance spectroscopy in the evaluation of children with congenital heart disease and acute central nervous system injury.
Topics: Aspartic Acid; Brain; Brain Injuries; Cardiopulmonary Bypass; Case-Control Studies; Child, Preschool | 1996 |
Proton MR spectroscopy after acute central nervous system injury: outcome prediction in neonates, infants, and children.
Topics: Adolescent; Aspartic Acid; Brain; Brain Diseases; Brain Injuries; Child; Choline; Discriminant Analy | 1997 |
Localised proton MR spectroscopy of brain metabolism changes in vegetative patients.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain; Brain Injuries; Child; Child, Preschool; Choline; Cre | 1997 |
Time course for recovery of water maze performance and central cholinergic innervation after fluid percussion injury.
Topics: Animals; Brain; Brain Injuries; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Cholinergic F | 1999 |
Metabolic and cognitive response to human traumatic brain injury: a quantitative proton magnetic resonance study.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Injuries; Choline; Cognition Disorders; Creatinine; Cr | 2000 |
Cognitive impairment and synaptosomal choline uptake in rats following impact acceleration injury.
Topics: Acceleration; Animals; Binding, Competitive; Brain; Brain Injuries; Choline; Cognition Disorders; Ma | 2000 |
Recovery of water maze performance in aged versus young rats after brain injury with the impact acceleration model.
Topics: Acceleration; Aging; Animals; Binding, Competitive; Brain; Brain Injuries; Choline; Male; Maze Learn | 2000 |
Altered cellular metabolism following traumatic brain injury: a magnetic resonance spectroscopy study.
Topics: Adenosine Triphosphate; Adolescent; Adult; Aspartic Acid; Brain; Brain Injuries; Choline; Creatine; | 2001 |
Long-term brain metabolic alterations in exogenous Cushing's syndrome as monitored by proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Injuries; Cell Membrane; Choline; Crea | 2001 |
Intrathecal pharmacotherapy in coma.
Topics: Adult; Aged; Brain Injuries; Choline; Coma; Cytidine Diphosphate Choline; Electroencephalography; Fe | 1976 |
Intrathecal administration of CDP-choline into the lower lumbar subarachnoid space in two patients with post-traumatic akinetic mutism.
Topics: Aged; Akinetic Mutism; Brain Injuries; Choline; Cytidine Diphosphate Choline; Humans; Injections, Sp | 1976 |
Studies on the intrathecal pharmacotherapy. Part I: CDP-choline.
Topics: Adolescent; Adult; Aged; Animals; Autoradiography; Brain; Brain Death; Brain Injuries; Choline; Cons | 1975 |
Lesions of the nucleus basalis magnocellularis in the rat: morphological, biochemical and behavioral reparative effect of nerve growth factor and ganglioside GM1.
Topics: Animals; Brain Injuries; Cerebral Cortex; Choline; Choline O-Acetyltransferase; G(M1) Ganglioside; M | 1990 |
[Effects of various drugs on the mechanism of recovery of the impaired brain].
Topics: Animals; Brain; Brain Injuries; Carbon Dioxide; Choline; Cytochromes; Glycogen; Histocytochemistry; | 1968 |